Good catch for Libreoffice, I didn't thought about that since I use to open LO files with Thunar (it raise an other question : how to set GUIX_LOCPATH for applications that I do not from command line, but it's not related to guix).

I just have to add GUIX_LOCPATH to ~/.xsessionrc and it works for LibreOffice AND zsh !!

Don't understand why setting it in ~/.zshrc wasn't enough ??

Anyway, thanks for pointing me to the right direction !