On Tue, May 22, 2018 at 12:53:43 +0200, Pierre Neidhardt wrote:
> I'm trying to use my nitrokey on GuixSD.

I use a Nitrokey Pro on GuixSD.

>> gpg --card-status
> gpg: selecting openpgp failed: No such device
> gpg: OpenPGP card not available: No such device

Have you started pcscd?  We don't yet have a service for it, so that
needs to be done manually.  When I first log in, I run it as root (just
`sudo pcscd'), and then `gpg --card-status` works as expected.

Can you give that a try?

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Mike Gerwitz
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