Marco,

Hullo and welcome!

"Marco Menne" via 写道：
> I searched a lot in the net but did'nt find an useful answer for 
> Guix system.
> I know to blacklist the nouveau graphics driver on boot but how 
> can I blacklist it permanentely?

You don't mention how you do so on boot.

I assume you're talking about adding 
‘modprobe.blacklist=nouveau[,…]’ to the kernel command line[0] in 
GRUB.

You can easily ask[1] Guix to add it to the default kernel command 
line at each boot, like so:

  (operating-system
    […]
    (kernel-arguments
      (cons* "modprobe.blacklist=nouveau[,…]"
             […]
             %default-kernel-arguments))
    […])

Don't forget to reconfigure and optionally reboot.

> My second question is about the hda-intel sound driver. 
> I have hda-intel and nvidia-hdmi sound modules. On Slackware I 
> cloud blacklist the Nvidia driver and could get the intel driver 
> working.
> But as in Guix system there is no /etc/modprobe.d/ folder I 
> don't know how to get my sound working.

You forgot to mention how you'd use /etc/modprobe.d to do so… ;-) 
So here too I can only guess an answer.

If you just want to add default module options, you can do so on 
the kernel command line as well: either manually in GRUB (to test) 
or the kernel-arguments field mentioned above.

For a random example plucked from ‘modinfo snd_hda_intel’: to 
disable power saving, simply add "snd_hda_intel.power_save=0", and 
the kernel will set this option for you whenever snd_hda_intel is 
loaded, no matter when or how or who loads it.

Kind regards,

T G-R

[0]: 
https://guix.gnu.org/manual/devel/en/guix.html#Initial-RAM-Disk
[1]: 
https://guix.gnu.org/manual/devel/en/guix.html#operating_002dsystem-Reference