Dear Guix, By updating samtools to 1.11, I introduced a build failure for bedtools. More precisely, the tests for intersect break in precisely this way: https://github.com/arq5x/bedtools2/issues/814 With the following patches, I'd like to add samtools-1.9, htslib-1.9 (samtools depends on that) to fix this problem with bedtools. Alternatively we could add a patch to disable the failing bedtools tests. I manually inspected the test results, and seem to match perfectly (indicating that there's no problem with bedtools). Kind regards, Roel Janssen