Ludovic Courtès <ludo@gnu.org> writes:

>> Is there a way to make Trisquel's GNOME and its main menu aware of
>> programs installed with Guix?
>
> It should be possible, but I don’t know how.  Anyone?

I don't use Trisquel, but this works for GNOME in Fedora:

  ln -s ~/.guix-profile/share/applications ~/.local/share/applications/guix

You might also want to copy or symlink application icons from
~/.guix-profile/share/icons to ~/.local/share/icons
(don't know how to make them visible to GNOME with a single symlink)

-- 
Mikhail