Hi Felix, Thank you for the patches! I've applied v3 on my local checkout, it passed lint and build. It looks good for me Some of the packages were failed to build after patches are applied, I've adjusted some of them (relax requirement, bump versions, disable more failing tests). Changes included in v4 of the series. This update is quite expensive as it trigger rebuild of python-scipy. --8<---------------cut here---------------start------------->8--- ./pre-inst-env guix refresh --list-dependent python-textual python-rich python-pygments-next python-mdit-py-plugins python-markdown-it-py Building the following 124 packages would ensure 301 dependent packages are rebuilt: python-vaex-core@4.13.0 python-enoslib@8.0.1 httpie@3.2.1 pelican@4.7.2 python-textual@0.50.1 pigx-sars-cov-2@0.0.9 trinityrnaseq@2.13.2 python-pynbody@1.5.2 checkm@1.1.3 python-vireosnp@0.5.7 python-ete3@3.1.3 python-hclust2@1.0.0 python-pairtools@1.0.2 flair@1.6.4 umi-tools@1.0.0 python-plastid@0.6.1 python-cmseq@1.0.4 tombo@1.5.1 pigx@0.0.3 variant-tools@3.1.2 python-metpy@1.6.1 python-cartopy@0.22.0 python-graph-tool@2.59 python-iml@0.6.2 pitivi@2022.06.0 perl-cworld-dekker@1.01 ciri-long@1.0.2 python-biofluff@3.0.4 tadbit@1.0.1-1.5c4c1dd clipper@2.0.1 tbsp@1.0.0-2.dc30c03 python-iced@0.5.8 python-velocyto@0.17.17 nanopolish@0.14.0 python-cleanlab@2.2.0 python-gpytorch@1.11 python-mapie@0.8.2 lightgbm@2.0.12 python-funsor@0.4.5 python-bbknn@1.6.0 python-fasttext@0.9.2 python-xgboost@1.5.2 python-ripser@0.6.4 python-hdbscan@0.8.33 python-scikit-learn-extra@0.3.0-1.0f95d8d python-scikit-rebate@0.62 python-scanorama@1.7.2 python-deepdish@0.3.7 python-scikit-allel@1.3.5 python-gpy@1.10.0 python-pyts@0.13.0 python-deepxde@1.10.1 python-modin@0.15.1 python-salib@1.4.7 cura@4.13.1 python-pyjanitor@0.26.0 python-scikit-opt@0.6.6 python-astroalign@2.5.1 python-cooltools@0.5.1 python-jwst@1.12.5 python-scikit-fuzzy@0.4.2 python-pandera@0.17.2 python-pysnptools@0.4.11 python-baltica@1.1.2 python-biom-format@2.1.12 python-magic-impute@1.2.1 python-numpy-documentation@1.23.2 cnvkit@0.9.10 python-cesium@0.12.1 python-scikit-rf@0.31.0 orange@3.32.0 python-pydub@0.25.1 python-matplotlib-venn@0.11.5 python-matplotlib-documentation@3.8.2 python-hicexplorer@3.7.2 font-cozette@1.13.0 nototools@0.2.16 gnome@42.4 mate@1.26.1 python-statmake@0.6.0 font-amiri@1.000 weasyprint@56.1 python-sparse@0.14.0 qspectrumanalyzer@2.1.0 gr-satellites@4.6.0 gqrx@2.17.3 urh@2.9.4 gnss-sdr@0.0.17 gr-dsd@1.0.0-0.f9b9936 nanovna-saver@0.5.3 python-dolfin-adjoint@2019.1.0 python-commonroad-route-planner@2022.3 python-pymc@5.10.3 python-goatools@1.3.1 python-poliastro@0.17.0 python-pytorch-geometric@2.4.0 python-fanc@0.9.25 python-pyani@0.2.12 stpipeline@1.8.1 python-bulkvis@2.0.0-2.00a82a9 python-phylophlan@3.0.3 instrain@1.5.4 scregseg@0.1.3 python-multivelo@0.1.2 python-ikarus@0.0.2 r-doubletcollection@1.1.0-1.c0d62f1 fanc@0-1.354401e python-demuxem@0.1.7 python-episcanpy@0.4.0 python-liana-py@0.1.9 python-cellbender@0.2.2 python-pingouin@0.5.2 python-statannot@0.2.3 python-openturns@1.21.3 python-spacy@3.5.3 python-pythonanywhere@0.12.1 python-pytest-cookies@0.7.0 python-quadpy@0.16.10 python-cplot@0.9.3 python-pyvista@0.42.3 python-pygmsh@7.1.17 python-sphinx-theme-builder@0.2.0b1 clikan@0.2.1-1.55ab29e jami-docs@0.0.0-2.a48997d --8<---------------cut here---------------end--------------->8--- Failed when patches are applied, might need more time for investigation; - python-dolfin-adjoint@2019.1.0 Packages which were failing before patches are aplied and after: - python-commonroad-route-planner@2022.3 -- Oleg