I should probably give some more details.  Here is the bootloader config I'm using

 (bootloader
  (bootloader-configuration
   (bootloader grub-efi-bootloader)
   (targets (list "/boot/efi"))
   (keyboard-layout keyboard-layout)))

My mounts look like:
/dev/mapper/jake /mnt/jake # with -o subvol=guix
/dev/mapper/jake /mnt/jake/swap # with -o subvol=swap
/dev/sdb2 /mnt/jake/boot/efi

I've been using the same system config without problem, and just changed the bootloader config to the above

-zacchaeus

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