On Sun, 28 Oct 2018 07:36:38 +0100 Julien Lepiller wrote: > I had a similar issue, with every guix comand failing. It was due to > GUILE_LOAD_PATH and GUILE_LOAD_COMPILED_PATH ending with “:”. Can you > check the value of these variables? Yes, that was the problem here: export GUILE_LOAD_PATH=$HOME/.guix-profile/share/guile/site/2.2:$GUILE_LOAD_PATH Now I learned what that :+:-notation is for and used it: export GUILE_LOAD_PATH=$HOME/.guix-profile/share/guile/site/2.2${GUILE_LOAD_PATH:+:}$GUILE_LOAD_PATH Thanks, Björn