diff --git a/gnu/packages/emulators.scm b/gnu/packages/emulators.scm
index c1d1d54052..d616f7fd21 100644
--- a/gnu/packages/emulators.scm
+++ b/gnu/packages/emulators.scm
@@ -82,6 +82,7 @@
   #:use-module (gnu packages xorg)
   #:use-module (gnu packages web)
   #:use-module (guix build-system cmake)
+  #:use-module (guix build-system glib-or-gtk)
   #:use-module (guix build-system gnu))
 
 (define-public desmume
@@ -1379,9 +1380,18 @@ functions.  The source code to MAME serves as this documentation.")
        (sha256
         (base32
          "1ha5s6d3y7s9aq9f4zmn9p88109c3mrj36z2w68jhiw5xrxws833"))))
-    (build-system gnu-build-system)
+    (build-system glib-or-gtk-build-system)
+    (supported-systems '("i686-linux" "x86_64-linux"))
     (arguments
-     `(#:system "i686-linux"))
+     `(#:system "i686-linux"
+       #:phases
+       (modify-phases %standard-phases
+         (add-after 'unpack 'fix-CFLAGS
+           (lambda* _
+             ;; Remove GTK API deprecation flags that cause build errors
+             (substitute* "configure"
+               (("GTK_CFLAGS=\"\\$GTK_CFLAGS .*\"") ""))
+             #t)))))
     (native-inputs
      `(("pkg-config" ,pkg-config)
        ("nasm" ,nasm)))