*Symptoms* After running guix gc, and rebooting, I got the following errors (which stay something like half a second on the screen): error: no such device: /gnu/store/0fijjh7qw8ppsks0ba3q9m873ljhj797-grub-2.04/share/grub/unicode.pf2 error: file `/gnu/store/0fijjh7qw8ppsks0ba3q9m873ljhj797-grub-2.04/share/grub/unicode.pf2' not found. error: no suitable video mode found. error: no video mode activated. I then get to the grub menu where I can pick which version of Guix I want to boot on, but all of them lead to getting stuck on the following text (with nothing moving after that for at least several minutes): error: no suitable video mode found. Booting in blind mod *Fix * Fortunately nckx was on IRC and saved me by telling me to press C to get the grub command line when I got to the grub menu and run setup_gfxterm. Running guix system reconfigure config.scm removed the need for setup_gfxterm for subsequent boots. *Cause* guix gc thinks that grub (and a lot of other stuff that it shouldn't think is dead) is dead, as shown by the following commands (given by nckx): $ grep unicode /boot/grub/grub.cfg search --file --set /gnu/store/0fijjh7qw8ppsks0ba3q9m873ljhj797-grub-2.04/share/grub/unicode.pf2 if loadfont /gnu/store/0fijjh7qw8ppsks0ba3q9m873ljhj797-grub-2.04/share/grub/unicode.pf2; then $ guix gc --list-dead | grep 0fijjh7qw8ppsks0ba3q9m873ljhj797 finding garbage collector roots... determining live/dead paths... /gnu/store/0fijjh7qw8ppsks0ba3q9m873ljhj797-grub-2.04 I was also able to reproduce the bug by running guix gc and rebooting again.