Well I just tried, reading that it's doable, according to section 4.2 of the manual. ​So I added ​one line right after (build-system gnu-build-system) : (arguments '(#:phases (modify-phases %standard-phases (delete 'configure)))) And logically the outcome changed : phase `unpack' succeeded after 0.1 seconds starting phase `patch-usr-bin-file' phase `patch-usr-bin-file' succeeded after 0.0 seconds starting phase `patch-source-shebangs' phase `patch-source-shebangs' succeeded after 0.1 seconds starting phase `patch-generated-file-shebangs' phase `patch-generated-file-shebangs' succeeded after 0.2 seconds starting phase `build' make: *** No targets specified and no makefile found. Stop. phase `build' failed after 0.1 seconds builder for `/gnu/store/s0diig2i0533r6sl7iib9pmskpx8ri4a-freefilesync-9.9.drv' failed with exit code 1 @ build-failed /gnu/store/s0diig2i0533r6sl7iib9pmskpx8ri4a-freefilesync-9.9.drv - 1 builder for `/gnu/s tore/s0diig2i0533r6sl7iib9pmskpx8ri4a-freefilesync-9.9.drv' failed with exit code 1 guix build: error: build failed: build of `/gnu/store/s0diig2i0533r6sl7iib9pmskpx8ri4a-freefilesync-9.9 .drv' failed arnaud@brix ~/guix_packages/gnu/packages$ Getting late tonight but tomorrow pointing directly to the provided Makefile might help ? Cheers and thanks for reading so far :)