Jumping in here to share some of my own info as I'm having the same issue. brad@kazuki:~/ > nvim zsh: segmentation fault nvim I've got neovim installed in the system profile (so root has a comfortable editor instead of just nano) guix (GNU Guix) d22d246a256814784dfb03437949bdc2efd746a5 brad@kazuki:~/ > echo $TERM screen-256color Here is my $TERM. I am running inside tmux using termite as my terminal emulator. For the record I get the same segmentation fault outside of tmux using the same terminal emulator. brad@kazuki:~/ > echo $TERM xterm-termite I tried the guix environment --container command that Ricardo shared and in that instance nvim works for me in tmux just fine as well. If there's more info about my environment I can share to help track down the issue, please let me know.