On Wed, 15 Sep 2010 10:43:35 -0700, Daniel Goldin <danielgoldin@gmail.com> wrote:
> 1) How to add to a the poll script to skip inbox and add particular tag for
> certain emails -- in particular listserv emails. Any example poll
> scripts would be greatly appreciated.

The wiki is becoming a good place to look for all kinds of useful info.
see:

http://notmuchmail.org/initial_tagging/

> 2) Is it possible to create a keybinding that would remove all tags and
> add a "delete" tag?

Didn't I just answer this question the other day [0]?

http://notmuchmail.org/emacstips/

jamie.

[0] id:87bp80jhmw.fsf@servo.finestructure.net