Dear Guix, I want to add another R package: VariantAnnotation. For this I also had to add another R package called "zlibbioc". Even though we provide zlib in GNU Guix, and it also uses the zlib input instead of zlib provided by this package, it is a required dependency of VariantAnnotation. Instead of customizing the VariantAnnotation package (and deviate from upstream development), I believe this is a fairly nice solution. I hope this is fine with you. Kind regards, Roel Janssen