unofficial mirror of guix-patches@gnu.org 
 help / color / mirror / code / Atom feed
blob 9dd24d164d3a0cb233900648c37edda88fe080a4 754993 bytes (raw)
name: gnu/packages/cran.scm 	 # note: path name is non-authoritative(*)
    1
    2
    3
    4
    5
    6
    7
    8
    9
   10
   11
   12
   13
   14
   15
   16
   17
   18
   19
   20
   21
   22
   23
   24
   25
   26
   27
   28
   29
   30
   31
   32
   33
   34
   35
   36
   37
   38
   39
   40
   41
   42
   43
   44
   45
   46
   47
   48
   49
   50
   51
   52
   53
   54
   55
   56
   57
   58
   59
   60
   61
   62
   63
   64
   65
   66
   67
   68
   69
   70
   71
   72
   73
   74
   75
   76
   77
   78
   79
   80
   81
   82
   83
   84
   85
   86
   87
   88
   89
   90
   91
   92
   93
   94
   95
   96
   97
   98
   99
  100
  101
  102
  103
  104
  105
  106
  107
  108
  109
  110
  111
  112
  113
  114
  115
  116
  117
  118
  119
  120
  121
  122
  123
  124
  125
  126
  127
  128
  129
  130
  131
  132
  133
  134
  135
  136
  137
  138
  139
  140
  141
  142
  143
  144
  145
  146
  147
  148
  149
  150
  151
  152
  153
  154
  155
  156
  157
  158
  159
  160
  161
  162
  163
  164
  165
  166
  167
  168
  169
  170
  171
  172
  173
  174
  175
  176
  177
  178
  179
  180
  181
  182
  183
  184
  185
  186
  187
  188
  189
  190
  191
  192
  193
  194
  195
  196
  197
  198
  199
  200
  201
  202
  203
  204
  205
  206
  207
  208
  209
  210
  211
  212
  213
  214
  215
  216
  217
  218
  219
  220
  221
  222
  223
  224
  225
  226
  227
  228
  229
  230
  231
  232
  233
  234
  235
  236
  237
  238
  239
  240
  241
  242
  243
  244
  245
  246
  247
  248
  249
  250
  251
  252
  253
  254
  255
  256
  257
  258
  259
  260
  261
  262
  263
  264
  265
  266
  267
  268
  269
  270
  271
  272
  273
  274
  275
  276
  277
  278
  279
  280
  281
  282
  283
  284
  285
  286
  287
  288
  289
  290
  291
  292
  293
  294
  295
  296
  297
  298
  299
  300
  301
  302
  303
  304
  305
  306
  307
  308
  309
  310
  311
  312
  313
  314
  315
  316
  317
  318
  319
  320
  321
  322
  323
  324
  325
  326
  327
  328
  329
  330
  331
  332
  333
  334
  335
  336
  337
  338
  339
  340
  341
  342
  343
  344
  345
  346
  347
  348
  349
  350
  351
  352
  353
  354
  355
  356
  357
  358
  359
  360
  361
  362
  363
  364
  365
  366
  367
  368
  369
  370
  371
  372
  373
  374
  375
  376
  377
  378
  379
  380
  381
  382
  383
  384
  385
  386
  387
  388
  389
  390
  391
  392
  393
  394
  395
  396
  397
  398
  399
  400
  401
  402
  403
  404
  405
  406
  407
  408
  409
  410
  411
  412
  413
  414
  415
  416
  417
  418
  419
  420
  421
  422
  423
  424
  425
  426
  427
  428
  429
  430
  431
  432
  433
  434
  435
  436
  437
  438
  439
  440
  441
  442
  443
  444
  445
  446
  447
  448
  449
  450
  451
  452
  453
  454
  455
  456
  457
  458
  459
  460
  461
  462
  463
  464
  465
  466
  467
  468
  469
  470
  471
  472
  473
  474
  475
  476
  477
  478
  479
  480
  481
  482
  483
  484
  485
  486
  487
  488
  489
  490
  491
  492
  493
  494
  495
  496
  497
  498
  499
  500
  501
  502
  503
  504
  505
  506
  507
  508
  509
  510
  511
  512
  513
  514
  515
  516
  517
  518
  519
  520
  521
  522
  523
  524
  525
  526
  527
  528
  529
  530
  531
  532
  533
  534
  535
  536
  537
  538
  539
  540
  541
  542
  543
  544
  545
  546
  547
  548
  549
  550
  551
  552
  553
  554
  555
  556
  557
  558
  559
  560
  561
  562
  563
  564
  565
  566
  567
  568
  569
  570
  571
  572
  573
  574
  575
  576
  577
  578
  579
  580
  581
  582
  583
  584
  585
  586
  587
  588
  589
  590
  591
  592
  593
  594
  595
  596
  597
  598
  599
  600
  601
  602
  603
  604
  605
  606
  607
  608
  609
  610
  611
  612
  613
  614
  615
  616
  617
  618
  619
  620
  621
  622
  623
  624
  625
  626
  627
  628
  629
  630
  631
  632
  633
  634
  635
  636
  637
  638
  639
  640
  641
  642
  643
  644
  645
  646
  647
  648
  649
  650
  651
  652
  653
  654
  655
  656
  657
  658
  659
  660
  661
  662
  663
  664
  665
  666
  667
  668
  669
  670
  671
  672
  673
  674
  675
  676
  677
  678
  679
  680
  681
  682
  683
  684
  685
  686
  687
  688
  689
  690
  691
  692
  693
  694
  695
  696
  697
  698
  699
  700
  701
  702
  703
  704
  705
  706
  707
  708
  709
  710
  711
  712
  713
  714
  715
  716
  717
  718
  719
  720
  721
  722
  723
  724
  725
  726
  727
  728
  729
  730
  731
  732
  733
  734
  735
  736
  737
  738
  739
  740
  741
  742
  743
  744
  745
  746
  747
  748
  749
  750
  751
  752
  753
  754
  755
  756
  757
  758
  759
  760
  761
  762
  763
  764
  765
  766
  767
  768
  769
  770
  771
  772
  773
  774
  775
  776
  777
  778
  779
  780
  781
  782
  783
  784
  785
  786
  787
  788
  789
  790
  791
  792
  793
  794
  795
  796
  797
  798
  799
  800
  801
  802
  803
  804
  805
  806
  807
  808
  809
  810
  811
  812
  813
  814
  815
  816
  817
  818
  819
  820
  821
  822
  823
  824
  825
  826
  827
  828
  829
  830
  831
  832
  833
  834
  835
  836
  837
  838
  839
  840
  841
  842
  843
  844
  845
  846
  847
  848
  849
  850
  851
  852
  853
  854
  855
  856
  857
  858
  859
  860
  861
  862
  863
  864
  865
  866
  867
  868
  869
  870
  871
  872
  873
  874
  875
  876
  877
  878
  879
  880
  881
  882
  883
  884
  885
  886
  887
  888
  889
  890
  891
  892
  893
  894
  895
  896
  897
  898
  899
  900
  901
  902
  903
  904
  905
  906
  907
  908
  909
  910
  911
  912
  913
  914
  915
  916
  917
  918
  919
  920
  921
  922
  923
  924
  925
  926
  927
  928
  929
  930
  931
  932
  933
  934
  935
  936
  937
  938
  939
  940
  941
  942
  943
  944
  945
  946
  947
  948
  949
  950
  951
  952
  953
  954
  955
  956
  957
  958
  959
  960
  961
  962
  963
  964
  965
  966
  967
  968
  969
  970
  971
  972
  973
  974
  975
  976
  977
  978
  979
  980
  981
  982
  983
  984
  985
  986
  987
  988
  989
  990
  991
  992
  993
  994
  995
  996
  997
  998
  999
 1000
 1001
 1002
 1003
 1004
 1005
 1006
 1007
 1008
 1009
 1010
 1011
 1012
 1013
 1014
 1015
 1016
 1017
 1018
 1019
 1020
 1021
 1022
 1023
 1024
 1025
 1026
 1027
 1028
 1029
 1030
 1031
 1032
 1033
 1034
 1035
 1036
 1037
 1038
 1039
 1040
 1041
 1042
 1043
 1044
 1045
 1046
 1047
 1048
 1049
 1050
 1051
 1052
 1053
 1054
 1055
 1056
 1057
 1058
 1059
 1060
 1061
 1062
 1063
 1064
 1065
 1066
 1067
 1068
 1069
 1070
 1071
 1072
 1073
 1074
 1075
 1076
 1077
 1078
 1079
 1080
 1081
 1082
 1083
 1084
 1085
 1086
 1087
 1088
 1089
 1090
 1091
 1092
 1093
 1094
 1095
 1096
 1097
 1098
 1099
 1100
 1101
 1102
 1103
 1104
 1105
 1106
 1107
 1108
 1109
 1110
 1111
 1112
 1113
 1114
 1115
 1116
 1117
 1118
 1119
 1120
 1121
 1122
 1123
 1124
 1125
 1126
 1127
 1128
 1129
 1130
 1131
 1132
 1133
 1134
 1135
 1136
 1137
 1138
 1139
 1140
 1141
 1142
 1143
 1144
 1145
 1146
 1147
 1148
 1149
 1150
 1151
 1152
 1153
 1154
 1155
 1156
 1157
 1158
 1159
 1160
 1161
 1162
 1163
 1164
 1165
 1166
 1167
 1168
 1169
 1170
 1171
 1172
 1173
 1174
 1175
 1176
 1177
 1178
 1179
 1180
 1181
 1182
 1183
 1184
 1185
 1186
 1187
 1188
 1189
 1190
 1191
 1192
 1193
 1194
 1195
 1196
 1197
 1198
 1199
 1200
 1201
 1202
 1203
 1204
 1205
 1206
 1207
 1208
 1209
 1210
 1211
 1212
 1213
 1214
 1215
 1216
 1217
 1218
 1219
 1220
 1221
 1222
 1223
 1224
 1225
 1226
 1227
 1228
 1229
 1230
 1231
 1232
 1233
 1234
 1235
 1236
 1237
 1238
 1239
 1240
 1241
 1242
 1243
 1244
 1245
 1246
 1247
 1248
 1249
 1250
 1251
 1252
 1253
 1254
 1255
 1256
 1257
 1258
 1259
 1260
 1261
 1262
 1263
 1264
 1265
 1266
 1267
 1268
 1269
 1270
 1271
 1272
 1273
 1274
 1275
 1276
 1277
 1278
 1279
 1280
 1281
 1282
 1283
 1284
 1285
 1286
 1287
 1288
 1289
 1290
 1291
 1292
 1293
 1294
 1295
 1296
 1297
 1298
 1299
 1300
 1301
 1302
 1303
 1304
 1305
 1306
 1307
 1308
 1309
 1310
 1311
 1312
 1313
 1314
 1315
 1316
 1317
 1318
 1319
 1320
 1321
 1322
 1323
 1324
 1325
 1326
 1327
 1328
 1329
 1330
 1331
 1332
 1333
 1334
 1335
 1336
 1337
 1338
 1339
 1340
 1341
 1342
 1343
 1344
 1345
 1346
 1347
 1348
 1349
 1350
 1351
 1352
 1353
 1354
 1355
 1356
 1357
 1358
 1359
 1360
 1361
 1362
 1363
 1364
 1365
 1366
 1367
 1368
 1369
 1370
 1371
 1372
 1373
 1374
 1375
 1376
 1377
 1378
 1379
 1380
 1381
 1382
 1383
 1384
 1385
 1386
 1387
 1388
 1389
 1390
 1391
 1392
 1393
 1394
 1395
 1396
 1397
 1398
 1399
 1400
 1401
 1402
 1403
 1404
 1405
 1406
 1407
 1408
 1409
 1410
 1411
 1412
 1413
 1414
 1415
 1416
 1417
 1418
 1419
 1420
 1421
 1422
 1423
 1424
 1425
 1426
 1427
 1428
 1429
 1430
 1431
 1432
 1433
 1434
 1435
 1436
 1437
 1438
 1439
 1440
 1441
 1442
 1443
 1444
 1445
 1446
 1447
 1448
 1449
 1450
 1451
 1452
 1453
 1454
 1455
 1456
 1457
 1458
 1459
 1460
 1461
 1462
 1463
 1464
 1465
 1466
 1467
 1468
 1469
 1470
 1471
 1472
 1473
 1474
 1475
 1476
 1477
 1478
 1479
 1480
 1481
 1482
 1483
 1484
 1485
 1486
 1487
 1488
 1489
 1490
 1491
 1492
 1493
 1494
 1495
 1496
 1497
 1498
 1499
 1500
 1501
 1502
 1503
 1504
 1505
 1506
 1507
 1508
 1509
 1510
 1511
 1512
 1513
 1514
 1515
 1516
 1517
 1518
 1519
 1520
 1521
 1522
 1523
 1524
 1525
 1526
 1527
 1528
 1529
 1530
 1531
 1532
 1533
 1534
 1535
 1536
 1537
 1538
 1539
 1540
 1541
 1542
 1543
 1544
 1545
 1546
 1547
 1548
 1549
 1550
 1551
 1552
 1553
 1554
 1555
 1556
 1557
 1558
 1559
 1560
 1561
 1562
 1563
 1564
 1565
 1566
 1567
 1568
 1569
 1570
 1571
 1572
 1573
 1574
 1575
 1576
 1577
 1578
 1579
 1580
 1581
 1582
 1583
 1584
 1585
 1586
 1587
 1588
 1589
 1590
 1591
 1592
 1593
 1594
 1595
 1596
 1597
 1598
 1599
 1600
 1601
 1602
 1603
 1604
 1605
 1606
 1607
 1608
 1609
 1610
 1611
 1612
 1613
 1614
 1615
 1616
 1617
 1618
 1619
 1620
 1621
 1622
 1623
 1624
 1625
 1626
 1627
 1628
 1629
 1630
 1631
 1632
 1633
 1634
 1635
 1636
 1637
 1638
 1639
 1640
 1641
 1642
 1643
 1644
 1645
 1646
 1647
 1648
 1649
 1650
 1651
 1652
 1653
 1654
 1655
 1656
 1657
 1658
 1659
 1660
 1661
 1662
 1663
 1664
 1665
 1666
 1667
 1668
 1669
 1670
 1671
 1672
 1673
 1674
 1675
 1676
 1677
 1678
 1679
 1680
 1681
 1682
 1683
 1684
 1685
 1686
 1687
 1688
 1689
 1690
 1691
 1692
 1693
 1694
 1695
 1696
 1697
 1698
 1699
 1700
 1701
 1702
 1703
 1704
 1705
 1706
 1707
 1708
 1709
 1710
 1711
 1712
 1713
 1714
 1715
 1716
 1717
 1718
 1719
 1720
 1721
 1722
 1723
 1724
 1725
 1726
 1727
 1728
 1729
 1730
 1731
 1732
 1733
 1734
 1735
 1736
 1737
 1738
 1739
 1740
 1741
 1742
 1743
 1744
 1745
 1746
 1747
 1748
 1749
 1750
 1751
 1752
 1753
 1754
 1755
 1756
 1757
 1758
 1759
 1760
 1761
 1762
 1763
 1764
 1765
 1766
 1767
 1768
 1769
 1770
 1771
 1772
 1773
 1774
 1775
 1776
 1777
 1778
 1779
 1780
 1781
 1782
 1783
 1784
 1785
 1786
 1787
 1788
 1789
 1790
 1791
 1792
 1793
 1794
 1795
 1796
 1797
 1798
 1799
 1800
 1801
 1802
 1803
 1804
 1805
 1806
 1807
 1808
 1809
 1810
 1811
 1812
 1813
 1814
 1815
 1816
 1817
 1818
 1819
 1820
 1821
 1822
 1823
 1824
 1825
 1826
 1827
 1828
 1829
 1830
 1831
 1832
 1833
 1834
 1835
 1836
 1837
 1838
 1839
 1840
 1841
 1842
 1843
 1844
 1845
 1846
 1847
 1848
 1849
 1850
 1851
 1852
 1853
 1854
 1855
 1856
 1857
 1858
 1859
 1860
 1861
 1862
 1863
 1864
 1865
 1866
 1867
 1868
 1869
 1870
 1871
 1872
 1873
 1874
 1875
 1876
 1877
 1878
 1879
 1880
 1881
 1882
 1883
 1884
 1885
 1886
 1887
 1888
 1889
 1890
 1891
 1892
 1893
 1894
 1895
 1896
 1897
 1898
 1899
 1900
 1901
 1902
 1903
 1904
 1905
 1906
 1907
 1908
 1909
 1910
 1911
 1912
 1913
 1914
 1915
 1916
 1917
 1918
 1919
 1920
 1921
 1922
 1923
 1924
 1925
 1926
 1927
 1928
 1929
 1930
 1931
 1932
 1933
 1934
 1935
 1936
 1937
 1938
 1939
 1940
 1941
 1942
 1943
 1944
 1945
 1946
 1947
 1948
 1949
 1950
 1951
 1952
 1953
 1954
 1955
 1956
 1957
 1958
 1959
 1960
 1961
 1962
 1963
 1964
 1965
 1966
 1967
 1968
 1969
 1970
 1971
 1972
 1973
 1974
 1975
 1976
 1977
 1978
 1979
 1980
 1981
 1982
 1983
 1984
 1985
 1986
 1987
 1988
 1989
 1990
 1991
 1992
 1993
 1994
 1995
 1996
 1997
 1998
 1999
 2000
 2001
 2002
 2003
 2004
 2005
 2006
 2007
 2008
 2009
 2010
 2011
 2012
 2013
 2014
 2015
 2016
 2017
 2018
 2019
 2020
 2021
 2022
 2023
 2024
 2025
 2026
 2027
 2028
 2029
 2030
 2031
 2032
 2033
 2034
 2035
 2036
 2037
 2038
 2039
 2040
 2041
 2042
 2043
 2044
 2045
 2046
 2047
 2048
 2049
 2050
 2051
 2052
 2053
 2054
 2055
 2056
 2057
 2058
 2059
 2060
 2061
 2062
 2063
 2064
 2065
 2066
 2067
 2068
 2069
 2070
 2071
 2072
 2073
 2074
 2075
 2076
 2077
 2078
 2079
 2080
 2081
 2082
 2083
 2084
 2085
 2086
 2087
 2088
 2089
 2090
 2091
 2092
 2093
 2094
 2095
 2096
 2097
 2098
 2099
 2100
 2101
 2102
 2103
 2104
 2105
 2106
 2107
 2108
 2109
 2110
 2111
 2112
 2113
 2114
 2115
 2116
 2117
 2118
 2119
 2120
 2121
 2122
 2123
 2124
 2125
 2126
 2127
 2128
 2129
 2130
 2131
 2132
 2133
 2134
 2135
 2136
 2137
 2138
 2139
 2140
 2141
 2142
 2143
 2144
 2145
 2146
 2147
 2148
 2149
 2150
 2151
 2152
 2153
 2154
 2155
 2156
 2157
 2158
 2159
 2160
 2161
 2162
 2163
 2164
 2165
 2166
 2167
 2168
 2169
 2170
 2171
 2172
 2173
 2174
 2175
 2176
 2177
 2178
 2179
 2180
 2181
 2182
 2183
 2184
 2185
 2186
 2187
 2188
 2189
 2190
 2191
 2192
 2193
 2194
 2195
 2196
 2197
 2198
 2199
 2200
 2201
 2202
 2203
 2204
 2205
 2206
 2207
 2208
 2209
 2210
 2211
 2212
 2213
 2214
 2215
 2216
 2217
 2218
 2219
 2220
 2221
 2222
 2223
 2224
 2225
 2226
 2227
 2228
 2229
 2230
 2231
 2232
 2233
 2234
 2235
 2236
 2237
 2238
 2239
 2240
 2241
 2242
 2243
 2244
 2245
 2246
 2247
 2248
 2249
 2250
 2251
 2252
 2253
 2254
 2255
 2256
 2257
 2258
 2259
 2260
 2261
 2262
 2263
 2264
 2265
 2266
 2267
 2268
 2269
 2270
 2271
 2272
 2273
 2274
 2275
 2276
 2277
 2278
 2279
 2280
 2281
 2282
 2283
 2284
 2285
 2286
 2287
 2288
 2289
 2290
 2291
 2292
 2293
 2294
 2295
 2296
 2297
 2298
 2299
 2300
 2301
 2302
 2303
 2304
 2305
 2306
 2307
 2308
 2309
 2310
 2311
 2312
 2313
 2314
 2315
 2316
 2317
 2318
 2319
 2320
 2321
 2322
 2323
 2324
 2325
 2326
 2327
 2328
 2329
 2330
 2331
 2332
 2333
 2334
 2335
 2336
 2337
 2338
 2339
 2340
 2341
 2342
 2343
 2344
 2345
 2346
 2347
 2348
 2349
 2350
 2351
 2352
 2353
 2354
 2355
 2356
 2357
 2358
 2359
 2360
 2361
 2362
 2363
 2364
 2365
 2366
 2367
 2368
 2369
 2370
 2371
 2372
 2373
 2374
 2375
 2376
 2377
 2378
 2379
 2380
 2381
 2382
 2383
 2384
 2385
 2386
 2387
 2388
 2389
 2390
 2391
 2392
 2393
 2394
 2395
 2396
 2397
 2398
 2399
 2400
 2401
 2402
 2403
 2404
 2405
 2406
 2407
 2408
 2409
 2410
 2411
 2412
 2413
 2414
 2415
 2416
 2417
 2418
 2419
 2420
 2421
 2422
 2423
 2424
 2425
 2426
 2427
 2428
 2429
 2430
 2431
 2432
 2433
 2434
 2435
 2436
 2437
 2438
 2439
 2440
 2441
 2442
 2443
 2444
 2445
 2446
 2447
 2448
 2449
 2450
 2451
 2452
 2453
 2454
 2455
 2456
 2457
 2458
 2459
 2460
 2461
 2462
 2463
 2464
 2465
 2466
 2467
 2468
 2469
 2470
 2471
 2472
 2473
 2474
 2475
 2476
 2477
 2478
 2479
 2480
 2481
 2482
 2483
 2484
 2485
 2486
 2487
 2488
 2489
 2490
 2491
 2492
 2493
 2494
 2495
 2496
 2497
 2498
 2499
 2500
 2501
 2502
 2503
 2504
 2505
 2506
 2507
 2508
 2509
 2510
 2511
 2512
 2513
 2514
 2515
 2516
 2517
 2518
 2519
 2520
 2521
 2522
 2523
 2524
 2525
 2526
 2527
 2528
 2529
 2530
 2531
 2532
 2533
 2534
 2535
 2536
 2537
 2538
 2539
 2540
 2541
 2542
 2543
 2544
 2545
 2546
 2547
 2548
 2549
 2550
 2551
 2552
 2553
 2554
 2555
 2556
 2557
 2558
 2559
 2560
 2561
 2562
 2563
 2564
 2565
 2566
 2567
 2568
 2569
 2570
 2571
 2572
 2573
 2574
 2575
 2576
 2577
 2578
 2579
 2580
 2581
 2582
 2583
 2584
 2585
 2586
 2587
 2588
 2589
 2590
 2591
 2592
 2593
 2594
 2595
 2596
 2597
 2598
 2599
 2600
 2601
 2602
 2603
 2604
 2605
 2606
 2607
 2608
 2609
 2610
 2611
 2612
 2613
 2614
 2615
 2616
 2617
 2618
 2619
 2620
 2621
 2622
 2623
 2624
 2625
 2626
 2627
 2628
 2629
 2630
 2631
 2632
 2633
 2634
 2635
 2636
 2637
 2638
 2639
 2640
 2641
 2642
 2643
 2644
 2645
 2646
 2647
 2648
 2649
 2650
 2651
 2652
 2653
 2654
 2655
 2656
 2657
 2658
 2659
 2660
 2661
 2662
 2663
 2664
 2665
 2666
 2667
 2668
 2669
 2670
 2671
 2672
 2673
 2674
 2675
 2676
 2677
 2678
 2679
 2680
 2681
 2682
 2683
 2684
 2685
 2686
 2687
 2688
 2689
 2690
 2691
 2692
 2693
 2694
 2695
 2696
 2697
 2698
 2699
 2700
 2701
 2702
 2703
 2704
 2705
 2706
 2707
 2708
 2709
 2710
 2711
 2712
 2713
 2714
 2715
 2716
 2717
 2718
 2719
 2720
 2721
 2722
 2723
 2724
 2725
 2726
 2727
 2728
 2729
 2730
 2731
 2732
 2733
 2734
 2735
 2736
 2737
 2738
 2739
 2740
 2741
 2742
 2743
 2744
 2745
 2746
 2747
 2748
 2749
 2750
 2751
 2752
 2753
 2754
 2755
 2756
 2757
 2758
 2759
 2760
 2761
 2762
 2763
 2764
 2765
 2766
 2767
 2768
 2769
 2770
 2771
 2772
 2773
 2774
 2775
 2776
 2777
 2778
 2779
 2780
 2781
 2782
 2783
 2784
 2785
 2786
 2787
 2788
 2789
 2790
 2791
 2792
 2793
 2794
 2795
 2796
 2797
 2798
 2799
 2800
 2801
 2802
 2803
 2804
 2805
 2806
 2807
 2808
 2809
 2810
 2811
 2812
 2813
 2814
 2815
 2816
 2817
 2818
 2819
 2820
 2821
 2822
 2823
 2824
 2825
 2826
 2827
 2828
 2829
 2830
 2831
 2832
 2833
 2834
 2835
 2836
 2837
 2838
 2839
 2840
 2841
 2842
 2843
 2844
 2845
 2846
 2847
 2848
 2849
 2850
 2851
 2852
 2853
 2854
 2855
 2856
 2857
 2858
 2859
 2860
 2861
 2862
 2863
 2864
 2865
 2866
 2867
 2868
 2869
 2870
 2871
 2872
 2873
 2874
 2875
 2876
 2877
 2878
 2879
 2880
 2881
 2882
 2883
 2884
 2885
 2886
 2887
 2888
 2889
 2890
 2891
 2892
 2893
 2894
 2895
 2896
 2897
 2898
 2899
 2900
 2901
 2902
 2903
 2904
 2905
 2906
 2907
 2908
 2909
 2910
 2911
 2912
 2913
 2914
 2915
 2916
 2917
 2918
 2919
 2920
 2921
 2922
 2923
 2924
 2925
 2926
 2927
 2928
 2929
 2930
 2931
 2932
 2933
 2934
 2935
 2936
 2937
 2938
 2939
 2940
 2941
 2942
 2943
 2944
 2945
 2946
 2947
 2948
 2949
 2950
 2951
 2952
 2953
 2954
 2955
 2956
 2957
 2958
 2959
 2960
 2961
 2962
 2963
 2964
 2965
 2966
 2967
 2968
 2969
 2970
 2971
 2972
 2973
 2974
 2975
 2976
 2977
 2978
 2979
 2980
 2981
 2982
 2983
 2984
 2985
 2986
 2987
 2988
 2989
 2990
 2991
 2992
 2993
 2994
 2995
 2996
 2997
 2998
 2999
 3000
 3001
 3002
 3003
 3004
 3005
 3006
 3007
 3008
 3009
 3010
 3011
 3012
 3013
 3014
 3015
 3016
 3017
 3018
 3019
 3020
 3021
 3022
 3023
 3024
 3025
 3026
 3027
 3028
 3029
 3030
 3031
 3032
 3033
 3034
 3035
 3036
 3037
 3038
 3039
 3040
 3041
 3042
 3043
 3044
 3045
 3046
 3047
 3048
 3049
 3050
 3051
 3052
 3053
 3054
 3055
 3056
 3057
 3058
 3059
 3060
 3061
 3062
 3063
 3064
 3065
 3066
 3067
 3068
 3069
 3070
 3071
 3072
 3073
 3074
 3075
 3076
 3077
 3078
 3079
 3080
 3081
 3082
 3083
 3084
 3085
 3086
 3087
 3088
 3089
 3090
 3091
 3092
 3093
 3094
 3095
 3096
 3097
 3098
 3099
 3100
 3101
 3102
 3103
 3104
 3105
 3106
 3107
 3108
 3109
 3110
 3111
 3112
 3113
 3114
 3115
 3116
 3117
 3118
 3119
 3120
 3121
 3122
 3123
 3124
 3125
 3126
 3127
 3128
 3129
 3130
 3131
 3132
 3133
 3134
 3135
 3136
 3137
 3138
 3139
 3140
 3141
 3142
 3143
 3144
 3145
 3146
 3147
 3148
 3149
 3150
 3151
 3152
 3153
 3154
 3155
 3156
 3157
 3158
 3159
 3160
 3161
 3162
 3163
 3164
 3165
 3166
 3167
 3168
 3169
 3170
 3171
 3172
 3173
 3174
 3175
 3176
 3177
 3178
 3179
 3180
 3181
 3182
 3183
 3184
 3185
 3186
 3187
 3188
 3189
 3190
 3191
 3192
 3193
 3194
 3195
 3196
 3197
 3198
 3199
 3200
 3201
 3202
 3203
 3204
 3205
 3206
 3207
 3208
 3209
 3210
 3211
 3212
 3213
 3214
 3215
 3216
 3217
 3218
 3219
 3220
 3221
 3222
 3223
 3224
 3225
 3226
 3227
 3228
 3229
 3230
 3231
 3232
 3233
 3234
 3235
 3236
 3237
 3238
 3239
 3240
 3241
 3242
 3243
 3244
 3245
 3246
 3247
 3248
 3249
 3250
 3251
 3252
 3253
 3254
 3255
 3256
 3257
 3258
 3259
 3260
 3261
 3262
 3263
 3264
 3265
 3266
 3267
 3268
 3269
 3270
 3271
 3272
 3273
 3274
 3275
 3276
 3277
 3278
 3279
 3280
 3281
 3282
 3283
 3284
 3285
 3286
 3287
 3288
 3289
 3290
 3291
 3292
 3293
 3294
 3295
 3296
 3297
 3298
 3299
 3300
 3301
 3302
 3303
 3304
 3305
 3306
 3307
 3308
 3309
 3310
 3311
 3312
 3313
 3314
 3315
 3316
 3317
 3318
 3319
 3320
 3321
 3322
 3323
 3324
 3325
 3326
 3327
 3328
 3329
 3330
 3331
 3332
 3333
 3334
 3335
 3336
 3337
 3338
 3339
 3340
 3341
 3342
 3343
 3344
 3345
 3346
 3347
 3348
 3349
 3350
 3351
 3352
 3353
 3354
 3355
 3356
 3357
 3358
 3359
 3360
 3361
 3362
 3363
 3364
 3365
 3366
 3367
 3368
 3369
 3370
 3371
 3372
 3373
 3374
 3375
 3376
 3377
 3378
 3379
 3380
 3381
 3382
 3383
 3384
 3385
 3386
 3387
 3388
 3389
 3390
 3391
 3392
 3393
 3394
 3395
 3396
 3397
 3398
 3399
 3400
 3401
 3402
 3403
 3404
 3405
 3406
 3407
 3408
 3409
 3410
 3411
 3412
 3413
 3414
 3415
 3416
 3417
 3418
 3419
 3420
 3421
 3422
 3423
 3424
 3425
 3426
 3427
 3428
 3429
 3430
 3431
 3432
 3433
 3434
 3435
 3436
 3437
 3438
 3439
 3440
 3441
 3442
 3443
 3444
 3445
 3446
 3447
 3448
 3449
 3450
 3451
 3452
 3453
 3454
 3455
 3456
 3457
 3458
 3459
 3460
 3461
 3462
 3463
 3464
 3465
 3466
 3467
 3468
 3469
 3470
 3471
 3472
 3473
 3474
 3475
 3476
 3477
 3478
 3479
 3480
 3481
 3482
 3483
 3484
 3485
 3486
 3487
 3488
 3489
 3490
 3491
 3492
 3493
 3494
 3495
 3496
 3497
 3498
 3499
 3500
 3501
 3502
 3503
 3504
 3505
 3506
 3507
 3508
 3509
 3510
 3511
 3512
 3513
 3514
 3515
 3516
 3517
 3518
 3519
 3520
 3521
 3522
 3523
 3524
 3525
 3526
 3527
 3528
 3529
 3530
 3531
 3532
 3533
 3534
 3535
 3536
 3537
 3538
 3539
 3540
 3541
 3542
 3543
 3544
 3545
 3546
 3547
 3548
 3549
 3550
 3551
 3552
 3553
 3554
 3555
 3556
 3557
 3558
 3559
 3560
 3561
 3562
 3563
 3564
 3565
 3566
 3567
 3568
 3569
 3570
 3571
 3572
 3573
 3574
 3575
 3576
 3577
 3578
 3579
 3580
 3581
 3582
 3583
 3584
 3585
 3586
 3587
 3588
 3589
 3590
 3591
 3592
 3593
 3594
 3595
 3596
 3597
 3598
 3599
 3600
 3601
 3602
 3603
 3604
 3605
 3606
 3607
 3608
 3609
 3610
 3611
 3612
 3613
 3614
 3615
 3616
 3617
 3618
 3619
 3620
 3621
 3622
 3623
 3624
 3625
 3626
 3627
 3628
 3629
 3630
 3631
 3632
 3633
 3634
 3635
 3636
 3637
 3638
 3639
 3640
 3641
 3642
 3643
 3644
 3645
 3646
 3647
 3648
 3649
 3650
 3651
 3652
 3653
 3654
 3655
 3656
 3657
 3658
 3659
 3660
 3661
 3662
 3663
 3664
 3665
 3666
 3667
 3668
 3669
 3670
 3671
 3672
 3673
 3674
 3675
 3676
 3677
 3678
 3679
 3680
 3681
 3682
 3683
 3684
 3685
 3686
 3687
 3688
 3689
 3690
 3691
 3692
 3693
 3694
 3695
 3696
 3697
 3698
 3699
 3700
 3701
 3702
 3703
 3704
 3705
 3706
 3707
 3708
 3709
 3710
 3711
 3712
 3713
 3714
 3715
 3716
 3717
 3718
 3719
 3720
 3721
 3722
 3723
 3724
 3725
 3726
 3727
 3728
 3729
 3730
 3731
 3732
 3733
 3734
 3735
 3736
 3737
 3738
 3739
 3740
 3741
 3742
 3743
 3744
 3745
 3746
 3747
 3748
 3749
 3750
 3751
 3752
 3753
 3754
 3755
 3756
 3757
 3758
 3759
 3760
 3761
 3762
 3763
 3764
 3765
 3766
 3767
 3768
 3769
 3770
 3771
 3772
 3773
 3774
 3775
 3776
 3777
 3778
 3779
 3780
 3781
 3782
 3783
 3784
 3785
 3786
 3787
 3788
 3789
 3790
 3791
 3792
 3793
 3794
 3795
 3796
 3797
 3798
 3799
 3800
 3801
 3802
 3803
 3804
 3805
 3806
 3807
 3808
 3809
 3810
 3811
 3812
 3813
 3814
 3815
 3816
 3817
 3818
 3819
 3820
 3821
 3822
 3823
 3824
 3825
 3826
 3827
 3828
 3829
 3830
 3831
 3832
 3833
 3834
 3835
 3836
 3837
 3838
 3839
 3840
 3841
 3842
 3843
 3844
 3845
 3846
 3847
 3848
 3849
 3850
 3851
 3852
 3853
 3854
 3855
 3856
 3857
 3858
 3859
 3860
 3861
 3862
 3863
 3864
 3865
 3866
 3867
 3868
 3869
 3870
 3871
 3872
 3873
 3874
 3875
 3876
 3877
 3878
 3879
 3880
 3881
 3882
 3883
 3884
 3885
 3886
 3887
 3888
 3889
 3890
 3891
 3892
 3893
 3894
 3895
 3896
 3897
 3898
 3899
 3900
 3901
 3902
 3903
 3904
 3905
 3906
 3907
 3908
 3909
 3910
 3911
 3912
 3913
 3914
 3915
 3916
 3917
 3918
 3919
 3920
 3921
 3922
 3923
 3924
 3925
 3926
 3927
 3928
 3929
 3930
 3931
 3932
 3933
 3934
 3935
 3936
 3937
 3938
 3939
 3940
 3941
 3942
 3943
 3944
 3945
 3946
 3947
 3948
 3949
 3950
 3951
 3952
 3953
 3954
 3955
 3956
 3957
 3958
 3959
 3960
 3961
 3962
 3963
 3964
 3965
 3966
 3967
 3968
 3969
 3970
 3971
 3972
 3973
 3974
 3975
 3976
 3977
 3978
 3979
 3980
 3981
 3982
 3983
 3984
 3985
 3986
 3987
 3988
 3989
 3990
 3991
 3992
 3993
 3994
 3995
 3996
 3997
 3998
 3999
 4000
 4001
 4002
 4003
 4004
 4005
 4006
 4007
 4008
 4009
 4010
 4011
 4012
 4013
 4014
 4015
 4016
 4017
 4018
 4019
 4020
 4021
 4022
 4023
 4024
 4025
 4026
 4027
 4028
 4029
 4030
 4031
 4032
 4033
 4034
 4035
 4036
 4037
 4038
 4039
 4040
 4041
 4042
 4043
 4044
 4045
 4046
 4047
 4048
 4049
 4050
 4051
 4052
 4053
 4054
 4055
 4056
 4057
 4058
 4059
 4060
 4061
 4062
 4063
 4064
 4065
 4066
 4067
 4068
 4069
 4070
 4071
 4072
 4073
 4074
 4075
 4076
 4077
 4078
 4079
 4080
 4081
 4082
 4083
 4084
 4085
 4086
 4087
 4088
 4089
 4090
 4091
 4092
 4093
 4094
 4095
 4096
 4097
 4098
 4099
 4100
 4101
 4102
 4103
 4104
 4105
 4106
 4107
 4108
 4109
 4110
 4111
 4112
 4113
 4114
 4115
 4116
 4117
 4118
 4119
 4120
 4121
 4122
 4123
 4124
 4125
 4126
 4127
 4128
 4129
 4130
 4131
 4132
 4133
 4134
 4135
 4136
 4137
 4138
 4139
 4140
 4141
 4142
 4143
 4144
 4145
 4146
 4147
 4148
 4149
 4150
 4151
 4152
 4153
 4154
 4155
 4156
 4157
 4158
 4159
 4160
 4161
 4162
 4163
 4164
 4165
 4166
 4167
 4168
 4169
 4170
 4171
 4172
 4173
 4174
 4175
 4176
 4177
 4178
 4179
 4180
 4181
 4182
 4183
 4184
 4185
 4186
 4187
 4188
 4189
 4190
 4191
 4192
 4193
 4194
 4195
 4196
 4197
 4198
 4199
 4200
 4201
 4202
 4203
 4204
 4205
 4206
 4207
 4208
 4209
 4210
 4211
 4212
 4213
 4214
 4215
 4216
 4217
 4218
 4219
 4220
 4221
 4222
 4223
 4224
 4225
 4226
 4227
 4228
 4229
 4230
 4231
 4232
 4233
 4234
 4235
 4236
 4237
 4238
 4239
 4240
 4241
 4242
 4243
 4244
 4245
 4246
 4247
 4248
 4249
 4250
 4251
 4252
 4253
 4254
 4255
 4256
 4257
 4258
 4259
 4260
 4261
 4262
 4263
 4264
 4265
 4266
 4267
 4268
 4269
 4270
 4271
 4272
 4273
 4274
 4275
 4276
 4277
 4278
 4279
 4280
 4281
 4282
 4283
 4284
 4285
 4286
 4287
 4288
 4289
 4290
 4291
 4292
 4293
 4294
 4295
 4296
 4297
 4298
 4299
 4300
 4301
 4302
 4303
 4304
 4305
 4306
 4307
 4308
 4309
 4310
 4311
 4312
 4313
 4314
 4315
 4316
 4317
 4318
 4319
 4320
 4321
 4322
 4323
 4324
 4325
 4326
 4327
 4328
 4329
 4330
 4331
 4332
 4333
 4334
 4335
 4336
 4337
 4338
 4339
 4340
 4341
 4342
 4343
 4344
 4345
 4346
 4347
 4348
 4349
 4350
 4351
 4352
 4353
 4354
 4355
 4356
 4357
 4358
 4359
 4360
 4361
 4362
 4363
 4364
 4365
 4366
 4367
 4368
 4369
 4370
 4371
 4372
 4373
 4374
 4375
 4376
 4377
 4378
 4379
 4380
 4381
 4382
 4383
 4384
 4385
 4386
 4387
 4388
 4389
 4390
 4391
 4392
 4393
 4394
 4395
 4396
 4397
 4398
 4399
 4400
 4401
 4402
 4403
 4404
 4405
 4406
 4407
 4408
 4409
 4410
 4411
 4412
 4413
 4414
 4415
 4416
 4417
 4418
 4419
 4420
 4421
 4422
 4423
 4424
 4425
 4426
 4427
 4428
 4429
 4430
 4431
 4432
 4433
 4434
 4435
 4436
 4437
 4438
 4439
 4440
 4441
 4442
 4443
 4444
 4445
 4446
 4447
 4448
 4449
 4450
 4451
 4452
 4453
 4454
 4455
 4456
 4457
 4458
 4459
 4460
 4461
 4462
 4463
 4464
 4465
 4466
 4467
 4468
 4469
 4470
 4471
 4472
 4473
 4474
 4475
 4476
 4477
 4478
 4479
 4480
 4481
 4482
 4483
 4484
 4485
 4486
 4487
 4488
 4489
 4490
 4491
 4492
 4493
 4494
 4495
 4496
 4497
 4498
 4499
 4500
 4501
 4502
 4503
 4504
 4505
 4506
 4507
 4508
 4509
 4510
 4511
 4512
 4513
 4514
 4515
 4516
 4517
 4518
 4519
 4520
 4521
 4522
 4523
 4524
 4525
 4526
 4527
 4528
 4529
 4530
 4531
 4532
 4533
 4534
 4535
 4536
 4537
 4538
 4539
 4540
 4541
 4542
 4543
 4544
 4545
 4546
 4547
 4548
 4549
 4550
 4551
 4552
 4553
 4554
 4555
 4556
 4557
 4558
 4559
 4560
 4561
 4562
 4563
 4564
 4565
 4566
 4567
 4568
 4569
 4570
 4571
 4572
 4573
 4574
 4575
 4576
 4577
 4578
 4579
 4580
 4581
 4582
 4583
 4584
 4585
 4586
 4587
 4588
 4589
 4590
 4591
 4592
 4593
 4594
 4595
 4596
 4597
 4598
 4599
 4600
 4601
 4602
 4603
 4604
 4605
 4606
 4607
 4608
 4609
 4610
 4611
 4612
 4613
 4614
 4615
 4616
 4617
 4618
 4619
 4620
 4621
 4622
 4623
 4624
 4625
 4626
 4627
 4628
 4629
 4630
 4631
 4632
 4633
 4634
 4635
 4636
 4637
 4638
 4639
 4640
 4641
 4642
 4643
 4644
 4645
 4646
 4647
 4648
 4649
 4650
 4651
 4652
 4653
 4654
 4655
 4656
 4657
 4658
 4659
 4660
 4661
 4662
 4663
 4664
 4665
 4666
 4667
 4668
 4669
 4670
 4671
 4672
 4673
 4674
 4675
 4676
 4677
 4678
 4679
 4680
 4681
 4682
 4683
 4684
 4685
 4686
 4687
 4688
 4689
 4690
 4691
 4692
 4693
 4694
 4695
 4696
 4697
 4698
 4699
 4700
 4701
 4702
 4703
 4704
 4705
 4706
 4707
 4708
 4709
 4710
 4711
 4712
 4713
 4714
 4715
 4716
 4717
 4718
 4719
 4720
 4721
 4722
 4723
 4724
 4725
 4726
 4727
 4728
 4729
 4730
 4731
 4732
 4733
 4734
 4735
 4736
 4737
 4738
 4739
 4740
 4741
 4742
 4743
 4744
 4745
 4746
 4747
 4748
 4749
 4750
 4751
 4752
 4753
 4754
 4755
 4756
 4757
 4758
 4759
 4760
 4761
 4762
 4763
 4764
 4765
 4766
 4767
 4768
 4769
 4770
 4771
 4772
 4773
 4774
 4775
 4776
 4777
 4778
 4779
 4780
 4781
 4782
 4783
 4784
 4785
 4786
 4787
 4788
 4789
 4790
 4791
 4792
 4793
 4794
 4795
 4796
 4797
 4798
 4799
 4800
 4801
 4802
 4803
 4804
 4805
 4806
 4807
 4808
 4809
 4810
 4811
 4812
 4813
 4814
 4815
 4816
 4817
 4818
 4819
 4820
 4821
 4822
 4823
 4824
 4825
 4826
 4827
 4828
 4829
 4830
 4831
 4832
 4833
 4834
 4835
 4836
 4837
 4838
 4839
 4840
 4841
 4842
 4843
 4844
 4845
 4846
 4847
 4848
 4849
 4850
 4851
 4852
 4853
 4854
 4855
 4856
 4857
 4858
 4859
 4860
 4861
 4862
 4863
 4864
 4865
 4866
 4867
 4868
 4869
 4870
 4871
 4872
 4873
 4874
 4875
 4876
 4877
 4878
 4879
 4880
 4881
 4882
 4883
 4884
 4885
 4886
 4887
 4888
 4889
 4890
 4891
 4892
 4893
 4894
 4895
 4896
 4897
 4898
 4899
 4900
 4901
 4902
 4903
 4904
 4905
 4906
 4907
 4908
 4909
 4910
 4911
 4912
 4913
 4914
 4915
 4916
 4917
 4918
 4919
 4920
 4921
 4922
 4923
 4924
 4925
 4926
 4927
 4928
 4929
 4930
 4931
 4932
 4933
 4934
 4935
 4936
 4937
 4938
 4939
 4940
 4941
 4942
 4943
 4944
 4945
 4946
 4947
 4948
 4949
 4950
 4951
 4952
 4953
 4954
 4955
 4956
 4957
 4958
 4959
 4960
 4961
 4962
 4963
 4964
 4965
 4966
 4967
 4968
 4969
 4970
 4971
 4972
 4973
 4974
 4975
 4976
 4977
 4978
 4979
 4980
 4981
 4982
 4983
 4984
 4985
 4986
 4987
 4988
 4989
 4990
 4991
 4992
 4993
 4994
 4995
 4996
 4997
 4998
 4999
 5000
 5001
 5002
 5003
 5004
 5005
 5006
 5007
 5008
 5009
 5010
 5011
 5012
 5013
 5014
 5015
 5016
 5017
 5018
 5019
 5020
 5021
 5022
 5023
 5024
 5025
 5026
 5027
 5028
 5029
 5030
 5031
 5032
 5033
 5034
 5035
 5036
 5037
 5038
 5039
 5040
 5041
 5042
 5043
 5044
 5045
 5046
 5047
 5048
 5049
 5050
 5051
 5052
 5053
 5054
 5055
 5056
 5057
 5058
 5059
 5060
 5061
 5062
 5063
 5064
 5065
 5066
 5067
 5068
 5069
 5070
 5071
 5072
 5073
 5074
 5075
 5076
 5077
 5078
 5079
 5080
 5081
 5082
 5083
 5084
 5085
 5086
 5087
 5088
 5089
 5090
 5091
 5092
 5093
 5094
 5095
 5096
 5097
 5098
 5099
 5100
 5101
 5102
 5103
 5104
 5105
 5106
 5107
 5108
 5109
 5110
 5111
 5112
 5113
 5114
 5115
 5116
 5117
 5118
 5119
 5120
 5121
 5122
 5123
 5124
 5125
 5126
 5127
 5128
 5129
 5130
 5131
 5132
 5133
 5134
 5135
 5136
 5137
 5138
 5139
 5140
 5141
 5142
 5143
 5144
 5145
 5146
 5147
 5148
 5149
 5150
 5151
 5152
 5153
 5154
 5155
 5156
 5157
 5158
 5159
 5160
 5161
 5162
 5163
 5164
 5165
 5166
 5167
 5168
 5169
 5170
 5171
 5172
 5173
 5174
 5175
 5176
 5177
 5178
 5179
 5180
 5181
 5182
 5183
 5184
 5185
 5186
 5187
 5188
 5189
 5190
 5191
 5192
 5193
 5194
 5195
 5196
 5197
 5198
 5199
 5200
 5201
 5202
 5203
 5204
 5205
 5206
 5207
 5208
 5209
 5210
 5211
 5212
 5213
 5214
 5215
 5216
 5217
 5218
 5219
 5220
 5221
 5222
 5223
 5224
 5225
 5226
 5227
 5228
 5229
 5230
 5231
 5232
 5233
 5234
 5235
 5236
 5237
 5238
 5239
 5240
 5241
 5242
 5243
 5244
 5245
 5246
 5247
 5248
 5249
 5250
 5251
 5252
 5253
 5254
 5255
 5256
 5257
 5258
 5259
 5260
 5261
 5262
 5263
 5264
 5265
 5266
 5267
 5268
 5269
 5270
 5271
 5272
 5273
 5274
 5275
 5276
 5277
 5278
 5279
 5280
 5281
 5282
 5283
 5284
 5285
 5286
 5287
 5288
 5289
 5290
 5291
 5292
 5293
 5294
 5295
 5296
 5297
 5298
 5299
 5300
 5301
 5302
 5303
 5304
 5305
 5306
 5307
 5308
 5309
 5310
 5311
 5312
 5313
 5314
 5315
 5316
 5317
 5318
 5319
 5320
 5321
 5322
 5323
 5324
 5325
 5326
 5327
 5328
 5329
 5330
 5331
 5332
 5333
 5334
 5335
 5336
 5337
 5338
 5339
 5340
 5341
 5342
 5343
 5344
 5345
 5346
 5347
 5348
 5349
 5350
 5351
 5352
 5353
 5354
 5355
 5356
 5357
 5358
 5359
 5360
 5361
 5362
 5363
 5364
 5365
 5366
 5367
 5368
 5369
 5370
 5371
 5372
 5373
 5374
 5375
 5376
 5377
 5378
 5379
 5380
 5381
 5382
 5383
 5384
 5385
 5386
 5387
 5388
 5389
 5390
 5391
 5392
 5393
 5394
 5395
 5396
 5397
 5398
 5399
 5400
 5401
 5402
 5403
 5404
 5405
 5406
 5407
 5408
 5409
 5410
 5411
 5412
 5413
 5414
 5415
 5416
 5417
 5418
 5419
 5420
 5421
 5422
 5423
 5424
 5425
 5426
 5427
 5428
 5429
 5430
 5431
 5432
 5433
 5434
 5435
 5436
 5437
 5438
 5439
 5440
 5441
 5442
 5443
 5444
 5445
 5446
 5447
 5448
 5449
 5450
 5451
 5452
 5453
 5454
 5455
 5456
 5457
 5458
 5459
 5460
 5461
 5462
 5463
 5464
 5465
 5466
 5467
 5468
 5469
 5470
 5471
 5472
 5473
 5474
 5475
 5476
 5477
 5478
 5479
 5480
 5481
 5482
 5483
 5484
 5485
 5486
 5487
 5488
 5489
 5490
 5491
 5492
 5493
 5494
 5495
 5496
 5497
 5498
 5499
 5500
 5501
 5502
 5503
 5504
 5505
 5506
 5507
 5508
 5509
 5510
 5511
 5512
 5513
 5514
 5515
 5516
 5517
 5518
 5519
 5520
 5521
 5522
 5523
 5524
 5525
 5526
 5527
 5528
 5529
 5530
 5531
 5532
 5533
 5534
 5535
 5536
 5537
 5538
 5539
 5540
 5541
 5542
 5543
 5544
 5545
 5546
 5547
 5548
 5549
 5550
 5551
 5552
 5553
 5554
 5555
 5556
 5557
 5558
 5559
 5560
 5561
 5562
 5563
 5564
 5565
 5566
 5567
 5568
 5569
 5570
 5571
 5572
 5573
 5574
 5575
 5576
 5577
 5578
 5579
 5580
 5581
 5582
 5583
 5584
 5585
 5586
 5587
 5588
 5589
 5590
 5591
 5592
 5593
 5594
 5595
 5596
 5597
 5598
 5599
 5600
 5601
 5602
 5603
 5604
 5605
 5606
 5607
 5608
 5609
 5610
 5611
 5612
 5613
 5614
 5615
 5616
 5617
 5618
 5619
 5620
 5621
 5622
 5623
 5624
 5625
 5626
 5627
 5628
 5629
 5630
 5631
 5632
 5633
 5634
 5635
 5636
 5637
 5638
 5639
 5640
 5641
 5642
 5643
 5644
 5645
 5646
 5647
 5648
 5649
 5650
 5651
 5652
 5653
 5654
 5655
 5656
 5657
 5658
 5659
 5660
 5661
 5662
 5663
 5664
 5665
 5666
 5667
 5668
 5669
 5670
 5671
 5672
 5673
 5674
 5675
 5676
 5677
 5678
 5679
 5680
 5681
 5682
 5683
 5684
 5685
 5686
 5687
 5688
 5689
 5690
 5691
 5692
 5693
 5694
 5695
 5696
 5697
 5698
 5699
 5700
 5701
 5702
 5703
 5704
 5705
 5706
 5707
 5708
 5709
 5710
 5711
 5712
 5713
 5714
 5715
 5716
 5717
 5718
 5719
 5720
 5721
 5722
 5723
 5724
 5725
 5726
 5727
 5728
 5729
 5730
 5731
 5732
 5733
 5734
 5735
 5736
 5737
 5738
 5739
 5740
 5741
 5742
 5743
 5744
 5745
 5746
 5747
 5748
 5749
 5750
 5751
 5752
 5753
 5754
 5755
 5756
 5757
 5758
 5759
 5760
 5761
 5762
 5763
 5764
 5765
 5766
 5767
 5768
 5769
 5770
 5771
 5772
 5773
 5774
 5775
 5776
 5777
 5778
 5779
 5780
 5781
 5782
 5783
 5784
 5785
 5786
 5787
 5788
 5789
 5790
 5791
 5792
 5793
 5794
 5795
 5796
 5797
 5798
 5799
 5800
 5801
 5802
 5803
 5804
 5805
 5806
 5807
 5808
 5809
 5810
 5811
 5812
 5813
 5814
 5815
 5816
 5817
 5818
 5819
 5820
 5821
 5822
 5823
 5824
 5825
 5826
 5827
 5828
 5829
 5830
 5831
 5832
 5833
 5834
 5835
 5836
 5837
 5838
 5839
 5840
 5841
 5842
 5843
 5844
 5845
 5846
 5847
 5848
 5849
 5850
 5851
 5852
 5853
 5854
 5855
 5856
 5857
 5858
 5859
 5860
 5861
 5862
 5863
 5864
 5865
 5866
 5867
 5868
 5869
 5870
 5871
 5872
 5873
 5874
 5875
 5876
 5877
 5878
 5879
 5880
 5881
 5882
 5883
 5884
 5885
 5886
 5887
 5888
 5889
 5890
 5891
 5892
 5893
 5894
 5895
 5896
 5897
 5898
 5899
 5900
 5901
 5902
 5903
 5904
 5905
 5906
 5907
 5908
 5909
 5910
 5911
 5912
 5913
 5914
 5915
 5916
 5917
 5918
 5919
 5920
 5921
 5922
 5923
 5924
 5925
 5926
 5927
 5928
 5929
 5930
 5931
 5932
 5933
 5934
 5935
 5936
 5937
 5938
 5939
 5940
 5941
 5942
 5943
 5944
 5945
 5946
 5947
 5948
 5949
 5950
 5951
 5952
 5953
 5954
 5955
 5956
 5957
 5958
 5959
 5960
 5961
 5962
 5963
 5964
 5965
 5966
 5967
 5968
 5969
 5970
 5971
 5972
 5973
 5974
 5975
 5976
 5977
 5978
 5979
 5980
 5981
 5982
 5983
 5984
 5985
 5986
 5987
 5988
 5989
 5990
 5991
 5992
 5993
 5994
 5995
 5996
 5997
 5998
 5999
 6000
 6001
 6002
 6003
 6004
 6005
 6006
 6007
 6008
 6009
 6010
 6011
 6012
 6013
 6014
 6015
 6016
 6017
 6018
 6019
 6020
 6021
 6022
 6023
 6024
 6025
 6026
 6027
 6028
 6029
 6030
 6031
 6032
 6033
 6034
 6035
 6036
 6037
 6038
 6039
 6040
 6041
 6042
 6043
 6044
 6045
 6046
 6047
 6048
 6049
 6050
 6051
 6052
 6053
 6054
 6055
 6056
 6057
 6058
 6059
 6060
 6061
 6062
 6063
 6064
 6065
 6066
 6067
 6068
 6069
 6070
 6071
 6072
 6073
 6074
 6075
 6076
 6077
 6078
 6079
 6080
 6081
 6082
 6083
 6084
 6085
 6086
 6087
 6088
 6089
 6090
 6091
 6092
 6093
 6094
 6095
 6096
 6097
 6098
 6099
 6100
 6101
 6102
 6103
 6104
 6105
 6106
 6107
 6108
 6109
 6110
 6111
 6112
 6113
 6114
 6115
 6116
 6117
 6118
 6119
 6120
 6121
 6122
 6123
 6124
 6125
 6126
 6127
 6128
 6129
 6130
 6131
 6132
 6133
 6134
 6135
 6136
 6137
 6138
 6139
 6140
 6141
 6142
 6143
 6144
 6145
 6146
 6147
 6148
 6149
 6150
 6151
 6152
 6153
 6154
 6155
 6156
 6157
 6158
 6159
 6160
 6161
 6162
 6163
 6164
 6165
 6166
 6167
 6168
 6169
 6170
 6171
 6172
 6173
 6174
 6175
 6176
 6177
 6178
 6179
 6180
 6181
 6182
 6183
 6184
 6185
 6186
 6187
 6188
 6189
 6190
 6191
 6192
 6193
 6194
 6195
 6196
 6197
 6198
 6199
 6200
 6201
 6202
 6203
 6204
 6205
 6206
 6207
 6208
 6209
 6210
 6211
 6212
 6213
 6214
 6215
 6216
 6217
 6218
 6219
 6220
 6221
 6222
 6223
 6224
 6225
 6226
 6227
 6228
 6229
 6230
 6231
 6232
 6233
 6234
 6235
 6236
 6237
 6238
 6239
 6240
 6241
 6242
 6243
 6244
 6245
 6246
 6247
 6248
 6249
 6250
 6251
 6252
 6253
 6254
 6255
 6256
 6257
 6258
 6259
 6260
 6261
 6262
 6263
 6264
 6265
 6266
 6267
 6268
 6269
 6270
 6271
 6272
 6273
 6274
 6275
 6276
 6277
 6278
 6279
 6280
 6281
 6282
 6283
 6284
 6285
 6286
 6287
 6288
 6289
 6290
 6291
 6292
 6293
 6294
 6295
 6296
 6297
 6298
 6299
 6300
 6301
 6302
 6303
 6304
 6305
 6306
 6307
 6308
 6309
 6310
 6311
 6312
 6313
 6314
 6315
 6316
 6317
 6318
 6319
 6320
 6321
 6322
 6323
 6324
 6325
 6326
 6327
 6328
 6329
 6330
 6331
 6332
 6333
 6334
 6335
 6336
 6337
 6338
 6339
 6340
 6341
 6342
 6343
 6344
 6345
 6346
 6347
 6348
 6349
 6350
 6351
 6352
 6353
 6354
 6355
 6356
 6357
 6358
 6359
 6360
 6361
 6362
 6363
 6364
 6365
 6366
 6367
 6368
 6369
 6370
 6371
 6372
 6373
 6374
 6375
 6376
 6377
 6378
 6379
 6380
 6381
 6382
 6383
 6384
 6385
 6386
 6387
 6388
 6389
 6390
 6391
 6392
 6393
 6394
 6395
 6396
 6397
 6398
 6399
 6400
 6401
 6402
 6403
 6404
 6405
 6406
 6407
 6408
 6409
 6410
 6411
 6412
 6413
 6414
 6415
 6416
 6417
 6418
 6419
 6420
 6421
 6422
 6423
 6424
 6425
 6426
 6427
 6428
 6429
 6430
 6431
 6432
 6433
 6434
 6435
 6436
 6437
 6438
 6439
 6440
 6441
 6442
 6443
 6444
 6445
 6446
 6447
 6448
 6449
 6450
 6451
 6452
 6453
 6454
 6455
 6456
 6457
 6458
 6459
 6460
 6461
 6462
 6463
 6464
 6465
 6466
 6467
 6468
 6469
 6470
 6471
 6472
 6473
 6474
 6475
 6476
 6477
 6478
 6479
 6480
 6481
 6482
 6483
 6484
 6485
 6486
 6487
 6488
 6489
 6490
 6491
 6492
 6493
 6494
 6495
 6496
 6497
 6498
 6499
 6500
 6501
 6502
 6503
 6504
 6505
 6506
 6507
 6508
 6509
 6510
 6511
 6512
 6513
 6514
 6515
 6516
 6517
 6518
 6519
 6520
 6521
 6522
 6523
 6524
 6525
 6526
 6527
 6528
 6529
 6530
 6531
 6532
 6533
 6534
 6535
 6536
 6537
 6538
 6539
 6540
 6541
 6542
 6543
 6544
 6545
 6546
 6547
 6548
 6549
 6550
 6551
 6552
 6553
 6554
 6555
 6556
 6557
 6558
 6559
 6560
 6561
 6562
 6563
 6564
 6565
 6566
 6567
 6568
 6569
 6570
 6571
 6572
 6573
 6574
 6575
 6576
 6577
 6578
 6579
 6580
 6581
 6582
 6583
 6584
 6585
 6586
 6587
 6588
 6589
 6590
 6591
 6592
 6593
 6594
 6595
 6596
 6597
 6598
 6599
 6600
 6601
 6602
 6603
 6604
 6605
 6606
 6607
 6608
 6609
 6610
 6611
 6612
 6613
 6614
 6615
 6616
 6617
 6618
 6619
 6620
 6621
 6622
 6623
 6624
 6625
 6626
 6627
 6628
 6629
 6630
 6631
 6632
 6633
 6634
 6635
 6636
 6637
 6638
 6639
 6640
 6641
 6642
 6643
 6644
 6645
 6646
 6647
 6648
 6649
 6650
 6651
 6652
 6653
 6654
 6655
 6656
 6657
 6658
 6659
 6660
 6661
 6662
 6663
 6664
 6665
 6666
 6667
 6668
 6669
 6670
 6671
 6672
 6673
 6674
 6675
 6676
 6677
 6678
 6679
 6680
 6681
 6682
 6683
 6684
 6685
 6686
 6687
 6688
 6689
 6690
 6691
 6692
 6693
 6694
 6695
 6696
 6697
 6698
 6699
 6700
 6701
 6702
 6703
 6704
 6705
 6706
 6707
 6708
 6709
 6710
 6711
 6712
 6713
 6714
 6715
 6716
 6717
 6718
 6719
 6720
 6721
 6722
 6723
 6724
 6725
 6726
 6727
 6728
 6729
 6730
 6731
 6732
 6733
 6734
 6735
 6736
 6737
 6738
 6739
 6740
 6741
 6742
 6743
 6744
 6745
 6746
 6747
 6748
 6749
 6750
 6751
 6752
 6753
 6754
 6755
 6756
 6757
 6758
 6759
 6760
 6761
 6762
 6763
 6764
 6765
 6766
 6767
 6768
 6769
 6770
 6771
 6772
 6773
 6774
 6775
 6776
 6777
 6778
 6779
 6780
 6781
 6782
 6783
 6784
 6785
 6786
 6787
 6788
 6789
 6790
 6791
 6792
 6793
 6794
 6795
 6796
 6797
 6798
 6799
 6800
 6801
 6802
 6803
 6804
 6805
 6806
 6807
 6808
 6809
 6810
 6811
 6812
 6813
 6814
 6815
 6816
 6817
 6818
 6819
 6820
 6821
 6822
 6823
 6824
 6825
 6826
 6827
 6828
 6829
 6830
 6831
 6832
 6833
 6834
 6835
 6836
 6837
 6838
 6839
 6840
 6841
 6842
 6843
 6844
 6845
 6846
 6847
 6848
 6849
 6850
 6851
 6852
 6853
 6854
 6855
 6856
 6857
 6858
 6859
 6860
 6861
 6862
 6863
 6864
 6865
 6866
 6867
 6868
 6869
 6870
 6871
 6872
 6873
 6874
 6875
 6876
 6877
 6878
 6879
 6880
 6881
 6882
 6883
 6884
 6885
 6886
 6887
 6888
 6889
 6890
 6891
 6892
 6893
 6894
 6895
 6896
 6897
 6898
 6899
 6900
 6901
 6902
 6903
 6904
 6905
 6906
 6907
 6908
 6909
 6910
 6911
 6912
 6913
 6914
 6915
 6916
 6917
 6918
 6919
 6920
 6921
 6922
 6923
 6924
 6925
 6926
 6927
 6928
 6929
 6930
 6931
 6932
 6933
 6934
 6935
 6936
 6937
 6938
 6939
 6940
 6941
 6942
 6943
 6944
 6945
 6946
 6947
 6948
 6949
 6950
 6951
 6952
 6953
 6954
 6955
 6956
 6957
 6958
 6959
 6960
 6961
 6962
 6963
 6964
 6965
 6966
 6967
 6968
 6969
 6970
 6971
 6972
 6973
 6974
 6975
 6976
 6977
 6978
 6979
 6980
 6981
 6982
 6983
 6984
 6985
 6986
 6987
 6988
 6989
 6990
 6991
 6992
 6993
 6994
 6995
 6996
 6997
 6998
 6999
 7000
 7001
 7002
 7003
 7004
 7005
 7006
 7007
 7008
 7009
 7010
 7011
 7012
 7013
 7014
 7015
 7016
 7017
 7018
 7019
 7020
 7021
 7022
 7023
 7024
 7025
 7026
 7027
 7028
 7029
 7030
 7031
 7032
 7033
 7034
 7035
 7036
 7037
 7038
 7039
 7040
 7041
 7042
 7043
 7044
 7045
 7046
 7047
 7048
 7049
 7050
 7051
 7052
 7053
 7054
 7055
 7056
 7057
 7058
 7059
 7060
 7061
 7062
 7063
 7064
 7065
 7066
 7067
 7068
 7069
 7070
 7071
 7072
 7073
 7074
 7075
 7076
 7077
 7078
 7079
 7080
 7081
 7082
 7083
 7084
 7085
 7086
 7087
 7088
 7089
 7090
 7091
 7092
 7093
 7094
 7095
 7096
 7097
 7098
 7099
 7100
 7101
 7102
 7103
 7104
 7105
 7106
 7107
 7108
 7109
 7110
 7111
 7112
 7113
 7114
 7115
 7116
 7117
 7118
 7119
 7120
 7121
 7122
 7123
 7124
 7125
 7126
 7127
 7128
 7129
 7130
 7131
 7132
 7133
 7134
 7135
 7136
 7137
 7138
 7139
 7140
 7141
 7142
 7143
 7144
 7145
 7146
 7147
 7148
 7149
 7150
 7151
 7152
 7153
 7154
 7155
 7156
 7157
 7158
 7159
 7160
 7161
 7162
 7163
 7164
 7165
 7166
 7167
 7168
 7169
 7170
 7171
 7172
 7173
 7174
 7175
 7176
 7177
 7178
 7179
 7180
 7181
 7182
 7183
 7184
 7185
 7186
 7187
 7188
 7189
 7190
 7191
 7192
 7193
 7194
 7195
 7196
 7197
 7198
 7199
 7200
 7201
 7202
 7203
 7204
 7205
 7206
 7207
 7208
 7209
 7210
 7211
 7212
 7213
 7214
 7215
 7216
 7217
 7218
 7219
 7220
 7221
 7222
 7223
 7224
 7225
 7226
 7227
 7228
 7229
 7230
 7231
 7232
 7233
 7234
 7235
 7236
 7237
 7238
 7239
 7240
 7241
 7242
 7243
 7244
 7245
 7246
 7247
 7248
 7249
 7250
 7251
 7252
 7253
 7254
 7255
 7256
 7257
 7258
 7259
 7260
 7261
 7262
 7263
 7264
 7265
 7266
 7267
 7268
 7269
 7270
 7271
 7272
 7273
 7274
 7275
 7276
 7277
 7278
 7279
 7280
 7281
 7282
 7283
 7284
 7285
 7286
 7287
 7288
 7289
 7290
 7291
 7292
 7293
 7294
 7295
 7296
 7297
 7298
 7299
 7300
 7301
 7302
 7303
 7304
 7305
 7306
 7307
 7308
 7309
 7310
 7311
 7312
 7313
 7314
 7315
 7316
 7317
 7318
 7319
 7320
 7321
 7322
 7323
 7324
 7325
 7326
 7327
 7328
 7329
 7330
 7331
 7332
 7333
 7334
 7335
 7336
 7337
 7338
 7339
 7340
 7341
 7342
 7343
 7344
 7345
 7346
 7347
 7348
 7349
 7350
 7351
 7352
 7353
 7354
 7355
 7356
 7357
 7358
 7359
 7360
 7361
 7362
 7363
 7364
 7365
 7366
 7367
 7368
 7369
 7370
 7371
 7372
 7373
 7374
 7375
 7376
 7377
 7378
 7379
 7380
 7381
 7382
 7383
 7384
 7385
 7386
 7387
 7388
 7389
 7390
 7391
 7392
 7393
 7394
 7395
 7396
 7397
 7398
 7399
 7400
 7401
 7402
 7403
 7404
 7405
 7406
 7407
 7408
 7409
 7410
 7411
 7412
 7413
 7414
 7415
 7416
 7417
 7418
 7419
 7420
 7421
 7422
 7423
 7424
 7425
 7426
 7427
 7428
 7429
 7430
 7431
 7432
 7433
 7434
 7435
 7436
 7437
 7438
 7439
 7440
 7441
 7442
 7443
 7444
 7445
 7446
 7447
 7448
 7449
 7450
 7451
 7452
 7453
 7454
 7455
 7456
 7457
 7458
 7459
 7460
 7461
 7462
 7463
 7464
 7465
 7466
 7467
 7468
 7469
 7470
 7471
 7472
 7473
 7474
 7475
 7476
 7477
 7478
 7479
 7480
 7481
 7482
 7483
 7484
 7485
 7486
 7487
 7488
 7489
 7490
 7491
 7492
 7493
 7494
 7495
 7496
 7497
 7498
 7499
 7500
 7501
 7502
 7503
 7504
 7505
 7506
 7507
 7508
 7509
 7510
 7511
 7512
 7513
 7514
 7515
 7516
 7517
 7518
 7519
 7520
 7521
 7522
 7523
 7524
 7525
 7526
 7527
 7528
 7529
 7530
 7531
 7532
 7533
 7534
 7535
 7536
 7537
 7538
 7539
 7540
 7541
 7542
 7543
 7544
 7545
 7546
 7547
 7548
 7549
 7550
 7551
 7552
 7553
 7554
 7555
 7556
 7557
 7558
 7559
 7560
 7561
 7562
 7563
 7564
 7565
 7566
 7567
 7568
 7569
 7570
 7571
 7572
 7573
 7574
 7575
 7576
 7577
 7578
 7579
 7580
 7581
 7582
 7583
 7584
 7585
 7586
 7587
 7588
 7589
 7590
 7591
 7592
 7593
 7594
 7595
 7596
 7597
 7598
 7599
 7600
 7601
 7602
 7603
 7604
 7605
 7606
 7607
 7608
 7609
 7610
 7611
 7612
 7613
 7614
 7615
 7616
 7617
 7618
 7619
 7620
 7621
 7622
 7623
 7624
 7625
 7626
 7627
 7628
 7629
 7630
 7631
 7632
 7633
 7634
 7635
 7636
 7637
 7638
 7639
 7640
 7641
 7642
 7643
 7644
 7645
 7646
 7647
 7648
 7649
 7650
 7651
 7652
 7653
 7654
 7655
 7656
 7657
 7658
 7659
 7660
 7661
 7662
 7663
 7664
 7665
 7666
 7667
 7668
 7669
 7670
 7671
 7672
 7673
 7674
 7675
 7676
 7677
 7678
 7679
 7680
 7681
 7682
 7683
 7684
 7685
 7686
 7687
 7688
 7689
 7690
 7691
 7692
 7693
 7694
 7695
 7696
 7697
 7698
 7699
 7700
 7701
 7702
 7703
 7704
 7705
 7706
 7707
 7708
 7709
 7710
 7711
 7712
 7713
 7714
 7715
 7716
 7717
 7718
 7719
 7720
 7721
 7722
 7723
 7724
 7725
 7726
 7727
 7728
 7729
 7730
 7731
 7732
 7733
 7734
 7735
 7736
 7737
 7738
 7739
 7740
 7741
 7742
 7743
 7744
 7745
 7746
 7747
 7748
 7749
 7750
 7751
 7752
 7753
 7754
 7755
 7756
 7757
 7758
 7759
 7760
 7761
 7762
 7763
 7764
 7765
 7766
 7767
 7768
 7769
 7770
 7771
 7772
 7773
 7774
 7775
 7776
 7777
 7778
 7779
 7780
 7781
 7782
 7783
 7784
 7785
 7786
 7787
 7788
 7789
 7790
 7791
 7792
 7793
 7794
 7795
 7796
 7797
 7798
 7799
 7800
 7801
 7802
 7803
 7804
 7805
 7806
 7807
 7808
 7809
 7810
 7811
 7812
 7813
 7814
 7815
 7816
 7817
 7818
 7819
 7820
 7821
 7822
 7823
 7824
 7825
 7826
 7827
 7828
 7829
 7830
 7831
 7832
 7833
 7834
 7835
 7836
 7837
 7838
 7839
 7840
 7841
 7842
 7843
 7844
 7845
 7846
 7847
 7848
 7849
 7850
 7851
 7852
 7853
 7854
 7855
 7856
 7857
 7858
 7859
 7860
 7861
 7862
 7863
 7864
 7865
 7866
 7867
 7868
 7869
 7870
 7871
 7872
 7873
 7874
 7875
 7876
 7877
 7878
 7879
 7880
 7881
 7882
 7883
 7884
 7885
 7886
 7887
 7888
 7889
 7890
 7891
 7892
 7893
 7894
 7895
 7896
 7897
 7898
 7899
 7900
 7901
 7902
 7903
 7904
 7905
 7906
 7907
 7908
 7909
 7910
 7911
 7912
 7913
 7914
 7915
 7916
 7917
 7918
 7919
 7920
 7921
 7922
 7923
 7924
 7925
 7926
 7927
 7928
 7929
 7930
 7931
 7932
 7933
 7934
 7935
 7936
 7937
 7938
 7939
 7940
 7941
 7942
 7943
 7944
 7945
 7946
 7947
 7948
 7949
 7950
 7951
 7952
 7953
 7954
 7955
 7956
 7957
 7958
 7959
 7960
 7961
 7962
 7963
 7964
 7965
 7966
 7967
 7968
 7969
 7970
 7971
 7972
 7973
 7974
 7975
 7976
 7977
 7978
 7979
 7980
 7981
 7982
 7983
 7984
 7985
 7986
 7987
 7988
 7989
 7990
 7991
 7992
 7993
 7994
 7995
 7996
 7997
 7998
 7999
 8000
 8001
 8002
 8003
 8004
 8005
 8006
 8007
 8008
 8009
 8010
 8011
 8012
 8013
 8014
 8015
 8016
 8017
 8018
 8019
 8020
 8021
 8022
 8023
 8024
 8025
 8026
 8027
 8028
 8029
 8030
 8031
 8032
 8033
 8034
 8035
 8036
 8037
 8038
 8039
 8040
 8041
 8042
 8043
 8044
 8045
 8046
 8047
 8048
 8049
 8050
 8051
 8052
 8053
 8054
 8055
 8056
 8057
 8058
 8059
 8060
 8061
 8062
 8063
 8064
 8065
 8066
 8067
 8068
 8069
 8070
 8071
 8072
 8073
 8074
 8075
 8076
 8077
 8078
 8079
 8080
 8081
 8082
 8083
 8084
 8085
 8086
 8087
 8088
 8089
 8090
 8091
 8092
 8093
 8094
 8095
 8096
 8097
 8098
 8099
 8100
 8101
 8102
 8103
 8104
 8105
 8106
 8107
 8108
 8109
 8110
 8111
 8112
 8113
 8114
 8115
 8116
 8117
 8118
 8119
 8120
 8121
 8122
 8123
 8124
 8125
 8126
 8127
 8128
 8129
 8130
 8131
 8132
 8133
 8134
 8135
 8136
 8137
 8138
 8139
 8140
 8141
 8142
 8143
 8144
 8145
 8146
 8147
 8148
 8149
 8150
 8151
 8152
 8153
 8154
 8155
 8156
 8157
 8158
 8159
 8160
 8161
 8162
 8163
 8164
 8165
 8166
 8167
 8168
 8169
 8170
 8171
 8172
 8173
 8174
 8175
 8176
 8177
 8178
 8179
 8180
 8181
 8182
 8183
 8184
 8185
 8186
 8187
 8188
 8189
 8190
 8191
 8192
 8193
 8194
 8195
 8196
 8197
 8198
 8199
 8200
 8201
 8202
 8203
 8204
 8205
 8206
 8207
 8208
 8209
 8210
 8211
 8212
 8213
 8214
 8215
 8216
 8217
 8218
 8219
 8220
 8221
 8222
 8223
 8224
 8225
 8226
 8227
 8228
 8229
 8230
 8231
 8232
 8233
 8234
 8235
 8236
 8237
 8238
 8239
 8240
 8241
 8242
 8243
 8244
 8245
 8246
 8247
 8248
 8249
 8250
 8251
 8252
 8253
 8254
 8255
 8256
 8257
 8258
 8259
 8260
 8261
 8262
 8263
 8264
 8265
 8266
 8267
 8268
 8269
 8270
 8271
 8272
 8273
 8274
 8275
 8276
 8277
 8278
 8279
 8280
 8281
 8282
 8283
 8284
 8285
 8286
 8287
 8288
 8289
 8290
 8291
 8292
 8293
 8294
 8295
 8296
 8297
 8298
 8299
 8300
 8301
 8302
 8303
 8304
 8305
 8306
 8307
 8308
 8309
 8310
 8311
 8312
 8313
 8314
 8315
 8316
 8317
 8318
 8319
 8320
 8321
 8322
 8323
 8324
 8325
 8326
 8327
 8328
 8329
 8330
 8331
 8332
 8333
 8334
 8335
 8336
 8337
 8338
 8339
 8340
 8341
 8342
 8343
 8344
 8345
 8346
 8347
 8348
 8349
 8350
 8351
 8352
 8353
 8354
 8355
 8356
 8357
 8358
 8359
 8360
 8361
 8362
 8363
 8364
 8365
 8366
 8367
 8368
 8369
 8370
 8371
 8372
 8373
 8374
 8375
 8376
 8377
 8378
 8379
 8380
 8381
 8382
 8383
 8384
 8385
 8386
 8387
 8388
 8389
 8390
 8391
 8392
 8393
 8394
 8395
 8396
 8397
 8398
 8399
 8400
 8401
 8402
 8403
 8404
 8405
 8406
 8407
 8408
 8409
 8410
 8411
 8412
 8413
 8414
 8415
 8416
 8417
 8418
 8419
 8420
 8421
 8422
 8423
 8424
 8425
 8426
 8427
 8428
 8429
 8430
 8431
 8432
 8433
 8434
 8435
 8436
 8437
 8438
 8439
 8440
 8441
 8442
 8443
 8444
 8445
 8446
 8447
 8448
 8449
 8450
 8451
 8452
 8453
 8454
 8455
 8456
 8457
 8458
 8459
 8460
 8461
 8462
 8463
 8464
 8465
 8466
 8467
 8468
 8469
 8470
 8471
 8472
 8473
 8474
 8475
 8476
 8477
 8478
 8479
 8480
 8481
 8482
 8483
 8484
 8485
 8486
 8487
 8488
 8489
 8490
 8491
 8492
 8493
 8494
 8495
 8496
 8497
 8498
 8499
 8500
 8501
 8502
 8503
 8504
 8505
 8506
 8507
 8508
 8509
 8510
 8511
 8512
 8513
 8514
 8515
 8516
 8517
 8518
 8519
 8520
 8521
 8522
 8523
 8524
 8525
 8526
 8527
 8528
 8529
 8530
 8531
 8532
 8533
 8534
 8535
 8536
 8537
 8538
 8539
 8540
 8541
 8542
 8543
 8544
 8545
 8546
 8547
 8548
 8549
 8550
 8551
 8552
 8553
 8554
 8555
 8556
 8557
 8558
 8559
 8560
 8561
 8562
 8563
 8564
 8565
 8566
 8567
 8568
 8569
 8570
 8571
 8572
 8573
 8574
 8575
 8576
 8577
 8578
 8579
 8580
 8581
 8582
 8583
 8584
 8585
 8586
 8587
 8588
 8589
 8590
 8591
 8592
 8593
 8594
 8595
 8596
 8597
 8598
 8599
 8600
 8601
 8602
 8603
 8604
 8605
 8606
 8607
 8608
 8609
 8610
 8611
 8612
 8613
 8614
 8615
 8616
 8617
 8618
 8619
 8620
 8621
 8622
 8623
 8624
 8625
 8626
 8627
 8628
 8629
 8630
 8631
 8632
 8633
 8634
 8635
 8636
 8637
 8638
 8639
 8640
 8641
 8642
 8643
 8644
 8645
 8646
 8647
 8648
 8649
 8650
 8651
 8652
 8653
 8654
 8655
 8656
 8657
 8658
 8659
 8660
 8661
 8662
 8663
 8664
 8665
 8666
 8667
 8668
 8669
 8670
 8671
 8672
 8673
 8674
 8675
 8676
 8677
 8678
 8679
 8680
 8681
 8682
 8683
 8684
 8685
 8686
 8687
 8688
 8689
 8690
 8691
 8692
 8693
 8694
 8695
 8696
 8697
 8698
 8699
 8700
 8701
 8702
 8703
 8704
 8705
 8706
 8707
 8708
 8709
 8710
 8711
 8712
 8713
 8714
 8715
 8716
 8717
 8718
 8719
 8720
 8721
 8722
 8723
 8724
 8725
 8726
 8727
 8728
 8729
 8730
 8731
 8732
 8733
 8734
 8735
 8736
 8737
 8738
 8739
 8740
 8741
 8742
 8743
 8744
 8745
 8746
 8747
 8748
 8749
 8750
 8751
 8752
 8753
 8754
 8755
 8756
 8757
 8758
 8759
 8760
 8761
 8762
 8763
 8764
 8765
 8766
 8767
 8768
 8769
 8770
 8771
 8772
 8773
 8774
 8775
 8776
 8777
 8778
 8779
 8780
 8781
 8782
 8783
 8784
 8785
 8786
 8787
 8788
 8789
 8790
 8791
 8792
 8793
 8794
 8795
 8796
 8797
 8798
 8799
 8800
 8801
 8802
 8803
 8804
 8805
 8806
 8807
 8808
 8809
 8810
 8811
 8812
 8813
 8814
 8815
 8816
 8817
 8818
 8819
 8820
 8821
 8822
 8823
 8824
 8825
 8826
 8827
 8828
 8829
 8830
 8831
 8832
 8833
 8834
 8835
 8836
 8837
 8838
 8839
 8840
 8841
 8842
 8843
 8844
 8845
 8846
 8847
 8848
 8849
 8850
 8851
 8852
 8853
 8854
 8855
 8856
 8857
 8858
 8859
 8860
 8861
 8862
 8863
 8864
 8865
 8866
 8867
 8868
 8869
 8870
 8871
 8872
 8873
 8874
 8875
 8876
 8877
 8878
 8879
 8880
 8881
 8882
 8883
 8884
 8885
 8886
 8887
 8888
 8889
 8890
 8891
 8892
 8893
 8894
 8895
 8896
 8897
 8898
 8899
 8900
 8901
 8902
 8903
 8904
 8905
 8906
 8907
 8908
 8909
 8910
 8911
 8912
 8913
 8914
 8915
 8916
 8917
 8918
 8919
 8920
 8921
 8922
 8923
 8924
 8925
 8926
 8927
 8928
 8929
 8930
 8931
 8932
 8933
 8934
 8935
 8936
 8937
 8938
 8939
 8940
 8941
 8942
 8943
 8944
 8945
 8946
 8947
 8948
 8949
 8950
 8951
 8952
 8953
 8954
 8955
 8956
 8957
 8958
 8959
 8960
 8961
 8962
 8963
 8964
 8965
 8966
 8967
 8968
 8969
 8970
 8971
 8972
 8973
 8974
 8975
 8976
 8977
 8978
 8979
 8980
 8981
 8982
 8983
 8984
 8985
 8986
 8987
 8988
 8989
 8990
 8991
 8992
 8993
 8994
 8995
 8996
 8997
 8998
 8999
 9000
 9001
 9002
 9003
 9004
 9005
 9006
 9007
 9008
 9009
 9010
 9011
 9012
 9013
 9014
 9015
 9016
 9017
 9018
 9019
 9020
 9021
 9022
 9023
 9024
 9025
 9026
 9027
 9028
 9029
 9030
 9031
 9032
 9033
 9034
 9035
 9036
 9037
 9038
 9039
 9040
 9041
 9042
 9043
 9044
 9045
 9046
 9047
 9048
 9049
 9050
 9051
 9052
 9053
 9054
 9055
 9056
 9057
 9058
 9059
 9060
 9061
 9062
 9063
 9064
 9065
 9066
 9067
 9068
 9069
 9070
 9071
 9072
 9073
 9074
 9075
 9076
 9077
 9078
 9079
 9080
 9081
 9082
 9083
 9084
 9085
 9086
 9087
 9088
 9089
 9090
 9091
 9092
 9093
 9094
 9095
 9096
 9097
 9098
 9099
 9100
 9101
 9102
 9103
 9104
 9105
 9106
 9107
 9108
 9109
 9110
 9111
 9112
 9113
 9114
 9115
 9116
 9117
 9118
 9119
 9120
 9121
 9122
 9123
 9124
 9125
 9126
 9127
 9128
 9129
 9130
 9131
 9132
 9133
 9134
 9135
 9136
 9137
 9138
 9139
 9140
 9141
 9142
 9143
 9144
 9145
 9146
 9147
 9148
 9149
 9150
 9151
 9152
 9153
 9154
 9155
 9156
 9157
 9158
 9159
 9160
 9161
 9162
 9163
 9164
 9165
 9166
 9167
 9168
 9169
 9170
 9171
 9172
 9173
 9174
 9175
 9176
 9177
 9178
 9179
 9180
 9181
 9182
 9183
 9184
 9185
 9186
 9187
 9188
 9189
 9190
 9191
 9192
 9193
 9194
 9195
 9196
 9197
 9198
 9199
 9200
 9201
 9202
 9203
 9204
 9205
 9206
 9207
 9208
 9209
 9210
 9211
 9212
 9213
 9214
 9215
 9216
 9217
 9218
 9219
 9220
 9221
 9222
 9223
 9224
 9225
 9226
 9227
 9228
 9229
 9230
 9231
 9232
 9233
 9234
 9235
 9236
 9237
 9238
 9239
 9240
 9241
 9242
 9243
 9244
 9245
 9246
 9247
 9248
 9249
 9250
 9251
 9252
 9253
 9254
 9255
 9256
 9257
 9258
 9259
 9260
 9261
 9262
 9263
 9264
 9265
 9266
 9267
 9268
 9269
 9270
 9271
 9272
 9273
 9274
 9275
 9276
 9277
 9278
 9279
 9280
 9281
 9282
 9283
 9284
 9285
 9286
 9287
 9288
 9289
 9290
 9291
 9292
 9293
 9294
 9295
 9296
 9297
 9298
 9299
 9300
 9301
 9302
 9303
 9304
 9305
 9306
 9307
 9308
 9309
 9310
 9311
 9312
 9313
 9314
 9315
 9316
 9317
 9318
 9319
 9320
 9321
 9322
 9323
 9324
 9325
 9326
 9327
 9328
 9329
 9330
 9331
 9332
 9333
 9334
 9335
 9336
 9337
 9338
 9339
 9340
 9341
 9342
 9343
 9344
 9345
 9346
 9347
 9348
 9349
 9350
 9351
 9352
 9353
 9354
 9355
 9356
 9357
 9358
 9359
 9360
 9361
 9362
 9363
 9364
 9365
 9366
 9367
 9368
 9369
 9370
 9371
 9372
 9373
 9374
 9375
 9376
 9377
 9378
 9379
 9380
 9381
 9382
 9383
 9384
 9385
 9386
 9387
 9388
 9389
 9390
 9391
 9392
 9393
 9394
 9395
 9396
 9397
 9398
 9399
 9400
 9401
 9402
 9403
 9404
 9405
 9406
 9407
 9408
 9409
 9410
 9411
 9412
 9413
 9414
 9415
 9416
 9417
 9418
 9419
 9420
 9421
 9422
 9423
 9424
 9425
 9426
 9427
 9428
 9429
 9430
 9431
 9432
 9433
 9434
 9435
 9436
 9437
 9438
 9439
 9440
 9441
 9442
 9443
 9444
 9445
 9446
 9447
 9448
 9449
 9450
 9451
 9452
 9453
 9454
 9455
 9456
 9457
 9458
 9459
 9460
 9461
 9462
 9463
 9464
 9465
 9466
 9467
 9468
 9469
 9470
 9471
 9472
 9473
 9474
 9475
 9476
 9477
 9478
 9479
 9480
 9481
 9482
 9483
 9484
 9485
 9486
 9487
 9488
 9489
 9490
 9491
 9492
 9493
 9494
 9495
 9496
 9497
 9498
 9499
 9500
 9501
 9502
 9503
 9504
 9505
 9506
 9507
 9508
 9509
 9510
 9511
 9512
 9513
 9514
 9515
 9516
 9517
 9518
 9519
 9520
 9521
 9522
 9523
 9524
 9525
 9526
 9527
 9528
 9529
 9530
 9531
 9532
 9533
 9534
 9535
 9536
 9537
 9538
 9539
 9540
 9541
 9542
 9543
 9544
 9545
 9546
 9547
 9548
 9549
 9550
 9551
 9552
 9553
 9554
 9555
 9556
 9557
 9558
 9559
 9560
 9561
 9562
 9563
 9564
 9565
 9566
 9567
 9568
 9569
 9570
 9571
 9572
 9573
 9574
 9575
 9576
 9577
 9578
 9579
 9580
 9581
 9582
 9583
 9584
 9585
 9586
 9587
 9588
 9589
 9590
 9591
 9592
 9593
 9594
 9595
 9596
 9597
 9598
 9599
 9600
 9601
 9602
 9603
 9604
 9605
 9606
 9607
 9608
 9609
 9610
 9611
 9612
 9613
 9614
 9615
 9616
 9617
 9618
 9619
 9620
 9621
 9622
 9623
 9624
 9625
 9626
 9627
 9628
 9629
 9630
 9631
 9632
 9633
 9634
 9635
 9636
 9637
 9638
 9639
 9640
 9641
 9642
 9643
 9644
 9645
 9646
 9647
 9648
 9649
 9650
 9651
 9652
 9653
 9654
 9655
 9656
 9657
 9658
 9659
 9660
 9661
 9662
 9663
 9664
 9665
 9666
 9667
 9668
 9669
 9670
 9671
 9672
 9673
 9674
 9675
 9676
 9677
 9678
 9679
 9680
 9681
 9682
 9683
 9684
 9685
 9686
 9687
 9688
 9689
 9690
 9691
 9692
 9693
 9694
 9695
 9696
 9697
 9698
 9699
 9700
 9701
 9702
 9703
 9704
 9705
 9706
 9707
 9708
 9709
 9710
 9711
 9712
 9713
 9714
 9715
 9716
 9717
 9718
 9719
 9720
 9721
 9722
 9723
 9724
 9725
 9726
 9727
 9728
 9729
 9730
 9731
 9732
 9733
 9734
 9735
 9736
 9737
 9738
 9739
 9740
 9741
 9742
 9743
 9744
 9745
 9746
 9747
 9748
 9749
 9750
 9751
 9752
 9753
 9754
 9755
 9756
 9757
 9758
 9759
 9760
 9761
 9762
 9763
 9764
 9765
 9766
 9767
 9768
 9769
 9770
 9771
 9772
 9773
 9774
 9775
 9776
 9777
 9778
 9779
 9780
 9781
 9782
 9783
 9784
 9785
 9786
 9787
 9788
 9789
 9790
 9791
 9792
 9793
 9794
 9795
 9796
 9797
 9798
 9799
 9800
 9801
 9802
 9803
 9804
 9805
 9806
 9807
 9808
 9809
 9810
 9811
 9812
 9813
 9814
 9815
 9816
 9817
 9818
 9819
 9820
 9821
 9822
 9823
 9824
 9825
 9826
 9827
 9828
 9829
 9830
 9831
 9832
 9833
 9834
 9835
 9836
 9837
 9838
 9839
 9840
 9841
 9842
 9843
 9844
 9845
 9846
 9847
 9848
 9849
 9850
 9851
 9852
 9853
 9854
 9855
 9856
 9857
 9858
 9859
 9860
 9861
 9862
 9863
 9864
 9865
 9866
 9867
 9868
 9869
 9870
 9871
 9872
 9873
 9874
 9875
 9876
 9877
 9878
 9879
 9880
 9881
 9882
 9883
 9884
 9885
 9886
 9887
 9888
 9889
 9890
 9891
 9892
 9893
 9894
 9895
 9896
 9897
 9898
 9899
 9900
 9901
 9902
 9903
 9904
 9905
 9906
 9907
 9908
 9909
 9910
 9911
 9912
 9913
 9914
 9915
 9916
 9917
 9918
 9919
 9920
 9921
 9922
 9923
 9924
 9925
 9926
 9927
 9928
 9929
 9930
 9931
 9932
 9933
 9934
 9935
 9936
 9937
 9938
 9939
 9940
 9941
 9942
 9943
 9944
 9945
 9946
 9947
 9948
 9949
 9950
 9951
 9952
 9953
 9954
 9955
 9956
 9957
 9958
 9959
 9960
 9961
 9962
 9963
 9964
 9965
 9966
 9967
 9968
 9969
 9970
 9971
 9972
 9973
 9974
 9975
 9976
 9977
 9978
 9979
 9980
 9981
 9982
 9983
 9984
 9985
 9986
 9987
 9988
 9989
 9990
 9991
 9992
 9993
 9994
 9995
 9996
 9997
 9998
 9999
10000
10001
10002
10003
10004
10005
10006
10007
10008
10009
10010
10011
10012
10013
10014
10015
10016
10017
10018
10019
10020
10021
10022
10023
10024
10025
10026
10027
10028
10029
10030
10031
10032
10033
10034
10035
10036
10037
10038
10039
10040
10041
10042
10043
10044
10045
10046
10047
10048
10049
10050
10051
10052
10053
10054
10055
10056
10057
10058
10059
10060
10061
10062
10063
10064
10065
10066
10067
10068
10069
10070
10071
10072
10073
10074
10075
10076
10077
10078
10079
10080
10081
10082
10083
10084
10085
10086
10087
10088
10089
10090
10091
10092
10093
10094
10095
10096
10097
10098
10099
10100
10101
10102
10103
10104
10105
10106
10107
10108
10109
10110
10111
10112
10113
10114
10115
10116
10117
10118
10119
10120
10121
10122
10123
10124
10125
10126
10127
10128
10129
10130
10131
10132
10133
10134
10135
10136
10137
10138
10139
10140
10141
10142
10143
10144
10145
10146
10147
10148
10149
10150
10151
10152
10153
10154
10155
10156
10157
10158
10159
10160
10161
10162
10163
10164
10165
10166
10167
10168
10169
10170
10171
10172
10173
10174
10175
10176
10177
10178
10179
10180
10181
10182
10183
10184
10185
10186
10187
10188
10189
10190
10191
10192
10193
10194
10195
10196
10197
10198
10199
10200
10201
10202
10203
10204
10205
10206
10207
10208
10209
10210
10211
10212
10213
10214
10215
10216
10217
10218
10219
10220
10221
10222
10223
10224
10225
10226
10227
10228
10229
10230
10231
10232
10233
10234
10235
10236
10237
10238
10239
10240
10241
10242
10243
10244
10245
10246
10247
10248
10249
10250
10251
10252
10253
10254
10255
10256
10257
10258
10259
10260
10261
10262
10263
10264
10265
10266
10267
10268
10269
10270
10271
10272
10273
10274
10275
10276
10277
10278
10279
10280
10281
10282
10283
10284
10285
10286
10287
10288
10289
10290
10291
10292
10293
10294
10295
10296
10297
10298
10299
10300
10301
10302
10303
10304
10305
10306
10307
10308
10309
10310
10311
10312
10313
10314
10315
10316
10317
10318
10319
10320
10321
10322
10323
10324
10325
10326
10327
10328
10329
10330
10331
10332
10333
10334
10335
10336
10337
10338
10339
10340
10341
10342
10343
10344
10345
10346
10347
10348
10349
10350
10351
10352
10353
10354
10355
10356
10357
10358
10359
10360
10361
10362
10363
10364
10365
10366
10367
10368
10369
10370
10371
10372
10373
10374
10375
10376
10377
10378
10379
10380
10381
10382
10383
10384
10385
10386
10387
10388
10389
10390
10391
10392
10393
10394
10395
10396
10397
10398
10399
10400
10401
10402
10403
10404
10405
10406
10407
10408
10409
10410
10411
10412
10413
10414
10415
10416
10417
10418
10419
10420
10421
10422
10423
10424
10425
10426
10427
10428
10429
10430
10431
10432
10433
10434
10435
10436
10437
10438
10439
10440
10441
10442
10443
10444
10445
10446
10447
10448
10449
10450
10451
10452
10453
10454
10455
10456
10457
10458
10459
10460
10461
10462
10463
10464
10465
10466
10467
10468
10469
10470
10471
10472
10473
10474
10475
10476
10477
10478
10479
10480
10481
10482
10483
10484
10485
10486
10487
10488
10489
10490
10491
10492
10493
10494
10495
10496
10497
10498
10499
10500
10501
10502
10503
10504
10505
10506
10507
10508
10509
10510
10511
10512
10513
10514
10515
10516
10517
10518
10519
10520
10521
10522
10523
10524
10525
10526
10527
10528
10529
10530
10531
10532
10533
10534
10535
10536
10537
10538
10539
10540
10541
10542
10543
10544
10545
10546
10547
10548
10549
10550
10551
10552
10553
10554
10555
10556
10557
10558
10559
10560
10561
10562
10563
10564
10565
10566
10567
10568
10569
10570
10571
10572
10573
10574
10575
10576
10577
10578
10579
10580
10581
10582
10583
10584
10585
10586
10587
10588
10589
10590
10591
10592
10593
10594
10595
10596
10597
10598
10599
10600
10601
10602
10603
10604
10605
10606
10607
10608
10609
10610
10611
10612
10613
10614
10615
10616
10617
10618
10619
10620
10621
10622
10623
10624
10625
10626
10627
10628
10629
10630
10631
10632
10633
10634
10635
10636
10637
10638
10639
10640
10641
10642
10643
10644
10645
10646
10647
10648
10649
10650
10651
10652
10653
10654
10655
10656
10657
10658
10659
10660
10661
10662
10663
10664
10665
10666
10667
10668
10669
10670
10671
10672
10673
10674
10675
10676
10677
10678
10679
10680
10681
10682
10683
10684
10685
10686
10687
10688
10689
10690
10691
10692
10693
10694
10695
10696
10697
10698
10699
10700
10701
10702
10703
10704
10705
10706
10707
10708
10709
10710
10711
10712
10713
10714
10715
10716
10717
10718
10719
10720
10721
10722
10723
10724
10725
10726
10727
10728
10729
10730
10731
10732
10733
10734
10735
10736
10737
10738
10739
10740
10741
10742
10743
10744
10745
10746
10747
10748
10749
10750
10751
10752
10753
10754
10755
10756
10757
10758
10759
10760
10761
10762
10763
10764
10765
10766
10767
10768
10769
10770
10771
10772
10773
10774
10775
10776
10777
10778
10779
10780
10781
10782
10783
10784
10785
10786
10787
10788
10789
10790
10791
10792
10793
10794
10795
10796
10797
10798
10799
10800
10801
10802
10803
10804
10805
10806
10807
10808
10809
10810
10811
10812
10813
10814
10815
10816
10817
10818
10819
10820
10821
10822
10823
10824
10825
10826
10827
10828
10829
10830
10831
10832
10833
10834
10835
10836
10837
10838
10839
10840
10841
10842
10843
10844
10845
10846
10847
10848
10849
10850
10851
10852
10853
10854
10855
10856
10857
10858
10859
10860
10861
10862
10863
10864
10865
10866
10867
10868
10869
10870
10871
10872
10873
10874
10875
10876
10877
10878
10879
10880
10881
10882
10883
10884
10885
10886
10887
10888
10889
10890
10891
10892
10893
10894
10895
10896
10897
10898
10899
10900
10901
10902
10903
10904
10905
10906
10907
10908
10909
10910
10911
10912
10913
10914
10915
10916
10917
10918
10919
10920
10921
10922
10923
10924
10925
10926
10927
10928
10929
10930
10931
10932
10933
10934
10935
10936
10937
10938
10939
10940
10941
10942
10943
10944
10945
10946
10947
10948
10949
10950
10951
10952
10953
10954
10955
10956
10957
10958
10959
10960
10961
10962
10963
10964
10965
10966
10967
10968
10969
10970
10971
10972
10973
10974
10975
10976
10977
10978
10979
10980
10981
10982
10983
10984
10985
10986
10987
10988
10989
10990
10991
10992
10993
10994
10995
10996
10997
10998
10999
11000
11001
11002
11003
11004
11005
11006
11007
11008
11009
11010
11011
11012
11013
11014
11015
11016
11017
11018
11019
11020
11021
11022
11023
11024
11025
11026
11027
11028
11029
11030
11031
11032
11033
11034
11035
11036
11037
11038
11039
11040
11041
11042
11043
11044
11045
11046
11047
11048
11049
11050
11051
11052
11053
11054
11055
11056
11057
11058
11059
11060
11061
11062
11063
11064
11065
11066
11067
11068
11069
11070
11071
11072
11073
11074
11075
11076
11077
11078
11079
11080
11081
11082
11083
11084
11085
11086
11087
11088
11089
11090
11091
11092
11093
11094
11095
11096
11097
11098
11099
11100
11101
11102
11103
11104
11105
11106
11107
11108
11109
11110
11111
11112
11113
11114
11115
11116
11117
11118
11119
11120
11121
11122
11123
11124
11125
11126
11127
11128
11129
11130
11131
11132
11133
11134
11135
11136
11137
11138
11139
11140
11141
11142
11143
11144
11145
11146
11147
11148
11149
11150
11151
11152
11153
11154
11155
11156
11157
11158
11159
11160
11161
11162
11163
11164
11165
11166
11167
11168
11169
11170
11171
11172
11173
11174
11175
11176
11177
11178
11179
11180
11181
11182
11183
11184
11185
11186
11187
11188
11189
11190
11191
11192
11193
11194
11195
11196
11197
11198
11199
11200
11201
11202
11203
11204
11205
11206
11207
11208
11209
11210
11211
11212
11213
11214
11215
11216
11217
11218
11219
11220
11221
11222
11223
11224
11225
11226
11227
11228
11229
11230
11231
11232
11233
11234
11235
11236
11237
11238
11239
11240
11241
11242
11243
11244
11245
11246
11247
11248
11249
11250
11251
11252
11253
11254
11255
11256
11257
11258
11259
11260
11261
11262
11263
11264
11265
11266
11267
11268
11269
11270
11271
11272
11273
11274
11275
11276
11277
11278
11279
11280
11281
11282
11283
11284
11285
11286
11287
11288
11289
11290
11291
11292
11293
11294
11295
11296
11297
11298
11299
11300
11301
11302
11303
11304
11305
11306
11307
11308
11309
11310
11311
11312
11313
11314
11315
11316
11317
11318
11319
11320
11321
11322
11323
11324
11325
11326
11327
11328
11329
11330
11331
11332
11333
11334
11335
11336
11337
11338
11339
11340
11341
11342
11343
11344
11345
11346
11347
11348
11349
11350
11351
11352
11353
11354
11355
11356
11357
11358
11359
11360
11361
11362
11363
11364
11365
11366
11367
11368
11369
11370
11371
11372
11373
11374
11375
11376
11377
11378
11379
11380
11381
11382
11383
11384
11385
11386
11387
11388
11389
11390
11391
11392
11393
11394
11395
11396
11397
11398
11399
11400
11401
11402
11403
11404
11405
11406
11407
11408
11409
11410
11411
11412
11413
11414
11415
11416
11417
11418
11419
11420
11421
11422
11423
11424
11425
11426
11427
11428
11429
11430
11431
11432
11433
11434
11435
11436
11437
11438
11439
11440
11441
11442
11443
11444
11445
11446
11447
11448
11449
11450
11451
11452
11453
11454
11455
11456
11457
11458
11459
11460
11461
11462
11463
11464
11465
11466
11467
11468
11469
11470
11471
11472
11473
11474
11475
11476
11477
11478
11479
11480
11481
11482
11483
11484
11485
11486
11487
11488
11489
11490
11491
11492
11493
11494
11495
11496
11497
11498
11499
11500
11501
11502
11503
11504
11505
11506
11507
11508
11509
11510
11511
11512
11513
11514
11515
11516
11517
11518
11519
11520
11521
11522
11523
11524
11525
11526
11527
11528
11529
11530
11531
11532
11533
11534
11535
11536
11537
11538
11539
11540
11541
11542
11543
11544
11545
11546
11547
11548
11549
11550
11551
11552
11553
11554
11555
11556
11557
11558
11559
11560
11561
11562
11563
11564
11565
11566
11567
11568
11569
11570
11571
11572
11573
11574
11575
11576
11577
11578
11579
11580
11581
11582
11583
11584
11585
11586
11587
11588
11589
11590
11591
11592
11593
11594
11595
11596
11597
11598
11599
11600
11601
11602
11603
11604
11605
11606
11607
11608
11609
11610
11611
11612
11613
11614
11615
11616
11617
11618
11619
11620
11621
11622
11623
11624
11625
11626
11627
11628
11629
11630
11631
11632
11633
11634
11635
11636
11637
11638
11639
11640
11641
11642
11643
11644
11645
11646
11647
11648
11649
11650
11651
11652
11653
11654
11655
11656
11657
11658
11659
11660
11661
11662
11663
11664
11665
11666
11667
11668
11669
11670
11671
11672
11673
11674
11675
11676
11677
11678
11679
11680
11681
11682
11683
11684
11685
11686
11687
11688
11689
11690
11691
11692
11693
11694
11695
11696
11697
11698
11699
11700
11701
11702
11703
11704
11705
11706
11707
11708
11709
11710
11711
11712
11713
11714
11715
11716
11717
11718
11719
11720
11721
11722
11723
11724
11725
11726
11727
11728
11729
11730
11731
11732
11733
11734
11735
11736
11737
11738
11739
11740
11741
11742
11743
11744
11745
11746
11747
11748
11749
11750
11751
11752
11753
11754
11755
11756
11757
11758
11759
11760
11761
11762
11763
11764
11765
11766
11767
11768
11769
11770
11771
11772
11773
11774
11775
11776
11777
11778
11779
11780
11781
11782
11783
11784
11785
11786
11787
11788
11789
11790
11791
11792
11793
11794
11795
11796
11797
11798
11799
11800
11801
11802
11803
11804
11805
11806
11807
11808
11809
11810
11811
11812
11813
11814
11815
11816
11817
11818
11819
11820
11821
11822
11823
11824
11825
11826
11827
11828
11829
11830
11831
11832
11833
11834
11835
11836
11837
11838
11839
11840
11841
11842
11843
11844
11845
11846
11847
11848
11849
11850
11851
11852
11853
11854
11855
11856
11857
11858
11859
11860
11861
11862
11863
11864
11865
11866
11867
11868
11869
11870
11871
11872
11873
11874
11875
11876
11877
11878
11879
11880
11881
11882
11883
11884
11885
11886
11887
11888
11889
11890
11891
11892
11893
11894
11895
11896
11897
11898
11899
11900
11901
11902
11903
11904
11905
11906
11907
11908
11909
11910
11911
11912
11913
11914
11915
11916
11917
11918
11919
11920
11921
11922
11923
11924
11925
11926
11927
11928
11929
11930
11931
11932
11933
11934
11935
11936
11937
11938
11939
11940
11941
11942
11943
11944
11945
11946
11947
11948
11949
11950
11951
11952
11953
11954
11955
11956
11957
11958
11959
11960
11961
11962
11963
11964
11965
11966
11967
11968
11969
11970
11971
11972
11973
11974
11975
11976
11977
11978
11979
11980
11981
11982
11983
11984
11985
11986
11987
11988
11989
11990
11991
11992
11993
11994
11995
11996
11997
11998
11999
12000
12001
12002
12003
12004
12005
12006
12007
12008
12009
12010
12011
12012
12013
12014
12015
12016
12017
12018
12019
12020
12021
12022
12023
12024
12025
12026
12027
12028
12029
12030
12031
12032
12033
12034
12035
12036
12037
12038
12039
12040
12041
12042
12043
12044
12045
12046
12047
12048
12049
12050
12051
12052
12053
12054
12055
12056
12057
12058
12059
12060
12061
12062
12063
12064
12065
12066
12067
12068
12069
12070
12071
12072
12073
12074
12075
12076
12077
12078
12079
12080
12081
12082
12083
12084
12085
12086
12087
12088
12089
12090
12091
12092
12093
12094
12095
12096
12097
12098
12099
12100
12101
12102
12103
12104
12105
12106
12107
12108
12109
12110
12111
12112
12113
12114
12115
12116
12117
12118
12119
12120
12121
12122
12123
12124
12125
12126
12127
12128
12129
12130
12131
12132
12133
12134
12135
12136
12137
12138
12139
12140
12141
12142
12143
12144
12145
12146
12147
12148
12149
12150
12151
12152
12153
12154
12155
12156
12157
12158
12159
12160
12161
12162
12163
12164
12165
12166
12167
12168
12169
12170
12171
12172
12173
12174
12175
12176
12177
12178
12179
12180
12181
12182
12183
12184
12185
12186
12187
12188
12189
12190
12191
12192
12193
12194
12195
12196
12197
12198
12199
12200
12201
12202
12203
12204
12205
12206
12207
12208
12209
12210
12211
12212
12213
12214
12215
12216
12217
12218
12219
12220
12221
12222
12223
12224
12225
12226
12227
12228
12229
12230
12231
12232
12233
12234
12235
12236
12237
12238
12239
12240
12241
12242
12243
12244
12245
12246
12247
12248
12249
12250
12251
12252
12253
12254
12255
12256
12257
12258
12259
12260
12261
12262
12263
12264
12265
12266
12267
12268
12269
12270
12271
12272
12273
12274
12275
12276
12277
12278
12279
12280
12281
12282
12283
12284
12285
12286
12287
12288
12289
12290
12291
12292
12293
12294
12295
12296
12297
12298
12299
12300
12301
12302
12303
12304
12305
12306
12307
12308
12309
12310
12311
12312
12313
12314
12315
12316
12317
12318
12319
12320
12321
12322
12323
12324
12325
12326
12327
12328
12329
12330
12331
12332
12333
12334
12335
12336
12337
12338
12339
12340
12341
12342
12343
12344
12345
12346
12347
12348
12349
12350
12351
12352
12353
12354
12355
12356
12357
12358
12359
12360
12361
12362
12363
12364
12365
12366
12367
12368
12369
12370
12371
12372
12373
12374
12375
12376
12377
12378
12379
12380
12381
12382
12383
12384
12385
12386
12387
12388
12389
12390
12391
12392
12393
12394
12395
12396
12397
12398
12399
12400
12401
12402
12403
12404
12405
12406
12407
12408
12409
12410
12411
12412
12413
12414
12415
12416
12417
12418
12419
12420
12421
12422
12423
12424
12425
12426
12427
12428
12429
12430
12431
12432
12433
12434
12435
12436
12437
12438
12439
12440
12441
12442
12443
12444
12445
12446
12447
12448
12449
12450
12451
12452
12453
12454
12455
12456
12457
12458
12459
12460
12461
12462
12463
12464
12465
12466
12467
12468
12469
12470
12471
12472
12473
12474
12475
12476
12477
12478
12479
12480
12481
12482
12483
12484
12485
12486
12487
12488
12489
12490
12491
12492
12493
12494
12495
12496
12497
12498
12499
12500
12501
12502
12503
12504
12505
12506
12507
12508
12509
12510
12511
12512
12513
12514
12515
12516
12517
12518
12519
12520
12521
12522
12523
12524
12525
12526
12527
12528
12529
12530
12531
12532
12533
12534
12535
12536
12537
12538
12539
12540
12541
12542
12543
12544
12545
12546
12547
12548
12549
12550
12551
12552
12553
12554
12555
12556
12557
12558
12559
12560
12561
12562
12563
12564
12565
12566
12567
12568
12569
12570
12571
12572
12573
12574
12575
12576
12577
12578
12579
12580
12581
12582
12583
12584
12585
12586
12587
12588
12589
12590
12591
12592
12593
12594
12595
12596
12597
12598
12599
12600
12601
12602
12603
12604
12605
12606
12607
12608
12609
12610
12611
12612
12613
12614
12615
12616
12617
12618
12619
12620
12621
12622
12623
12624
12625
12626
12627
12628
12629
12630
12631
12632
12633
12634
12635
12636
12637
12638
12639
12640
12641
12642
12643
12644
12645
12646
12647
12648
12649
12650
12651
12652
12653
12654
12655
12656
12657
12658
12659
12660
12661
12662
12663
12664
12665
12666
12667
12668
12669
12670
12671
12672
12673
12674
12675
12676
12677
12678
12679
12680
12681
12682
12683
12684
12685
12686
12687
12688
12689
12690
12691
12692
12693
12694
12695
12696
12697
12698
12699
12700
12701
12702
12703
12704
12705
12706
12707
12708
12709
12710
12711
12712
12713
12714
12715
12716
12717
12718
12719
12720
12721
12722
12723
12724
12725
12726
12727
12728
12729
12730
12731
12732
12733
12734
12735
12736
12737
12738
12739
12740
12741
12742
12743
12744
12745
12746
12747
12748
12749
12750
12751
12752
12753
12754
12755
12756
12757
12758
12759
12760
12761
12762
12763
12764
12765
12766
12767
12768
12769
12770
12771
12772
12773
12774
12775
12776
12777
12778
12779
12780
12781
12782
12783
12784
12785
12786
12787
12788
12789
12790
12791
12792
12793
12794
12795
12796
12797
12798
12799
12800
12801
12802
12803
12804
12805
12806
12807
12808
12809
12810
12811
12812
12813
12814
12815
12816
12817
12818
12819
12820
12821
12822
12823
12824
12825
12826
12827
12828
12829
12830
12831
12832
12833
12834
12835
12836
12837
12838
12839
12840
12841
12842
12843
12844
12845
12846
12847
12848
12849
12850
12851
12852
12853
12854
12855
12856
12857
12858
12859
12860
12861
12862
12863
12864
12865
12866
12867
12868
12869
12870
12871
12872
12873
12874
12875
12876
12877
12878
12879
12880
12881
12882
12883
12884
12885
12886
12887
12888
12889
12890
12891
12892
12893
12894
12895
12896
12897
12898
12899
12900
12901
12902
12903
12904
12905
12906
12907
12908
12909
12910
12911
12912
12913
12914
12915
12916
12917
12918
12919
12920
12921
12922
12923
12924
12925
12926
12927
12928
12929
12930
12931
12932
12933
12934
12935
12936
12937
12938
12939
12940
12941
12942
12943
12944
12945
12946
12947
12948
12949
12950
12951
12952
12953
12954
12955
12956
12957
12958
12959
12960
12961
12962
12963
12964
12965
12966
12967
12968
12969
12970
12971
12972
12973
12974
12975
12976
12977
12978
12979
12980
12981
12982
12983
12984
12985
12986
12987
12988
12989
12990
12991
12992
12993
12994
12995
12996
12997
12998
12999
13000
13001
13002
13003
13004
13005
13006
13007
13008
13009
13010
13011
13012
13013
13014
13015
13016
13017
13018
13019
13020
13021
13022
13023
13024
13025
13026
13027
13028
13029
13030
13031
13032
13033
13034
13035
13036
13037
13038
13039
13040
13041
13042
13043
13044
13045
13046
13047
13048
13049
13050
13051
13052
13053
13054
13055
13056
13057
13058
13059
13060
13061
13062
13063
13064
13065
13066
13067
13068
13069
13070
13071
13072
13073
13074
13075
13076
13077
13078
13079
13080
13081
13082
13083
13084
13085
13086
13087
13088
13089
13090
13091
13092
13093
13094
13095
13096
13097
13098
13099
13100
13101
13102
13103
13104
13105
13106
13107
13108
13109
13110
13111
13112
13113
13114
13115
13116
13117
13118
13119
13120
13121
13122
13123
13124
13125
13126
13127
13128
13129
13130
13131
13132
13133
13134
13135
13136
13137
13138
13139
13140
13141
13142
13143
13144
13145
13146
13147
13148
13149
13150
13151
13152
13153
13154
13155
13156
13157
13158
13159
13160
13161
13162
13163
13164
13165
13166
13167
13168
13169
13170
13171
13172
13173
13174
13175
13176
13177
13178
13179
13180
13181
13182
13183
13184
13185
13186
13187
13188
13189
13190
13191
13192
13193
13194
13195
13196
13197
13198
13199
13200
13201
13202
13203
13204
13205
13206
13207
13208
13209
13210
13211
13212
13213
13214
13215
13216
13217
13218
13219
13220
13221
13222
13223
13224
13225
13226
13227
13228
13229
13230
13231
13232
13233
13234
13235
13236
13237
13238
13239
13240
13241
13242
13243
13244
13245
13246
13247
13248
13249
13250
13251
13252
13253
13254
13255
13256
13257
13258
13259
13260
13261
13262
13263
13264
13265
13266
13267
13268
13269
13270
13271
13272
13273
13274
13275
13276
13277
13278
13279
13280
13281
13282
13283
13284
13285
13286
13287
13288
13289
13290
13291
13292
13293
13294
13295
13296
13297
13298
13299
13300
13301
13302
13303
13304
13305
13306
13307
13308
13309
13310
13311
13312
13313
13314
13315
13316
13317
13318
13319
13320
13321
13322
13323
13324
13325
13326
13327
13328
13329
13330
13331
13332
13333
13334
13335
13336
13337
13338
13339
13340
13341
13342
13343
13344
13345
13346
13347
13348
13349
13350
13351
13352
13353
13354
13355
13356
13357
13358
13359
13360
13361
13362
13363
13364
13365
13366
13367
13368
13369
13370
13371
13372
13373
13374
13375
13376
13377
13378
13379
13380
13381
13382
13383
13384
13385
13386
13387
13388
13389
13390
13391
13392
13393
13394
13395
13396
13397
13398
13399
13400
13401
13402
13403
13404
13405
13406
13407
13408
13409
13410
13411
13412
13413
13414
13415
13416
13417
13418
13419
13420
13421
13422
13423
13424
13425
13426
13427
13428
13429
13430
13431
13432
13433
13434
13435
13436
13437
13438
13439
13440
13441
13442
13443
13444
13445
13446
13447
13448
13449
13450
13451
13452
13453
13454
13455
13456
13457
13458
13459
13460
13461
13462
13463
13464
13465
13466
13467
13468
13469
13470
13471
13472
13473
13474
13475
13476
13477
13478
13479
13480
13481
13482
13483
13484
13485
13486
13487
13488
13489
13490
13491
13492
13493
13494
13495
13496
13497
13498
13499
13500
13501
13502
13503
13504
13505
13506
13507
13508
13509
13510
13511
13512
13513
13514
13515
13516
13517
13518
13519
13520
13521
13522
13523
13524
13525
13526
13527
13528
13529
13530
13531
13532
13533
13534
13535
13536
13537
13538
13539
13540
13541
13542
13543
13544
13545
13546
13547
13548
13549
13550
13551
13552
13553
13554
13555
13556
13557
13558
13559
13560
13561
13562
13563
13564
13565
13566
13567
13568
13569
13570
13571
13572
13573
13574
13575
13576
13577
13578
13579
13580
13581
13582
13583
13584
13585
13586
13587
13588
13589
13590
13591
13592
13593
13594
13595
13596
13597
13598
13599
13600
13601
13602
13603
13604
13605
13606
13607
13608
13609
13610
13611
13612
13613
13614
13615
13616
13617
13618
13619
13620
13621
13622
13623
13624
13625
13626
13627
13628
13629
13630
13631
13632
13633
13634
13635
13636
13637
13638
13639
13640
13641
13642
13643
13644
13645
13646
13647
13648
13649
13650
13651
13652
13653
13654
13655
13656
13657
13658
13659
13660
13661
13662
13663
13664
13665
13666
13667
13668
13669
13670
13671
13672
13673
13674
13675
13676
13677
13678
13679
13680
13681
13682
13683
13684
13685
13686
13687
13688
13689
13690
13691
13692
13693
13694
13695
13696
13697
13698
13699
13700
13701
13702
13703
13704
13705
13706
13707
13708
13709
13710
13711
13712
13713
13714
13715
13716
13717
13718
13719
13720
13721
13722
13723
13724
13725
13726
13727
13728
13729
13730
13731
13732
13733
13734
13735
13736
13737
13738
13739
13740
13741
13742
13743
13744
13745
13746
13747
13748
13749
13750
13751
13752
13753
13754
13755
13756
13757
13758
13759
13760
13761
13762
13763
13764
13765
13766
13767
13768
13769
13770
13771
13772
13773
13774
13775
13776
13777
13778
13779
13780
13781
13782
13783
13784
13785
13786
13787
13788
13789
13790
13791
13792
13793
13794
13795
13796
13797
13798
13799
13800
13801
13802
13803
13804
13805
13806
13807
13808
13809
13810
13811
13812
13813
13814
13815
13816
13817
13818
13819
13820
13821
13822
13823
13824
13825
13826
13827
13828
13829
13830
13831
13832
13833
13834
13835
13836
13837
13838
13839
13840
13841
13842
13843
13844
13845
13846
13847
13848
13849
13850
13851
13852
13853
13854
13855
13856
13857
13858
13859
13860
13861
13862
13863
13864
13865
13866
13867
13868
13869
13870
13871
13872
13873
13874
13875
13876
13877
13878
13879
13880
13881
13882
13883
13884
13885
13886
13887
13888
13889
13890
13891
13892
13893
13894
13895
13896
13897
13898
13899
13900
13901
13902
13903
13904
13905
13906
13907
13908
13909
13910
13911
13912
13913
13914
13915
13916
13917
13918
13919
13920
13921
13922
13923
13924
13925
13926
13927
13928
13929
13930
13931
13932
13933
13934
13935
13936
13937
13938
13939
13940
13941
13942
13943
13944
13945
13946
13947
13948
13949
13950
13951
13952
13953
13954
13955
13956
13957
13958
13959
13960
13961
13962
13963
13964
13965
13966
13967
13968
13969
13970
13971
13972
13973
13974
13975
13976
13977
13978
13979
13980
13981
13982
13983
13984
13985
13986
13987
13988
13989
13990
13991
13992
13993
13994
13995
13996
13997
13998
13999
14000
14001
14002
14003
14004
14005
14006
14007
14008
14009
14010
14011
14012
14013
14014
14015
14016
14017
14018
14019
14020
14021
14022
14023
14024
14025
14026
14027
14028
14029
14030
14031
14032
14033
14034
14035
14036
14037
14038
14039
14040
14041
14042
14043
14044
14045
14046
14047
14048
14049
14050
14051
14052
14053
14054
14055
14056
14057
14058
14059
14060
14061
14062
14063
14064
14065
14066
14067
14068
14069
14070
14071
14072
14073
14074
14075
14076
14077
14078
14079
14080
14081
14082
14083
14084
14085
14086
14087
14088
14089
14090
14091
14092
14093
14094
14095
14096
14097
14098
14099
14100
14101
14102
14103
14104
14105
14106
14107
14108
14109
14110
14111
14112
14113
14114
14115
14116
14117
14118
14119
14120
14121
14122
14123
14124
14125
14126
14127
14128
14129
14130
14131
14132
14133
14134
14135
14136
14137
14138
14139
14140
14141
14142
14143
14144
14145
14146
14147
14148
14149
14150
14151
14152
14153
14154
14155
14156
14157
14158
14159
14160
14161
14162
14163
14164
14165
14166
14167
14168
14169
14170
14171
14172
14173
14174
14175
14176
14177
14178
14179
14180
14181
14182
14183
14184
14185
14186
14187
14188
14189
14190
14191
14192
14193
14194
14195
14196
14197
14198
14199
14200
14201
14202
14203
14204
14205
14206
14207
14208
14209
14210
14211
14212
14213
14214
14215
14216
14217
14218
14219
14220
14221
14222
14223
14224
14225
14226
14227
14228
14229
14230
14231
14232
14233
14234
14235
14236
14237
14238
14239
14240
14241
14242
14243
14244
14245
14246
14247
14248
14249
14250
14251
14252
14253
14254
14255
14256
14257
14258
14259
14260
14261
14262
14263
14264
14265
14266
14267
14268
14269
14270
14271
14272
14273
14274
14275
14276
14277
14278
14279
14280
14281
14282
14283
14284
14285
14286
14287
14288
14289
14290
14291
14292
14293
14294
14295
14296
14297
14298
14299
14300
14301
14302
14303
14304
14305
14306
14307
14308
14309
14310
14311
14312
14313
14314
14315
14316
14317
14318
14319
14320
14321
14322
14323
14324
14325
14326
14327
14328
14329
14330
14331
14332
14333
14334
14335
14336
14337
14338
14339
14340
14341
14342
14343
14344
14345
14346
14347
14348
14349
14350
14351
14352
14353
14354
14355
14356
14357
14358
14359
14360
14361
14362
14363
14364
14365
14366
14367
14368
14369
14370
14371
14372
14373
14374
14375
14376
14377
14378
14379
14380
14381
14382
14383
14384
14385
14386
14387
14388
14389
14390
14391
14392
14393
14394
14395
14396
14397
14398
14399
14400
14401
14402
14403
14404
14405
14406
14407
14408
14409
14410
14411
14412
14413
14414
14415
14416
14417
14418
14419
14420
14421
14422
14423
14424
14425
14426
14427
14428
14429
14430
14431
14432
14433
14434
14435
14436
14437
14438
14439
14440
14441
14442
14443
14444
14445
14446
14447
14448
14449
14450
14451
14452
14453
14454
14455
14456
14457
14458
14459
14460
14461
14462
14463
14464
14465
14466
14467
14468
14469
14470
14471
14472
14473
14474
14475
14476
14477
14478
14479
14480
14481
14482
14483
14484
14485
14486
14487
14488
14489
14490
14491
14492
14493
14494
14495
14496
14497
14498
14499
14500
14501
14502
14503
14504
14505
14506
14507
14508
14509
14510
14511
14512
14513
14514
14515
14516
14517
14518
14519
14520
14521
14522
14523
14524
14525
14526
14527
14528
14529
14530
14531
14532
14533
14534
14535
14536
14537
14538
14539
14540
14541
14542
14543
14544
14545
14546
14547
14548
14549
14550
14551
14552
14553
14554
14555
14556
14557
14558
14559
14560
14561
14562
14563
14564
14565
14566
14567
14568
14569
14570
14571
14572
14573
14574
14575
14576
14577
14578
14579
14580
14581
14582
14583
14584
14585
14586
14587
14588
14589
14590
14591
14592
14593
14594
14595
14596
14597
14598
14599
14600
14601
14602
14603
14604
14605
14606
14607
14608
14609
14610
14611
14612
14613
14614
14615
14616
14617
14618
14619
14620
14621
14622
14623
14624
14625
14626
14627
14628
14629
14630
14631
14632
14633
14634
14635
14636
14637
14638
14639
14640
14641
14642
14643
14644
14645
14646
14647
14648
14649
14650
14651
14652
14653
14654
14655
14656
14657
14658
14659
14660
14661
14662
14663
14664
14665
14666
14667
14668
14669
14670
14671
14672
14673
14674
14675
14676
14677
14678
14679
14680
14681
14682
14683
14684
14685
14686
14687
14688
14689
14690
14691
14692
14693
14694
14695
14696
14697
14698
14699
14700
14701
14702
14703
14704
14705
14706
14707
14708
14709
14710
14711
14712
14713
14714
14715
14716
14717
14718
14719
14720
14721
14722
14723
14724
14725
14726
14727
14728
14729
14730
14731
14732
14733
14734
14735
14736
14737
14738
14739
14740
14741
14742
14743
14744
14745
14746
14747
14748
14749
14750
14751
14752
14753
14754
14755
14756
14757
14758
14759
14760
14761
14762
14763
14764
14765
14766
14767
14768
14769
14770
14771
14772
14773
14774
14775
14776
14777
14778
14779
14780
14781
14782
14783
14784
14785
14786
14787
14788
14789
14790
14791
14792
14793
14794
14795
14796
14797
14798
14799
14800
14801
14802
14803
14804
14805
14806
14807
14808
14809
14810
14811
14812
14813
14814
14815
14816
14817
14818
14819
14820
14821
14822
14823
14824
14825
14826
14827
14828
14829
14830
14831
14832
14833
14834
14835
14836
14837
14838
14839
14840
14841
14842
14843
14844
14845
14846
14847
14848
14849
14850
14851
14852
14853
14854
14855
14856
14857
14858
14859
14860
14861
14862
14863
14864
14865
14866
14867
14868
14869
14870
14871
14872
14873
14874
14875
14876
14877
14878
14879
14880
14881
14882
14883
14884
14885
14886
14887
14888
14889
14890
14891
14892
14893
14894
14895
14896
14897
14898
14899
14900
14901
14902
14903
14904
14905
14906
14907
14908
14909
14910
14911
14912
14913
14914
14915
14916
14917
14918
14919
14920
14921
14922
14923
14924
14925
14926
14927
14928
14929
14930
14931
14932
14933
14934
14935
14936
14937
14938
14939
14940
14941
14942
14943
14944
14945
14946
14947
14948
14949
14950
14951
14952
14953
14954
14955
14956
14957
14958
14959
14960
14961
14962
14963
14964
14965
14966
14967
14968
14969
14970
14971
14972
14973
14974
14975
14976
14977
14978
14979
14980
14981
14982
14983
14984
14985
14986
14987
14988
14989
14990
14991
14992
14993
14994
14995
14996
14997
14998
14999
15000
15001
15002
15003
15004
15005
15006
15007
15008
15009
15010
15011
15012
15013
15014
15015
15016
15017
15018
15019
15020
15021
15022
15023
15024
15025
15026
15027
15028
15029
15030
15031
15032
15033
15034
15035
15036
15037
15038
15039
15040
15041
15042
15043
15044
15045
15046
15047
15048
15049
15050
15051
15052
15053
15054
15055
15056
15057
15058
15059
15060
15061
15062
15063
15064
15065
15066
15067
15068
15069
15070
15071
15072
15073
15074
15075
15076
15077
15078
15079
15080
15081
15082
15083
15084
15085
15086
15087
15088
15089
15090
15091
15092
15093
15094
15095
15096
15097
15098
15099
15100
15101
15102
15103
15104
15105
15106
15107
15108
15109
15110
15111
15112
15113
15114
15115
15116
15117
15118
15119
15120
15121
15122
15123
15124
15125
15126
15127
15128
15129
15130
15131
15132
15133
15134
15135
15136
15137
15138
15139
15140
15141
15142
15143
15144
15145
15146
15147
15148
15149
15150
15151
15152
15153
15154
15155
15156
15157
15158
15159
15160
15161
15162
15163
15164
15165
15166
15167
15168
15169
15170
15171
15172
15173
15174
15175
15176
15177
15178
15179
15180
15181
15182
15183
15184
15185
15186
15187
15188
15189
15190
15191
15192
15193
15194
15195
15196
15197
15198
15199
15200
15201
15202
15203
15204
15205
15206
15207
15208
15209
15210
15211
15212
15213
15214
15215
15216
15217
15218
15219
15220
15221
15222
15223
15224
15225
15226
15227
15228
15229
15230
15231
15232
15233
15234
15235
15236
15237
15238
15239
15240
15241
15242
15243
15244
15245
15246
15247
15248
15249
15250
15251
15252
15253
15254
15255
15256
15257
15258
15259
15260
15261
15262
15263
15264
15265
15266
15267
15268
15269
15270
15271
15272
15273
15274
15275
15276
15277
15278
15279
15280
15281
15282
15283
15284
15285
15286
15287
15288
15289
15290
15291
15292
15293
15294
15295
15296
15297
15298
15299
15300
15301
15302
15303
15304
15305
15306
15307
15308
15309
15310
15311
15312
15313
15314
15315
15316
15317
15318
15319
15320
15321
15322
15323
15324
15325
15326
15327
15328
15329
15330
15331
15332
15333
15334
15335
15336
15337
15338
15339
15340
15341
15342
15343
15344
15345
15346
15347
15348
15349
15350
15351
15352
15353
15354
15355
15356
15357
15358
15359
15360
15361
15362
15363
15364
15365
15366
15367
15368
15369
15370
15371
15372
15373
15374
15375
15376
15377
15378
15379
15380
15381
15382
15383
15384
15385
15386
15387
15388
15389
15390
15391
15392
15393
15394
15395
15396
15397
15398
15399
15400
15401
15402
15403
15404
15405
15406
15407
15408
15409
15410
15411
15412
15413
15414
15415
15416
15417
15418
15419
15420
15421
15422
15423
15424
15425
15426
15427
15428
15429
15430
15431
15432
15433
15434
15435
15436
15437
15438
15439
15440
15441
15442
15443
15444
15445
15446
15447
15448
15449
15450
15451
15452
15453
15454
15455
15456
15457
15458
15459
15460
15461
15462
15463
15464
15465
15466
15467
15468
15469
15470
15471
15472
15473
15474
15475
15476
15477
15478
15479
15480
15481
15482
15483
15484
15485
15486
15487
15488
15489
15490
15491
15492
15493
15494
15495
15496
15497
15498
15499
15500
15501
15502
15503
15504
15505
15506
15507
15508
15509
15510
15511
15512
15513
15514
15515
15516
15517
15518
15519
15520
15521
15522
15523
15524
15525
15526
15527
15528
15529
15530
15531
15532
15533
15534
15535
15536
15537
15538
15539
15540
15541
15542
15543
15544
15545
15546
15547
15548
15549
15550
15551
15552
15553
15554
15555
15556
15557
15558
15559
15560
15561
15562
15563
15564
15565
15566
15567
15568
15569
15570
15571
15572
15573
15574
15575
15576
15577
15578
15579
15580
15581
15582
15583
15584
15585
15586
15587
15588
15589
15590
15591
15592
15593
15594
15595
15596
15597
15598
15599
15600
15601
15602
15603
15604
15605
15606
15607
15608
15609
15610
15611
15612
15613
15614
15615
15616
15617
15618
15619
15620
15621
15622
15623
15624
15625
15626
15627
15628
15629
15630
15631
15632
15633
15634
15635
15636
15637
15638
15639
15640
15641
15642
15643
15644
15645
15646
15647
15648
15649
15650
15651
15652
15653
15654
15655
15656
15657
15658
15659
15660
15661
15662
15663
15664
15665
15666
15667
15668
15669
15670
15671
15672
15673
15674
15675
15676
15677
15678
15679
15680
15681
15682
15683
15684
15685
15686
15687
15688
15689
15690
15691
15692
15693
15694
15695
15696
15697
15698
15699
15700
15701
15702
15703
15704
15705
15706
15707
15708
15709
15710
15711
15712
15713
15714
15715
15716
15717
15718
15719
15720
15721
15722
15723
15724
15725
15726
15727
15728
15729
15730
15731
15732
15733
15734
15735
15736
15737
15738
15739
15740
15741
15742
15743
15744
15745
15746
15747
15748
15749
15750
15751
15752
15753
15754
15755
15756
15757
15758
15759
15760
15761
15762
15763
15764
15765
15766
15767
15768
15769
15770
15771
15772
15773
15774
15775
15776
15777
15778
15779
15780
15781
15782
15783
15784
15785
15786
15787
15788
15789
15790
15791
15792
15793
15794
15795
15796
15797
15798
15799
15800
15801
15802
15803
15804
15805
15806
15807
15808
15809
15810
15811
15812
15813
15814
15815
15816
15817
15818
15819
15820
15821
15822
15823
15824
15825
15826
15827
15828
15829
15830
15831
15832
15833
15834
15835
15836
15837
15838
15839
15840
15841
15842
15843
15844
15845
15846
15847
15848
15849
15850
15851
15852
15853
15854
15855
15856
15857
15858
15859
15860
15861
15862
15863
15864
15865
15866
15867
15868
15869
15870
15871
15872
15873
15874
15875
15876
15877
15878
15879
15880
15881
15882
15883
15884
15885
15886
15887
15888
15889
15890
15891
15892
15893
15894
15895
15896
15897
15898
15899
15900
15901
15902
15903
15904
15905
15906
15907
15908
15909
15910
15911
15912
15913
15914
15915
15916
15917
15918
15919
15920
15921
15922
15923
15924
15925
15926
15927
15928
15929
15930
15931
15932
15933
15934
15935
15936
15937
15938
15939
15940
15941
15942
15943
15944
15945
15946
15947
15948
15949
15950
15951
15952
15953
15954
15955
15956
15957
15958
15959
15960
15961
15962
15963
15964
15965
15966
15967
15968
15969
15970
15971
15972
15973
15974
15975
15976
15977
15978
15979
15980
15981
15982
15983
15984
15985
15986
15987
15988
15989
15990
15991
15992
15993
15994
15995
15996
15997
15998
15999
16000
16001
16002
16003
16004
16005
16006
16007
16008
16009
16010
16011
16012
16013
16014
16015
16016
16017
16018
16019
16020
16021
16022
16023
16024
16025
16026
16027
16028
16029
16030
16031
16032
16033
16034
16035
16036
16037
16038
16039
16040
16041
16042
16043
16044
16045
16046
16047
16048
16049
16050
16051
16052
16053
16054
16055
16056
16057
16058
16059
16060
16061
16062
16063
16064
16065
16066
16067
16068
16069
16070
16071
16072
16073
16074
16075
16076
16077
16078
16079
16080
16081
16082
16083
16084
16085
16086
16087
16088
16089
16090
16091
16092
16093
16094
16095
16096
16097
16098
16099
16100
16101
16102
16103
16104
16105
16106
16107
16108
16109
16110
16111
16112
16113
16114
16115
16116
16117
16118
16119
16120
16121
16122
16123
16124
16125
16126
16127
16128
16129
16130
16131
16132
16133
16134
16135
16136
16137
16138
16139
16140
16141
16142
16143
16144
16145
16146
16147
16148
16149
16150
16151
16152
16153
16154
16155
16156
16157
16158
16159
16160
16161
16162
16163
16164
16165
16166
16167
16168
16169
16170
16171
16172
16173
16174
16175
16176
16177
16178
16179
16180
16181
16182
16183
16184
16185
16186
16187
16188
16189
16190
16191
16192
16193
16194
16195
16196
16197
16198
16199
16200
16201
16202
16203
16204
16205
16206
16207
16208
16209
16210
16211
16212
16213
16214
16215
16216
16217
16218
16219
16220
16221
16222
16223
16224
16225
16226
16227
16228
16229
16230
16231
16232
16233
16234
16235
16236
16237
16238
16239
16240
16241
16242
16243
16244
16245
16246
16247
16248
16249
16250
16251
16252
16253
16254
16255
16256
16257
16258
16259
16260
16261
16262
16263
16264
16265
16266
16267
16268
16269
16270
16271
16272
16273
16274
16275
16276
16277
16278
16279
16280
16281
16282
16283
16284
16285
16286
16287
16288
16289
16290
16291
16292
16293
16294
16295
16296
16297
16298
16299
16300
16301
16302
16303
16304
16305
16306
16307
16308
16309
16310
16311
16312
16313
16314
16315
16316
16317
16318
16319
16320
16321
16322
16323
16324
16325
16326
16327
16328
16329
16330
16331
16332
16333
16334
16335
16336
16337
16338
16339
16340
16341
16342
16343
16344
16345
16346
16347
16348
16349
16350
16351
16352
16353
16354
16355
16356
16357
16358
16359
16360
16361
16362
16363
16364
16365
16366
16367
16368
16369
16370
16371
16372
16373
16374
16375
16376
16377
16378
16379
16380
16381
16382
16383
16384
16385
16386
16387
16388
16389
16390
16391
16392
16393
16394
16395
16396
16397
16398
16399
16400
16401
16402
16403
16404
16405
16406
16407
16408
16409
16410
16411
16412
16413
16414
16415
16416
16417
16418
16419
16420
16421
16422
16423
16424
16425
16426
16427
16428
16429
16430
16431
16432
16433
16434
16435
16436
16437
16438
16439
16440
16441
16442
16443
16444
16445
16446
16447
16448
16449
16450
16451
16452
16453
16454
16455
16456
16457
16458
16459
16460
16461
16462
16463
16464
16465
16466
16467
16468
16469
16470
16471
16472
16473
16474
16475
16476
16477
16478
16479
16480
16481
16482
16483
16484
16485
16486
16487
16488
16489
16490
16491
16492
16493
16494
16495
16496
16497
16498
16499
16500
16501
16502
16503
16504
16505
16506
16507
16508
16509
16510
16511
16512
16513
16514
16515
16516
16517
16518
16519
16520
16521
16522
16523
16524
16525
16526
16527
16528
16529
16530
16531
16532
16533
16534
16535
16536
16537
16538
16539
16540
16541
16542
16543
16544
16545
16546
16547
16548
16549
16550
16551
16552
16553
16554
16555
16556
16557
16558
16559
16560
16561
16562
16563
16564
16565
16566
16567
16568
16569
16570
16571
16572
16573
16574
16575
16576
16577
16578
16579
16580
16581
16582
16583
16584
16585
16586
16587
16588
16589
16590
16591
16592
16593
16594
16595
16596
16597
16598
16599
16600
16601
16602
16603
16604
16605
16606
16607
16608
16609
16610
16611
16612
16613
16614
16615
16616
16617
16618
16619
16620
16621
16622
16623
16624
16625
16626
16627
16628
16629
16630
16631
16632
16633
16634
16635
16636
16637
16638
16639
16640
16641
16642
16643
16644
16645
16646
16647
16648
16649
16650
16651
16652
16653
16654
16655
16656
16657
16658
16659
16660
16661
16662
16663
16664
16665
16666
16667
16668
16669
16670
16671
16672
16673
16674
16675
16676
16677
16678
16679
16680
16681
16682
16683
16684
16685
16686
16687
16688
16689
16690
16691
16692
16693
16694
16695
16696
16697
16698
16699
16700
16701
16702
16703
16704
16705
16706
16707
16708
16709
16710
16711
16712
16713
16714
16715
16716
16717
16718
16719
16720
16721
16722
16723
16724
16725
16726
16727
16728
16729
16730
16731
16732
16733
16734
16735
16736
16737
16738
16739
16740
16741
16742
16743
16744
16745
16746
16747
16748
16749
16750
16751
16752
16753
16754
16755
16756
16757
16758
16759
16760
16761
16762
16763
16764
16765
16766
16767
16768
16769
16770
16771
16772
16773
16774
16775
16776
16777
16778
16779
16780
16781
16782
16783
16784
16785
16786
16787
16788
16789
16790
16791
16792
16793
16794
16795
16796
16797
16798
16799
16800
16801
16802
16803
16804
16805
16806
16807
16808
16809
16810
16811
16812
16813
16814
16815
16816
16817
16818
16819
16820
16821
16822
16823
16824
16825
16826
16827
16828
16829
16830
16831
16832
16833
16834
16835
16836
16837
16838
16839
16840
16841
16842
16843
16844
16845
16846
16847
16848
16849
16850
16851
16852
16853
16854
16855
16856
16857
16858
16859
16860
16861
16862
16863
16864
16865
16866
16867
16868
16869
16870
16871
16872
16873
16874
16875
16876
16877
16878
16879
16880
16881
16882
16883
16884
16885
16886
16887
16888
16889
16890
16891
16892
16893
16894
16895
16896
16897
16898
16899
16900
16901
16902
16903
16904
16905
16906
16907
16908
16909
16910
16911
16912
16913
16914
16915
16916
16917
16918
16919
16920
16921
16922
16923
16924
16925
16926
16927
16928
16929
16930
16931
16932
16933
16934
16935
16936
16937
16938
16939
16940
16941
16942
16943
16944
16945
16946
16947
16948
16949
16950
16951
16952
16953
16954
16955
16956
16957
16958
16959
16960
16961
16962
16963
16964
16965
16966
16967
16968
16969
16970
16971
16972
16973
16974
16975
16976
16977
16978
16979
16980
16981
16982
16983
16984
16985
16986
16987
16988
16989
16990
16991
16992
16993
16994
16995
16996
16997
16998
16999
17000
17001
17002
17003
17004
17005
17006
17007
17008
17009
17010
17011
17012
17013
17014
17015
17016
17017
17018
17019
17020
17021
17022
17023
17024
17025
17026
17027
17028
17029
17030
17031
17032
17033
17034
17035
17036
17037
17038
17039
17040
17041
17042
17043
17044
17045
17046
17047
17048
17049
17050
17051
17052
17053
17054
17055
17056
17057
17058
17059
17060
17061
17062
17063
17064
17065
17066
17067
17068
17069
17070
17071
17072
17073
17074
17075
17076
17077
17078
17079
17080
17081
17082
17083
17084
17085
17086
17087
17088
17089
17090
17091
17092
17093
17094
17095
17096
17097
17098
17099
17100
17101
17102
17103
17104
17105
17106
17107
17108
17109
17110
17111
17112
17113
17114
17115
17116
17117
17118
17119
17120
17121
17122
17123
17124
17125
17126
17127
17128
17129
17130
17131
17132
17133
17134
17135
17136
17137
17138
17139
17140
17141
17142
17143
17144
17145
17146
17147
17148
17149
17150
17151
17152
17153
17154
17155
17156
17157
17158
17159
17160
17161
17162
17163
17164
17165
17166
17167
17168
17169
17170
17171
17172
17173
17174
17175
17176
17177
17178
17179
17180
17181
17182
17183
17184
17185
17186
17187
17188
17189
17190
17191
17192
17193
17194
17195
17196
17197
17198
17199
17200
17201
17202
17203
17204
17205
17206
17207
17208
17209
17210
17211
17212
17213
17214
17215
17216
17217
17218
17219
17220
17221
17222
17223
17224
17225
17226
17227
17228
17229
17230
17231
17232
17233
17234
17235
17236
17237
17238
17239
17240
17241
17242
17243
17244
17245
17246
17247
17248
17249
17250
17251
17252
17253
17254
17255
17256
17257
17258
17259
17260
17261
17262
17263
17264
17265
17266
17267
17268
17269
17270
17271
17272
17273
17274
17275
17276
17277
17278
17279
17280
17281
17282
17283
17284
17285
17286
17287
17288
17289
17290
17291
17292
17293
17294
17295
17296
17297
17298
17299
17300
17301
17302
17303
17304
17305
17306
17307
17308
17309
17310
17311
17312
17313
17314
17315
17316
17317
17318
17319
17320
17321
17322
17323
17324
17325
17326
17327
17328
17329
17330
17331
17332
17333
17334
17335
17336
17337
17338
17339
17340
17341
17342
17343
17344
17345
17346
17347
17348
17349
17350
17351
17352
17353
17354
17355
17356
17357
17358
17359
17360
17361
17362
17363
17364
17365
17366
17367
17368
17369
17370
17371
17372
17373
17374
17375
17376
17377
17378
17379
17380
17381
17382
17383
17384
17385
17386
17387
17388
17389
17390
17391
17392
17393
17394
17395
17396
17397
17398
17399
17400
17401
17402
17403
17404
17405
17406
17407
17408
17409
17410
17411
17412
17413
17414
17415
17416
17417
17418
17419
17420
17421
17422
17423
17424
17425
17426
17427
17428
17429
17430
17431
17432
17433
17434
17435
17436
17437
17438
17439
17440
17441
17442
17443
17444
17445
17446
17447
17448
17449
17450
17451
17452
17453
17454
17455
17456
17457
17458
17459
17460
17461
17462
17463
17464
17465
17466
17467
17468
17469
17470
17471
17472
17473
17474
17475
17476
17477
17478
17479
17480
17481
17482
17483
17484
17485
17486
17487
17488
17489
17490
17491
17492
17493
17494
17495
17496
17497
17498
17499
17500
17501
17502
17503
17504
17505
17506
17507
17508
17509
17510
17511
17512
17513
17514
17515
17516
17517
17518
17519
17520
17521
17522
17523
17524
17525
17526
17527
17528
17529
17530
17531
17532
17533
17534
17535
17536
17537
17538
17539
17540
17541
17542
17543
17544
17545
17546
17547
17548
17549
17550
17551
17552
17553
17554
17555
17556
17557
17558
17559
17560
17561
17562
17563
17564
17565
17566
17567
17568
17569
17570
17571
17572
17573
17574
17575
17576
17577
17578
17579
17580
17581
17582
17583
17584
17585
17586
17587
17588
17589
17590
17591
17592
17593
17594
17595
17596
17597
17598
17599
17600
17601
17602
17603
17604
17605
17606
17607
17608
17609
17610
17611
17612
17613
17614
17615
17616
17617
17618
17619
17620
17621
17622
17623
17624
17625
17626
17627
17628
17629
17630
17631
17632
17633
17634
17635
17636
17637
17638
17639
17640
17641
17642
17643
17644
17645
17646
17647
17648
17649
17650
17651
17652
17653
17654
17655
17656
17657
17658
17659
17660
17661
17662
17663
17664
17665
17666
17667
17668
17669
17670
17671
17672
17673
17674
17675
17676
17677
17678
17679
17680
17681
17682
17683
17684
17685
17686
17687
17688
17689
17690
17691
17692
17693
17694
17695
17696
17697
17698
17699
17700
17701
17702
17703
17704
17705
17706
17707
17708
17709
17710
17711
17712
17713
17714
17715
17716
17717
17718
17719
17720
17721
17722
17723
17724
17725
17726
17727
17728
17729
17730
17731
17732
17733
17734
17735
17736
17737
17738
17739
17740
17741
17742
17743
17744
17745
17746
17747
17748
17749
17750
17751
17752
17753
17754
17755
17756
17757
17758
17759
17760
17761
17762
17763
17764
17765
17766
17767
17768
17769
17770
17771
17772
17773
17774
17775
17776
17777
17778
17779
17780
17781
17782
17783
17784
17785
17786
17787
17788
17789
17790
17791
17792
17793
17794
17795
17796
17797
17798
17799
17800
17801
17802
17803
17804
17805
17806
17807
17808
17809
17810
17811
17812
17813
17814
17815
17816
17817
17818
17819
17820
17821
17822
17823
17824
17825
17826
17827
17828
17829
17830
17831
17832
17833
17834
17835
17836
17837
17838
17839
17840
17841
17842
17843
17844
17845
17846
17847
17848
17849
17850
17851
17852
17853
17854
17855
17856
17857
17858
17859
17860
17861
17862
17863
17864
17865
17866
17867
17868
17869
17870
17871
17872
17873
17874
17875
17876
17877
17878
17879
17880
17881
17882
17883
17884
17885
17886
17887
17888
17889
17890
17891
17892
17893
17894
17895
17896
17897
17898
17899
17900
17901
17902
17903
17904
17905
17906
17907
17908
17909
17910
17911
17912
17913
17914
17915
17916
17917
17918
17919
17920
17921
17922
17923
17924
17925
17926
17927
17928
17929
17930
17931
17932
17933
17934
17935
17936
17937
17938
17939
17940
17941
17942
17943
17944
17945
17946
17947
17948
17949
17950
17951
17952
17953
17954
17955
17956
17957
17958
17959
17960
17961
17962
17963
17964
17965
17966
17967
17968
17969
17970
17971
17972
17973
17974
17975
17976
17977
17978
17979
17980
17981
17982
17983
17984
17985
17986
17987
17988
17989
17990
17991
17992
17993
17994
17995
17996
17997
17998
17999
18000
18001
18002
18003
18004
18005
18006
18007
18008
18009
18010
18011
18012
18013
18014
18015
18016
18017
18018
18019
18020
18021
18022
18023
18024
18025
18026
18027
18028
18029
18030
18031
18032
18033
18034
18035
18036
18037
18038
18039
18040
18041
18042
18043
18044
18045
18046
18047
18048
18049
18050
18051
18052
18053
18054
18055
18056
18057
18058
18059
18060
18061
18062
18063
18064
18065
18066
18067
18068
18069
18070
18071
18072
18073
18074
18075
18076
18077
18078
18079
18080
18081
18082
18083
18084
18085
18086
18087
18088
18089
18090
18091
18092
18093
18094
18095
18096
18097
18098
18099
18100
18101
18102
18103
18104
18105
18106
18107
18108
18109
18110
18111
18112
18113
18114
18115
18116
18117
18118
18119
18120
18121
18122
18123
18124
18125
18126
18127
18128
18129
18130
18131
18132
18133
18134
18135
18136
18137
18138
18139
18140
18141
18142
18143
18144
18145
18146
18147
18148
18149
18150
18151
18152
18153
18154
18155
18156
18157
18158
18159
18160
18161
18162
18163
18164
18165
18166
18167
18168
18169
18170
18171
18172
18173
18174
18175
18176
18177
18178
18179
18180
18181
18182
18183
18184
18185
18186
18187
18188
18189
18190
18191
18192
18193
18194
18195
18196
18197
18198
18199
18200
18201
18202
18203
18204
18205
18206
18207
18208
18209
18210
18211
18212
18213
18214
18215
18216
18217
18218
18219
18220
18221
18222
18223
18224
18225
18226
18227
18228
18229
18230
18231
18232
18233
18234
18235
18236
18237
18238
18239
18240
18241
18242
18243
18244
18245
18246
18247
18248
18249
18250
18251
18252
18253
18254
18255
18256
18257
18258
18259
18260
18261
18262
18263
18264
18265
18266
18267
18268
18269
18270
18271
18272
18273
18274
18275
18276
18277
18278
18279
18280
18281
18282
18283
18284
18285
18286
18287
18288
18289
18290
18291
18292
18293
18294
18295
18296
18297
18298
18299
18300
18301
18302
18303
18304
18305
18306
18307
18308
18309
18310
18311
18312
18313
18314
18315
18316
18317
18318
18319
18320
18321
18322
18323
18324
18325
18326
18327
18328
18329
18330
18331
18332
18333
18334
18335
18336
18337
18338
18339
18340
18341
18342
18343
18344
18345
18346
18347
18348
18349
18350
18351
18352
18353
18354
18355
18356
18357
18358
18359
18360
18361
18362
18363
18364
18365
18366
18367
18368
18369
18370
18371
18372
18373
18374
18375
18376
18377
18378
18379
18380
18381
18382
18383
18384
18385
18386
18387
18388
18389
18390
18391
18392
18393
18394
18395
18396
18397
18398
18399
18400
18401
18402
18403
18404
18405
18406
18407
18408
18409
18410
18411
18412
18413
18414
18415
18416
18417
18418
18419
18420
18421
18422
18423
18424
18425
18426
18427
18428
18429
18430
18431
18432
18433
18434
18435
18436
18437
18438
18439
18440
18441
18442
18443
18444
18445
18446
18447
18448
18449
18450
18451
18452
18453
18454
18455
18456
18457
18458
18459
18460
18461
18462
18463
18464
18465
18466
18467
18468
18469
18470
18471
18472
18473
18474
18475
18476
18477
18478
18479
18480
18481
18482
18483
18484
18485
18486
18487
18488
18489
18490
18491
18492
18493
18494
18495
18496
18497
18498
18499
18500
18501
18502
18503
18504
18505
18506
18507
18508
18509
18510
18511
18512
18513
18514
18515
18516
18517
18518
18519
18520
18521
18522
18523
18524
18525
18526
18527
18528
18529
18530
18531
18532
18533
18534
18535
18536
18537
18538
18539
18540
18541
18542
18543
18544
18545
18546
18547
18548
18549
18550
18551
18552
18553
18554
18555
18556
18557
18558
18559
18560
18561
18562
18563
18564
18565
18566
18567
18568
18569
18570
18571
18572
18573
18574
18575
18576
18577
18578
18579
18580
18581
18582
18583
18584
18585
18586
18587
18588
18589
18590
18591
18592
18593
18594
18595
18596
18597
18598
18599
18600
18601
18602
18603
18604
18605
18606
18607
18608
18609
18610
18611
18612
18613
18614
18615
18616
18617
18618
18619
18620
18621
18622
18623
18624
18625
18626
18627
18628
18629
18630
18631
18632
18633
18634
18635
18636
18637
18638
18639
18640
18641
18642
18643
18644
18645
18646
18647
18648
18649
18650
18651
18652
18653
18654
18655
18656
18657
18658
18659
18660
18661
18662
18663
18664
18665
18666
18667
18668
18669
18670
18671
18672
18673
18674
18675
18676
18677
18678
18679
18680
18681
18682
18683
18684
18685
18686
18687
18688
18689
18690
18691
18692
18693
18694
18695
18696
18697
18698
18699
18700
18701
18702
18703
18704
18705
18706
18707
18708
18709
18710
18711
18712
18713
18714
18715
18716
18717
18718
18719
18720
18721
18722
18723
18724
18725
18726
18727
18728
18729
18730
18731
18732
18733
18734
18735
18736
18737
18738
18739
18740
18741
18742
18743
18744
18745
18746
18747
18748
18749
18750
18751
18752
18753
18754
18755
18756
18757
18758
18759
18760
18761
18762
18763
18764
18765
18766
18767
18768
18769
18770
18771
18772
18773
18774
18775
18776
18777
18778
18779
18780
18781
18782
18783
18784
18785
18786
18787
18788
18789
18790
18791
18792
18793
18794
18795
18796
18797
18798
18799
18800
18801
18802
18803
18804
18805
18806
18807
18808
18809
18810
18811
18812
18813
18814
18815
18816
18817
18818
18819
18820
18821
18822
18823
18824
18825
18826
18827
18828
18829
18830
18831
18832
18833
18834
18835
18836
18837
18838
18839
18840
18841
18842
18843
18844
18845
18846
18847
18848
18849
18850
18851
18852
18853
18854
18855
18856
18857
18858
18859
18860
18861
18862
18863
18864
18865
18866
18867
18868
18869
18870
18871
18872
18873
18874
18875
18876
18877
18878
18879
18880
18881
18882
18883
18884
18885
18886
18887
18888
18889
18890
18891
18892
18893
18894
18895
18896
18897
18898
18899
18900
18901
18902
18903
18904
18905
18906
18907
18908
18909
18910
18911
18912
18913
18914
18915
18916
18917
18918
18919
18920
18921
18922
18923
18924
18925
18926
18927
18928
18929
18930
18931
18932
18933
18934
18935
18936
18937
18938
18939
18940
18941
18942
18943
18944
18945
18946
18947
18948
18949
18950
18951
18952
18953
18954
18955
18956
18957
18958
18959
18960
18961
18962
18963
18964
18965
18966
18967
18968
18969
18970
18971
18972
18973
18974
18975
18976
18977
18978
18979
18980
18981
18982
18983
18984
18985
18986
18987
18988
18989
18990
18991
18992
18993
18994
18995
18996
18997
18998
18999
19000
19001
19002
19003
19004
19005
19006
19007
19008
19009
19010
19011
19012
19013
19014
19015
19016
19017
19018
19019
19020
19021
19022
19023
19024
19025
19026
19027
19028
19029
19030
19031
19032
19033
19034
19035
19036
19037
19038
19039
19040
19041
19042
19043
19044
19045
19046
19047
19048
19049
19050
19051
19052
19053
19054
19055
19056
19057
19058
19059
19060
19061
19062
19063
19064
19065
19066
19067
19068
19069
19070
19071
19072
19073
19074
19075
19076
19077
19078
19079
19080
19081
19082
19083
19084
19085
19086
19087
19088
19089
19090
19091
19092
19093
19094
19095
19096
19097
19098
19099
19100
19101
19102
19103
19104
19105
19106
19107
19108
19109
19110
19111
19112
19113
19114
19115
19116
19117
19118
19119
19120
19121
19122
19123
19124
19125
19126
19127
19128
19129
19130
19131
19132
19133
19134
19135
19136
19137
19138
19139
19140
19141
19142
19143
19144
19145
19146
19147
19148
19149
19150
19151
19152
19153
19154
19155
19156
19157
19158
19159
19160
19161
19162
19163
19164
19165
19166
19167
19168
19169
19170
19171
19172
19173
19174
19175
19176
19177
19178
19179
19180
19181
19182
19183
19184
19185
19186
19187
19188
19189
19190
19191
19192
19193
19194
19195
19196
19197
19198
19199
19200
19201
19202
19203
19204
19205
19206
19207
19208
19209
19210
19211
19212
19213
19214
19215
19216
19217
19218
19219
19220
19221
19222
19223
19224
19225
19226
19227
19228
19229
19230
19231
19232
19233
19234
19235
19236
19237
19238
19239
19240
19241
19242
19243
19244
19245
19246
19247
19248
19249
19250
19251
19252
19253
19254
19255
19256
19257
19258
19259
19260
19261
19262
19263
19264
19265
19266
19267
19268
19269
19270
19271
19272
19273
19274
19275
19276
19277
19278
19279
19280
19281
19282
19283
19284
19285
19286
19287
19288
19289
19290
19291
19292
19293
19294
19295
19296
19297
19298
19299
19300
19301
19302
19303
19304
19305
19306
19307
19308
19309
19310
19311
19312
19313
19314
19315
19316
19317
19318
19319
19320
19321
19322
19323
19324
19325
19326
19327
19328
19329
19330
19331
19332
19333
19334
19335
19336
19337
19338
19339
19340
19341
19342
19343
19344
19345
19346
19347
19348
19349
19350
19351
19352
19353
19354
19355
19356
19357
19358
19359
19360
19361
19362
19363
19364
19365
19366
19367
19368
19369
19370
19371
19372
19373
19374
19375
19376
19377
19378
19379
19380
19381
19382
19383
19384
19385
19386
19387
19388
19389
19390
19391
19392
19393
19394
19395
19396
19397
19398
19399
19400
19401
19402
19403
19404
19405
19406
19407
19408
19409
19410
19411
19412
19413
19414
19415
19416
19417
19418
19419
19420
19421
19422
19423
19424
19425
19426
19427
19428
19429
19430
19431
19432
19433
19434
19435
19436
19437
19438
19439
19440
19441
19442
19443
19444
19445
19446
19447
19448
19449
19450
19451
19452
19453
19454
19455
19456
19457
19458
19459
19460
19461
19462
19463
19464
19465
19466
19467
19468
19469
19470
19471
19472
19473
19474
19475
19476
19477
19478
19479
19480
19481
19482
19483
19484
19485
19486
19487
19488
19489
19490
19491
19492
19493
19494
19495
19496
19497
19498
19499
19500
19501
19502
19503
19504
19505
19506
19507
19508
19509
19510
19511
19512
19513
19514
19515
19516
19517
19518
19519
19520
19521
19522
19523
19524
19525
19526
19527
19528
19529
19530
19531
19532
19533
19534
19535
19536
19537
19538
19539
19540
19541
19542
19543
19544
19545
19546
19547
19548
19549
19550
19551
19552
19553
19554
19555
19556
19557
19558
19559
19560
19561
19562
19563
19564
19565
19566
19567
19568
19569
19570
19571
19572
19573
19574
19575
19576
19577
19578
19579
19580
19581
19582
19583
19584
19585
19586
19587
19588
19589
19590
19591
19592
19593
19594
19595
19596
19597
19598
19599
19600
19601
19602
19603
19604
19605
19606
19607
19608
19609
19610
19611
19612
19613
19614
19615
19616
19617
19618
19619
19620
19621
19622
19623
19624
19625
19626
19627
19628
19629
19630
19631
19632
19633
19634
19635
19636
19637
19638
19639
19640
19641
19642
19643
19644
19645
19646
19647
19648
19649
19650
19651
19652
19653
19654
19655
19656
19657
19658
19659
19660
19661
19662
19663
19664
19665
19666
19667
19668
19669
19670
19671
19672
19673
19674
19675
19676
19677
19678
19679
19680
19681
19682
19683
19684
19685
19686
19687
19688
19689
19690
19691
19692
19693
19694
19695
19696
19697
19698
19699
19700
19701
19702
19703
19704
19705
19706
19707
19708
19709
19710
19711
19712
19713
19714
19715
19716
19717
19718
19719
19720
19721
19722
19723
19724
19725
19726
19727
19728
19729
19730
19731
19732
19733
19734
19735
19736
19737
19738
19739
19740
19741
19742
19743
19744
19745
19746
19747
19748
19749
19750
19751
19752
19753
19754
19755
19756
19757
19758
19759
19760
19761
19762
19763
19764
19765
19766
19767
19768
19769
19770
19771
19772
19773
19774
19775
19776
19777
19778
19779
19780
19781
19782
19783
19784
19785
19786
19787
19788
19789
19790
19791
19792
19793
19794
19795
19796
19797
19798
19799
19800
19801
19802
19803
19804
19805
19806
19807
19808
19809
19810
19811
19812
19813
19814
19815
19816
19817
19818
19819
19820
19821
19822
19823
19824
19825
19826
19827
19828
19829
19830
19831
19832
19833
19834
19835
19836
19837
19838
19839
19840
19841
19842
19843
19844
19845
19846
19847
19848
19849
19850
19851
19852
19853
19854
19855
19856
19857
19858
19859
19860
19861
19862
19863
19864
19865
19866
19867
19868
19869
19870
19871
19872
19873
19874
19875
19876
19877
19878
19879
19880
19881
19882
19883
19884
19885
19886
19887
19888
19889
19890
19891
19892
19893
19894
19895
19896
19897
19898
19899
19900
19901
19902
19903
19904
19905
19906
19907
19908
19909
19910
19911
19912
19913
19914
19915
19916
19917
19918
19919
19920
19921
19922
19923
19924
19925
19926
19927
19928
19929
19930
19931
19932
19933
19934
19935
19936
19937
19938
19939
19940
19941
19942
19943
19944
19945
19946
19947
19948
19949
19950
19951
19952
19953
19954
19955
19956
19957
19958
19959
19960
19961
19962
19963
19964
19965
19966
19967
19968
19969
19970
19971
19972
19973
19974
19975
19976
19977
19978
19979
19980
19981
19982
19983
19984
19985
19986
19987
19988
19989
19990
19991
19992
19993
19994
19995
19996
19997
19998
19999
20000
20001
20002
20003
20004
20005
20006
20007
20008
20009
20010
20011
20012
20013
20014
20015
20016
20017
20018
20019
20020
20021
20022
20023
20024
20025
20026
20027
20028
20029
20030
20031
20032
20033
20034
20035
20036
20037
20038
20039
20040
20041
20042
20043
20044
20045
20046
20047
20048
20049
20050
20051
20052
20053
20054
20055
20056
20057
20058
20059
20060
20061
20062
20063
20064
20065
20066
20067
20068
20069
20070
20071
20072
20073
20074
20075
20076
20077
20078
20079
20080
20081
20082
20083
20084
20085
20086
20087
20088
20089
20090
20091
20092
20093
20094
20095
20096
20097
20098
20099
20100
20101
20102
20103
20104
20105
20106
20107
20108
20109
20110
20111
20112
20113
20114
20115
20116
20117
20118
20119
20120
20121
20122
20123
20124
20125
20126
20127
20128
20129
20130
20131
20132
20133
20134
20135
20136
20137
20138
20139
20140
20141
20142
20143
20144
20145
20146
20147
20148
20149
20150
20151
20152
20153
20154
20155
20156
20157
20158
20159
20160
20161
20162
20163
20164
20165
20166
20167
20168
20169
20170
20171
20172
20173
20174
20175
20176
20177
20178
20179
20180
20181
20182
20183
20184
20185
20186
20187
20188
20189
20190
20191
20192
20193
20194
20195
20196
20197
20198
20199
20200
20201
20202
20203
20204
20205
20206
20207
20208
20209
20210
20211
20212
20213
20214
20215
20216
20217
20218
20219
20220
20221
20222
20223
20224
20225
20226
20227
20228
20229
20230
20231
20232
20233
20234
20235
20236
20237
20238
20239
20240
20241
20242
20243
20244
20245
20246
20247
20248
20249
20250
20251
20252
20253
20254
20255
20256
20257
20258
20259
20260
20261
20262
20263
20264
20265
20266
20267
20268
20269
20270
20271
20272
20273
20274
20275
20276
20277
20278
20279
20280
20281
20282
20283
20284
20285
20286
20287
20288
20289
20290
20291
20292
20293
20294
20295
20296
20297
20298
20299
20300
20301
20302
20303
20304
20305
20306
20307
20308
20309
20310
20311
20312
20313
20314
20315
20316
20317
20318
20319
20320
20321
20322
20323
20324
20325
20326
20327
20328
20329
20330
20331
20332
20333
20334
20335
20336
20337
20338
20339
20340
20341
20342
20343
20344
20345
20346
20347
20348
20349
20350
20351
20352
20353
20354
20355
20356
20357
20358
20359
20360
20361
20362
20363
20364
20365
20366
20367
20368
20369
20370
20371
20372
20373
20374
20375
20376
20377
20378
20379
20380
20381
20382
20383
20384
20385
20386
20387
20388
20389
20390
20391
20392
20393
20394
20395
20396
20397
20398
20399
20400
20401
20402
20403
20404
20405
20406
20407
20408
20409
20410
20411
20412
20413
20414
20415
20416
20417
20418
20419
20420
20421
20422
20423
20424
20425
20426
20427
20428
20429
20430
20431
20432
20433
20434
20435
20436
20437
20438
20439
20440
20441
20442
20443
20444
20445
20446
20447
20448
20449
20450
20451
20452
20453
20454
20455
20456
20457
20458
20459
20460
20461
20462
20463
20464
20465
20466
20467
20468
20469
20470
20471
20472
20473
20474
20475
20476
20477
20478
20479
20480
20481
20482
20483
20484
20485
20486
20487
20488
20489
20490
20491
20492
20493
20494
20495
20496
20497
20498
20499
20500
20501
20502
20503
20504
20505
20506
20507
20508
20509
20510
20511
20512
20513
20514
20515
20516
20517
20518
20519
20520
20521
20522
20523
20524
20525
20526
20527
20528
20529
20530
20531
20532
20533
20534
20535
20536
20537
20538
20539
20540
20541
20542
20543
20544
20545
20546
20547
20548
20549
20550
20551
20552
20553
20554
20555
20556
20557
20558
20559
20560
20561
20562
20563
20564
20565
20566
20567
20568
20569
20570
20571
20572
20573
20574
20575
20576
20577
20578
20579
20580
20581
20582
20583
20584
20585
20586
20587
20588
20589
20590
20591
20592
20593
20594
20595
20596
20597
20598
20599
20600
20601
20602
20603
20604
20605
20606
20607
20608
20609
20610
20611
20612
20613
20614
20615
20616
20617
20618
20619
20620
20621
20622
20623
20624
20625
20626
20627
20628
20629
20630
20631
20632
20633
20634
20635
20636
20637
20638
20639
20640
20641
20642
20643
20644
20645
20646
20647
20648
20649
20650
20651
20652
20653
20654
20655
20656
20657
20658
20659
20660
20661
20662
20663
20664
20665
20666
20667
20668
20669
20670
20671
20672
20673
20674
20675
20676
20677
20678
20679
20680
20681
20682
20683
20684
20685
20686
20687
20688
20689
20690
20691
20692
20693
20694
20695
20696
20697
20698
20699
20700
20701
20702
20703
20704
20705
20706
20707
20708
20709
20710
20711
20712
20713
20714
20715
20716
20717
20718
20719
20720
20721
20722
20723
20724
20725
20726
20727
20728
20729
20730
20731
20732
20733
20734
20735
20736
20737
20738
20739
20740
20741
20742
20743
20744
20745
20746
20747
20748
20749
20750
20751
20752
20753
20754
20755
20756
20757
20758
20759
20760
20761
20762
20763
20764
20765
20766
20767
20768
20769
20770
20771
20772
20773
20774
20775
20776
20777
20778
20779
20780
20781
20782
20783
20784
20785
20786
20787
20788
20789
20790
20791
20792
20793
20794
20795
20796
20797
20798
20799
20800
20801
20802
20803
20804
20805
20806
20807
20808
20809
20810
20811
20812
20813
20814
20815
20816
20817
20818
20819
20820
20821
20822
20823
20824
20825
20826
20827
20828
20829
20830
20831
20832
20833
20834
20835
20836
20837
20838
20839
20840
20841
20842
20843
20844
20845
20846
20847
20848
20849
20850
20851
20852
20853
20854
20855
20856
20857
20858
20859
20860
20861
20862
20863
20864
20865
20866
20867
20868
20869
20870
20871
20872
20873
20874
20875
20876
20877
20878
20879
20880
20881
20882
20883
20884
20885
20886
20887
20888
20889
20890
20891
20892
20893
20894
20895
20896
20897
20898
20899
20900
20901
20902
20903
20904
20905
20906
20907
20908
20909
20910
20911
20912
20913
20914
20915
20916
20917
20918
20919
20920
20921
20922
20923
20924
20925
20926
20927
20928
20929
20930
20931
20932
20933
20934
20935
20936
20937
20938
20939
20940
20941
20942
20943
20944
20945
20946
20947
20948
20949
20950
20951
20952
20953
20954
20955
20956
20957
20958
20959
20960
20961
20962
20963
20964
20965
20966
20967
20968
20969
20970
20971
20972
20973
20974
20975
20976
20977
20978
20979
20980
20981
20982
20983
20984
20985
20986
20987
20988
20989
20990
20991
20992
20993
20994
20995
20996
20997
20998
20999
21000
21001
21002
21003
21004
21005
21006
21007
21008
21009
21010
21011
21012
21013
21014
21015
21016
21017
21018
21019
21020
21021
21022
21023
21024
21025
21026
21027
21028
21029
21030
21031
21032
21033
21034
21035
21036
21037
21038
21039
21040
21041
21042
21043
21044
21045
21046
21047
21048
21049
21050
21051
21052
21053
21054
21055

 
;;; GNU Guix --- Functional package management for GNU
;;; Copyright © 2015, 2016, 2017, 2018, 2019, 2020 Ricardo Wurmus <rekado@elephly.net>
;;; Copyright © 2015 Andreas Enge <andreas@enge.fr>
;;; Copyright © 2016, 2017 Ben Woodcroft <donttrustben@gmail.com>
;;; Copyright © 2016, 2017, 2018 Roel Janssen <roel@gnu.org>
;;; Copyright © 2017, 2018, 2019, 2020 Tobias Geerinckx-Rice <me@tobias.gr>
;;; Copyright © 2017 Raoul Bonnal <ilpuccio.febo@gmail.com>
;;; Copyright © 2018 Vijayalakshmi Vedantham <vijimay12@gmail.com>
;;; Copyright © 2018 Sahithi Yarlagadda <sahi@swecha.net>
;;; Copyright © 2018 Sandeep Subramanian <sandeepsubramanian94@gmail.com>
;;; Copyright © 2018 Charlie Ritter <chewzeirta@posteo.net>
;;; Copyright © 2018 Konrad Hinsen <konrad.hinsen@fastmail.net>
;;; Copyright © 2018, 2020 Mădălin Ionel Patrașcu <madalinionel.patrascu@mdc-berlin.de>
;;; Copyright © 2018 Laura Lazzati <laura.lazzati.15@gmail.com>
;;; Copyright © 2018 Leo Famulari <leo@famulari.name>
;;; Copyright © 2018 Marius Bakke <mbakke@fastmail.com>
;;; Copyright © 2018 Eric Brown <brown@fastmail.com>
;;; Copyright © 2018, 2019 Brett Gilio <brettg@gnu.org>
;;; Copyright © 2019 Nicolò Balzarotti <anothersms@gmail.com>
;;; Copyright © 2019 Wiktor Żelazny <wzelazny@vurv.cz>
;;; Copyright © 2020 Todor Kondić <tk.code@protonmail.com>
;;; Copyright © 2020 Danjela Lura <danielaluraa@gmail.com>
;;;
;;; This file is part of GNU Guix.
;;;
;;; GNU Guix is free software; you can redistribute it and/or modify it
;;; under the terms of the GNU General Public License as published by
;;; the Free Software Foundation; either version 3 of the License, or (at
;;; your option) any later version.
;;;
;;; GNU Guix is distributed in the hope that it will be useful, but
;;; WITHOUT ANY WARRANTY; without even the implied warranty of
;;; MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
;;; GNU General Public License for more details.
;;;
;;; You should have received a copy of the GNU General Public License
;;; along with GNU Guix.  If not, see <http://www.gnu.org/licenses/>.

(define-module (gnu packages cran)
  #:use-module ((guix licenses) #:prefix license:)
  #:use-module (guix packages)
  #:use-module (guix download)
  #:use-module (guix git-download)
  #:use-module (guix utils)
  #:use-module (guix build-system r)
  #:use-module (gnu packages algebra)
  #:use-module (gnu packages autotools)
  #:use-module (gnu packages base)
  #:use-module (gnu packages bioinformatics)
  #:use-module (gnu packages c)
  #:use-module (gnu packages compression)
  #:use-module (gnu packages curl)
  #:use-module (gnu packages databases)
  #:use-module (gnu packages fontutils)
  #:use-module (gnu packages gcc)
  #:use-module (gnu packages geo)
  #:use-module (gnu packages ghostscript)
  #:use-module (gnu packages gl)
  #:use-module (gnu packages gnome)
  #:use-module (gnu packages graph)
  #:use-module (gnu packages gtk)
  #:use-module (gnu packages haskell-xyz)
  #:use-module (gnu packages icu4c)
  #:use-module (gnu packages image)
  #:use-module (gnu packages imagemagick)
  #:use-module (gnu packages java)
  #:use-module (gnu packages javascript)
  #:use-module (gnu packages lisp-xyz)
  #:use-module (gnu packages machine-learning)
  #:use-module (gnu packages maths)
  #:use-module (gnu packages mpi)
  #:use-module (gnu packages multiprecision)
  #:use-module (gnu packages networking)
  #:use-module (gnu packages pcre)
  #:use-module (gnu packages perl)
  #:use-module (gnu packages pkg-config)
  #:use-module (gnu packages python)
  #:use-module (gnu packages python-xyz)
  #:use-module (gnu packages statistics)
  #:use-module (gnu packages tcl)
  #:use-module (gnu packages tls)
  #:use-module (gnu packages web)
  #:use-module (gnu packages xorg))

(define-public r-clipr
  (package
    (name "r-clipr")
    (version "0.7.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "clipr" version))
       (sha256
        (base32
         "1qn2p13d0c1bpqss6mv9hk60980rzhznfqpyaf5x0fy65svy9903"))))
    (build-system r-build-system)
    (home-page "https://github.com/mdlincoln/clipr")
    (synopsis "Read and write from the system clipboard")
    (description
     "This package provides simple utility functions to read from and write to
the system clipboards.")
    (license license:gpl3)))

(define-public r-oenb
  (package
    (name "r-oenb")
    (version "0.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "oenb" version))
       (sha256
        (base32
         "1x1jlqp6r27c4gb7wafzpmh5rq6yq61a2d395r5lsmv2g5jb4biz"))))
    (properties `((upstream-name . "oenb")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-xml" ,r-xml)))
    (native-inputs `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/franzmohr/oenb")
    (synopsis "Tools for the OeNB Data Web Service")
    (description
     "Tools to access data from the data web service of the
@acronym{OeNB, Oesterreichische Nationalbank},
@url{https://www.oenb.at/en/Statistics/User-Defined-Tables/webservice.html}.")
    (license license:gpl2+)))

(define-public r-scales
  (package
    (name "r-scales")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "scales" version))
       (sha256
        (base32 "00rdbfj5mwc3kr8pskidn3n2zkp4ms6cx36xazz54pxw3pysdr0y"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-farver" ,r-farver)
       ("r-labeling" ,r-labeling)
       ("r-lifecycle" ,r-lifecycle)
       ("r-munsell" ,r-munsell)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-r6" ,r-r6)
       ("r-viridislite" ,r-viridislite)))
    (home-page "https://github.com/hadley/scales")
    (synopsis "Scale functions for visualization")
    (description
     "This package provides graphical scales that map data to aesthetics, and
provides methods for automatically determining breaks and labels for axes and
legends.")
    (license license:expat)))

(define-public r-pheatmap
  (package
    (name "r-pheatmap")
    (version "1.0.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pheatmap" version))
       (sha256
        (base32
         "1hdh74az3vyzz6dqa311rhxdm74n46lyr03p862kn80p0kp9d7ap"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gtable" ,r-gtable)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-scales" ,r-scales)))
    (home-page "https://cran.r-project.org/web/packages/pheatmap")
    (synopsis "Pretty heatmaps")
    (description
     "This package provides an implementation of heatmaps that offers more
control over dimensions and appearance.")
    (license license:gpl2+)))

(define-public r-ellipsis
  (package
    (name "r-ellipsis")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ellipsis" version))
       (sha256
        (base32
         "01z9gq311nzwv3a0sa49jhm5ylqd59srip4vjkrf23hzgb5i9y0b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rlang" ,r-rlang)))
    (home-page "https://github.com/hadley/ellipsis")
    (synopsis "Tools for working with additional arguments")
    (description
     "In S3 generics, it's useful to take @code{...} so that methods can have
additional arguments.  But this flexibility comes at a cost: misspelled
arguments will be silently ignored.  The @code{ellipsis} package is an
experiment that allows a generic to warn if any arguments passed in @code{...}
are not used.")
    (license license:gpl3)))

(define-public r-grr
  (package
    (name "r-grr")
    (version "0.9.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "grr" version))
       (sha256
        (base32
         "0arbcgrvhkwb5xk4nry1ffg2qj0v8ivhjghdr505ib4357g0c9i9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/grr")
    (synopsis "Alternative implementations of base R functions")
    (description
     "This package provides alternative implementations of some base R
functions, including @code{sort}, @code{order}, and @code{match}.  The
functions are simplified but can be faster or have other advantages.")
    (license license:gpl3)))

(define-public r-matrix-utils
  (package
    (name "r-matrix-utils")
    (version "0.9.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Matrix.utils" version))
       (sha256
        (base32
         "0a5fq1scykqk0kc9j051j6fix6j2dqwz5wbgb0amaxsiywz9vigb"))))
    (properties `((upstream-name . "Matrix.utils")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-grr" ,r-grr)
       ("r-matrix" ,r-matrix)))
    (home-page "https://github.com/cvarrichio/Matrix.utils")
    (synopsis
     "Data.frame-Like Operations on Sparse and Dense Matrix Objects")
    (description
     "This package implements data manipulation methods such as @code{cast},
@code{aggregate}, and @code{merge}/@code{join} for Matrix and Matrix-like
objects.")
    (license license:gpl3)))

(define-public r-sys
  (package
    (name "r-sys")
    (version "3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sys" version))
       (sha256
        (base32
         "14wvy46i2iz9jn7lj3cvifmps932s3395wq681hniva0f8m7q8d6"))))
    (build-system r-build-system)
    (home-page "https://github.com/jeroen/sys")
    (synopsis "Powerful and reliable tools for running system commands in R")
    (description
     "This package provides drop-in replacements for the base @code{system2()}
function with fine control and consistent behavior across platforms.  It
supports clean interruption, timeout, background tasks, and streaming STDIN /
STDOUT / STDERR over binary or text connections.  The package also provides
functions for evaluating expressions inside a temporary fork.  Such
evaluations have no side effects on the main R process, and support reliable
interrupts and timeouts.  This provides the basis for a sandboxing
mechanism.")
    (license license:expat)))

(define-public r-askpass
  (package
    (name "r-askpass")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "askpass" version))
       (sha256
        (base32
         "07q0ik8jzk44vpwh48rr3fnpd7dzsdhjjsl4l850rffv3dyq4h6v"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-sys" ,r-sys)))
    (home-page "https://github.com/jeroen/askpass")
    (synopsis "Safe password entry for R")
    (description
     "This package provides cross-platform utilities for prompting the user
for credentials or a passphrase, for example to authenticate with a server or
read a protected key.")
    (license license:expat)))

(define-public r-vegan
  (package
    (name "r-vegan")
    (version "2.5-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "vegan" version))
       (sha256
        (base32
         "0g60rgn1i7wqf9pf5m1yki1m45gcp7i5hmjic0ci0f6vng70mh5k"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (propagated-inputs
     `(("r-cluster" ,r-cluster)
       ("r-knitr" ,r-knitr)             ; needed for vignettes
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-mgcv" ,r-mgcv)
       ("r-permute" ,r-permute)))
    (home-page "https://cran.r-project.org/web/packages/vegan")
    (synopsis "Functions for community ecology")
    (description
     "The vegan package provides tools for descriptive community ecology.  It
has most basic functions of diversity analysis, community ordination and
dissimilarity analysis.  Most of its multivariate tools can be used for other
data types as well.")
    (license license:gpl2+)))

(define-public r-tidyverse
  (package
    (name "r-tidyverse")
    (version "1.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tidyverse" version))
       (sha256
        (base32
         "02gyys08qv2v4cl2d66gml4d31ipxay0iyfwwksvxyclx60wp2kd"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-broom" ,r-broom)
       ("r-cli" ,r-cli)
       ("r-crayon" ,r-crayon)
       ("r-dbplyr" ,r-dbplyr)
       ("r-dplyr" ,r-dplyr)
       ("r-forcats" ,r-forcats)
       ("r-ggplot2" ,r-ggplot2)
       ("r-haven" ,r-haven)
       ("r-hms" ,r-hms)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-modelr" ,r-modelr)
       ("r-pillar" ,r-pillar)
       ("r-purrr" ,r-purrr)
       ("r-readr" ,r-readr)
       ("r-readxl" ,r-readxl)
       ("r-reprex" ,r-reprex)
       ("r-rlang" ,r-rlang)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-rvest" ,r-rvest)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)
       ("r-xml2" ,r-xml2)))
    (home-page "https://tidyverse.tidyverse.org")
    (synopsis "Install and load packages from the \"Tidyverse\"")
    (description
     "The @code{tidyverse} is a set of packages that work in harmony because
they share common data representations and API design.  This package is
designed to make it easy to install and load multiple tidyverse packages in a
single step.")
    (license license:gpl3)))

(define-public r-rvest
  (package
    (name "r-rvest")
    (version "0.3.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rvest" version))
       (sha256
        (base32 "0r0a5jic09xw5pk0x42pr99r3zab5m9s4x85ymx1sl769jz42zqf"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-httr" ,r-httr)
       ("r-magrittr" ,r-magrittr)
       ("r-selectr" ,r-selectr)
       ("r-xml2" ,r-xml2)))
    (home-page "https://github.com/hadley/rvest")
    (synopsis "Simple web scraping for R")
    (description
     "@code{r-rvest} helps you scrape information from web pages.  It is
designed to work with @code{magrittr} to make it easy to express common web
scraping tasks, inspired by libraries like @code{BeautifulSoup}.")
    (license license:gpl3)))

(define-public r-selectr
  (package
    (name "r-selectr")
    (version "0.4-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "selectr" version))
       (sha256
        (base32 "09y1n3iy297g49xlpl7xrjpwgnm57pskx5991lyfcpizbz8ax22m"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-stringr" ,r-stringr)
       ("r-r6" ,r-r6)))
    (home-page "https://sjp.co.nz/projects/selectr/")
    (synopsis "Translate CSS selectors to XPath expressions")
    (description
     "@code{r-selectr} translates a CSS3 selector into an equivalent XPath
expression.  This allows you to use CSS selectors when working with the XML
package as it can only evaluate XPath expressions.  Also provided are
convenience functions useful for using CSS selectors on XML nodes.  This
package is a port of the Python package @code{cssselect}.")
    (license license:bsd-3)))

(define-public r-reprex
  (package
    (name "r-reprex")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "reprex" version))
       (sha256
        (base32
         "0v7vxzs8alwz8y1cjicpimp5yimf1g9gb8x5wy3zhvrz6kk2lg10"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-callr" ,r-callr)
       ("r-clipr" ,r-clipr)
       ("r-fs" ,r-fs)
       ("r-rlang" ,r-rlang)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-whisker" ,r-whisker)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/tidyverse/reprex")
    (synopsis "Prepare reproducible R code examples for sharing")
    (description
     "This package provides a convenience wrapper that uses the
@code{rmarkdown} package to render small snippets of code to target formats
that include both code and output.  The goal is to encourage the sharing of
small, reproducible, and runnable examples on code-oriented websites or email.
@code{reprex} also extracts clean, runnable R code from various common formats,
such as copy/paste from an R session.")
    (license license:expat)))

(define-public r-callr
  (package
    (name "r-callr")
    (version "3.4.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "callr" version))
       (sha256
        (base32
         "0bdlp0labwyfl36jqslj2g7zmw7zwr58v9gam435kiblhjimb8fc"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-r6" ,r-r6)
       ("r-processx" ,r-processx)))
    (home-page "https://github.com/r-lib/callr#readme")
    (synopsis "Call R from R")
    (description
     "It is sometimes useful to perform a computation in a separate R process,
without affecting the current R process at all.  This package does exactly
that.")
    (license license:expat)))

(define-public r-readxl
  (package
    (name "r-readxl")
    (version "1.3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "readxl" version))
       (sha256
        (base32
         "15mambxr8c7k2ikdfsl1w3vxvm54dsnk0cl1qvks6iig7rql3d14"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cellranger" ,r-cellranger)
       ("r-progress" ,r-progress)
       ("r-rcpp" ,r-rcpp)
       ("r-tibble" ,r-tibble)))
    (home-page "https://readxl.tidyverse.org")
    (synopsis "Read Excel files")
    (description
     "This package lets you import Excel files into R.  It supports
@file{.xls} via the embedded @code{libxls} C library and @file{.xlsx} via
the embedded @code{RapidXML} C++ library.")
    ;; XXX: This package bundles a copy of 'libxsl' which is BSD-2 and
    ;; 'rapidxml' which is Boost.
    (license (list license:gpl3 license:bsd-2 license:boost1.0))))

(define-public r-modelr
  (package
    (name "r-modelr")
    (version "0.1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "modelr" version))
       (sha256
        (base32
         "1x2m34m4qirb401krmgc5wg3g7ndbcglfab2l0655rmky3fz7rfp"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-broom" ,r-broom)
       ("r-dplyr" ,r-dplyr)
       ("r-magrittr" ,r-magrittr)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)
       ("r-tidyselect" ,r-tidyselect)))
    (home-page "https://github.com/tidyverse/modelr")
    (synopsis "Helper functions for modelling in pipelines")
    (description
     "Functions for modelling that help you seamlessly integrate modelling
into a pipeline of data manipulation and visualisation.")
    (license license:gpl3)))

(define-public r-httpuv
  (package
    (name "r-httpuv")
    (version "1.5.2")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "httpuv" version))
              (sha256
               (base32
                "13ax0hs2lc39ilznh1zarwqdzahcbhb8adilrfik3xg0fkljpcwk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-later" ,r-later)
       ("r-promises" ,r-promises)
       ("r-r6" ,r-r6)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/rstudio/httpuv")
    (synopsis "HTTP and WebSocket server library for R")
    (description
     "The httpuv package provides low-level socket and protocol support for
handling HTTP and WebSocket requests directly from within R.  It is primarily
intended as a building block for other packages, rather than making it
particularly easy to create complete web applications using httpuv alone.")
    ;; This package includes third-party code that was originally released
    ;; under various non-copyleft licenses.  Full licensing information can be
    ;; obtained here: https://github.com/rstudio/httpuv/blob/master/LICENSE
    (license license:gpl3+)))

(define-public r-jsonlite
  (package
    (name "r-jsonlite")
    (version "1.6.1")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "jsonlite" version))
              (sha256
               (base32
                "0xrki07wc17bkmhz0h7jay784j1sls2i9bf1mfpj6yl59791v4kl"))))
    (build-system r-build-system)
    (home-page "https://arxiv.org/abs/1403.2805")
    (synopsis "Robust, high performance JSON parser and generator for R")
    (description
     "The jsonlite package provides a fast JSON parser and generator optimized
for statistical data and the web.  It offers flexible, robust, high
performance tools for working with JSON in R and is particularly powerful for
building pipelines and interacting with a web API.  In addition to converting
JSON data from/to R objects, jsonlite contains functions to stream, validate,
and prettify JSON data.  The unit tests included with the package verify that
all edge cases are encoded and decoded consistently for use with dynamic data
in systems and applications.")
    (license license:expat)))

(define-public r-servr
  (package
    (name "r-servr")
    (version "0.16")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "servr" version))
              (sha256
               (base32
                "106skz04iq4dkblr17idxsxfcfqic6rcaz8mahydkwjjppnhp5fc"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-httpuv" ,r-httpuv)
       ("r-jsonlite" ,r-jsonlite)
       ("r-mime" ,r-mime)
       ("r-xfun" ,r-xfun)))
    (home-page "https://github.com/yihui/servr")
    (synopsis "Simple HTTP server to serve static files or dynamic documents")
    (description
     "Servr provides an HTTP server in R to serve static files, or dynamic
documents that can be converted to HTML files (e.g., R Markdown) under a given
directory.")
    (license license:expat)))

(define-public r-htmltools
  (package
    (name "r-htmltools")
    (version "0.4.0")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "htmltools" version))
              (sha256
               (base32
                "06l17d8jkf438yk2mchpsp4j90bynnapz3nabh5vkcc324p5a62v"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)))
    (home-page "https://cran.r-project.org/web/packages/htmltools")
    (synopsis "R tools for HTML")
    (description
     "This package provides tools for HTML generation and output in R.")
    (license license:expat)))

(define-public r-htmlwidgets
  (package
    (name "r-htmlwidgets")
    (version "1.5.1")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "htmlwidgets" version))
              (sha256
               (base32
                "10fp306l1nybkah6jrlrqwwdb6zvklbddp8i3w9v9naj8la5jbnl"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-yaml" ,r-yaml)))
    (home-page "https://github.com/ramnathv/htmlwidgets")
    (synopsis "HTML Widgets for R")
    (description
     "HTML widgets is a framework for creating HTML widgets that render in
various contexts including the R console, R Markdown documents, and Shiny web
applications.")
    (license license:expat)))

(define-public r-htmltable
  (package
    (name "r-htmltable")
    (version "1.13.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "htmlTable" version))
       (sha256
        (base32
         "0g9r156k9yl1f092hfw3b9wjx11akf0shbi3x0d0mvpnflvc8nfl"))))
    (properties `((upstream-name . "htmlTable")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-checkmate" ,r-checkmate)
       ("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-knitr" ,r-knitr)
       ("r-magrittr" ,r-magrittr)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-stringr" ,r-stringr)))
    (home-page "http://gforge.se/packages/")
    (synopsis "Advanced tables for Markdown/HTML")
    (description
     "This package provides functions to build tables with advanced layout
elements such as row spanners, column spanners, table spanners, zebra
striping, and more.  While allowing advanced layout, the underlying
CSS-structure is simple in order to maximize compatibility with word
processors such as LibreOffice.  The package also contains a few text
formatting functions that help outputting text compatible with HTML or
LaTeX.")
    (license license:gpl3+)))

(define-public r-curl
  (package
    (name "r-curl")
    (version "4.3")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "curl" version))
              (sha256
               (base32
                "1nrf6md41b37j424y6rvifdj9zb3j14f60fj7q71k9jhpf2x81kl"))))
    (build-system r-build-system)
    (arguments
     `(#:phases
       (modify-phases %standard-phases
         ;; The environment variable CURL_CA_BUNDLE is only respected when
         ;; running Windows, so we disable the platform checks.
         ;; This can be removed once the libcurl has been patched.
         (add-after 'unpack 'allow-CURL_CA_BUNDLE
           (lambda _
             (substitute* "R/onload.R"
               (("if \\(!grepl\\(\"mingw\".*")
                "if (FALSE)\n"))
             (substitute* "src/handle.c"
               (("/\\* Only set" m)
                (string-append "\
const char *_ca_bundle = getenv(\"CURL_CA_BUNDLE\");
if(_ca_bundle != NULL) { curl_easy_setopt(handle, CURLOPT_CAINFO, _ca_bundle); }
" m)))
             #t)))))
    (inputs
     `(("libcurl" ,curl)
       ("zlib" ,zlib)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/jeroenooms/curl")
    (synopsis "HTTP client for R")
    (description
     "The @code{curl()} and @code{curl_download()} functions provide highly
configurable drop-in replacements for base @code{url()} and
@code{download.file()} with better performance, support for encryption, gzip
compression, authentication, and other @code{libcurl} goodies.  The core of
the package implements a framework for performing fully customized requests
where data can be processed either in memory, on disk, or streaming via the
callback or connection interfaces.")
    (license license:expat)))

(define-public r-hwriter
  (package
    (name "r-hwriter")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hwriter" version))
       (sha256
        (base32
         "0arjsz854rfkfqhgvpqbm9lfni97dcjs66isdsfvwfd2wz932dbb"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/hwriter")
    (synopsis "Output R objects in HTML format")
    (description
     "This package provides easy-to-use and versatile functions to output R
objects in HTML format.")
    (license license:lgpl2.1+)))

(define-public r-rjson
  (package
    (name "r-rjson")
    (version "0.2.20")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rjson" version))
       (sha256
        (base32
         "0v1zvdd3svnavklh7y5xbwrrkbvx6053r4c5hgnk7hz7bqg7qa1s"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rjson")
    (synopsis "JSON library for R")
    (description
     "This package provides functions to convert R objects into JSON objects
and vice-versa.")
    (license license:gpl2+)))

(define-public r-fastmap
  (package
    (name "r-fastmap")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fastmap" version))
       (sha256
        (base32
         "1v7sp56xiha0bh78g3w92k52p9vkp7ryzpw0z66nyddxzrfv0y27"))))
    (properties `((upstream-name . "fastmap")))
    (build-system r-build-system)
    (home-page "https://r-lib.github.io/fastmap/")
    (synopsis "Fast implementation of a key-value store")
    (description
     "This package provides a fast implementation of a key-value store.
Environments are commonly used as key-value stores, but every time a new key
is used, it is added to R's global symbol table, causing a small amount of
memory leakage.  This can be problematic in cases where many different keys
are used.  Fastmap avoids this memory leak issue by implementing the map using
data structures in C++.")
    (license license:expat)))

(define-public r-shiny
  (package
    (name "r-shiny")
    (version "1.4.0.2")
    (source
     (origin
       (method git-fetch)
       (uri (git-reference
             (url "https://github.com/rstudio/shiny.git")
             (commit (string-append "v" version))))
       (file-name (git-file-name name version))
       (sha256
        (base32
         "005wgcxq7f2q9g6wvfk29n2nms262w0abpz93sfvx79yv6qxppzs"))))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build r-build-system)
                  (guix build minify-build-system)
                  (guix build utils)
                  (ice-9 match))
       #:imported-modules (,@%r-build-system-modules
                           (guix build minify-build-system))
       #:phases
       (modify-phases (@ (guix build r-build-system) %standard-phases)
         (add-after 'unpack 'replace-bundled-minified-JavaScript
           (lambda* (#:key inputs #:allow-other-keys)
             (let ((replace-file (lambda (old new)
                                   (format #t "replacing ~a with ~a\n" old new)
                                   (delete-file old)
                                   (symlink new old))))
               ;; NOTE: Files in ./inst/www/shared/datepicker/js/locales/
               ;; contain just data.  They are not minified code, so we don't
               ;; replace them.
               (with-directory-excursion "inst/www/shared"
                 (replace-file "bootstrap/shim/respond.min.js"
                               (string-append (assoc-ref inputs "js-respond")
                                              "/share/javascript/respond.min.js"))
                 (replace-file "bootstrap/shim/html5shiv.min.js"
                               (string-append (assoc-ref inputs "js-html5shiv")
                                              "/share/javascript/html5shiv.min.js"))
                 (replace-file "json2-min.js"
                               (string-append (assoc-ref inputs "js-json2")
                                              "/share/javascript/json2-min.js"))
                 (replace-file "strftime/strftime-min.js"
                               (string-append (assoc-ref inputs "js-strftime")
                                              "/share/javascript/strftime.min.js"))
                 (replace-file "highlight/highlight.pack.js"
                               (string-append (assoc-ref inputs "js-highlight")
                                              "/share/javascript/highlight.min.js"))
                 (replace-file "datatables/js/jquery.dataTables.min.js"
                               (string-append (assoc-ref inputs "js-datatables")
                                              "/share/javascript/jquery.dataTables.min.js"))
                 (replace-file "selectize/js/selectize.min.js"
                               (string-append (assoc-ref inputs "js-selectize")
                                              "/share/javascript/selectize.min.js"))
                 (replace-file "selectize/js/es5-shim.min.js"
                               (string-append (assoc-ref inputs "js-es5-shim")
                                              "/share/javascript/es5-shim.min.js"))
                 (for-each (match-lambda
                             ((source . target)
                              (delete-file target)
                              (minify source #:target target)))
                           '(("jqueryui/jquery-ui.js" .
                              "jqueryui/jquery-ui.min.js")
                             ("datepicker/js/bootstrap-datepicker.js" .
                              "datepicker/js/bootstrap-datepicker.min.js")
                             ("ionrangeslider/js/ion.rangeSlider.js" .
                              "ionrangeslider/js/ion.rangeSlider.min.js")
                             ("bootstrap/js/bootstrap.js" .
                              "bootstrap/js/bootstrap.min.js")
                             ("shiny.js" .
                              "shiny.min.js")
                             ("jquery.js" .
                              "jquery.min.js")
                             ("legacy/jquery.js" .
                              "legacy/jquery.min.js")
                             ("showdown/src/showdown.js" .
                              "showdown/compressed/showdown.js")))))
             #t)))))
    (propagated-inputs
     `(("r-crayon" ,r-crayon)
       ("r-digest" ,r-digest)
       ("r-fastmap" ,r-fastmap)
       ("r-htmltools" ,r-htmltools)
       ("r-httpuv" ,r-httpuv)
       ("r-jsonlite" ,r-jsonlite)
       ("r-later" ,r-later)
       ("r-mime" ,r-mime)
       ("r-promises" ,r-promises)
       ("r-r6" ,r-r6)
       ("r-rlang" ,r-rlang)
       ("r-sourcetools" ,r-sourcetools)
       ("r-withr" ,r-withr)
       ("r-xtable" ,r-xtable)))
    (inputs
     `(("js-datatables" ,js-datatables)
       ("js-html5shiv" ,js-html5shiv)
       ("js-json2" ,js-json2)
       ("js-respond" ,js-respond)
       ("js-selectize" ,js-selectize)
       ("js-strftime" ,js-strftime)
       ("js-highlight" ,js-highlight)
       ("js-es5-shim" ,js-es5-shim)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("gfortran" ,gfortran)))
    (home-page "http://shiny.rstudio.com")
    (synopsis "Easy interactive web applications with R")
    (description
     "Makes it incredibly easy to build interactive web applications
with R.  Automatic \"reactive\" binding between inputs and outputs and
extensive prebuilt widgets make it possible to build beautiful,
responsive, and powerful applications with minimal effort.")
    (license license:artistic2.0)))

;; This package includes minified JavaScript files.  When upgrading please
;; check that there are no new minified JavaScript files.
(define-public r-shinytree
  (package
    (name "r-shinytree")
    (version "0.2.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinyTree" version))
       (sha256
        (base32
         "0jfx2capckv7hf2yx3fn8i4rcmhi222ah91jnmhg497x8wgz31s3"))
       (modules '((guix build utils)))
       (snippet
        '(begin
           ;; Delete minified JavaScript
           (for-each delete-file
                     '("inst/www/jsTree-3.3.7/libs/require.js"
                       "inst/www/jsTree-3.3.7/libs/jquery.js"
                       "inst/www/jsTree-3.3.7/jstree.min.js"))
           #t))))
    (properties `((upstream-name . "shinyTree")))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'replace-minified-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst/www/jsTree-3.3.7/"
               (symlink (string-append (assoc-ref inputs "js-requirejs")
                                       "/share/javascript/require.min.js")
                        "libs/require.js")
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "js-jquery")
                         "libs/jquery.js")
                        ("jstree.js"
                         "jstree.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (propagated-inputs
     `(("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-promises" ,r-promises)
       ("r-shiny" ,r-shiny)
       ("r-stringr" ,r-stringr)))
    (inputs
     `(("js-requirejs" ,js-requirejs)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("js-jquery"
        ,(origin
           (method url-fetch)
           (uri "https://code.jquery.com/jquery-3.3.1.js")
           (sha256
            (base32
             "1b8zxrp6xwzpw25apn8j4qws0f6sr7qr7h2va5h1mjyfqvn29anq"))))))
    (home-page "https://cran.r-project.org/web/packages/shinyTree/")
    (synopsis "jsTree bindings for Shiny")
    (description
     "This package exposes R bindings to jsTree, a JavaScript library that
supports interactive trees, to enable rich, editable trees in Shiny.")
    (license license:expat)))

(define-public r-shinydashboard
  (package
    (name "r-shinydashboard")
    (version "0.7.1")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "shinydashboard" version))
              (sha256
               (base32
                "0khac8b27q3swdw07kl609hm0fjfjsjv591b388q99mqqr2rk92i"))))
    (build-system r-build-system)
    ;; The directory inst/AdminLTE/ contains a minified JavaScript file.
    ;; Regenerate it from the included sources.
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'generate-minified-javascript
           (lambda _
             (with-directory-excursion "inst/AdminLTE"
               (delete-file "app.min.js")
               (let ((minified (open-pipe* OPEN_READ "uglify-js" "app.js")))
                 (call-with-output-file "app.min.js"
                   (lambda (port)
                     (dump-port minified port))))))))))
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-promises" ,r-promises)
       ("r-shiny" ,r-shiny)))
    (native-inputs
     `(("uglify-js" ,uglify-js)))
    (home-page "https://rstudio.github.io/shinydashboard/")
    (synopsis "Create dashboards with shiny")
    (description "This package provides an extension to the Shiny web
application framework for R, making it easy to create attractive dashboards.")
    ;; This package includes software that was released under the Expat
    ;; license, but the whole package is released under GPL version 2 or
    ;; later.
    (license license:gpl2+)))

(define-public r-shinyfiles
  (package
    (name "r-shinyfiles")
    (version "0.7.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinyFiles" version))
       (sha256
        (base32 "1143m941hma9hc77c3xcw26c0ygfhn9ii2sbp9wrydxv4gc7mr8a"))))
    (properties `((upstream-name . "shinyFiles")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fs" ,r-fs)
       ("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-shiny" ,r-shiny)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/thomasp85/shinyFiles")
    (synopsis "Server-side file system viewer for Shiny")
    (description
     "This package provides functionality for client-side navigation of the
server side file system in shiny apps.  In case the app is running locally
this gives the user direct access to the file system without the need to
\"download\" files to a temporary location.  Both file and folder selection as
well as file saving is available.")
    (license license:gpl2+)))

(define-public r-shinythemes
  (package
    (name "r-shinythemes")
    (version "1.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinythemes" version))
       (sha256
        (base32
         "12miz44n2zxfswnia7p8dirxj3miw0aqn4pkx2111ikz67ax84rf"))))
    (properties `((upstream-name . "shinythemes")))
    (build-system r-build-system)
    (propagated-inputs `(("r-shiny" ,r-shiny)))
    (home-page "https://rstudio.github.io/shinythemes/")
    (synopsis "Themes for Shiny")
    (description
     "This package provides themes for use with Shiny.  It includes several
Bootstrap themes, which are packaged for use with Shiny applications.")
    ;; The package is released under version 3 of the GPL, but it includes
    ;; source files that are covered by the Expat license.  It also includes
    ;; fonts under SIL or the ASL.
    (license (list license:gpl3 license:expat
                   license:silofl1.1 license:asl2.0))))

;; The package sources include minified variants of d3.js and non-minified
;; source code of d3-jetpack.
(define-public r-d3r
  (package
    (name "r-d3r")
    (version "0.8.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "d3r" version))
       (sha256
        (base32
         "0xl3im76lp7pd5lhp8jfyqdm4j4zvjrx5a5fl81xv2cf7x3n4f2a"))))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst/www/d3/"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "d3.v3.js")
                         "v3/dist/d3.min.js")
                        (,(assoc-ref inputs "d3.v4.js")
                         "v4/dist/d3.min.js")
                        (,(assoc-ref inputs "d3.v5.js")
                         "v5/dist/d3.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (delete-file target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-htmltools" ,r-htmltools)
       ("r-tidyr" ,r-tidyr)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("d3.v3.js"
        ,(origin
           (method url-fetch)
           (uri "https://d3js.org/d3.v3.js")
           (sha256
            (base32
             "1arr7sr08vy7wh0nvip2mi7dpyjw4576vf3bm45rp4g5lc1k1x41"))))
       ("d3.v4.js"
        ,(origin
           (method url-fetch)
           (uri "https://d3js.org/d3.v4.js")
           (sha256
            (base32
             "0y7byf6kcinfz9ac59jxc4v6kppdazmnyqfav0dm4h550fzfqqlg"))))
       ("d3.v5.js"
        ,(origin
           (method url-fetch)
           (uri "https://d3js.org/d3.v5.js")
           (sha256
            (base32
             "0kxvx5pfagxn6nhavdwsdnzyd26g0z5dsfi1pi5dvcmb0c8ipcdn"))))))
    (home-page "https://github.com/timelyportfolio/d3r")
    (synopsis "d3.js utilities for R")
    (description
     "This package provides a suite of functions to help ease the use of the
d3.js visualization library in R.  These helpers include
@code{htmltools::htmlDependency} functions, hierarchy builders, and conversion
tools for @code{partykit}, @code{igraph}, @code{table}, and @code{data.frame}
R objects into the JSON format that the d3.js library expects.")
    (license license:bsd-3)))

;; We use the latest commit here because the last release was in 2016 while
;; the latest commit was in 2018.
(define-public r-sankeyd3
  (let ((commit "fd50a74e29056e0d67d75b4d04de47afb2f932bc")
        (revision "1"))
    (package
      (name "r-sankeyd3")
      (version (git-version "0.3.2" revision commit))
      (source
       (origin
         (method git-fetch)
         (uri (git-reference
               (url "https://github.com/fbreitwieser/sankeyD3.git")
               (commit commit)))
         (file-name (git-file-name name version))
         (sha256
          (base32
           "0jrcnfax321pszbpjdifnkbrgbjr43bjzvlzv1p5a8wskksqwiyx"))))
      (build-system r-build-system)
      (propagated-inputs
       `(("r-d3r" ,r-d3r)
         ("r-htmlwidgets" ,r-htmlwidgets)
         ("r-shiny" ,r-shiny)
         ("r-magrittr" ,r-magrittr)))
      (home-page "https://github.com/fbreitwieser/sankeyD3")
      (synopsis "Sankey network graphs from R")
      (description
       "This package provides an R library to generate Sankey network graphs
in R and Shiny via the D3 visualization library.")
      ;; The R code is licensed under GPLv3+.  It includes the non-minified
      ;; JavaScript source code of d3-sankey, which is released under the
      ;; 3-clause BSD license.
      (license (list license:gpl3+ license:bsd-3)))))

(define-public r-crosstalk
  (package
    (name "r-crosstalk")
    (version "1.1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "crosstalk" version))
       (sha256
        (base32
         "03ihj7cimkklrbad9zic78xsrfcisygmgy859hqnx0hiph80p9rn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-lazyeval" ,r-lazyeval)
       ("r-r6" ,r-r6)))
    (home-page "https://rstudio.github.io/crosstalk/")
    (synopsis "Inter-widget interactivity for HTML widgets")
    (description
     "This package provides building blocks for allowing HTML widgets to
communicate with each other, with Shiny or without (i.e.  static @code{.html}
files).  It currently supports linked brushing and filtering.")
    (license license:expat)))

(define-public r-rook
  (package
    (name "r-rook")
    (version "1.1-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rook" version))
       (sha256
        (base32
         "00s9a0kr9rwxvlq433daxjk4ji8m0w60hjdprf502msw9kxfrx00"))))
    (properties `((upstream-name . "Rook")))
    (build-system r-build-system)
    (propagated-inputs `(("r-brew" ,r-brew)))
    (home-page "https://cran.r-project.org/web/packages/Rook")
    (synopsis "Web server interface for R")
    (description
     "This package contains the Rook specification and convenience software
for building and running Rook applications.  A Rook application is an R
reference class object that implements a @code{call} method or an R closure
that takes exactly one argument, an environment, and returns a list with three
named elements: the @code{status}, the @code{headers}, and the @code{body}.")
    (license license:gpl2)))

(define-public r-miniui
  (package
    (name "r-miniui")
    (version "0.1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "miniUI" version))
       (sha256
        (base32
         "1h5h2sc57h95d6bsgs95l26911g38hvjc1v50bc31xl9689l2as5"))))
    (properties `((upstream-name . "miniUI")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-shiny" ,r-shiny)))
    (home-page "https://cran.r-project.org/web/packages/miniUI/")
    (synopsis "Shiny UI widgets for small screens")
    (description
     "This package provides UI widget and layout functions for writing Shiny apps that
work well on small screens.")
    (license license:gpl3)))

(define-public r-feather
  (package
    (name "r-feather")
    (version "0.3.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "feather" version))
       (sha256
        (base32
         "1gxd0h2m56sjjlzn4dry6s13nddxc4l5i11gsvavaf2dwbahdzsh"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-hms" ,r-hms)
       ("r-rcpp" ,r-rcpp)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/wesm/feather")
    (synopsis "R Bindings to the Feather API")
    (description "Read and write feather files, a lightweight binary columnar
data store designed for maximum speed.")
    (license license:asl2.0)))

(define-public r-maps
  (package
    (name "r-maps")
    (version "3.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "maps" version))
       (sha256
        (base32
         "05i2ppl5z4p8rawgqmy3z4ia05fcblpq1vvrmrkgkkpdlhczx6hr"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/maps")
    (synopsis "Draw geographical maps")
    (description "This package provides an R module for display of maps.
Projection code and larger maps are in separate packages (@code{mapproj} and
@code{mapdata}).")
    (license license:gpl2)))

(define-public r-mapproj
  (package
    (name "r-mapproj")
    (version "1.2.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mapproj" version))
       (sha256
        (base32
         "0nscsfq8md6ri9258xz57c3dj81wdl6kdwf4a9qcrwwbn20i427h"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-maps" ,r-maps)))
    (home-page "https://cran.r-project.org/web/packages/mapproj")
    (synopsis "Map projection in R")
    (description "This package converts latitude/longitude into projected
coordinates.")
    (license (list license:gpl2          ; The R interface
                   (license:non-copyleft ; The C code
                    "https://www.gnu.org/licenses/license-list.en.html#lucent102"
                    "Lucent Public License Version 1.02")))))

(define-public r-rgooglemaps
  (package
    (name "r-rgooglemaps")
    (version "1.4.5.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RgoogleMaps" version))
       (sha256
        (base32
         "02v8k0bw70q4qwx4lcdy8p25q7n3ql2ll46lfpqllxa1p26svmfi"))))
    (properties `((upstream-name . "RgoogleMaps")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-png" ,r-png)
       ("r-sp" ,r-sp)))
    (home-page "https://cran.r-project.org/web/packages/RgoogleMaps")
    (synopsis "Use Google Maps in R")
    (description "This package serves two purposes:
@enumerate
@item Provide a comfortable R interface to query the Google server for static
  maps, and
@item Use the map as a background image to overlay plots within R.  This
  requires proper coordinate scaling.
@end enumerate\n")
    (license license:gpl2+)))

(define-public r-geosphere
  (package
    (name "r-geosphere")
    (version "1.5-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "geosphere" version))
       (sha256
        (base32
         "15xlgsmn0vwky1l13n6acdz6jn2b2na3gf6x367y3qh1f5w4zkan"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-sp" ,r-sp)))
    (home-page "https://cran.r-project.org/web/packages/geosphere")
    (synopsis "Spherical trigonometry")
    (description "This package computes spherical trigonometry for geographic
applications.  That is, compute distances and related measures for angular
(longitude/latitude) locations.")
    (license license:gpl3+)))

(define-public r-jpeg
  (package
    (name "r-jpeg")
    (version "0.1-8.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "jpeg" version))
       (sha256
        (base32
         "1a8mi70x79a691r40yiw684jkg1mr9n8agkxlcksxcnrdybs9c0x"))))
    (build-system r-build-system)
    (inputs `(("libjpeg" ,libjpeg)))
    (home-page "https://www.rforge.net/jpeg/")
    (synopsis "Read and write JPEG images with R")
    (description "This package provides a way to read, write and display
bitmap images stored in the JPEG format with R.  It can read and write both
files and in-memory raw vectors.")
    (license license:gpl2+)))

(define-public r-ggmap
  (package
    (name "r-ggmap")
    (version "3.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggmap" version))
       (sha256
        (base32
         "13dmzl6z62pzjiffilarkji46vy0sacxa8a7mhrhc3biq3ylzhln"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bitops" ,r-bitops)
       ("r-digest" ,r-digest)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-glue" ,r-glue)
       ("r-httr" ,r-httr)
       ("r-jpeg" ,r-jpeg)
       ("r-magrittr" ,r-magrittr)
       ("r-plyr" ,r-plyr)
       ("r-png" ,r-png)
       ("r-purrr" ,r-purrr)
       ("r-rgooglemaps" ,r-rgooglemaps)
       ("r-rjson" ,r-rjson)
       ("r-scales" ,r-scales)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/dkahle/ggmap")
    (synopsis "Spatial visualization with ggplot2")
    (description "This package provides a collection of functions to visualize
spatial data and models on top of static maps from various online sources (e.g
Google Maps and Stamen Maps).  It includes tools common to those tasks,
including functions for geolocation and routing.")
    (license license:gpl2)))

(define-public r-haven
  (package
    (name "r-haven")
    (version "2.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "haven" version))
       (sha256
        (base32
         "0g9d6mxqmrw2zdms78jpx2sx73pczlyy771v1h5hmxqz9sqyk7hr"))))
    (build-system r-build-system)
    (inputs
     `(("zlib" ,zlib)))
    (propagated-inputs
     `(("r-forcats" ,r-forcats)
       ("r-hms" ,r-hms)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)
       ("r-readr" ,r-readr)
       ("r-tibble" ,r-tibble)
       ("r-tidyselect" ,r-tidyselect)))
    (home-page "https://haven.tidyverse.org")
    (synopsis "Import and Export 'SPSS', 'Stata' and 'SAS' Files")
    (description
     "This package lets you mport foreign statistical formats into R via the
embedded @url{https://github.com/WizardMac/ReadStat,ReadStat} C library.")
    (license license:expat)))

(define-public r-amap
  (package
    (name "r-amap")
    (version "0.8-18")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "amap" version))
              (sha256
               (base32
                "0zpcb73w413na23f6giml9311jh0j0y766w2fh9i40d2h7bbvyvs"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "http://mulcyber.toulouse.inra.fr/projects/amap/")
    (synopsis "Another multidimensional analysis package")
    (description "This package provides tools for clustering and principal
component analysis (with robust methods, and parallelized functions).")
    (license license:gpl2+)))

(define-public r-ape
  (package
    (name "r-ape")
    (version "5.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ape" version))
       (sha256
        (base32
         "08wbk1kxhs32bmmvqlqanbdg1w235amd35k8m00fngsj9h9xzc08"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)
       ("r-nlme" ,r-nlme)
       ("r-rcpp" ,r-rcpp)))
    (home-page "http://ape-package.ird.fr/")
    (synopsis "Analyses of phylogenetics and evolution")
    (description
     "This package provides functions for reading, writing, plotting, and
manipulating phylogenetic trees, analyses of comparative data in a
phylogenetic framework, ancestral character analyses, analyses of
diversification and macroevolution, computing distances from DNA sequences,
and several other tools.")
    (license license:gpl2+)))

(define-public r-abbyyr
  (package
    (name "r-abbyyr")
    (version "0.5.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abbyyR" version))
       (sha256
        (base32
         "1vldnd3dg89aj6a73nhirirqddbfdrnzhb5m3679i60sark8nk6r"))))
    (properties `((upstream-name . "abbyyR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-httr" ,r-httr)
       ("r-plyr" ,r-plyr)
       ("r-progress" ,r-progress)
       ("r-readr" ,r-readr)
       ("r-xml" ,r-xml)))
    (home-page "https://github.com/soodoku/abbyyR")
    (synopsis "Access to Abbyy Optical Character Recognition (OCR) API")
    (description
     "This package provides tools to get text from images of text using Abbyy
Cloud Optical Character Recognition (OCR) API.  With abbyyyR, one can easily
OCR images, barcodes, forms, documents with machine readable zones, e.g.
passports and get the results in a variety of formats including plain text and
XML.  To learn more about the Abbyy OCR API, see @url{http://ocrsdk.com/}.")
    (license license:expat)))

(define-public r-colorspace
  (package
    (name "r-colorspace")
    (version "1.4-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "colorspace" version))
       (sha256
        (base32 "0wyny3ah2d74hqv80s6imrarpna09gq3j9rjnz6zx2qg0lx72gb9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/colorspace")
    (synopsis "Color space manipulation")
    (description
     "This package carries out a mapping between assorted color spaces
including RGB, HSV, HLS, CIEXYZ, CIELUV, HCL (polar CIELUV), CIELAB and polar
CIELAB.  Qualitative, sequential, and diverging color palettes based on HCL
colors are provided.")
    (license license:bsd-3)))

(define-public r-glue
  (package
    (name "r-glue")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "glue" version))
       (sha256
        (base32
         "0alklqcf68kmccssp4j7a7fv553pyqyy6mkkfslav83inppm4d3g"))))
    (build-system r-build-system)
    (home-page "https://github.com/tidyverse/glue")
    (synopsis "Interpreted string literals")
    (description
     "This package provides an implementation of interpreted string literals,
inspired by Python's Literal String Interpolation (PEP-0498) and
Docstrings (PEP-0257) and Julia's Triple-Quoted String Literals.")
    (license license:expat)))

(define-public r-pastecs
  (package
   (name "r-pastecs")
   (version "1.3.21")
   (source (origin
            (method url-fetch)
            (uri (cran-uri "pastecs" version))
            (sha256
             (base32
              "0z4dic94ar646w7zc2ggi5hgvf2qnznsani94c5pyql8zspz47lc"))))
   (build-system r-build-system)
   (propagated-inputs
    `(("r-boot" ,r-boot)))
   (home-page "http://www.sciviews.org/pastecs")
   (synopsis "Analysis of space-time ecological series")
   (description
    "This package provides functions for regulation, decomposition and analysis
of space-time series.  The @code{pastecs} library is a PNEC-Art4 and IFREMER
initiative to bring PASSTEC 2000 functionalities to R.")
   (license license:gpl2+)))

(define-public r-plogr
  (package
    (name "r-plogr")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "plogr" version))
       (sha256
        (base32
         "0a8dhzlna79ggyhfr0nncgh15a9n6r0dsz664pz0ah323wpblqqf"))))
    (build-system r-build-system)
    (home-page "https://github.com/krlmlr/plogr")
    (synopsis "R bindings for the plog C++ logging library")
    (description
     "This package provides the header files for a stripped-down version of
the plog header-only C++ logging library, and a method to log to R's standard
error stream.")
    (license license:expat)))

(define-public r-pls
  (package
    (name "r-pls")
    (version "2.7-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pls" version))
       (sha256
        (base32 "121byimd6bg7jbrq5wz5fpi0vxq0vh8g724vkhnjzszbvcv1xsb7"))))
    (build-system r-build-system)
    (home-page "https://mevik.net/work/software/pls.html")
    (synopsis "Partial Least Squares and Principal Component Regression")
    (description
     "The pls package implements multivariate regression methods: Partial Least
Squares Regression (@dfn{PLSR}), Principal Component Regression (@dfn{PCR}), and
Canonical Powered Partial Least Squares (@dfn{CPPLS}).  It supports:

@itemize
@item several algorithms: the traditional orthogonal scores (@dfn{NIPALS}) PLS
algorithm, kernel PLS, wide kernel PLS, Simpls, and PCR through @code{svd}
@item multi-response models (or @dfn{PLS2})
@item flexible cross-validation
@item Jackknife variance estimates of regression coefficients
@item extensive and flexible plots: scores, loadings, predictions, coefficients,
(R)MSEP, R², and correlation loadings
@item formula interface, modelled after @code{lm()}, with methods for predict,
print, summary, plot, update, etc.
@item extraction functions for coefficients, scores, and loadings
@item MSEP, RMSEP, and R² estimates
@item multiplicative scatter correction (@dfn{MSC})
@end itemize\n")
    (license license:gpl2)))

(define-public r-ps
  (package
    (name "r-ps")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ps" version))
       (sha256
        (base32 "0127q6pw9iw8hhcfp231gmdh29nahh2n5jzc38avrzy7yrm4bwl9"))))
    (build-system r-build-system)
    (home-page "https://ps.r-lib.org")
    (synopsis "List, query, and manipulate system processes")
    (description
     "The ps package implements an API to list, query, and manipulate system
processes.  Most of its code is based on the @code{psutil} Python package.")
    (license license:bsd-3)))

(define-public r-pkgbuild
  (package
    (name "r-pkgbuild")
    (version "1.0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pkgbuild" version))
       (sha256
        (base32 "0xnlz6ivhkbmncg9hfw5p69lm4rjy3wn5lyxmygxyf4rrfnnqwxx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-callr" ,r-callr)
       ("r-cli" ,r-cli)
       ("r-crayon" ,r-crayon)
       ("r-desc" ,r-desc)
       ("r-prettyunits" ,r-prettyunits)
       ("r-r6" ,r-r6)
       ("r-rprojroot" ,r-rprojroot)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/r-pkgs/pkgbuild")
    (synopsis "Find tools needed to build R packages")
    (description
     "This package provides functions used to build R packages.  It locates
compilers needed to build R packages on various platforms and ensures the PATH
is configured appropriately so R can use them.")
    (license license:gpl3)))

(define-public r-pkgload
  (package
    (name "r-pkgload")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pkgload" version))
       (sha256
        (base32
         "0z7jvharafahi2gv5547mk1n499isjzw06kfwymmxc0gd575d1ii"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-desc" ,r-desc)
       ("r-pkgbuild" ,r-pkgbuild)
       ("r-rlang" ,r-rlang)
       ("r-rprojroot" ,r-rprojroot)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/r-lib/pkgload")
    (synopsis "Simulate package installation and attach")
    (description
     "This package simulates the process of installing a package and then
attaching it.  This is a key part of the @code{devtools} package as it allows
you to rapidly iterate while developing a package.")
    (license license:gpl3)))

(define-public r-rcpp
  (package
    (name "r-rcpp")
    (version "1.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rcpp" version))
       (sha256
        (base32 "1m80pdhzi2p82db5xkbwc2m3fzv6df59955yj03nlq40fj7zx4nr"))))
    (build-system r-build-system)
    (home-page "http://www.rcpp.org")
    (synopsis "Seamless R and C++ integration")
    (description
     "The Rcpp package provides R functions as well as C++ classes which offer
a seamless integration of R and C++.  Many R data types and objects can be
mapped back and forth to C++ equivalents which facilitates both writing of new
code as well as easier integration of third-party libraries.  Documentation
about Rcpp is provided by several vignettes included in this package, via the
@code{Rcpp Gallery} site at <http://gallery.rcpp.org>, the paper by Eddelbuettel
and Francois (2011, JSS), and the book by Eddelbuettel (2013, Springer); see
@code{citation(\"Rcpp\")} for details on these last two.")
    (license license:gpl2+)))

(define-public r-bindr
  (package
    (name "r-bindr")
    (version "0.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bindr" version))
       (sha256
        (base32
         "1l05fpk2yql3jka321c0bdgx6mqq9pvfrg2844lbjfpbgjkmqy3w"))))
    (build-system r-build-system)
    (home-page "https://github.com/krlmlr/bindr")
    (synopsis "Parametrized active bindings")
    (description
     "This package provides a simple interface for creating active bindings
where the bound function accepts additional arguments.")
    (license license:expat)))

(define-public r-bindrcpp
  (package
    (name "r-bindrcpp")
    (version "0.2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bindrcpp" version))
       (sha256
        (base32
         "0rz4ibjdjsxl99ff3ha79z7cnjmilx4rx58fk9kk7ld9xc4hf4s8"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bindr" ,r-bindr)
       ("r-plogr" ,r-plogr)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/krlmlr/bindrcpp")
    (synopsis "Rcpp interface to active bindings")
    (description
     "This package provides an easy way to fill an environment with active
bindings that call a C++ function.")
    (license license:expat)))

(define-public r-auc
  (package
    (name "r-auc")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AUC" version))
       (sha256
        (base32
         "0ripcib2qz0m7rgr1kiz68nx8f6p408l1ww7j78ljqik7p3g41g7"))))
    (properties `((upstream-name . "AUC")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/AUC")
    (synopsis "Compute the area under the curve of selected measures")
    (description
     "This package includes functions to compute the area under the curve of
selected measures: the area under the sensitivity curve (AUSEC), the area
under the specificity curve (AUSPC), the area under the accuracy
curve (AUACC), and the area under the receiver operating characteristic
curve (AUROC).  The curves can also be visualized.  Support for partial areas
is provided.")
    (license license:gpl2+)))

(define-public r-calibrate
  (package
    (name "r-calibrate")
    (version "1.7.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "calibrate" version))
       (sha256
        (base32 "1s423nr176l2sc66wp7hzgqkv7c2bq8d2bjrrvrrm5qa9y3zdx1k"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/calibrate")
    (synopsis "Calibration of scatterplot and biplot axes")
    (description
     "This is a package for drawing calibrated scales with tick marks
on (non-orthogonal) variable vectors in scatterplots and biplots.")
    (license license:gpl2)))

(define-public r-shape
  (package
    (name "r-shape")
    (version "1.4.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shape" version))
       (sha256
        (base32
         "0hadk3mapkhbh8xjkiz52vxdagmmgvm15xwpzb90ikw4giyipjzl"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/shape")
    (synopsis "Functions for plotting graphical shapes")
    (description
     "This package provides functions for plotting graphical shapes such as
ellipses, circles, cylinders, arrows, ...")
    (license license:gpl3+)))

(define-public r-globaloptions
  (package
    (name "r-globaloptions")
    (version "0.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GlobalOptions" version))
       (sha256
        (base32 "0x89hfz80avq4zcskxl71i4zi0mgniqqxfrvz050aa2189wfyja2"))))
    (properties `((upstream-name . "GlobalOptions")))
    (build-system r-build-system)
    (home-page "https://github.com/jokergoo/GlobalOptions")
    (synopsis "Generate functions to get or set global options")
    (description
     "This package provides more controls on the option values such as
validation and filtering on the values, making options invisible or private.")
    (license license:gpl2+)))

(define-public r-circlize
  (package
    (name "r-circlize")
    (version "0.4.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "circlize" version))
       (sha256
        (base32
         "0jvr9hmxyhg0zx101iiqkrg8wfaj86kp62xpv42n2j9fkn5r1mi2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colorspace" ,r-colorspace)
       ("r-globaloptions" ,r-globaloptions)
       ("r-shape" ,r-shape)))
    (home-page "https://github.com/jokergoo/circlize")
    (synopsis "Circular visualization")
    (description
     "Circular layout is an efficient way to visualise huge amounts of
information.  This package provides an implementation of circular layout
generation in R as well as an enhancement of available software.  Its
flexibility is based on the usage of low-level graphics functions such that
self-defined high-level graphics can be easily implemented by users for
specific purposes.  Together with the seamless connection between the powerful
computational and visual environment in R, it gives users more convenience and
freedom to design figures for better understanding complex patterns behind
multi-dimensional data.")
    (license license:gpl2+)))

(define-public r-powerlaw
  (package
    (name "r-powerlaw")
    (version "0.70.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "poweRlaw" version))
       (sha256
        (base32
         "1asr6ikr7hmj78jyg8r1gwvcjg14addkxdiz92nh06lv71a183r4"))))
    (properties `((upstream-name . "poweRlaw")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-vgam" ,r-vgam)))
    (home-page "https://github.com/csgillespie/poweRlaw")
    (synopsis "Tools for the analysis of heavy tailed distributions")
    (description
     "This package provides an implementation of maximum likelihood estimators
for a variety of heavy tailed distributions, including both the discrete and
continuous power law distributions.  Additionally, a goodness-of-fit based
approach is used to estimate the lower cut-off for the scaling region.")
    ;; Any of these GPL versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-compare
  (package
    (name "r-compare")
    (version "0.2-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "compare" version))
       (sha256
        (base32
         "0k9zms930b5dz9gy8414li21wy0zg9x9vp7301v5cvyfi0g7xzgw"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/compare")
    (synopsis "Comparing objects for differences")
    (description
     "This package provides functions to compare a model object to a
comparison object.  If the objects are not identical, the functions can be
instructed to explore various modifications of the objects (e.g., sorting
rows, dropping names) to see if the modified versions are identical.")
    (license license:gpl2+)))

(define-public r-dendextend
  (package
    (name "r-dendextend")
    (version "1.13.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dendextend" version))
       (sha256
        (base32
         "1pjbz6sb4pgh3d5pm53vmf3q8y6lq3hrgjd6547xxs3m63sb8mn4"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-magrittr" ,r-magrittr)
       ("r-viridis" ,r-viridis)))
    (home-page "https://cran.r-project.org/web/packages/dendextend")
    (synopsis "Extending 'dendrogram' functionality in R")
    (description
     "This package offers a set of functions for extending @code{dendrogram}
objects in R, letting you visualize and compare trees of hierarchical
clusterings.  You can adjust a tree's graphical parameters (the color, size,
type, etc of its branches, nodes and labels) and visually and statistically
compare different dendrograms to one another.")
    ;; Any of these versions
    (license (list license:gpl2 license:gpl3))))

(define-public r-getoptlong
  (package
    (name "r-getoptlong")
    (version "0.1.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GetoptLong" version))
       (sha256
        (base32
         "1l8xkvyl152bsyvxazsvx2sm1vkygn75x0lsg3sbg7xp6drdn3kc"))))
    (properties `((upstream-name . "GetoptLong")))
    (build-system r-build-system)
    (inputs
     `(("perl" ,perl)))
    (propagated-inputs
     `(("r-globaloptions" ,r-globaloptions)
       ("r-rjson" ,r-rjson)))
    (home-page "https://github.com/jokergoo/GetoptLong")
    (synopsis "Parsing command-line arguments and variable interpolation")
    (description
     "This is yet another command-line argument parser which wraps the
powerful Perl module @code{Getopt::Long} and with some adaptation for easier
use in R.  It also provides a simple way for variable interpolation in R.")
    (license license:gpl2+)))

(define-public r-fastmatch
  (package
    (name "r-fastmatch")
    (version "1.1-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fastmatch" version))
       (sha256
        (base32
         "0z80jxkygmzn11sq0c2iz357s9bpki548lg926g85gldhfj1md90"))))
    (build-system r-build-system)
    (home-page "https://www.rforge.net/fastmatch")
    (synopsis "Fast match function")
    (description
     "This package provides a fast @code{match} replacement for cases that
require repeated look-ups.  It is slightly faster that R's built-in
@code{match} function on first match against a table, but extremely fast on
any subsequent lookup as it keeps the hash table in memory.")
    (license license:gpl2)))

(define-public r-ff
  (package
    (name "r-ff")
    (version "2.2-14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ff" version))
       (sha256
        (base32
         "1w724q4jpzbvzpilb2ifviaxkjgk9lzwxz9gksnvicbmfa20fqqw"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-bit" ,r-bit)))
    (home-page "http://ff.r-forge.r-project.org/")
    (synopsis "Memory-efficient storage of large data on disk and access functions")
    (description
     "This package provides data structures that are stored on disk but
behave (almost) as if they were in RAM by transparently mapping only a section
in main memory.")
    ;; error Architecture not supported.
    (supported-systems (delete "aarch64-linux" %supported-systems))
    (license license:gpl2)))

(define-public r-ffbase
  (package
    (name "r-ffbase")
    (version "0.12.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ffbase" version))
       (sha256
        (base32
         "0mjk7dkq1ginqqfvngzny747ggf9a8fd7kblq96n5ys1jrwjyqhq"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bit" ,r-bit)
       ("r-fastmatch" ,r-fastmatch)
       ("r-ff" ,r-ff)))
    (home-page "http://github.com/edwindj/ffbase")
    (synopsis "Basic statistical functions for package 'ff'")
    (description
     "This package extends the out of memory vectors of @code{ff} with
statistical functions and other utilities to ease their usage.")
    (license license:gpl3)))

(define-public r-prettyunits
  (package
    (name "r-prettyunits")
    (version "1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "prettyunits" version))
       (sha256
        (base32
         "1ibmzgknw5896q2i6r59jz2izblxwgb29ivvjzx50pkd1jl9l6cs"))))
    (build-system r-build-system)
    (home-page "https://github.com/gaborcsardi/prettyunits")
    (synopsis "Pretty, human readable formatting of quantities")
    (description
     "This package provides tools for pretty, human readable formatting of
quantities.")
    (license license:expat)))

(define-public r-reshape
  (package
    (name "r-reshape")
    (version "0.8.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "reshape" version))
       (sha256
        (base32
         "0s6i0sqxg1vldxs6miv8mi0zydxbqzgpmzfiwkj8y7jix3yrfmad"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-plyr" ,r-plyr)
       ("r-rcpp" ,r-rcpp)))
    (home-page "http://had.co.nz/reshape")
    (synopsis "Flexibly reshape data")
    (description
     "Flexibly restructure and aggregate data using just two functions:
@code{melt} and @code{cast}.  This package provides them.")
    (license license:expat)))

(define-public r-progress
  (package
    (name "r-progress")
    (version "1.2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "progress" version))
       (sha256
        (base32
         "0dgzb362641aqm8xd88iqa8jmpdm43xs0aba0d5kk6fvapnxi95l"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-crayon" ,r-crayon)
       ("r-hms" ,r-hms)
       ("r-prettyunits" ,r-prettyunits)
       ("r-r6" ,r-r6)))
    (home-page "https://github.com/gaborcsardi/progress")
    (synopsis "Terminal progress bars")
    (description
     "This package provides configurable progress bars.  They may include
percentage, elapsed time, and/or the estimated completion time.  They work in
terminals, in Emacs ESS, RStudio, Windows Rgui, and the macOS R.app.  The
package also provides a C++ API, that works with or without Rcpp.")
    (license license:expat)))

(define-public r-ggally
  (package
    (name "r-ggally")
    (version "1.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GGally" version))
       (sha256
        (base32
         "082s321zspg5al6acigwrhg4fsrmkkk5caabg662qbcy8v6n34h6"))))
    (properties `((upstream-name . "GGally")))
    (build-system r-build-system)
    (inputs
     `(("libressl" ,libressl)))
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gtable" ,r-gtable)
       ("r-plyr" ,r-plyr)
       ("r-progress" ,r-progress)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-reshape" ,r-reshape)
       ("r-rlang" ,r-rlang)))
    (home-page "https://ggobi.github.io/ggally")
    (synopsis "Extension to ggplot2")
    (description
     "The R package ggplot2 is a plotting system based on the grammar of
graphics.  GGally extends ggplot2 by adding several functions to reduce the
complexity of combining geometric objects with transformed data.  Some of
these functions include a pairwise plot matrix, a two group pairwise plot
matrix, a parallel coordinates plot, a survival plot, and several functions to
plot networks.")
    (license license:gpl2+)))

(define-public r-proxy
  (package
    (name "r-proxy")
    (version "0.4-23")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "proxy" version))
       (sha256
        (base32
         "17b6qfllqrhzrxqgx7dccffgybnkcria5a68ap5ly3plg04ypm4x"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/proxy")
    (synopsis "Distance and similarity measures")
    (description
     "This package provides an extensible framework for the efficient
calculation of auto- and cross-proximities, along with implementations of the
most popular ones.")
    (license license:gpl2)))

(define-public r-sp
  (package
    (name "r-sp")
    (version "1.4-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sp" version))
       (sha256
        (base32 "0fbh865r4py89g6ln8bslig2vbxxwa642p5k5g02rskyhajg35lg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)))
    (home-page "https://cran.r-project.org/web/packages/sp")
    (synopsis "Classes and methods for spatial data")
    (description
     "This package provides classes and methods for spatial data; the classes
document where the spatial location information resides, for 2D or 3D data.
Utility functions are provided, e.g. for plotting data as maps, spatial
selection, as well as methods for retrieving coordinates, for subsetting,
print, summary, etc.")
    (license license:gpl2+)))

(define-public r-rmtstat
  (package
    (name "r-rmtstat")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RMTstat" version))
       (sha256
        (base32
         "1nn25q4kmh9kj975sxkrpa97vh5irqrlqhwsfinbck6h6ia4rsw1"))))
    (properties `((upstream-name . "RMTstat")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/RMTstat")
    (synopsis "Distributions, statistics and tests derived from random matrix theory")
    (description
     "This package provides functions for working with the Tracy-Widom laws
and other distributions related to the eigenvalues of large Wishart
matrices.")
    (license license:bsd-3)))

(define-public r-rmpi
  (package
    (name "r-rmpi")
    (version "0.6-9")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "Rmpi" version))
              (sha256
               (base32
                "1rhycla98hxgnnxlxxldr1x51djak7c2jjvlrv3jcsvgwp1ymqdj"))))
    (properties `((upstream-name . "Rmpi")))
    (build-system r-build-system)
    (arguments
     `(#:configure-flags '("--configure-args=\"--with-Rmpi-type=OPENMPI\"")
       #:phases (modify-phases %standard-phases
                  (add-before 'install 'mpi-setup
                    ,%openmpi-setup))))
    (inputs
     `(("openmpi" ,openmpi)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "http://www.stats.uwo.ca/faculty/yu/Rmpi")
    (synopsis "R interface to message-passing interface (MPI)")
    (description
     "This package provides an interface (wrapper) to MPI APIs.  It also
provides an interactive R manager and worker environment.")
    (license license:gpl2+)))

(define-public r-lmoments
  (package
    (name "r-lmoments")
    (version "1.3-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Lmoments" version))
       (sha256
        (base32
         "0pc63bj9a8hzr5m3yssrc4kin39fffwkl8rggs3sagzr12d4i7bw"))))
    (properties `((upstream-name . "Lmoments")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "http://www.tilastotiede.fi/juha_karvanen.html")
    (synopsis "L-moments and quantile mixtures")
    (description
     "This package contains functions to estimate L-moments and trimmed
L-moments from the data.  It also contains functions to estimate the
parameters of the normal polynomial quantile mixture and the Cauchy polynomial
quantile mixture from L-moments and trimmed L-moments.")
    (license license:gpl2)))

(define-public r-distillery
  (package
    (name "r-distillery")
    (version "1.0-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "distillery" version))
       (sha256
        (base32
         "1mi3ig9jq0kd7yrwc5m37lmrw04p1b4lirnbsxi10z3n5yay4429"))))
    (build-system r-build-system)
    (home-page "https://ral.ucar.edu/staff/ericg/")
    (synopsis "Functions for confidence intervals and object information")
    (description
     "This package provides some very simple method functions for confidence
interval calculation and to distill pertinent information from a potentially
complex object; primarily used in common with the packages extRemes and
SpatialVx.")
    (license license:gpl2+)))

(define-public r-extremes
  (package
    (name "r-extremes")
    (version "2.0-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "extRemes" version))
       (sha256
        (base32
         "0hmgynxhzswqnhwb2sxrkczgam8c17s3vpxqc5bcz0bwczpxxyvm"))))
    (properties `((upstream-name . "extRemes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-distillery" ,r-distillery)
       ("r-lmoments" ,r-lmoments)))
    (home-page "https://www.assessment.ucar.edu/toolkit/")
    (synopsis "Extreme value analysis")
    (description
     "ExtRemes is a suite of functions for carrying out analyses on the
extreme values of a process of interest; be they block maxima over long blocks
or excesses over a high threshold.")
    (license license:gpl2+)))

(define-public r-lmtest
  (package
    (name "r-lmtest")
    (version "0.9-37")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lmtest" version))
       (sha256
        (base32
         "02nasm0j2vwkhz11dxqixs23msy1s3yj0jps6949fmgh9gwjkjfx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-zoo" ,r-zoo)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/lmtest")
    (synopsis "Testing linear regression models")
    (description
     "This package provides a collection of tests, data sets, and examples for
diagnostic checking in linear regression models.  Furthermore, some generic
tools for inference in parametric models are provided.")
    ;; Either version is okay
    (license (list license:gpl2 license:gpl3))))

(define-public r-idr
  (package
    (name "r-idr")
    (version "1.2")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "idr" version))
              (sha256
               (base32
                "05nvgw1xdg670bsjjrxkgd1mrdkciccpw4krn0zcgdf2r21dzgwb"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/idr/")
    (synopsis "Irreproducible discovery rate")
    (description
     "This is a package for estimating the copula mixture model and plotting
correspondence curves in \"Measuring reproducibility of high-throughput
experiments\" (2011), Annals of Applied Statistics, Vol. 5, No. 3, 1752-1779,
by Li, Brown, Huang, and Bickel")
    (license license:gpl2+)))

(define-public r-inline
  (package
    (name "r-inline")
    (version "0.3.15")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "inline" version))
              (sha256
               (base32
                "0s4wssvpan189fijahknxq5s22ww9bzmdlmyhnra748r7khky17z"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/inline")
    (synopsis "Functions to inline C, C++, Fortran function calls from R")
    (description
     "This package provides functionality to dynamically define R functions
and S4 methods with inlined C, C++ or Fortran code supporting @code{.C} and
@code{.Call} calling conventions.")
    ;; Any version of the LGPL.
    (license license:lgpl3+)))

(define-public r-bdsmatrix
  (package
    (name "r-bdsmatrix")
    (version "1.3-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bdsmatrix" version))
       (sha256
        (base32
         "1sh6pg43rgqvips4fx0k4vmp5i9lmniix0bqwj2yq5m06gs227i5"))))
    (properties `((upstream-name . "bdsmatrix")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/bdsmatrix/")
    (synopsis "Routines for block diagonal symmetric matrices")
    (description
     "This package provides procedures to work with block diagonal symmetric
matrices, a special case of sparse matrices.")
    (license license:lgpl2.0)))

(define-public r-bbmle
  (package
    (name "r-bbmle")
    (version "1.0.23.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bbmle" version))
       (sha256
        (base32
         "0p3l9shbr2846qmw8n0fyzf4j7gmi08aypl82jml3dwh26q1whk0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bdsmatrix" ,r-bdsmatrix)
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-numderiv" ,r-numderiv)))
    (home-page "https://cran.r-project.org/web/packages/bbmle")
    (synopsis "Tools for General Maximum Likelihood Estimation")
    (description
     "This package provides methods and functions for fitting maximum
likelihood models in R.  This package modifies and extends the @code{mle}
classes in the @code{stats4} package.")
    ;; Any version of the GPL
    (license license:gpl2+)))

(define-public r-emdbook
  (package
    (name "r-emdbook")
    (version "1.3.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "emdbook" version))
       (sha256
        (base32
         "0ls3zxxlwmdv7zn1v9i1y9zc2sn0hbgmyjvsj7zn3ajsw7wwlih6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bbmle" ,r-bbmle)
       ("r-coda" ,r-coda)
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-plyr" ,r-plyr)))
    (home-page "http://www.math.mcmaster.ca/bolker/emdbook")
    (synopsis "Support functions and data for \"Ecological Models and Data\"")
    (description
     "This package provides auxiliary functions and data sets for \"Ecological
Models and Data\", a book presenting maximum likelihood estimation and related
topics for ecologists (ISBN 978-0-691-12522-0).")
    ;; Any GPL version
    (license (list license:gpl2 license:gpl3))))

(define-public r-lpsolve
  (package
    (name "r-lpsolve")
    (version "5.6.15")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lpSolve" version))
       (sha256
        (base32
         "1fpkyjyqykwa1dxnhiky01pm09syxg169lm7hpy39bdbg10vw9s6"))))
    (properties `((upstream-name . "lpSolve")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/lpSolve")
    (synopsis "R interface to Lp_solve to solve linear/integer programs")
    (description
     "Lp_solve is software for solving linear, integer and mixed integer
programs.  This implementation supplies a \"wrapper\" function in C and some R
functions that solve general linear/integer problems, assignment problems, and
transportation problems.")
    (license license:lgpl2.0)))

(define-public r-limsolve
  (package
    (name "r-limsolve")
    (version "1.5.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "limSolve" version))
       (sha256
        (base32
         "1829rd2cnd8qj80z9a7sgc7gx4sf3kvl5g6d2a0lqqw30f9sjzmr"))))
    (properties `((upstream-name . "limSolve")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lpsolve" ,r-lpsolve)
       ("r-mass" ,r-mass)
       ("r-quadprog" ,r-quadprog)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/limSolve")
    (synopsis "Solving linear inverse models")
    (description
     "This package provides functions that:

@enumerate
@item find the minimum/maximum of a linear or quadratic function,
@item sample an underdetermined or overdetermined system,
@item solve a linear system Ax=B for the unknown x.
@end enumerate

It includes banded and tridiagonal linear systems.  The package calls Fortran
functions from LINPACK.")
    ;; Any GPL version.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-fitdistrplus
  (package
    (name "r-fitdistrplus")
    (version "1.0-14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fitdistrplus" version))
       (sha256
        (base32
         "10q08wsv8v3w7797jdvvv60bgrf1bi6438wf0jcqv81ays82a245"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-npsurv" ,r-npsurv)
       ("r-survival" ,r-survival)))
    (home-page "http://riskassessment.r-forge.r-project.org")
    (synopsis "Fitting a parametric distribution from data")
    (description
     "This package extends the @code{fitdistr} function of the MASS package
with several functions to help the fit of a parametric distribution to
non-censored or censored data.  Censored data may contain left-censored,
right-censored and interval-censored values, with several lower and upper
bounds.  In addition to @dfn{maximum likelihood estimation} (MLE), the package
provides moment matching (MME), quantile matching (QME) and maximum
goodness-of-fit estimation (MGE) methods (available only for non-censored
data).  Weighted versions of MLE, MME and QME are available.")
    (license license:gpl2+)))

(define-public r-energy
  (package
    (name "r-energy")
    (version "1.7-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "energy" version))
       (sha256
        (base32
         "13wnx5nwk7nsv7vf5sxhz4y0rxrnzm76ldgywk1bxrz67srqzf37"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/energy")
    (synopsis "Multivariate inference via the energy of data")
    (description
     "This package provides e-statistics (energy) tests and statistics for
multivariate and univariate inference, including distance correlation,
one-sample, two-sample, and multi-sample tests for comparing multivariate
distributions, are implemented.  Measuring and testing multivariate
independence based on distance correlation, partial distance correlation,
multivariate goodness-of-fit tests, clustering based on energy distance,
testing for multivariate normality, distance components (disco) for
non-parametric analysis of structured data, and other energy
statistics/methods are implemented.")
    (license license:gpl2+)))

(define-public r-suppdists
  (package
    (name "r-suppdists")
    (version "1.1-9.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SuppDists" version))
       (sha256
        (base32
         "01j6p94m1g363nph2158fq2rmd6z3h5dvcv6aidh2d6syw131xak"))))
    (properties `((upstream-name . "SuppDists")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/SuppDists")
    (synopsis "Supplementary distributions")
    (description
     "This package provides ten distributions supplementing those built into
R.  Inverse Gauss, Kruskal-Wallis, Kendall's Tau, Friedman's chi squared,
Spearman's rho, maximum F ratio, the Pearson product moment correlation
coefficient, Johnson distributions, normal scores and generalized
hypergeometric distributions.  In addition two random number generators of
George Marsaglia are included.")
    (license license:gpl2+)))

(define-public r-ksamples
  (package
    (name "r-ksamples")
    (version "1.2-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kSamples" version))
       (sha256
        (base32
         "1zs22p68d6320kcylisnk0b5wmpapxkyz15py09czxzw7npw8gms"))))
    (properties `((upstream-name . "kSamples")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-suppdists" ,r-suppdists)))
    (home-page "https://cran.r-project.org/web/packages/kSamples")
    (synopsis "K-Sample rank tests and their combinations")
    (description
     "This package provides tools to compares k samples using the
Anderson-Darling test, Kruskal-Wallis type tests with different rank score
criteria, Steel's multiple comparison test, and the Jonckheere-Terpstra (JT)
test.  It computes asymptotic, simulated or (limited) exact P-values, all
valid under randomization, with or without ties, or conditionally under random
sampling from populations, given the observed tie pattern.  Except for Steel's
test and the JT test it also combines these tests across several blocks of
samples.")
    (license license:gpl2+)))

(define-public r-cvst
  (package
    (name "r-cvst")
    (version "0.2-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "CVST" version))
       (sha256
        (base32
         "05l3yzkfrbds09ah9cdwn2sn4ryhq78lz33ryzrgkv176jc8qjw5"))))
    (properties `((upstream-name . "CVST")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-kernlab" ,r-kernlab)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/CVST")
    (synopsis "Fast cross-validation via sequential testing")
    (description
     "This package implements the fast cross-validation via sequential
testing (CVST) procedure.  CVST is an improved cross-validation procedure
which uses non-parametric testing coupled with sequential analysis to
determine the best parameter set on linearly increasing subsets of the data.
Additionally to the CVST the package contains an implementation of the
ordinary k-fold cross-validation with a flexible and powerful set of helper
objects and methods to handle the overall model selection process.  The
implementations of the Cochran's Q test with permutations and the sequential
testing framework of Wald are generic and can therefore also be used in other
contexts.")
    (license license:gpl2+)))

(define-public r-squarem
  (package
    (name "r-squarem")
    (version "2020.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SQUAREM" version))
       (sha256
        (base32
         "1j6sa93xjvynnzx9jx79a3fysbykmbqyknknsqif5bcha6xp6cvf"))))
    (properties `((upstream-name . "SQUAREM")))
    (build-system r-build-system)
    (home-page "https://coah.jhu.edu/people/Faculty_personal_Pages/Varadhan.html")
    (synopsis "Squared Extrapolation Methods for Accelerating EM-Like Monotone Algorithms")
    (description
     "This package provides algorithms for accelerating the convergence of
slow, monotone sequences from smooth, contraction mapping such as the EM
algorithm.  It can be used to accelerate any smooth, linearly convergent
acceleration scheme.  A tutorial style introduction to this package is
available in a vignette.")
    (license license:gpl2+)))

(define-public r-lava
  (package
    (name "r-lava")
    (version "1.6.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lava" version))
       (sha256
        (base32
         "0ffzxbb8pvfh1m6j61az4ga37snyhylq2941fyc76w7w9i2sixv3"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-numderiv" ,r-numderiv)
       ("r-squarem" ,r-squarem)
       ("r-survival" ,r-survival)))
    (home-page "https://github.com/kkholst/lava")
    (synopsis "Latent variable models")
    (description
     "This package provides tools for the estimation and simulation of latent
variable models.")
    (license license:gpl3)))

(define-public r-drr
  (package
    (name "r-drr")
    (version "0.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "DRR" version))
       (sha256
        (base32
         "1y70si1gig4l7jx5jiqsqliyywfsvimkx53x3zh1lc3yj2j6bqwk"))))
    (properties `((upstream-name . "DRR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cvst" ,r-cvst)
       ("r-kernlab" ,r-kernlab)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/DRR")
    (synopsis "Dimensionality reduction via regression")
    (description
     "This package provides an implementation of dimensionality reduction via
regression using Kernel Ridge Regression.")
    (license license:gpl3)))

(define-public r-prodlim
  (package
    (name "r-prodlim")
    (version "2019.11.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "prodlim" version))
       (sha256
        (base32
         "03wvh3kirp1prac5nky6a5whs97rvaf4hc27x0fnh51sa17r42b8"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-kernsmooth" ,r-kernsmooth)
       ("r-lava" ,r-lava)
       ("r-rcpp" ,r-rcpp)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/prodlim")
    (synopsis "Product-limit estimation for censored event history analysis")
    (description
     "This package provides a fast and user-friendly implementation of
nonparametric estimators for censored event history (survival) analysis with
the Kaplan-Meier and Aalen-Johansen methods.")
    (license license:gpl2+)))

(define-public r-dimred
  (package
    (name "r-dimred")
    (version "0.2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dimRed" version))
       (sha256
        (base32
         "110d6y83ib1nfpxzmvkvb3fn3brskwkdbsk4dqrdrswrd4znxrg6"))))
    (properties `((upstream-name . "dimRed")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-drr" ,r-drr)
       ("r-magrittr" ,r-magrittr)))
    (home-page "https://github.com/gdkrmr/dimRed")
    (synopsis "Framework for dimensionality reduction")
    (description
     "This package provides a collection of dimensionality reduction
techniques from R packages and provides a common interface for calling the
methods.")
    (license license:gpl3)))

(define-public r-timedate
  (package
    (name "r-timedate")
    (version "3043.102")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "timeDate" version))
       (sha256
        (base32
         "0wvl5pq261rvbgly7vilk3x3m9xk3ly6il1i5scwdf6srl1vlz1p"))))
    (properties `((upstream-name . "timeDate")))
    (build-system r-build-system)
    (home-page "https://www.rmetrics.org")
    (synopsis "Chronological and calendar objects")
    (description
     "This package provides an environment for teaching \"Financial
Engineering and Computational Finance\" and for managing chronological and
calendar objects.")
    (license license:gpl2+)))

(define-public r-magic
  (package
    (name "r-magic")
    (version "1.5-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "magic" version))
       (sha256
        (base32
         "0snmdh6vk0p6ar1swsihisinxrx7l8371dri5lk0z24ysgr5w7gs"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)))
    (home-page "https://github.com/RobinHankin/magic.git")
    (synopsis "Create and investigate magic squares")
    (description
     "This package provides a collection of efficient, vectorized algorithms
for the creation and investigation of magic squares and hypercubes, including
a variety of functions for the manipulation and analysis of arbitrarily
dimensioned arrays.")
    (license license:gpl2)))

(define-public r-rmysql
  (package
    (name "r-rmysql")
    (version "0.10.20")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RMySQL" version))
       (sha256
        (base32
         "0lv9m6zpm8dgv7yixr6xhw379vbq45d7n7gkrmjrppdj8vcih77i"))))
    (properties `((upstream-name . "RMySQL")))
    (build-system r-build-system)
    (inputs
     `(("mariadb" ,mariadb "lib")
       ("mariadb-dev" ,mariadb "dev")
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-dbi" ,r-dbi)))
    (home-page "https://github.com/r-dbi/RMySQL")
    (synopsis "Database interface and MySQL driver for R")
    (description
     "This package provides a DBI interface to MySQL / MariaDB.  The RMySQL
package contains an old implementation based on legacy code from S-PLUS which
is being phased out.  A modern MySQL client based on Rcpp is available from
the RMariaDB package.")
    (license license:gpl2)))

(define-public r-rpostgresql
  (package
    (name "r-rpostgresql")
    (version "0.6-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RPostgreSQL" version))
       (sha256
        (base32
         "1mdhw5821v2h7hpa53v10wz53k4i90r0vb6a3dia5gq8f9j1h088"))))
    (properties `((upstream-name . "RPostgreSQL")))
    (build-system r-build-system)
    (inputs
     `(("postgresql" ,postgresql)))
    (propagated-inputs
     `(("r-dbi" ,r-dbi)))
    (home-page "https://github.com/tomoakin/RPostgreSQL")
    (synopsis "R interface to the PostgreSQL database system")
    (description
     "This package provides a Database Interface (DBI) compliant driver for R
to access PostgreSQL database systems.")
    ;; The whole package is released under GPL version 2.  It includes code
    ;; under the PostgreSQL license.
    (license license:gpl2)))

(define-public r-linprog
  (package
    (name "r-linprog")
    (version "0.9-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "linprog" version))
       (sha256
        (base32
         "1ki14an0pmhs2mnmfjjvdzd76pshiyvi659zf7hqvqwj0viv4dw9"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-lpsolve" ,r-lpsolve)))
    (home-page "http://linprog.r-forge.r-project.org/")
    (synopsis "Linear programming and optimization")
    (description
     "This package can be used to solve Linear Programming / Linear
Optimization problems by using the simplex algorithm.")
    (license license:gpl2+)))

(define-public r-geometry
  (package
    (name "r-geometry")
    (version "0.4.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "geometry" version))
       (sha256
        (base32
         "1n10l8ax3783v3lgaacb15qsn8b3f0wpmhg3k39j31s6ciyd3vcg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-magic" ,r-magic)
       ("r-linprog" ,r-linprog)
       ("r-lpsolve" ,r-lpsolve)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppprogress" ,r-rcppprogress)))
    (home-page "http://geometry.r-forge.r-project.org/")
    (synopsis "Mesh generation and surface tesselation")
    (description
     "This package makes the qhull library available in R, in a similar manner
as in Octave.  Qhull computes convex hulls, Delaunay triangulations, halfspace
intersections about a point, Voronoi diagrams, furthest-site Delaunay
triangulations, and furthest-site Voronoi diagrams.  It runs in 2-d, 3-d, 4-d,
and higher dimensions.  It implements the Quickhull algorithm for computing
the convex hull.  Qhull does not support constrained Delaunay triangulations,
or mesh generation of non-convex objects, but the package does include some R
functions that allow for this.  Currently the package only gives access to
Delaunay triangulation and convex hull computation.")
    ;; The Qhull sources are included and are distributed under a custom
    ;; non-copyleft license.  The R sources are released under GPL version 2.
    (license (list license:gpl2
                   (license:non-copyleft "http://www.qhull.org/COPYING.txt")))))

(define-public r-ddalpha
  (package
    (name "r-ddalpha")
    (version "1.3.11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ddalpha" version))
       (sha256
        (base32
         "1sdnb47r534nh138zk3a6b2mgi74nvshc7p5m304vjs9jlx4l2y3"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-class" ,r-class)
       ("r-geometry" ,r-geometry)
       ("r-mass" ,r-mass)
       ("r-rcpp" ,r-rcpp)
       ("r-robustbase" ,r-robustbase)
       ("r-sfsmisc" ,r-sfsmisc)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/ddalpha")
    (synopsis "Depth-Based classification and calculation of data depth")
    (description
     "This package contains procedures for depth-based supervised learning,
which are entirely non-parametric, in particular the DDalpha-procedure (Lange,
Mosler and Mozharovskyi, 2014).  The training data sample is transformed by a
statistical depth function to a compact low-dimensional space, where the final
classification is done.  It also offers an extension to functional data and
routines for calculating certain notions of statistical depth functions.  50
multivariate and 5 functional classification problems are included.")
    (license license:gpl2)))

(define-public r-gower
  (package
    (name "r-gower")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gower" version))
       (sha256
        (base32
         "007ivwn1nagpi26qq8iih1c2l61c53glvv60n90hi341ry8vwgxg"))))
    (build-system r-build-system)
    (home-page "https://github.com/markvanderloo/gower")
    (synopsis "Gower's distance")
    (description
     "This package provides tools to compute Gower's distance (or similarity)
coefficient between records, and to compute the top-n matches between records.
Core algorithms are executed in parallel on systems supporting OpenMP.")
    (license license:gpl3)))

(define-public r-rcpproll
  (package
    (name "r-rcpproll")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RcppRoll" version))
       (sha256
        (base32
         "0srzfhzkk42kzrdjnhbb37946jp1p688rgysy6k3i2is8jb21zyb"))))
    (properties `((upstream-name . "RcppRoll")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/RcppRoll")
    (synopsis "Efficient rolling and windowed operations")
    (description
     "This package provides fast and efficient routines for common rolling /
windowed operations.  Routines for the efficient computation of windowed mean,
median, sum, product, minimum, maximum, standard deviation and variance are
provided.")
    (license license:gpl2+)))

(define-public r-ipred
  (package
    (name "r-ipred")
    (version "0.9-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ipred" version))
       (sha256
        (base32
         "0vs1hqfx7yd0xdbmfsf2gim7spkni0845cj6gswn0nhdfdq7ma0d"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-class" ,r-class)
       ("r-mass" ,r-mass)
       ("r-nnet" ,r-nnet)
       ("r-prodlim" ,r-prodlim)
       ("r-rpart" ,r-rpart)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/ipred")
    (synopsis "Improved predictors")
    (description
     "This package provides improved predictive models by indirect
classification and bagging for classification, regression and survival
problems as well as resampling based estimators of prediction error.")
    (license license:gpl2+)))

(define-public r-psych
  (package
    (name "r-psych")
    (version "1.9.12.31")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "psych" version))
       (sha256
        (base32
         "02i9p6appf15hjdsi58g39bzs9as40f9qhy8m7ki30hd1fz1vrr5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)
       ("r-mnormt" ,r-mnormt)
       ("r-nlme" ,r-nlme)))
    (home-page "https://cran.r-project.org/web/packages/psych/")
    (synopsis "Procedures for psychological, psychometric, and personality research")
    (description
     "This package provides a general purpose toolbox for personality,
psychometric theory and experimental psychology.  Functions are primarily for
multivariate analysis and scale construction using factor analysis, principal
component analysis, cluster analysis and reliability analysis, although others
provide basic descriptive statistics.  Item Response Theory is done using
factor analysis of tetrachoric and polychoric correlations.  Functions for
analyzing data at multiple levels include within and between group statistics,
including correlations and factor analysis.  Functions for simulating and
testing particular item and test structures are included.  Several functions
serve as a useful front end for structural equation modeling.  Graphical
displays of path diagrams, factor analysis and structural equation models are
created using basic graphics.")
    (license license:gpl2+)))

(define-public r-generics
  (package
    (name "r-generics")
    (version "0.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "generics" version))
       (sha256
        (base32
         "0xk1xhpy7gpv3pvaygzhpfdxj72zmb38pb4nscfyg2ff36vx3cvi"))))
    (build-system r-build-system)
    (home-page "https://github.com/r-lib/generics")
    (synopsis "Common S3 generics not provided by base R methods")
    (description
     "In order to reduce potential package dependencies and conflicts,
generics provides a number of commonly used S3 generics that are not provided
by base R methods related to model fitting.")
    (license license:gpl2)))

(define-public r-broom
  (package
    (name "r-broom")
    (version "0.5.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "broom" version))
       (sha256
        (base32
         "0n7zd64263kfavdi28rl2bxrsa00c3m4vjhhjdrfwvvmrcxj39fx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-backports" ,r-backports)
       ("r-dplyr" ,r-dplyr)
       ("r-generics" ,r-generics)
       ("r-nlme" ,r-nlme)
       ("r-purrr" ,r-purrr)
       ("r-reshape2" ,r-reshape2)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/tidyverse/broom")
    (synopsis "Convert statistical analysis objects into tidy data frames")
    (description
     "This package provides tools to convert statistical analysis objects from
R into tidy data frames, so that they can more easily be combined, reshaped
and otherwise processed with tools like @code{dplyr}, @code{tidyr} and
@code{ggplot2}.  The package provides three S3 generics: @code{tidy}, which
summarizes a model's statistical findings such as coefficients of a
regression; @code{augment}, which adds columns to the original data such as
predictions, residuals and cluster assignments; and @code{glance}, which
provides a one-row summary of model-level statistics.")
    (license license:expat)))

(define-public r-recipes
  (package
    (name "r-recipes")
    (version "0.1.10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "recipes" version))
       (sha256
        (base32
         "11f96aanrzi2v6cn49fhvf9y4cmhra63wcy6nvpv6hcfaqqmwd2g"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-generics" ,r-generics)
       ("r-glue" ,r-glue)
       ("r-gower" ,r-gower)
       ("r-ipred" ,r-ipred)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-matrix" ,r-matrix)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)
       ("r-tidyselect" ,r-tidyselect)
       ("r-timedate" ,r-timedate)
       ("r-withr" ,r-withr)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/topepo/recipes")
    (synopsis "Preprocessing tools to create design matrices")
    (description
     "Recipes is an extensible framework to create and preprocess design
matrices.  Recipes consist of one or more data manipulation and analysis
\"steps\".  Statistical parameters for the steps can be estimated from an
initial data set and then applied to other data sets.  The resulting design
matrices can then be used as inputs into statistical or machine learning
models.")
    (license license:gpl2)))

(define-public r-pdist
  (package
    (name "r-pdist")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pdist" version))
       (sha256
        (base32
         "18nd3mgad11f2zmwcp0w3sxlch4a9y6wp8dfdyzvjn7y4b4bq0dd"))))
    (build-system r-build-system)
    (home-page "https://github.com/jeffwong/pdist")
    (synopsis "Partitioned distance function")
    (description
     "Pdist computes the euclidean distance between rows of a matrix X and
rows of another matrix Y.  Previously, this could be done by binding the two
matrices together and calling @code{dist}, but this creates unnecessary
computation by computing the distances between a row of X and another row of
X, and likewise for Y.  Pdist strictly computes distances across the two
matrices, not within the same matrix, making computations significantly faster
for certain use cases.")
    (license license:gpl3+)))

(define-public r-ggrepel
  (package
    (name "r-ggrepel")
    (version "0.8.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggrepel" version))
       (sha256
        (base32
         "1qaifn3dazdqbqlii210xhw7yf142iw7g9p2axmmxbz90p0by08d"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-rcpp" ,r-rcpp)
       ("r-scales" ,r-scales)))
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "http://github.com/slowkow/ggrepel")
    (synopsis "Repulsive text and label geometries for ggplot2")
    (description
     "This package provides text and label geometries for ggplot2 that help to
avoid overlapping text labels.  Labels repel away from each other and away
from the data points.")
    (license license:gpl3)))

(define-public r-corrplot
  (package
    (name "r-corrplot")
    (version "0.84")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "corrplot" version))
       (sha256
        (base32
         "1k03qd8db7pwg1v318xapx5mpiypiz2n07qr19c4b45diri5xkhd"))))
    (build-system r-build-system)
    (home-page "https://github.com/taiyun/corrplot")
    (synopsis "Visualization of a correlation matrix")
    (description
     "This package provides a graphical display of a correlation matrix or
general matrix.  It also contains some algorithms to do matrix reordering.  In
addition, corrplot is good at details, including choosing color, text labels,
color labels, layout, etc.")
    ;; Any version of the GPL
    (license license:gpl2+)))

(define-public r-stringdist
  (package
    (name "r-stringdist")
    (version "0.9.5.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "stringdist" version))
       (sha256
        (base32 "1dqfakclzaf878x7mhwmqrcpcql2h9cv19fz5f3ygpajf3si5kqi"))))
    (build-system r-build-system)
    (home-page "https://github.com/markvanderloo/stringdist")
    (synopsis "Approximate string matching and string distance functions")
    (description
     "This package implements an approximate string matching version of R's
native @code{match} function.  It can calculate various string distances based
on edits (Damerau-Levenshtein, Hamming, Levenshtein, optimal sting alignment),
qgrams (q- gram, cosine, jaccard distance) or heuristic metrics (Jaro,
Jaro-Winkler).  An implementation of soundex is provided as well.  Distances
can be computed between character vectors while taking proper care of encoding
or between integer vectors representing generic sequences.")
    (license license:gpl3+)))

(define-public r-ucminf
  (package
    (name "r-ucminf")
    (version "1.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ucminf" version))
       (sha256
        (base32
         "01vggwg1w71k98qs6fhb0x1843vi322mf4g3hbclks94kcpkisx2"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/ucminf/")
    (synopsis "General-purpose unconstrained non-linear optimization")
    (description
     "This package provides an implementation of an algorithm for
general-purpose unconstrained non-linear optimization.  The algorithm is of
quasi-Newton type with BFGS updating of the inverse Hessian and soft line
search with a trust region type monitoring of the input to the line search
algorithm.  The interface of @code{ucminf} is designed for easy interchange
with the package @code{optim}.")
    (license license:gpl2+)))

(define-public r-ordinal
  (package
    (name "r-ordinal")
    (version "2019.12-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ordinal" version))
       (sha256
        (base32
         "09bpmjmbf4x82kgf6bm4bkncq2apdv9mk20zj4zgma2jx2vyfhbs"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-numderiv" ,r-numderiv)
       ("r-ucminf" ,r-ucminf)))
    (home-page "https://github.com/runehaubo/ordinal")
    (synopsis "Regression models for ordinal data")
    (description
     "This package provides an implementation of cumulative link (mixed)
models also known as ordered regression models, proportional odds models,
proportional hazards models for grouped survival times and ordered models.
Estimation is via maximum likelihood and mixed models are fitted with the
Laplace approximation and adaptive Gauss-Hermite quadrature.")
    (license license:gpl2+)))

(define-public r-jomo
  (package
    (name "r-jomo")
    (version "2.6-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "jomo" version))
       (sha256
        (base32
         "1k9l4290g350zbw1pjs871q9bxj3j2h1dilxpp06v4wy4n7d8qs0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lme4" ,r-lme4)
       ("r-mass" ,r-mass)
       ("r-ordinal" ,r-ordinal)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/jomo/")
    (synopsis "Multilevel Joint Modelling Multiple Imputation")
    (description
     "Similarly to Schafer's package pan, jomo is a package for multilevel
joint modelling multiple imputation @url{Carpenter and Kenward (2013),
http://doi.org/10.1002/9781119942283}.  Novel aspects of jomo are the
possibility of handling binary and categorical data through latent normal
variables, the option to use cluster-specific covariance matrices and to
impute compatibly with the substantive model.")
    (license license:gpl2)))

(define-public r-pan
  (package
    (name "r-pan")
    (version "1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pan" version))
       (sha256
        (base32
         "1dk3jjj826p7xrz10qz04vyc068xnypg7bp0pj4c32z3da0xzh5d"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/pan/")
    (synopsis "Multiple imputation for multivariate panel or clustered data")
    (description
     "This package implements multiple imputation for multivariate panel or
clustered data.")
    (license license:gpl3)))

(define-public r-mitml
  (package
    (name "r-mitml")
    (version "0.3-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mitml" version))
       (sha256
        (base32
         "0yqyxkyi1kmv5k63wxj5kkg5g8igk1axk2csb4xhj6wz0p89dxy6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-haven" ,r-haven)
       ("r-jomo" ,r-jomo)
       ("r-pan" ,r-pan)))
    (home-page "https://cran.r-project.org/web/packages/mitml/")
    (synopsis "Tools for multiple imputation in multilevel modeling")
    (description
     "This package provides tools for multiple imputation of missing data in
multilevel modeling.  It includes a user-friendly interface to the packages
pan and jomo, and several functions for visualization, data management and the
analysis of multiply imputed data sets.")
    (license license:gpl2+)))

(define-public r-mice
  (package
    (name "r-mice")
    (version "3.8.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mice" version))
       (sha256
        (base32
         "1ibybvigqkkla4xwhqs2w4m6c68alfcdsljx99nn4p92rzb1ig04"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-broom" ,r-broom)
       ("r-dplyr" ,r-dplyr)
       ("r-lattice" ,r-lattice)
       ("r-rcpp" ,r-rcpp)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://cran.r-project.org/web/packages/mice/")
    (synopsis "Multivariate imputation by chained equations")
    (description
     "Multiple imputation using @dfn{Fully Conditional Specification} (FCS)
implemented by the MICE algorithm as described in @url{Van Buuren and
Groothuis-Oudshoorn (2011), http://doi.org/10.18637/jss.v045.i03}.  Each
variable has its own imputation model.  Built-in imputation models are
provided for continuous data (predictive mean matching, normal), binary
data (logistic regression), unordered categorical data (polytomous logistic
regression) and ordered categorical data (proportional odds).  MICE can also
impute continuous two-level data (normal model, pan, second-level variables).
Passive imputation can be used to maintain consistency between variables.
Various diagnostic plots are available to inspect the quality of the
imputations.")
    ;; Any of these two versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-truncnorm
  (package
    (name "r-truncnorm")
    (version "1.0-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "truncnorm" version))
       (sha256
        (base32
         "0zn88wdd58223kibk085rhsikl4yhlrwiyq109hzjg06hy6lwmj9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/truncnorm/")
    (synopsis "Truncated normal distribution")
    (description "This package provides functions for the truncated normal
distribution with mean equal to @code{mean} and standard deviation equal to
@code{sd}.  It includes density, distribution, quantile, and expected value
functions, as well as a random generation function.")
    (license license:gpl2)))

(define-public r-rsolnp
  (package
    (name "r-rsolnp")
    (version "1.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rsolnp" version))
       (sha256
        (base32
         "0w7nkj6igr0gi7r7jg950lsx7dj6aipgxi6vbjsf5f5yc9h7fhii"))))
    (properties `((upstream-name . "Rsolnp")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-truncnorm" ,r-truncnorm)))
    (home-page "https://cran.r-project.org/web/packages/Rsolnp/")
    (synopsis "General non-linear optimization")
    (description "The Rsolnp package implements a general non-linear augmented
Lagrange multiplier method solver, a @dfn{sequential quadratic
programming} (SQP) based solver).")
    ;; Any version of the GPL.
    (license license:gpl2+)))

(define-public r-hardyweinberg
  (package
    (name "r-hardyweinberg")
    (version "1.6.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "HardyWeinberg" version))
       (sha256
        (base32
         "1irz44q6nf95h37av868f47aakwv3jgwgw217xfsfw0afkm7s25f"))))
    (properties `((upstream-name . "HardyWeinberg")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mice" ,r-mice)
       ("r-rcpp" ,r-rcpp)
       ("r-rsolnp" ,r-rsolnp)))
    (home-page "https://cran.r-project.org/package=HardyWeinberg")
    (synopsis "Statistical tests and graphics for Hardy-Weinberg equilibrium")
    (description
     "This package contains tools for exploring Hardy-Weinberg equilibrium for
diallelic genetic marker data.  All classical tests (chi-square, exact,
likelihood-ratio and permutation tests) for Hardy-Weinberg equilibrium are
included in the package, as well as functions for power computation and for
the simulation of marker data under equilibrium and disequilibrium.  Routines
for dealing with markers on the X-chromosome are included.  Functions for
testing equilibrium in the presence of missing data by using multiple
imputation are also provided.  Implements several graphics for exploring the
equilibrium status of a large set of diallelic markers: ternary plots with
acceptance regions, log-ratio plots and Q-Q plots.")
    (license license:gpl2+)))

(define-public r-sm
  (package
    (name "r-sm")
    (version "2.2-5.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sm" version))
       (sha256
        (base32
         "0c4whcx879gb4lwvqnzxl5n9xgpcqh2c54ip9ami3mwfprzcv45q"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "http://www.stats.gla.ac.uk/~adrian/sm/")
    (synopsis "Smoothing methods for nonparametric regression and density estimation")
    (description
     "This is software accompanying the book 'Applied Smoothing Techniques for
Data Analysis---The Kernel Approach with S-Plus Illustrations', Oxford
University Press.  It provides smoothing methods for nonparametric regression
and density estimation")
    (license license:gpl2+)))

(define-public r-venndiagram
  (package
    (name "r-venndiagram")
    (version "1.6.20")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "VennDiagram" version))
              (sha256
               (base32
                "1ic1jaxzw98si2p4n1fl4n3myhd7fpw0njb634cwhviwybzv6775"))))
    (properties `((upstream-name . "VennDiagram")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-futile-logger" ,r-futile-logger)))
    (home-page "https://cran.r-project.org/web/packages/VennDiagram/")
    (synopsis "Generate High-Resolution Venn and Euler Plots")
    (description
     "This package provides a set of functions to generate high-resolution
Venn and Euler plots.  It includes handling for several special cases,
including two-case scaling, and extensive customization of plot shape and
structure.")
    (license license:gpl2+)))

(define-public r-vioplot
  (package
    (name "r-vioplot")
    (version "0.3.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "vioplot" version))
       (sha256
        (base32
         "1fsklymilspzz5fzlj7666x09aglaw0v4x0yfjjzy4vr5qpjc529"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-sm" ,r-sm)
       ("r-zoo" ,r-zoo)))
    (home-page "http://wsopuppenkiste.wiso.uni-goettingen.de/~dadler")
    (synopsis "Violin plot")
    (description
     "This package provides a violin plot, which is a combination of a box
plot and a kernel density plot.")
    (license license:bsd-3)))

(define-public r-rsofia
  (package
    (name "r-rsofia")
    (version "1.1")
    (source (origin
              (method url-fetch)
              ;; This package has been removed from CRAN, so we can
              ;; only fetch it from the archives.
              (uri (string-append "https://cran.r-project.org/src/"
                                  "contrib/Archive/RSofia/RSofia_"
                                  version ".tar.gz"))
              (sha256
               (base32
                "0q931y9rcf6slb0s2lsxhgqrzy4yqwh8hb1124nxg0bjbxvjbihn"))))
    (properties `((upstream-name . "RSofia")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/src/contrib/Archive/RSofia")
    (synopsis "Port of sofia-ml to R")
    (description "This package is a port of sofia-ml to R.  Sofia-ml is a
suite of fast incremental algorithms for machine learning that can be used for
training models for classification or ranking.")
    (license license:asl2.0)))

(define-public r-xts
  (package
    (name "r-xts")
    (version "0.12-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xts" version))
       (sha256
        (base32
         "0q4cc8ynp7ndmgll1jj3lxyl6wmgg89ad3wq09kjc2ngszdfc4fz"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-zoo" ,r-zoo)))
    (home-page "https://github.com/joshuaulrich/xts")
    (synopsis "Extensible time series")
    (description
     "This package provides for uniform handling of R's different time-based
data classes by extending @code{zoo}, maximizing native format information
preservation and allowing for user-level customization and extension, while
simplifying cross-class interoperability.")
    (license license:gpl2+)))

(define-public r-performanceanalytics
  (package
    (name "r-performanceanalytics")
    (version "2.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "PerformanceAnalytics" version))
       (sha256
        (base32
         "0ci26hsj4wnw9g0mh4vrn0cg986cpcpx169rvw6v6rbnjxq718bq"))))
    (properties
     `((upstream-name . "PerformanceAnalytics")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quadprog" ,r-quadprog)
       ("r-xts" ,r-xts)
       ("r-zoo" ,r-zoo)))
    (home-page "https://r-forge.r-project.org/projects/returnanalytics/")
    (synopsis "Econometric tools for performance and risk analysis")
    (description "This is a collection of econometric functions for
performance and risk analysis.  This package aims to aid practitioners and
researchers in utilizing the latest research in analysis of non-normal return
streams.  In general, it is most tested on return (rather than price) data on
a regular scale, but most functions will work with irregular return data as
well, and increasing numbers of functions will work with P&L or price data
where possible.")
    ;; Either version may be picked.
    (license (list license:gpl2 license:gpl3))))

(define-public r-laeken
  (package
    (name "r-laeken")
    (version "0.5.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "laeken" version))
       (sha256
        (base32
         "199rjkhjjygpr6cjzab87as46acb5npi44m4yycvk7lnd0blma8s"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/laeken/")
    (synopsis "Estimation of indicators on social exclusion and poverty")
    (description "This package provides tools for the estimation of indicators
on social exclusion and poverty, as well as an implementation of Pareto tail
modeling for empirical income distributions.")
    (license license:gpl2+)))

(define-public r-vcd
  (package
    (name "r-vcd")
    (version "1.4-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "vcd" version))
       (sha256
        (base32
         "0rjz49py5l6wnaimw6k8rcyzlvs8cyz5g2xwqj2qis92ly0l103z"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colorspace" ,r-colorspace)
       ("r-lmtest" ,r-lmtest)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/vcd/")
    (synopsis "Visualizing categorical data")
    (description "This package provides visualization techniques, data sets,
summary and inference procedures aimed particularly at categorical data.
Special emphasis is given to highly extensible grid graphics.  The package was
originally inspired by the book \"Visualizing Categorical Data\" by Michael
Friendly and is now the main support package for a new book, \"Discrete Data
Analysis with R\" by Michael Friendly and David Meyer (2015).")
    (license license:gpl2)))

(define-public r-ica
  (package
    (name "r-ica")
    (version "1.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ica" version))
       (sha256
        (base32
         "0ya1nph1zwhad0bfz4yxs27kl45yk1dhnphdlrq34p8pqrpmj8g7"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ica/")
    (synopsis "Independent component analysis")
    (description "This package provides tools for @dfn{Independent Component
Analysis} (ICA) using various algorithms: FastICA,
Information-Maximization (Infomax), and @dfn{Joint Approximate Diagonalization
of Eigenmatrices} (JADE).")
    (license license:gpl2+)))

(define-public r-dtw
  (package
    (name "r-dtw")
    (version "1.21-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dtw" version))
       (sha256
        (base32
         "02hyhx1sy5h3vzh9zixy18a7d47df4k5d0wyflcvlcbsbcl6p90s"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-proxy" ,r-proxy)))
    (home-page "http://dtw.r-forge.r-project.org/")
    (synopsis "Dynamic Time Warping Algorithms")
    (description "This package provides a comprehensive implementation of
@dfn{dynamic time warping} (DTW) algorithms in R.  DTW computes the
optimal (least cumulative distance) alignment between points of two time
series.  Common DTW variants covered include local (slope) and global (window)
constraints, subsequence matches, arbitrary distance definitions,
normalizations, minimum variance matching, and so on.")
    (license license:gpl2+)))

(define-public r-sdmtools
  (package
    (name "r-sdmtools")
    (version "1.1-221.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SDMTools" version))
       (sha256
        (base32
         "1xvcd97ikqsfdpk2fddy3k0z1ajqga7nv9bgac9c1wnjk1gqrpgh"))))
    (properties `((upstream-name . "SDMTools")))
    (build-system r-build-system)
    (propagated-inputs `(("r-r-utils" ,r-r-utils)))
    (home-page "https://www.rforge.net/SDMTools/")
    (synopsis "Species distribution modelling tools")
    (description "This package provides a set of tools for post processing
the outcomes of species distribution modeling exercises.  It includes novel
methods for comparing models and tracking changes in distributions through
time.  It further includes methods for visualizing outcomes, selecting
thresholds, calculating measures of accuracy and landscape fragmentation
statistics, etc.")
    (license license:gpl3+)))

(define-public r-scatterplot3d
  (package
    (name "r-scatterplot3d")
    (version "0.3-41")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "scatterplot3d" version))
       (sha256
        (base32
         "152xqz9c70qab86mpgng049gxsg5f4fpf1m8dh93fb9v1avjd0sc"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/scatterplot3d/")
    (synopsis "3D scatter plot")
    (description "This package provides an implementation of scatter plots for
plotting.  a three dimensional point cloud.")
    (license license:gpl2)))

(define-public r-ggridges
  (package
    (name "r-ggridges")
    (version "0.5.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggridges" version))
       (sha256
        (base32
         "03pz257aw0mkh5k75rby9givkc1ky3n5scvhjhjiz9vry9fpffmh"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-plyr" ,r-plyr)
       ("r-scales" ,r-scales)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/clauswilke/ggridges")
    (synopsis "Ridgeline plots in ggplot2")
    (description
     "Ridgeline plots provide a convenient way of visualizing changes in
distributions over time or space.  This package enables the creation of such
plots in @code{ggplot2}.")
    (license license:gpl2)))

(define-public r-ggjoy
  (package
    (name "r-ggjoy")
    (version "0.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggjoy" version))
       (sha256
        (base32
         "012md2m0jqfcccb933j423m3ck31v3p0pd41gjxpyg9082y7ixyj"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-ggridges" ,r-ggridges)))
    (home-page "https://github.com/clauswilke/ggjoy")
    (synopsis "Joyplots in ggplot2")
    (description "Joyplots provide a convenient way of visualizing changes in
distributions over time or space.  This package enables the creation of such
plots in @code{ggplot2}.")
    (license license:gpl2)))

(define-public r-cli
  (package
    (name "r-cli")
    (version "2.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cli" version))
       (sha256
        (base32
         "1dhkah6jvr96k4h4agcc2rfls75bpjb0j58fzaz3dc0fp3jk8229"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-crayon" ,r-crayon)
       ("r-fansi" ,r-fansi)
       ("r-glue" ,r-glue)))
    (home-page "https://github.com/r-lib/cli#readme")
    (synopsis "Helpers for developing command line interfaces")
    (description "This package provides a suite of tools designed to build
attractive command line interfaces (CLIs).  It includes tools for drawing
rules, boxes, trees, and Unicode symbols with ASCII alternatives.")
    (license license:expat)))

(define-public r-argparser
  (package
    (name "r-argparser")
    (version "0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "argparser" version))
       (sha256
        (base32
         "1pxiz9jlhlnpzqn1lz349r07i7glw708w202x6dlnxp112fg7k4x"))))
    (build-system r-build-system)
    (home-page "https://bitbucket.org/djhshih/argparser")
    (synopsis "Command-line argument parser")
    (description
     "This package provides a cross-platform command-line argument parser
written purely in R with no external dependencies.  It is useful with the
Rscript front-end and facilitates turning an R script into an executable
script.")
    (license license:gpl3+)))

(define-public r-debugme
  (package
    (name "r-debugme")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "debugme" version))
       (sha256
        (base32
         "1c9sg55zvf10h8198jdnpamm6f66lzw3c3jnmdp9ls6na0j0xbjd"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-crayon" ,r-crayon)))
    (home-page "https://github.com/r-lib/debugme#readme")
    (synopsis "Debug R packages")
    (description
     "This package allows the user to specify debug messages as special string
constants, and control debugging of packages via environment variables.")
    (license license:expat)))

(define-public r-processx
  (package
    (name "r-processx")
    (version "3.4.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "processx" version))
       (sha256
        (base32
         "02awswxq6wh3rl99dncw5n6c1xmd0v81xcdp2dfyi6vm6b3gz84l"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ps" ,r-ps)
       ("r-r6" ,r-r6)))
    (home-page "https://github.com/r-lib/processx3")
    (synopsis "Execute and control system processes")
    (description
     "This package provides portable tools to run system processes in the
background.  It can check if a background process is running; wait on a
background process to finish; get the exit status of finished processes; kill
background processes and their children; restart processes.  It can read the
standard output and error of the processes, using non-blocking connections.
@code{processx} can poll a process for standard output or error, with a
timeout.  It can also poll several processes at once.")
    (license license:expat)))

(define-public r-tsp
  (package
    (name "r-tsp")
    (version "1.1-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TSP" version))
       (sha256
        (base32
         "183m6crb0dv17llj86059n3hbgsahbhfcqlx0ijdzkssg11i1cy7"))))
    (properties `((upstream-name . "TSP")))
    (build-system r-build-system)
    (propagated-inputs `(("r-foreach" ,r-foreach)))
    (home-page "https://cran.r-project.org/web/packages/TSP/")
    (synopsis "Traveling salesperson problem (TSP)")
    (description "This package provides basic infrastructure and some
algorithms for the @dfn{traveling salesperson problem}(TSP) (also known as the
traveling salesman problem).")
    (license license:gpl3)))

(define-public r-qap
  (package
    (name "r-qap")
    (version "0.1-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "qap" version))
       (sha256
        (base32
         "0d2d1ni1camixyi45lfy00f4pn3p063k7bsi8gj5scp6n15mdgb0"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/qap/")
    (synopsis "Heuristics for the quadratic assignment problem (QAP)")
    (description "This package implements heuristics for the @dfn{quadratic
assignment problem} (QAP).  Currently only a simulated annealing heuristic is
available.")
    (license license:gpl3)))

(define-public r-gclus
  (package
    (name "r-gclus")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gclus" version))
       (sha256
        (base32
         "1cz0g0i972955hhaji30rx8448x7f3as7z1sww9i5h86ybgirilw"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-cluster" ,r-cluster)))
    (home-page "https://cran.r-project.org/web/packages/gclus/")
    (synopsis "Clustering graphics")
    (description "This package orders panels in scatterplot matrices and
parallel coordinate displays by some merit index.  It contains various indices
of merit, ordering functions, and enhanced versions of @code{pairs} and
@code{parcoord} which color panels according to their merit level.")
    (license license:gpl2+)))

(define-public r-webshot
  (package
    (name "r-webshot")
    (version "0.5.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "webshot" version))
       (sha256
        (base32
         "0gq4h8cw51z95yvsnf38kj5l58wgljkm0dalmi8mn1sp06bxr0zi"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-callr" ,r-callr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-magrittr" ,r-magrittr)))
    (home-page "https://github.com/wch/webshot/")
    (synopsis "Take screenshots of web pages")
    (description
     "Webshot makes it easy to take screenshots of web pages from within R.
It can also run Shiny applications locally and take screenshots of the
application; and it can render and screenshot static as well as interactive R
Markdown documents.")
    (license license:gpl2)))

(define-public r-seriation
  (package
    (name "r-seriation")
    (version "1.2-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "seriation" version))
       (sha256
        (base32
         "1zbdxq0s5rc5v307b69fw9k52m0654ls7pf22lh35ggirig6lwsk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cluster" ,r-cluster)
       ("r-colorspace" ,r-colorspace)
       ("r-dendextend" ,r-dendextend)
       ("r-gclus" ,r-gclus)
       ("r-gplots" ,r-gplots)
       ("r-mass" ,r-mass)
       ("r-qap" ,r-qap)
       ("r-registry" ,r-registry)
       ("r-tsp" ,r-tsp)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://s2.smu.edu/IDA/seriation/")
    (synopsis "Infrastructure for ordering objects using seriation")
    (description
     "This package provides infrastructure for seriation with an
implementation of several seriation/sequencing techniques to reorder matrices,
dissimilarity matrices, and dendrograms.  It also provides (optimally)
reordered heatmaps, color images and clustering visualizations like
dissimilarity plots, and visual assessment of cluster tendency plots (VAT and
iVAT).")
    (license license:gpl3)))

(define-public r-xfun
  (package
    (name "r-xfun")
    (version "0.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xfun" version))
       (sha256
        (base32 "0sgh8kafi9x1glmmcp1ly827pm8q7fsfngbplr41fbb4nc9363df"))))
    (build-system r-build-system)
    (home-page "https://github.com/yihui/xfun")
    (synopsis "Miscellaneous functions")
    (description
     "This package provides miscellaneous functions commonly used in other
packages maintained by Yihui Xie.")
    (license license:expat)))

(define-public r-utf8
  (package
    (name "r-utf8")
    (version "1.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "utf8" version))
       (sha256
        (base32
         "0m0ywg8k3blfiahxvh1i4zn9dksrlc937d2lbza5fc38zjnrrnpn"))))
    (build-system r-build-system)
    (home-page "https://github.com/patperry/r-utf8")
    (synopsis "Unicode text processing")
    (description
     "This package provides tools to process and print UTF-8 encoded
international text (Unicode).  Input, validate, normalize, encode, format, and
display.")
    (license license:asl2.0)))

(define-public r-zeallot
  (package
    (name "r-zeallot")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "zeallot" version))
       (sha256
        (base32
         "1sd1igcfnv27pa3bqxlbyxchi562h7grnjg1l7wxx3bwr49i57s3"))))
    (build-system r-build-system)
    (home-page "https://github.com/nteetor/zeallot")
    (synopsis "Multiple, unpacking, and destructuring assignment")
    (description
     "This package provides a @code{%<-%} operator to perform multiple,
unpacking, and destructuring assignment in R.  The operator unpacks the
right-hand side of an assignment into multiple values and assigns these values
to variables on the left-hand side of the assignment.")
    (license license:expat)))

(define-public r-vctrs
  (package
    (name "r-vctrs")
    (version "0.2.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "vctrs" version))
       (sha256
        (base32
         "15sgzs6afvmhssk6jcg41rn3bvmzmbm4sgca6f6x8lfrsazvdj6w"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-ellipsis" ,r-ellipsis)
       ("r-glue" ,r-glue)
       ("r-rlang" ,r-rlang)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/r-lib/vctrs")
    (synopsis "Vector helpers")
    (description
     "There are three main goals to the @code{vctrs} package:

@enumerate
@item To propose @code{vec_size()} and @code{vec_type()} as alternatives to
  @code{length()} and @code{class()}.  These definitions are paired with a
  framework for type-coercion and size-recycling.
@item To define type- and size-stability as desirable function properties, use
  them to analyse existing base function, and to propose better alternatives.
  This work has been particularly motivated by thinking about the ideal
  properties of @code{c()}, @code{ifelse()}, and @code{rbind()}.
@item To provide a new @code{vctr} base class that makes it easy to create new
  S3 vectors.  @code{vctrs} provides methods for many base generics in terms of
  a few new @code{vctrs} generics, making implementation considerably simpler
  and more robust.
@end enumerate\n")
    (license license:gpl3)))

(define-public r-pillar
  (package
    (name "r-pillar")
    (version "1.4.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pillar" version))
       (sha256
        (base32
         "02sn7zw80wq33jgxk2i6m5jb83sk7y72dfhgyy0apfinv05w92ss"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cli" ,r-cli)
       ("r-crayon" ,r-crayon)
       ("r-fansi" ,r-fansi)
       ("r-rlang" ,r-rlang)
       ("r-utf8" ,r-utf8)
       ("r-vctrs" ,r-vctrs)))
    (home-page "https://github.com/r-lib/pillar")
    (synopsis "Coloured formatting for columns")
    (description
     "This package provides a @code{pillar} generic designed for formatting
columns of data using the full range of colours provided by modern
terminals.")
    (license license:gpl3)))

(define-public r-uuid
  (package
    (name "r-uuid")
    (version "0.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "uuid" version))
       (sha256
        (base32
         "0gm9ii7ncvllxbvyk6srsiinjmqyj7lmh84w43x4nhqpvafj9q4q"))))
    (build-system r-build-system)
    (home-page "https://www.rforge.net/uuid")
    (synopsis "Tools for generating and handling of UUIDs")
    (description
     "This package provides tools for generating and handling of
@dfn{Universally Unique Identifiers} (UUIDs).")
    (license license:expat)))

(define-public r-tinytex
  (package
    (name "r-tinytex")
    (version "0.20")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tinytex" version))
       (sha256
        (base32
         "0n8v8inpsc99r0snvqbjhqlc6nm9hxjsw120hrxc2mw03pa5fvkg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-xfun" ,r-xfun)))
    (home-page "https://github.com/yihui/tinytex")
    (synopsis "Helper functions for TeX Live and compiling LaTeX documents")
    (description
     "This package provides helper functions to install and maintain the LaTeX
distribution named TinyTeX, a lightweight, cross-platform, portable, and
easy-to-maintain version of TeX Live.  This package also contains helper
functions to compile LaTeX documents, and install missing LaTeX packages
automatically.")
    (license license:expat)))

(define-public r-network
  (package
    (name "r-network")
    (version "1.16.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "network" version))
       (sha256
        (base32
         "0dnf1wl3za2lhx2lwd8smhlijl1cfhckgr8zz9piiirrfi2m2kx2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-magrittr" ,r-magrittr)
       ("r-tibble" ,r-tibble)))
    (home-page "https://statnet.org/")
    (synopsis "Classes for relational data")
    (description
     "This package provides tools to create and modify network objects.  The
@code{network} class can represent a range of relational data types, and
supports arbitrary vertex/edge/graph attributes.")
    (license license:gpl2+)))

(define-public r-statnet-common
  (package
    (name "r-statnet-common")
    (version "4.3.0")
    (source
      (origin
        (method url-fetch)
        (uri (cran-uri "statnet.common" version))
        (sha256
          (base32
            "0ng90i0wm9wlyhjbnmnylc1bbqw396p1dr7f402dyry9x9ck6jl3"))))
    (properties
      `((upstream-name . "statnet.common")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-coda" ,r-coda)))
    (home-page "https://statnet.org")
    (synopsis "R scripts and utilities used by the Statnet software")
    (description "This package provides non-statistical utilities used by the
software developed by the Statnet Project.")
    (license license:gpl3)))

(define-public r-statcheck
  (package
    (name "r-statcheck")
    (version "1.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "statcheck" version))
       (sha256
        (base32
         "0ivybdcrymlsfv6pg6p5bv70qdvgxf2vgp0kf4r0pf2fcvav1mcp"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-plyr" ,r-plyr)
       ("r-rmarkdown" ,r-rmarkdown)))
    (home-page "https://cran.r-project.org/web/packages/statcheck/")
    (synopsis "Extract statistics from articles and recompute p-values")
    (description "This package can automatically extract statistical
null-hypothesis significant testing (NHST) results from articles and recompute
the p-values based on the reported test statistic and degrees of freedom to
detect possible inconsistencies.")
    (license license:gpl2)))

(define-public r-sna
  (package
    (name "r-sna")
    (version "2.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sna" version))
       (sha256
        (base32
         "1j3i6300m686qqfmyvadim377cd3mplzgj6mandygw8brg50id8k"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-network" ,r-network)
       ("r-statnet-common" ,r-statnet-common)))
    (home-page "https://statnet.org")
    (synopsis "Tools for social network analysis")
    (description
     "This package provides a range of tools for social network analysis,
including node and graph-level indices, structural distance and covariance
methods, structural equivalence detection, network regression, random graph
generation, and 2D/3D network visualization.")
    (license license:gpl2+)))

(define-public r-tfisher
  (package
    (name "r-tfisher")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TFisher" version))
       (sha256
        (base32
         "0vz74ww1lf1prfwz74hfsi3a8nzq8ss7aqjr85c1d87vss2796xx"))))
    (properties `((upstream-name . "TFisher")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-sn" ,r-sn)))
    (home-page "https://cran.r-project.org/web/packages/TFisher/")
    (synopsis "Optimal thresholding Fisher's p-value combination method")
    (description
     "This package provides the @dfn{cumulative distribution function} (CDF),
quantile, and statistical power calculator for a collection of thresholding
Fisher's p-value combination methods, including Fisher's p-value combination
method, truncated product method and, in particular, soft-thresholding
Fisher's p-value combination method which is proven to be optimal in some
context of signal detection.  The p-value calculator for the omnibus version
of these tests are also included.")
    (license license:gpl2)))

(define-public r-ttr
  (package
    (name "r-ttr")
    (version "0.23-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TTR" version))
       (sha256
        (base32
         "0rg22ma3x07s9djlxscfw5jcq1gbir05cwhgvwfi53x1sf4hmhdg"))))
    (properties `((upstream-name . "TTR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-xts" ,r-xts)
       ("r-zoo" ,r-zoo)))
    (home-page "https://github.com/joshuaulrich/TTR")
    (synopsis "Technical trading rules")
    (description
     "This package provides functions and data to construct technical trading
rules with R.")
    (license license:gpl2)))

(define-public r-leaps
  (package
    (name "r-leaps")
    (version "3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "leaps" version))
       (sha256
        (base32
         "1dn3yl1p03n0iynd1vsdkrr0fhmvgrmfkv37y7n371765h83lz1x"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/leaps/")
    (synopsis "Regression subset selection")
    (description
     "This package provides tools for regression subset selection, including
exhaustive search.")
    (license license:gpl2+)))

(define-public r-splus2r
  (package
    (name "r-splus2r")
    (version "1.2-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "splus2R" version))
       (sha256
        (base32
         "0xrbj8vxy0pc6hl7m8abv71d3hjw47cl51s7j7priadyqczkq6sz"))))
    (properties `((upstream-name . "splus2R")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/splus2R/")
    (synopsis "Supplemental S-PLUS functionality in R")
    (description
     "Currently there are many functions in S-PLUS that are missing in R.  To
facilitate the conversion of S-PLUS packages to R packages, this package
provides some missing S-PLUS functionality in R.")
    (license license:gpl2)))

(define-public r-ifultools
  (package
    (name "r-ifultools")
    (version "2.0-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ifultools" version))
       (sha256
        (base32
         "040kvbczcmmbaiaz0k0pdq9af541pjj6iwzh1a3w4szh9w6b5a3j"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-splus2r" ,r-splus2r)))
    (home-page "https://cran.r-project.org/web/packages/ifultools/")
    (synopsis "Insightful research tools")
    (description "This package provides C code used by the wmtsa, fractal, and
sapa R packages.")
    (license license:gpl2)))

(define-public r-sapa
  (package
    (name "r-sapa")
    (version "2.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sapa" version))
       (sha256
        (base32
         "056xlh14dnzq4x7sbp7ff2k61jxy7110a742b502vz549qfrr5ds"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ifultools" ,r-ifultools)
       ("r-splus2r" ,r-splus2r)))
    (home-page "https://cran.r-project.org/web/packages/sapa/")
    (synopsis "Spectral analysis for physical applications")
    (description "This package provides software for the book Spectral
Analysis for Physical Applications, Donald B. Percival and Andrew T. Walden,
Cambridge University Press, 1993.")
    (license license:gpl2)))

(define-public r-aggregation
  (package
    (name "r-aggregation")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "aggregation" version))
       (sha256
        (base32
         "0j9g604m2ccc7hcy02539yja9cf3xcbl25gvp838bp4x8w18my46"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/aggregation/")
    (synopsis "Methods for p-value aggregation")
    (description
     "This package contains functionality for performing the following methods
of p-value aggregation: Fisher's method, the Lancaster method (weighted
Fisher's method), and Sidak correction.")
    (license license:gpl3)))

(define-public r-quantmod
  (package
    (name "r-quantmod")
    (version "0.4-16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "quantmod" version))
       (sha256
        (base32
         "12l5br8abr1yagxqjnjvqzp79sqsv5vx56cxs37gk73r474f4vc2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-ttr" ,r-ttr)
       ("r-xts" ,r-xts)
       ("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/quantmod/")
    (synopsis "Quantitative financial modelling framework")
    (description "This package provides a quantitative financial modelling
framework to allow users to specify, build, trade, and analyse quantitative
financial trading strategies.")
    (license license:gpl3)))

(define-public r-tseries
  (package
    (name "r-tseries")
    (version "0.10-47")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tseries" version))
       (sha256
        (base32
         "0yzvc9djp3angvxdxqi60wi726y76ablsb71q88ycvw0avgpf8r0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quadprog" ,r-quadprog)
       ("r-quantmod" ,r-quantmod)
       ("r-zoo" ,r-zoo)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/tseries/")
    (synopsis "Time series analysis and computational finance")
    (description
     "This package provides functions relating to time series analysis and
computational finance.")
    (license license:gpl2)))

(define-public r-wmtsa
  (package
    (name "r-wmtsa")
    (version "2.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "wmtsa" version))
       (sha256
        (base32
         "1q436krz5p1f4a7a7sya6a9rh9x9mi8zzcgq66gbk9w9w4hcqcj6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ifultools" ,r-ifultools)
       ("r-mass" ,r-mass)
       ("r-splus2r" ,r-splus2r)))
    (home-page "https://cran.r-project.org/web/packages/wmtsa/")
    (synopsis "Wavelet methods for time series analysis")
    (description
     "This package provides software to accompany the book \"Wavelet Methods
for Time Series Analysis\", Donald B. Percival and Andrew T. Walden, Cambridge
University Press, 2000.")
    (license license:gpl2)))

(define-public r-tsa
  (package
    (name "r-tsa")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TSA" version))
       (sha256
        (base32
         "0gjfqibwdznz0nka95k4fjm935svxjpnqfywwz403crn2lh30h6q"))))
    (properties `((upstream-name . "TSA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-leaps" ,r-leaps)
       ("r-locfit" ,r-locfit)
       ("r-mgcv" ,r-mgcv)))
    (home-page "https://homepage.divms.uiowa.edu/~kchan/TSA.htm")
    (synopsis "Time series analysis")
    (description
     "This package contains R functions and datasets detailed in the book
\"Time Series Analysis with Applications in R (second edition)\" by Jonathan
Cryer and Kung-Sik Chan.")
    (license license:gpl2+)))

(define-public r-extradistr
  (package
    (name "r-extradistr")
    (version "1.8.11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "extraDistr" version))
       (sha256
        (base32
         "1vvqv1d4hxa025gmm8cbiph63qsqy87l3ri5idd524gyz3chbcl3"))))
    (properties `((upstream-name . "extraDistr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/twolodzko/extraDistr")
    (synopsis "Additional univariate and multivariate distributions")
    (description
     "This package implements density, distribution functions, quantile
functions and random generation functions for a large number of univariate and
multivariate distributions.")
    (license license:gpl2)))

(define-public r-fractal
  (package
    (name "r-fractal")
    (version "2.0-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fractal" version))
       (sha256
        (base32
         "18lr9z0gslvfc3z8vyj3krqj3bfhg60zv1fzinrwwkc4cpk1w7mp"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ifultools" ,r-ifultools)
       ("r-mass" ,r-mass)
       ("r-sapa" ,r-sapa)
       ("r-scatterplot3d" ,r-scatterplot3d)
       ("r-splus2r" ,r-splus2r)
       ("r-wmtsa" ,r-wmtsa)))
    (home-page "https://cran.r-project.org/web/packages/fractal/")
    (synopsis "Fractal time series modeling and analysis")
    (description
     "This package provides tools for stochastic fractal and deterministic
chaotic time series analysis.")
    (license license:gpl2)))

(define-public r-urca
  (package
    (name "r-urca")
    (version "1.3-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "urca" version))
       (sha256
        (base32
         "1akaqwf3fvvvx4sgfn641fd4sj51s0701pvfl6s5hnz2k0iwh732"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-nlme" ,r-nlme)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/urca/")
    (synopsis "Unit root and cointegration tests for time series data")
    (description
     "This package provides unit root and cointegration tests encountered in
applied econometric analysis.")
    (license license:gpl2+)))

(define-public r-cubature
  (package
    (name "r-cubature")
    (version "2.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cubature" version))
       (sha256
        (base32
         "0jpyq8j7x06dpiz29w48av879ygldzgls9z810192hsymkmfaz6r"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/bnaras/cubature")
    (synopsis "Adaptive multivariate integration over hypercubes")
    (description
     "This package is an R wrapper around the cubature C library for adaptive
multivariate integration over hypercubes.  This version provides both
@code{hcubature} and @code{pcubature} routines in addition to a vector
interface.")
    ;; The included cubature C library is released under GPLv2+, but the
    ;; wrapper declares the license to be GPLv3+.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-trend
  (package
    (name "r-trend")
    (version "1.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "trend" version))
       (sha256
        (base32
         "09b6ycyfgs4xlhx6kn6qm5rl2acp58hzhv8qclzn3kb1wjjyvxy5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-extradistr" ,r-extradistr)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/trend/")
    (synopsis "Non-parametric trend tests and change-point detection")
    (description
     "The analysis of environmental data often requires the detection of
trends and change-points.  This package includes tests for trend
detection (Cox-Stuart Trend Test, Mann-Kendall Trend Test, (correlated)
Hirsch-Slack Test, partial Mann-Kendall Trend Test, multivariate (multisite)
Mann-Kendall Trend Test, (Seasonal) Sen's slope, partial Pearson and Spearman
correlation trend test), change-point detection (Lanzante's test procedures,
Pettitt's test, Buishand Range Test, Buishand U Test, Standard Normal
Homogeinity Test), detection of non-randomness (Wallis-Moore Phase Frequency
Test, Bartels rank von Neumann's ratio test, Wald-Wolfowitz Test) and the two
sample Robust Rank-Order Distributional Test.")
    (license license:gpl3)))

(define-public r-expm
  (package
    (name "r-expm")
    (version "0.999-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "expm" version))
       (sha256
        (base32
         "15k0acg2aqb2ajhwal6l7vhhp03m4lg579805d34554cl0kn9l2q"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-matrix" ,r-matrix)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://r-forge.r-project.org/projects/expm/")
    (synopsis "Tools for matrix exponentials and related quantities")
    (description
     "This package provides tools for the computation of the matrix
exponential, logarithm, square root, and related quantities.")
    (license license:gpl2+)))

(define-public r-complexplus
  (package
    (name "r-complexplus")
    (version "2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "complexplus" version))
       (sha256
        (base32
         "16w9v7d1ckavqmr86l34frr37pkvdn0iqnb17ssb8xaggns5lgqx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-expm" ,r-expm)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/complexplus/")
    (synopsis "Functions of complex or real variables")
    (description
     "This package extends several functions to the complex domain, including
the matrix exponential and logarithm, and the determinant.")
    (license license:gpl2)))

(define-public r-phontools
  (package
    (name "r-phontools")
    (version "0.2-2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "phonTools" version))
       (sha256
        (base32
         "01i481mhswsys3gpasw9gn6nxkfmi7bz46g5c84m13pg0cv8hxc7"))))
    (properties `((upstream-name . "phonTools")))
    (build-system r-build-system)
    (home-page "http://www.santiagobarreda.com/rscripts.html")
    (synopsis "Tools for phonetic and acoustic analyses")
    (description
     "This package contains tools for the organization, display, and analysis
of the sorts of data frequently encountered in phonetics research and
experimentation, including the easy creation of IPA vowel plots, and the
creation and manipulation of WAVE audio files.")
    (license license:bsd-2)))

(define-public r-np
  (package
    (name "r-np")
    (version "0.60-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "np" version))
       (sha256
        (base32
         "06h8k0kdv5s258jr6s08fabvlycrbs7iq34jk2f2hfmqm2y4nyx2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-cubature" ,r-cubature)
       ("r-quadprog" ,r-quadprog)
       ("r-quantreg" ,r-quantreg)))
    (home-page "https://github.com/JeffreyRacine/R-Package-np")
    (synopsis "Non-parametric kernel smoothing methods for mixed data types")
    (description "This package provides non-parametric (and semi-parametric)
kernel methods that seamlessly handle a mix of continuous, unordered, and
ordered factor data types.")
    ;; Any version of the GPL.
    (license license:gpl3+)))

(define-public r-powerplus
  (package
    (name "r-powerplus")
    (version "3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "powerplus" version))
       (sha256
        (base32
         "0ayp6x34hkzgris4j3zbbs0r23n81bhww3wgfyy630ri4sk6brrn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-complexplus" ,r-complexplus)
       ("r-expm" ,r-expm)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-phontools" ,r-phontools)))
    (home-page "https://cran.r-project.org/web/packages/powerplus/")
    (synopsis "Exponentiation operations")
    (description
     "This package provides tools for the computation of matrix and scalar
exponentiation.")
    (license license:gpl2)))

(define-public r-egg
  (package
    (name "r-egg")
    (version "0.4.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "egg" version))
       (sha256
        (base32
         "1fy7srpiavfn8kyrr1m84an7acgwi6ydzrg71m3b0vk7y9ybmj0m"))))
    (properties `((upstream-name . "egg")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-gtable" ,r-gtable)))
    (home-page "https://cran.r-project.org/web/packages/egg")
    (synopsis "Extensions for ggplot2")
    (description
     "This package provides miscellaneous functions to help customize ggplot2
objects.  High-level functions are provided to post-process ggplot2 layouts
and allow alignment between plot panels, as well as setting panel sizes to
fixed values.  Other functions include a custom @code{geom}, and helper
functions to enforce symmetric scales or add tags to facetted plots.")
    (license license:gpl3)))

(define-public r-heatmaply
  (package
    (name "r-heatmaply")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "heatmaply" version))
       (sha256
        (base32
         "0576gml3bcl7r1biigzj1rag2xzz422knbw7arc8d2gsakjj757g"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-colorspace" ,r-colorspace)
       ("r-dendextend" ,r-dendextend)
       ("r-egg" ,r-egg)
       ("r-ggplot2" ,r-ggplot2)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-magrittr" ,r-magrittr)
       ("r-plotly" ,r-plotly)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-reshape2" ,r-reshape2)
       ("r-scales" ,r-scales)
       ("r-seriation" ,r-seriation)
       ("r-viridis" ,r-viridis)
       ("r-webshot" ,r-webshot)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://cran.r-project.org/package=heatmaply")
    (synopsis "Interactive cluster heat maps using plotly")
    (description
     "This package enables you to create interactive cluster heatmaps that can
be saved as a stand-alone HTML file, embedded in R Markdown documents or in a
Shiny app, and made available in the RStudio viewer pane.  Hover the mouse
pointer over a cell to show details or drag a rectangle to zoom.  A heatmap is
a popular graphical method for visualizing high-dimensional data, in which a
table of numbers is encoded as a grid of colored cells.  The rows and columns
of the matrix are ordered to highlight patterns and are often accompanied by
dendrograms.")
    ;; Either version of the license.
    (license (list license:gpl2 license:gpl3))))

(define-public r-h5
  (package
    (name "r-h5")
    (version "0.9.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "h5" version))
       (sha256
        (base32
         "14p7i1sj24ky87kd7qr3n9fc9l64s0bp0rwbyl6i2x69xn75gpsx"))))
    (build-system r-build-system)
    (inputs
     `(("zlib" ,zlib)
       ("hdf5" ,hdf5)))
    (native-inputs
     `(("which" ,which)))
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/mannau/h5")
    (synopsis "Interface to the HDF5 Library")
    (description
     "This package provides an S4 interface to the HDF5 library supporting
fast storage and retrieval of R-objects like vectors, matrices and arrays to
binary files in a language independent format.  The HDF5 format can therefore
be used as an alternative to R's save/load mechanism.  Since h5 is able to
access only subsets of stored data it can also handle data sets which do not
fit into memory.")
    (license license:bsd-2)))

(define-public r-cgdsr
  (package
    (name "r-cgdsr")
    (version "1.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cgdsr" version))
       (sha256
        (base32
         "07yc819hkabpzzh0g0cbqza6bcfy67b2marrzz1lj97f9iba78ja"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-httr" ,r-httr)
       ("r-r-methodss3" ,r-r-methodss3)
       ("r-r-oo" ,r-r-oo)))
    (home-page "https://github.com/cBioPortal/cgdsr")
    (synopsis "R-based API for accessing the MSKCC Cancer Genomics Data Server")
    (description
     "This package provides a basic set of R functions for querying the Cancer
Genomics Data Server (CGDS), hosted by the Computational Biology Center at
Memorial-Sloan-Kettering Cancer Center (MSKCC).")
    (license license:lgpl3)))

(define-public r-import
  (package
    (name "r-import")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "import" version))
       (sha256
        (base32
         "0blf9539rbfwcmw8zsb4k58slb4pdnc075v34vmyjw752fznhcji"))))
    (build-system r-build-system)
    (home-page "https://github.com/smbache/import")
    (synopsis "Import mechanism for R")
    (description
     "This is an alternative mechanism for importing objects from packages.
The syntax allows for importing multiple objects from a package with a single
command in an expressive way.  The import package bridges some of the gap
between using @code{library} (or @code{require}) and direct (single-object)
imports.  Furthermore the imported objects are not placed in the current
environment.  It is also possible to import objects from stand-alone @code{.R}
files.")
    (license license:expat)))

(define-public r-shinyace
  (package
    (name "r-shinyace")
    (version "0.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinyAce" version))
       (sha256
        (base32
         "1m33dfm2kjirvgix7ybv1kbzgjkicdpv411g9c0q3fw6rnyhfxxn"))))
    (properties `((upstream-name . "shinyAce")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-shiny" ,r-shiny)
       ("r-jsonlite" ,r-jsonlite)))
    (home-page "https://cran.r-project.org/web/packages/shinyAce/")
    (synopsis "Ace editor bindings for Shiny")
    (description
     "This package provides Ace editor bindings to enable a rich text editing
environment within Shiny.")
    (license license:expat)))

(define-public r-randomizr
  (package
    (name "r-randomizr")
    (version "0.20.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "randomizr" version))
       (sha256
        (base32
         "0dljyfldnardaps3fq6vi5wcs9x6qfaq5apapa78c51lnaa6fn9h"))))
    (properties `((upstream-name . "randomizr")))
    (build-system r-build-system)
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://declaredesign.org/r/randomizr/")
    (synopsis "Tools for common forms of random assignment and sampling")
    (description
     "This package provides tools for generating random assignments for common
experimental designs and random samples for common sampling designs.")
    (license license:expat)))

(define-public r-base64url
  (package
    (name "r-base64url")
    (version "1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "base64url" version))
       (sha256
        (base32
         "0n1c2b68vza1dh7sk38v6biiwm72c4jpl79kpdg1bsb0hq9qy18x"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-backports" ,r-backports)))
    (home-page "https://github.com/mllg/base64url")
    (synopsis "Fast and URL-safe base64 encoder and decoder")
    (description
     "This package provides a URL-safe base64 encoder and decoder.  In
contrast to RFC3548, the 62nd character (@code{+}) is replaced with @code{-},
the 63rd character (@code{/}) is replaced with @code{_}.  Furthermore, the
encoder does not fill the string with trailing @code{=}.  The resulting
encoded strings comply to the regular expression pattern @code{[A-Za-z0-9_-]}
and thus are safe to use in URLs or for file names.  The package also comes
with a simple base32 encoder/decoder suited for case insensitive file
systems.")
    (license license:gpl3)))

(define-public r-radiant-data
  (package
    (name "r-radiant-data")
    (version "1.3.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "radiant.data" version))
       (sha256
        (base32
         "19sjjb49inrfl7jzq4zpwhdslni0zrp30bl58pisin29ka3ylpzs"))
       (modules '((guix build utils)))
       (snippet
        '(begin
           ;; Delete files that are under CC-NC-SA.
           (delete-file-recursively "inst/app/tools/help")
           #t))))
    (properties `((upstream-name . "radiant.data")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-broom" ,r-broom)
       ("r-car" ,r-car)
       ("r-curl" ,r-curl)
       ("r-dplyr" ,r-dplyr)
       ("r-dt" ,r-dt)
       ("r-glue" ,r-glue)
       ("r-ggplot2" ,r-ggplot2)
       ("r-import" ,r-import)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-markdown" ,r-markdown)
       ("r-mass" ,r-mass)
       ("r-patchwork" ,r-patchwork)
       ("r-plotly" ,r-plotly)
       ("r-psych" ,r-psych)
       ("r-randomizr" ,r-randomizr)
       ("r-readr" ,r-readr)
       ("r-readxl" ,r-readxl)
       ("r-rlang" ,r-rlang)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-scales" ,r-scales)
       ("r-shiny" ,r-shiny)
       ("r-shinyfiles" ,r-shinyfiles)
       ("r-shinyace" ,r-shinyace)
       ("r-stringi" ,r-stringi)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)
       ("r-writexl" ,r-writexl)))
    (home-page "https://github.com/radiant-rstats/radiant.data")
    (synopsis "Data menu for Radiant: business analytics using R and Shiny")
    (description
     "The Radiant Data menu includes interfaces for loading, saving, viewing,
visualizing, summarizing, transforming, and combining data.  It also contains
functionality to generate reproducible reports of the analyses conducted in
the application.")
    (license license:agpl3)))

(define-public r-algdesign
  (package
    (name "r-algdesign")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AlgDesign" version))
       (sha256
        (base32 "0ammlg148gk0p24fh700116nd66636np0jb1wwh0axq5jphwk1pz"))))
    (properties `((upstream-name . "AlgDesign")))
    (build-system r-build-system)
    (home-page "https://github.com/jvbraun/AlgDesign")
    (synopsis "Algorithmic experimental design")
    (description
     "This package provides tools to calculate exact and approximate theory
experimental designs for D, A, and I criteria.  Very large designs may be
created.  Experimental designs may be blocked or blocked designs created from
a candidate list, using several criteria.  The blocking can be done when whole
and within plot factors interact.")
    (license license:gpl2+)))

(define-public r-signal
  (package
    (name "r-signal")
    (version "0.7-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "signal" version))
       (sha256
        (base32
         "1vsxramz5qd9q9s3vlqzmfdpmwl2rhlb2n904zw6f0fg0xxjfq3b"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/signal/")
    (synopsis "Signal processing")
    (description
     "This package provides a set of signal processing functions originally
written for Matlab and GNU Octave.  It includes filter generation utilities,
filtering functions, resampling routines, and visualization of filter models.
It also includes interpolation functions.")
    (license license:gpl2)))

(define-public r-gsubfn
  (package
    (name "r-gsubfn")
    (version "0.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gsubfn" version))
       (sha256
        (base32
         "00j6b8b6xsx6v370h220x233rpk6asca78165y3d48jpwvwisdc9"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-proto" ,r-proto)))
    (home-page "https://code.google.com/archive/p/gsubfn/")
    (synopsis "Utilities for strings and function arguments.")
    (description
     "This package provides @code{gsubfn} which is like @code{gsub} but can
take a replacement function or certain other objects instead of the
replacement string.  Matches and back references are input to the replacement
function and replaced by the function output.  @code{gsubfn} can be used to
split strings based on content rather than delimiters and for quasi-perl-style
string interpolation.  The package also has facilities for translating
formulas to functions and allowing such formulas in function calls instead of
functions.")
    (license license:gpl2+)))

(define-public r-sqldf
  (package
    (name "r-sqldf")
    (version "0.4-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sqldf" version))
       (sha256
        (base32
         "0q12vsb53p2wchgp8wfz5bk08wfnm0jxjrakclj4jyy6x3a7ksff"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-chron" ,r-chron)
       ("r-dbi" ,r-dbi)
       ("r-gsubfn" ,r-gsubfn)
       ("r-proto" ,r-proto)
       ("r-rsqlite" ,r-rsqlite)))
    (home-page "https://github.com/ggrothendieck/sqldf")
    (synopsis "Manipulate R data frames using SQL")
    (description
     "The @code{sqldf} function is typically passed a single argument which is
an SQL select statement where the table names are ordinary R data frame names.
@code{sqldf} transparently sets up a database, imports the data frames into
that database, performs the SQL statement and returns the result using a
heuristic to determine which class to assign to each column of the returned
data frame.  The @code{sqldf} or @code{read.csv.sql} functions can also be
used to read filtered files into R even if the original files are larger than
R itself can handle.")
    (license license:gpl2)))

(define-public r-abind
  (package
    (name "r-abind")
    (version "1.4-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abind" version))
       (sha256
        (base32
         "0b1zd8jbnl6l292cr9rb50m09fy3ylxvzkpgi5lfb1nbzddcwfis"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/abind/")
    (synopsis "Combine multidimensional arrays")
    (description
     "This package provides tools to combine multidimensional arrays into a
single array.  This is a generalization of @code{cbind} and @code{rbind}.  It
works with vectors, matrices, and higher-dimensional arrays.  It also provides
the functions @code{adrop}, @code{asub}, and @code{afill} for manipulating,
extracting and replacing data in arrays.")
    (license license:lgpl2.0+)))

(define-public r-prroc
  (package
    (name "r-prroc")
    (version "1.3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "PRROC" version))
       (sha256
        (base32
         "1m28h8pcd78049lz2qixhkcr9h5b3jik3maqzfbvq9y58z71i4a7"))))
    (properties `((upstream-name . "PRROC")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/PRROC/")
    (synopsis "Precision-Recall and ROC curves for weighted and unweighted data")
    (description
     "This package computes the areas under the @dfn{precision-recall} (PR)
and ROC curve for weighted (e.g. soft-labeled) and unweighted data.  In
contrast to other implementations, the interpolation between points of the PR
curve is done by a non-linear piecewise function.  In addition to the areas
under the curves, the curves themselves can also be computed and plotted by a
specific S3-method.")
    (license license:gpl3)))

(define-public r-vim
  (package
    (name "r-vim")
    (version "5.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "VIM" version))
       (sha256
        (base32
         "0w22ir0gvym7gqd6nw2j7w5ivlb3az1dkfxv33imimkb7c83056a"))))
    (properties `((upstream-name . "VIM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-car" ,r-car)
       ("r-colorspace" ,r-colorspace)
       ("r-data-table" ,r-data-table)
       ("r-e1071" ,r-e1071)
       ("r-laeken" ,r-laeken)
       ("r-magrittr" ,r-magrittr)
       ("r-mass" ,r-mass)
       ("r-nnet" ,r-nnet)
       ("r-ranger" ,r-ranger)
       ("r-rcpp" ,r-rcpp)
       ("r-robustbase" ,r-robustbase)
       ("r-sp" ,r-sp)
       ("r-vcd" ,r-vcd)))
    (home-page "https://github.com/alexkowa/VIM")
    (synopsis "Visualization and imputation of missing values")
    (description
     "This package provides tools for the visualization of missing and/or
imputed values are introduced, which can be used for exploring the data and
the structure of the missing and/or imputed values.  Depending on this
structure of the missing values, the corresponding methods may help to
identify the mechanism generating the missing values and allows to explore the
data including missing values.  In addition, the quality of imputation can be
visually explored using various univariate, bivariate, multiple and
multivariate plot methods.")
    (license license:gpl2+)))

(define-public r-fnn
  (package
    (name "r-fnn")
    (version "1.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "FNN" version))
       (sha256
        (base32
         "0cllqlnynm5yaj4r64mqyyfc8phkb38rwssq8k8ikgfgr4jklxny"))))
    (properties `((upstream-name . "FNN")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/FNN")
    (synopsis "Fast nearest neighbor search algorithms and applications")
    (description
     "This package provides cover-tree and kd-tree fast k-nearest neighbor
search algorithms.  Related applications including KNN classification,
regression and information measures are implemented.")
    ;; The DESCRIPTION file erroneously states that GPL version 2.1 or
    ;; later can be used.
    (license license:gpl2+)))

(define-public r-smoother
  (package
    (name "r-smoother")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "smoother" version))
       (sha256
        (base32
         "0nqr1bvlr5bnasqg74zmknjjl4x28kla9h5cxpga3kq5z215pdci"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ttr" ,r-ttr)))
    (home-page "https://cran.r-project.org/web/packages/smoother")
    (synopsis "Functions relating to the smoothing of numerical data")
    (description
     "This package provides a collection of methods for smoothing numerical
data, commencing with a port of the Matlab gaussian window smoothing function.
In addition, several functions typically used in smoothing of financial data
are included.")
    (license license:gpl2)))

(define-public r-riverplot
  (package
    (name "r-riverplot")
    (version "0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "riverplot" version))
       (sha256
        (base32
         "0q1icpny8nkxyjhawyjzwrw8qlz0ayn2xyrsqrm4vkxyv6c9xk8z"))))
    (build-system r-build-system)
    (home-page "https://logfc.wordpress.com")
    (synopsis "Sankey or ribbon plots")
    (description
     "Sankey plots are a type of diagram that is convenient to illustrate how
flow of information, resources etc. separates and joins, much like observing
how rivers split and merge.  For example, they can be used to compare
different clusterings.  This package provides an implementation of Sankey
plots for R.")
    (license license:gpl2+)))

(define-public r-dyn
  (package
    (name "r-dyn")
    (version "0.2-9.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dyn" version))
       (sha256
        (base32
         "16fqv9k7yxdgybwzafjkyqm16qpgqz13lcjpi6a1nc8xbzlzh0gb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/dyn")
    (synopsis "Time series regression")
    (description
     "This package provides the dyn class interfaces @code{ts}, @code{irts},
@code{zoo} and @code{zooreg} time series classes to @code{lm}, @code{glm},
@code{loess}, @code{quantreg::rq}, @code{MASS::rlm},
@code{MCMCpack::MCMCregress()}, @code{quantreg::rq()},
@code{randomForest::randomForest()} and other regression functions, allowing
those functions to be used with time series including specifications that may
contain lags, diffs and missing values.")
    ;; Any GPL version.
    (license license:gpl2+)))

(define-public r-catdap
  (package
    (name "r-catdap")
    (version "1.3.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "catdap" version))
       (sha256
        (base32
         "0fyhl69z2lznymvpzxra9qvcg85ggzkfjy68c6mzdmf1ja44d2k5"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/catdap/")
    (synopsis "Tools for categorical data analysis")
    (description
     "This package provides functions for analyzing multivariate data.
Dependencies of the distribution of the specified variable (response
variable) to other variables (explanatory variables) are derived and
evaluated by the @dfn{Akaike Information Criterion} (AIC).")
    (license license:gpl2+)))

(define-public r-arules
  (package
    (name "r-arules")
    (version "1.6-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "arules" version))
       (sha256
        (base32
         "003c5cd3xzq39h7c19px077ygm0n1v7k83icy5zzrnkagyds2p8n"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)))
    (home-page "https://github.com/mhahsler/arules")
    (synopsis "Mining association rules and frequent itemsets")
    (description
     "This package provides an infrastructure for representing, manipulating
and analyzing transaction data and patterns (frequent itemsets and association rules).
It also provides C implementations of the association mining algorithms Apriori
and Eclat.")
    (license license:gpl3)))

(define-public r-parsedate
  (package
    (name "r-parsedate")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "parsedate" version))
       (sha256
        (base32
         "0gb3w6hmwxayhijpf36p5dk4h6bbdps57x3cgikwvvxkgi83rarr"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rematch2" ,r-rematch2)))
    (home-page "https://github.com/gaborcsardi/parsedate")
    (synopsis
     "Recognize and parse dates in various formats")
    (description
     "This package provides three functions for dealing with dates:
@code{parse_iso_8601} recognizes and parses all valid ISO 8601 date and
time formats, @code{parse_date} parses dates in unspecified formats,
and @code{format_iso_8601} formats a date in ISO 8601 format.")
    (license license:gpl2)))

(define-public r-abc-data
  (package
    (name "r-abc-data")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abc.data" version))
       (sha256
        (base32
         "1bv1n68ah714ws58cf285n2s2v5vn7382lfjca4jxph57lyg8hmj"))))
    (properties `((upstream-name . "abc.data")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/abc.data/")
    (synopsis "Data for Approximate Bayesian Computation (ABC) package")
    (description
     "This package contains data which are used by functions of the abc
package which implements several @dfn{Approximate Bayesian Computation} (ABC)
algorithms for performing parameter estimation, model selection, and
goodness-of-fit.")
    (license license:gpl3+)))

(define-public r-abc
  (package
    (name "r-abc")
    (version "2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abc" version))
       (sha256
        (base32
         "0ngzaaz2y2s03fhngvwipmy4kq38xrmyddaz6a6l858rxvadrlhb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abc-data" ,r-abc-data)
       ("r-locfit" ,r-locfit)
       ("r-mass" ,r-mass)
       ("r-nnet" ,r-nnet)
       ("r-quantreg" ,r-quantreg)))
    (home-page "https://cran.r-project.org/web/packages/abc/")
    (synopsis "Tools for Approximate Bayesian Computation (ABC)")
    (description
     "This package implements several @dfn{Approximate Bayesian
Computation} (ABC) algorithms for performing parameter estimation, model
selection, and goodness-of-fit.  Cross-validation tools are also available for
measuring the accuracy of ABC estimates, and to calculate the
misclassification probabilities of different models.")
    (license license:gpl3+)))

(define-public r-zip
  (package
    (name "r-zip")
    (version "2.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "zip" version))
       (sha256
        (base32
         "1c02amk3pl6xir5jnbfiwiv2wvpkpbkkb1w71y6lf2yk7g3d0pdb"))))
    (build-system r-build-system)
    (home-page "https://github.com/gaborcsardi/zip")
    (synopsis "Cross-platform Zip compression")
    (description
     "This package provides a cross-platform Zip compression library for R.
It is a replacement for the @code{zip} function, that does not require any
additional external tools on any platform.")
    (license license:cc0)))

(define-public r-openxlsx
  (package
    (name "r-openxlsx")
    (version "4.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "openxlsx" version))
       (sha256
        (base32
         "1mwxldw9i9nfksx1i6h1kfs7vmsz9fgyllbsipar4vnfyqhqp8q7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-stringi" ,r-stringi)
       ("r-zip" ,r-zip)))
    (home-page "https://github.com/awalker89/openxlsx")
    (synopsis "Read, write and edit XLSX files")
    (description
     "This package simplifies the creation of Excel @code{.xlsx} files by
providing a high level interface to writing, styling and editing worksheets.
Through the use of Rcpp, read/write times are comparable to the @code{xlsx}
and @code{XLConnect} packages with the added benefit of removing the
dependency on Java.")
    (license license:gpl3)))

(define-public r-rio
  (package
    (name "r-rio")
    (version "0.5.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rio" version))
       (sha256
        (base32
         "0rfl56fdawlhc98451a9lcb6a6m56kw0i7dvd5hx58z025d8vsyk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-data-table" ,r-data-table)
       ("r-foreign" ,r-foreign)
       ("r-haven" ,r-haven)
       ("r-openxlsx" ,r-openxlsx)
       ("r-readxl" ,r-readxl)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/leeper/rio")
    (synopsis "Swiss-army knife for data I/O")
    (description
     "This package provides streamlined data import and export infrastructure
by making assumptions that the user is probably willing to make: @code{import}
and @code{export} determine the data structure from the file extension,
reasonable defaults are used for data import and export (e.g.,
@code{stringsAsFactors=FALSE}), web-based import is natively
supported (including from SSL/HTTPS), compressed files can be read directly
without explicit decompression, and fast import packages are used where
appropriate.  An additional convenience function, @code{convert}, provides a
simple method for converting between file types.")
    (license license:gpl2)))

(define-public r-maptools
  (package
    (name "r-maptools")
    (version "0.9-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "maptools" version))
       (sha256
        (base32
         "0v4llkxk8qs61vq4ykvaim4k23aagdaz0p62ns7zfq02sln3pfk9"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-foreign" ,r-foreign)
       ("r-lattice" ,r-lattice)
       ("r-sp" ,r-sp)))
    (home-page "https://r-forge.r-project.org/projects/maptools/")
    (synopsis "Tools for reading and handling spatial objects")
    (description
     "This package provides a set of tools for manipulating and reading
geographic data, in particular ESRI Shapefiles.  It includes binary access to
GSHHG shoreline files.  The package also provides interface wrappers for
exchanging spatial objects with other R packages.")
    ;; The C source files from shapelib are released under the Expat license.
    ;; The R code is released under GPL version 2 or later.
    (license (list license:gpl2+
                   license:expat))))

(define-public r-later
  (package
    (name "r-later")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "later" version))
       (sha256
        (base32
         "11xjavj7siz0xv2ffq1ld4bwl35jyrcfpvvs4p3ilpifxx49hyr7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)))
    (home-page "https://github.com/r-lib/later")
    (synopsis "Utilities for delaying function execution")
    (description
     "This package provides tools to execute arbitrary R or C functions some
time after the current time, after the R execution stack has emptied.")
    (license license:gpl2+)))

(define-public r-promises
  (package
    (name "r-promises")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "promises" version))
       (sha256
        (base32
         "01l0ydjvvy6afcg5d6pzvk1ikd3djq8n2flv8c831ksn68z0zsn8"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-later" ,r-later)
       ("r-magrittr" ,r-magrittr)
       ("r-r6" ,r-r6)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)))
    (home-page "https://rstudio.github.io/promises")
    (synopsis "Abstractions for promise-based asynchronous programming")
    (description
     "This package provides fundamental abstractions for doing asynchronous
programming in R using promises.  Asynchronous programming is useful for
allowing a single R process to orchestrate multiple tasks in the background
while also attending to something else.  Semantics are similar to JavaScript
promises, but with a syntax that is idiomatic R.")
    (license license:expat)))

(define-public r-dosnow
  (package
    (name "r-dosnow")
    (version "1.0.18")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "doSNOW" version))
       (sha256
        (base32
         "0rj72z5505cprh6wykhhiz08l9bmd966srqh2qypwivf321bvrvh"))))
    (properties `((upstream-name . "doSNOW")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-foreach" ,r-foreach)
       ("r-iterators" ,r-iterators)
       ("r-snow" ,r-snow)))
    (home-page "https://cran.r-project.org/web/packages/doSNOW")
    (synopsis "Foreach parallel adaptor for the snow package")
    (description
     "This package provides a parallel backend for the @code{%dopar%} function
using the @code{snow} package.")
    (license license:gpl2)))

(define-public r-snowfall
  (package
   (name "r-snowfall")
   (version "1.84-6.1")
   (source (origin
            (method url-fetch)
            (uri (cran-uri "snowfall" version))
            (sha256
             (base32 "13941rlw1jsdjsndp1plzj1cq5aqravizkrqn6l25r9im7rnsi2w"))))
   (build-system r-build-system)
   (propagated-inputs
    `(("r-snow" ,r-snow)))
   (home-page "https://cran.r-project.org/web/packages/snowfall/")
   (synopsis "Easier cluster computing")
   (description "This package is a usability wrapper around snow for easier
development of parallel R programs.  This package offers e.g. extended error
checks, and additional functions.  All functions work in sequential mode, too,
if no cluster is present or wished.  The package is also designed as connector
to the cluster management tool @code{sfCluster}, but can also used without
it.")
   (license license:gpl2+)))

(define-public r-rappdirs
  (package
    (name "r-rappdirs")
    (version "0.3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rappdirs" version))
       (sha256
        (base32
         "0ji6sg3bdn5gazkq14xmmcq7jnbsyxw4lzmmbgv6526j2vn93n1g"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rappdirs/")
    (synopsis "Determine where to save data, caches, and logs")
    (description
     "This package provides an easy way to determine which directories on the
user's computer should be used to save data, caches and logs.  It is a port of
Python's @url{https://github.com/ActiveState/appdirs,Appdirs} to R.")
    (license license:expat)))

(define-public r-renv
  (package
    (name "r-renv")
    (version "0.9.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "renv" version))
       (sha256
        (base32
         "02ayfgbpw4b58148dcxz31anaxncwczmxs1zzkskwj0rzhb2x60r"))))
    (properties `((upstream-name . "renv")))
    (build-system r-build-system)
    (home-page "https://rstudio.github.io/renv")
    (synopsis "Project environments")
    (description
     "This package provides a dependency management toolkit for R.  Using
renv, you can create and manage project-local R libraries, save the state of
these libraries to a lockfile, and later restore your library as required.
Together, these tools can help make your projects more isolated, portable, and
reproducible.")
    (license license:expat)))

(define-public r-learnr
  (package
    (name "r-learnr")
    (version "0.10.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "learnr" version))
       (sha256
        (base32
         "08xwmms6x58y3dsfbl9c6d03145hb4ij97nqr1cc9dxxilmr6x31"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-checkmate" ,r-checkmate)
       ("r-ellipsis" ,r-ellipsis)
       ("r-evaluate" ,r-evaluate)
       ("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-markdown" ,r-markdown)
       ("r-rappdirs" ,r-rappdirs)
       ("r-renv" ,r-renv)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-rprojroot" ,r-rprojroot)
       ("r-shiny" ,r-shiny)
       ("r-withr" ,r-withr)))
    (home-page "https://rstudio.github.io/learnr/")
    (synopsis "Interactive tutorials for R")
    (description
     "This package provides tools to create interactive tutorials using R
Markdown.  Use a combination of narrative, figures, videos, exercises, and
quizzes to create self-paced tutorials for learning about R and R packages.")
    (license license:asl2.0)))

(define-public r-analytics
  (package
    (name "r-analytics")
    (version "3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "analytics" version))
       (sha256
        (base32
         "0js3c8lwj3knccb55nq03cbjlf4w390p9aid2mi5x80l3ayd9in1"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-car" ,r-car)
       ("r-cluster" ,r-cluster)
       ("r-fractal" ,r-fractal)
       ("r-lmtest" ,r-lmtest)
       ("r-mass" ,r-mass)
       ("r-np" ,r-np)
       ("r-powerplus" ,r-powerplus)
       ("r-robust" ,r-robust)
       ("r-trend" ,r-trend)
       ("r-tsa" ,r-tsa)
       ("r-urca" ,r-urca)
       ("r-vim" ,r-vim)))
    (home-page "https://cran.r-project.org/web/packages/analytics/")
    (synopsis "Collection of data analysis tools")
    (description
     "This package is a collection of data analysis tools.  It includes tools
for regression outlier detection in a fitted linear model, stationary
bootstrap using a truncated geometric distribution, a comprehensive test for
weak stationarity, column means by group, weighted biplots, and a heuristic to
obtain a better initial configuration in non-metric MDS.")
    (license license:gpl2)))

(define-public r-reticulate
  (package
    (name "r-reticulate")
    (version "1.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "reticulate" version))
       (sha256
        (base32
         "0icb9zl9zlx75njv7y1dr450k0yw2n3q2jkr4nicnphdyfn69gkn"))))
    (build-system r-build-system)
    (inputs `(("python" ,python)))
    (propagated-inputs
     `(("r-rappdirs" ,r-rappdirs)
       ("r-jsonlite" ,r-jsonlite)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/rstudio/reticulate")
    (synopsis "R interface to Python")
    (description
     "This package provides an interface from R to Python modules, classes,
and functions.  When calling into Python, R data types are automatically
converted to their equivalent Python types.  When values are returned from
Python to R they are converted back to R types.")
    (license license:asl2.0)))

(define-public r-bibtex
  (package
    (name "r-bibtex")
    (version "0.4.2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bibtex" version))
       (sha256
        (base32
         "140hkjzdp3033cvji861rd06z1ixgpnn4n5amygqsmhnixk8ff07"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-stringr" ,r-stringr)))
    (home-page "https://github.com/romainfrancois/bibtex")
    (synopsis "Bibtex parser")
    (description "This package provides a utility for R to parse a bibtex
file.")
    (license license:gpl2+)))

(define-public r-ggseqlogo
  (package
    (name "r-ggseqlogo")
    (version "0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggseqlogo" version))
       (sha256
        (base32
         "13q6kcpxrqxqbji889fx63p0nsi08lk5yymkchig75r5k1d18ky1"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-ggplot2" ,r-ggplot2)))
    (home-page "https://github.com/omarwagih/ggseqlogo")
    (synopsis "ggplot2 extension for drawing genetic sequence logos")
    (description
     "The range of functions provided by this package makes it possible to
draw highly versatile genomic sequence logos.  Features include, but are not
limited to, modifying colour schemes and fonts used to draw the logo,
generating multiple logo plots, and aiding the visualisation with annotations.
Sequence logos can easily be combined with other ggplot2 plots.")
    ;; Unspecified version of the LGPL.
    (license license:lgpl3+)))

(define-public r-ggsci
  (package
    (name "r-ggsci")
    (version "2.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggsci" version))
       (sha256
        (base32
         "0g73x6grbka7ahjh6z23m3wrcifp5rdfdiasbl8lq4sp6rplxwaa"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-scales" ,r-scales)))
    (home-page "https://nanx.me/ggsci/")
    (synopsis "Scientific journal and sci-fi themed color palettes for ggplot2")
    (description
     "This package provides a collection of ggplot2 color palettes inspired by
plots in scientific journals, data visualization libraries, science fiction
movies, and TV shows.")
    (license license:gpl3)))

(define-public r-ggsignif
  (package
    (name "r-ggsignif")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggsignif" version))
       (sha256
        (base32
         "17j9hg967k1wp9xw3x84mqss58jkb8pvlrnlchz4i1hklgykxqbg"))))
    (build-system r-build-system)
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)))
    (home-page "https://github.com/const-ae/ggsignif")
    (synopsis "Significance brackets for ggplot2")
    (description
     "Enrich your ggplots with group-wise comparisons.  This package provides
an easy way to indicate if two groups are significantly different.  Commonly
this is shown by a bracket on top connecting the groups of interest which
itself is annotated with the level of significance.  The package provides a
single layer that takes the groups for comparison and the test as arguments
and adds the annotation to the plot.")
    (license license:gpl3)))

(define-public r-ggpubr
  (package
    (name "r-ggpubr")
    (version "0.2.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggpubr" version))
       (sha256
        (base32
         "0kb3hpmnhj4mkbx1kx0kv5y22himr8dijqx7ra0h8hi0pf2l2ha7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cowplot" ,r-cowplot)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-ggsci" ,r-ggsci)
       ("r-ggsignif" ,r-ggsignif)
       ("r-glue" ,r-glue)
       ("r-gridextra" ,r-gridextra)
       ("r-magrittr" ,r-magrittr)
       ("r-polynom" ,r-polynom)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-scales" ,r-scales)
       ("r-tidyr" ,r-tidyr)))
    (home-page "http://www.sthda.com/english/rpkgs/ggpubr")
    (synopsis "ggplot2-based publication-ready plots")
    (description
     "The ggplot2 package is an excellent and flexible package for elegant
data visualization in R.  However the default generated plots require some
formatting before we can send them for publication.  The ggpubr package
provides some easy-to-use functions for creating and customizing ggplot2-based
publication-ready plots.")
    (license license:gpl2)))

(define-public r-ellipse
  (package
    (name "r-ellipse")
    (version "0.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ellipse" version))
       (sha256
        (base32
         "0g82vc51m3c1k0hnpp2zla6amxxgk2mmkl8ssnsc49jv3599r6hs"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ellipse/")
    (synopsis "Functions for drawing ellipses and ellipse-like confidence regions")
    (description
     "This package contains various routines for drawing ellipses and
ellipse-like confidence regions, implementing the plots described in Murdoch
and Chow (1996), A graphical display of large correlation matrices, The
American Statistician 50, 178-180.  There are also routines implementing the
profile plots described in Bates and Watts (1988), Nonlinear Regression
Analysis and its Applications.")
    (license license:gpl2+)))

(define-public r-flashclust
  (package
    (name "r-flashclust")
    (version "1.01-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flashClust" version))
       (sha256
        (base32
         "0l4lpz451ll7f7lfxmb7ds24ppzhfg1c3ypvydglcc35p2dq99s8"))))
    (properties `((upstream-name . "flashClust")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/flashClust/")
    (synopsis "Implementation of optimal hierarchical clustering")
    (description
     "This package provides a fast implementation of hierarchical
clustering.")
    (license license:gpl2+)))

(define-public r-factominer
  (package
    (name "r-factominer")
    (version "2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "FactoMineR" version))
       (sha256
        (base32
         "0ldgf3daksh6lpblhqys67m4mxqx3q9s9n5plfam6dwshfik0ky6"))))
    (properties `((upstream-name . "FactoMineR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-car" ,r-car)
       ("r-cluster" ,r-cluster)
       ("r-ellipse" ,r-ellipse)
       ("r-flashclust" ,r-flashclust)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-lattice" ,r-lattice)
       ("r-leaps" ,r-leaps)
       ("r-mass" ,r-mass)
       ("r-scatterplot3d" ,r-scatterplot3d)))
    (home-page "http://factominer.free.fr")
    (synopsis "Multivariate exploratory data analysis and data mining")
    (description
     "This package provides exploratory data analysis methods to summarize,
visualize and describe datasets.  The main principal component methods are
available, those with the largest potential in terms of applications:
principal component analysis (PCA) when variables are quantitative,
correspondence analysis (CA) and multiple correspondence analysis (MCA) when
variables are categorical, Multiple Factor Analysis when variables are
structured in groups, etc. and hierarchical cluster analysis.")
    (license license:gpl2+)))

(define-public r-factoextra
  (package
    (name "r-factoextra")
    (version "1.0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "factoextra" version))
       (sha256
        (base32
         "0bpsbcmp6jpa9qk53dhfzghrz98dh0h0n68brl7rjz724yjbvhn8"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)
       ("r-cluster" ,r-cluster)
       ("r-dendextend" ,r-dendextend)
       ("r-factominer" ,r-factominer)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggpubr" ,r-ggpubr)
       ("r-ggrepel" ,r-ggrepel)
       ("r-reshape2" ,r-reshape2)
       ("r-tidyr" ,r-tidyr)))
    (home-page "http://www.sthda.com/english/rpkgs/factoextra")
    (synopsis "Extract and visualize the results of multivariate data analyses")
    (description
     "This package provides some easy-to-use functions to extract and
visualize the output of multivariate data analyses, including
@code{PCA} (Principal Component Analysis), @code{CA} (Correspondence
Analysis), @code{MCA} (Multiple Correspondence Analysis), @code{FAMD} (Factor
Analysis of Mixed Data), @code{MFA} (Multiple Factor Analysis) and
@code{HMFA} (Hierarchical Multiple Factor Analysis) functions from different R
packages.  It contains also functions for simplifying some clustering analysis
steps and provides ggplot2-based elegant data visualization.")
    (license license:gpl2)))

(define-public r-fansi
  (package
    (name "r-fansi")
    (version "0.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fansi" version))
       (sha256
        (base32
         "028ywjy538psnmdnddvy5jr3idzffr4hikzr4x97x0m30g4fws9w"))))
    (build-system r-build-system)
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://github.com/brodieG/fansi")
    (synopsis "ANSI control sequence aware string functions")
    (description
     "This package provides counterparts to R string manipulation functions
that account for the effects of ANSI text formatting control sequences.")
    (license license:gpl2+)))

(define-public r-nbclust
  (package
    (name "r-nbclust")
    (version "3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "NbClust" version))
       (sha256
        (base32
         "1vwb48zy6ln1ddpqmfngii1i80n8qmqyxnzdp6gbaq96lakl3w3c"))))
    (properties `((upstream-name . "NbClust")))
    (build-system r-build-system)
    (home-page "https://sites.google.com/site/malikacharrad/research/nbclust-package")
    (synopsis "Determine the best number of clusters in a data set")
    (description
     "NbClust provides 30 indexes for determining the optimal number of
clusters in a data set and offers the best clustering scheme from different
results to the user.")
    (license license:gpl2)))

(define-public r-hdf5r
  (package
    (name "r-hdf5r")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hdf5r" version))
       (sha256
        (base32
         "0c2p06k9bp9rf0fyavnxw5d8jr2bbgx3gjblahz581cpvsfksj9i"))))
    (build-system r-build-system)
    (inputs
     `(("hdf5" ,hdf5)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-bit64" ,r-bit64)
       ("r-r6" ,r-r6)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://hhoeflin.github.io/hdf5r")
    (synopsis "Interface to the HDF5 binary data format")
    (description
     "HDF5 is a data model, library and file format for storing and managing
large amounts of data.  This package provides a nearly feature complete,
object oriented wrapper for the HDF5 API using R6 classes.  Additionally,
functionality is added so that HDF5 objects behave very similar to their
corresponding R counterparts.")
    (license license:asl2.0)))

(define-public r-itertools
  (package
    (name "r-itertools")
    (version "0.1-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "itertools" version))
       (sha256
        (base32
         "1ls5biiva10pb1dj3ph4griykb9vam02hkrdmlr5a5wf660hg6xn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-iterators" ,r-iterators)))
    (home-page "https://cran.r-project.org/web/packages/itertools/")
    (synopsis "Iterator tools")
    (description
     "This package provides various tools for creating iterators, many
patterned after functions in the Python @code{itertools} module, and others
patterned after functions in the snow package.")
    (license license:gpl2)))

(define-public r-polynom
  (package
    (name "r-polynom")
    (version "1.4-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "polynom" version))
       (sha256
        (base32
         "1pflscwc0qzdf0y60j7s0dkglgmz18xajywfbn6s263idyr8idy5"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/polynom/")
    (synopsis "Functions for univariate polynomial manipulations")
    (description
     "This package provides a collection of functions to implement a class for
univariate polynomial manipulations.")
    (license license:gpl2)))

(define-public r-gbrd
  (package
    (name "r-gbrd")
    (version "0.4-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gbRd" version))
       (sha256
        (base32
         "06x97rw5i6v6cgjxkfhxnw4dn7lghn5q6ra7ri5ag1x9dkfzcl82"))))
    (properties `((upstream-name . "gbRd")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/gbRd/")
    (synopsis "Utilities for processing Rd objects and files")
    (description
     "This package provides utilities for processing Rd objects and files.
Extract argument descriptions and other parts of the help pages of
functions.")
    (license license:gpl2+)))

(define-public r-rjags
  (package
    (name "r-rjags")
    (version "4-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rjags" version))
       (sha256
        (base32
         "1nhaim84ww8fd6m8xlpmngqcnp2qpql29ahc38366fxja3ghngmx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-coda" ,r-coda)))
    (inputs
     `(("jags" ,jags)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "http://mcmc-jags.sourceforge.net")
    (synopsis "Bayesian graphical models using MCMC")
    (description
     "This package provides an R interface to the JAGS MCMC library.  JAGS is
Just Another Gibbs Sampler.  It is a program for analysis of Bayesian
hierarchical models using Markov Chain Monte Carlo (MCMC) simulation.")
    (license license:gpl2)))

(define-public r-rdpack
  (package
    (name "r-rdpack")
    (version "0.11-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rdpack" version))
       (sha256
        (base32
         "080y15p2hl4jsq91ak2f1y2kx1iqq5c5wzyx3zyhjwp01cahy0jq"))))
    (properties `((upstream-name . "Rdpack")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bibtex" ,r-bibtex)
       ("r-gbrd" ,r-gbrd)))
    (home-page "https://github.com/GeoBosh/Rdpack")
    (synopsis "Update and manipulate Rd documentation objects")
    (description
     "This package provides functions for manipulation of R documentation
objects, including functions @code{reprompt()} and @code{ereprompt()} for
updating Rd documentation for functions, methods and classes; it also includes
Rd macros for citations and import of references from bibtex files for use in
Rd files and roxygen2 comments, as well as many functions for manipulation of
references and Rd files.")
    (license license:gpl2+)))

(define-public r-officer
  (package
    (name "r-officer")
    (version "0.3.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "officer" version))
       (sha256
        (base32
         "0xhx5n6qksyh2s9hvwhnc8y0hn362asc5y94ld06snad786hz0rw"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-magrittr" ,r-magrittr)
       ("r-r6" ,r-r6)
       ("r-uuid" ,r-uuid)
       ("r-xml2" ,r-xml2)
       ("r-zip" ,r-zip)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://davidgohel.github.io/officer")
    (synopsis "Manipulation of Word and PowerPoint documents")
    (description
     "This package provides tools to access and manipulate Word and PowerPoint
documents from R.  The package focuses on tabular and graphical reporting from
R; it also provides two functions that let users get document content into
data objects.  A set of functions lets add and remove images, tables and
paragraphs of text in new or existing documents.  When working with PowerPoint
presentations, slides can be added or removed; shapes inside slides can also
be added or removed.  When working with Word documents, a cursor can be used
to help insert or delete content at a specific location in the document.")
    (license license:gpl3)))

(define-public r-abn
  (package
    (name "r-abn")
    (version "2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abn" version))
       (sha256
        (base32
         "19w6bdjyp4zwqs6p0flry4qxqynf9rh8ykdrfrp61wrdf7kysw0d"))))
    (build-system r-build-system)
    (inputs
     `(("gsl" ,gsl)))
    (propagated-inputs
     `(("r-lme4" ,r-lme4)
       ("r-mass" ,r-mass)
       ("r-nnet" ,r-nnet)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rjags" ,r-rjags)))
    (home-page "https://r-bayesian-networks.org/")
    (synopsis "Modelling multivariate data with additive bayesian networks")
    (description
     "Bayesian network analysis is a form of probabilistic graphical models
which derives from empirical data a directed acyclic graph, DAG, describing
the dependency structure between random variables.  An additive Bayesian
network model consists of a form of a DAG where each node comprises a
@dfn{generalized linear model} (GLM).  Additive Bayesian network models are
equivalent to Bayesian multivariate regression using graphical modelling, they
generalises the usual multivariable regression, GLM, to multiple dependent
variables.  This package provides routines to help determine optimal Bayesian
network models for a given data set, where these models are used to identify
statistical dependencies in messy, complex data.")
    (license license:gpl2+)))

(define-public r-acd
  (package
    (name "r-acd")
    (version "1.5.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACD" version))
       (sha256
        (base32
         "1a67bi3hklq8nlc50r0qnyr4k7m9kpvijy8sqqpm54by5hsysfd6"))))
    (properties `((upstream-name . "ACD")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ACD/")
    (synopsis "Categorical data analysis with complete or missing responses")
    (description
     "This package provides tools for categorical data analysis with complete
or missing responses.")
    (license license:gpl2+)))

(define-public r-acdm
  (package
    (name "r-acdm")
    (version "1.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACDm" version))
       (sha256
        (base32
         "0b4f02ga5ra66mbrm79g0bnlzmii82rks9kmxixxqgf18yhlyjil"))))
    (properties `((upstream-name . "ACDm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-plyr" ,r-plyr)
       ("r-rsolnp" ,r-rsolnp)
       ("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/ACDm/")
    (synopsis "Tools for Autoregressive Conditional Duration Models")
    (description
     "ACDm is a package for Autoregressive Conditional Duration (ACD, Engle
and Russell, 1998) models.  It creates trade, price or volume durations from
transactions (tic) data, performs diurnal adjustments, fits various ACD models
and tests them.")
    (license license:gpl2+)))

(define-public r-overlap
  (package
    (name "r-overlap")
    (version "0.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "overlap" version))
       (sha256
        (base32
         "1j3m6ir1chdz0si2fhcw6gs7c9h09bv0chz18rpzxsywww6d4rzy"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/overlap/")
    (synopsis "Estimates of coefficient of overlapping for animal activity patterns")
    (description
     "This package provides functions to fit kernel density functions to data
on temporal activity patterns of animals; estimate coefficients of overlapping
of densities for two species; and calculate bootstrap estimates of confidence
intervals.")
    (license license:gpl3+)))

(define-public r-snakecase
  (package
    (name "r-snakecase")
    (version "0.11.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "snakecase" version))
       (sha256
        (base32
         "1ky1x2cp5rd0ffd9m1fji9sq4z4jsrpxzg30brw8bb4ihfjj114r"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-stringi" ,r-stringi)
       ("r-stringr" ,r-stringr)))
    (home-page "https://github.com/Tazinho/snakecase")
    (synopsis "Convert strings into any case")
    (description
     "This package provides a consistent, flexible and easy to use tool to
parse and convert strings into cases like snake or camel among others.")
    (license license:gpl3)))

(define-public r-prediction
  (package
    (name "r-prediction")
    (version "0.3.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "prediction" version))
       (sha256
        (base32
         "0awlq5lxfia6m2b91w73rksp93rbwv5gwqb36wbji4rgq41rzbrx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)))
    (home-page "https://github.com/leeper/prediction")
    (synopsis "Tidy, type-safe prediction methods")
    (description
     "This package provides the @code{prediction()} function, a type-safe
alternative to @code{predict()} that always returns a data frame.  The package
currently supports common model types (e.g., @code{\"lm\"}, @code{\"glm\"})
from the @code{stats} package, as well as numerous other model classes from
other add-on packages.")
    (license license:expat)))

(define-public r-insight
  (package
    (name "r-insight")
    (version "0.8.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "insight" version))
       (sha256
        (base32
         "0fjf7dwpv1a7qfbzixppg348z1ksq19kdjm08vcb2am7w0k3plcj"))))
    (build-system r-build-system)
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://easystats.github.io/insight/")
    (synopsis "Easy access to model information for various model objects")
    (description
     "This package provides a tool to provide an easy, intuitive and
consistent access to information contained in various R models, like model
formulas, model terms, information about random effects, data that was used to
fit the model or data from response variables.  The package mainly revolves
around two types of functions: Functions that find (the names of) information,
starting with @code{find_}, and functions that get the underlying data,
starting with @code{get_}.  The package has a consistent syntax and works with
many different model objects, where otherwise functions to access these
information are missing.")
    (license license:gpl3)))

(define-public r-sjlabelled
  (package
    (name "r-sjlabelled")
    (version "1.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sjlabelled" version))
       (sha256
        (base32
         "1amq7i9sxf0pkxhskqc53xq5wvc9rdxm7cxyb4b6xh6qsskjnlsj"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-haven" ,r-haven)
       ("r-insight" ,r-insight)))
    (home-page "https://github.com/strengejacke/sjlabelled")
    (synopsis "Labelled data utility functions")
    (description
     "This package provides a collection of functions dealing with labelled
data, like reading and writing data between R and other statistical software
packages.  This includes easy ways to get, set or change value and variable
label attributes, to convert labelled vectors into factors or numeric (and
vice versa), or to deal with multiple declared missing values.")
    (license license:gpl3)))

(define-public r-sjmisc
  (package
    (name "r-sjmisc")
    (version "2.8.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sjmisc" version))
       (sha256
        (base32
         "0w8l9grmp4q775jrf4q6rxx36ld5daz9b0gdxyyh42xfihk6m62h"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-insight" ,r-insight)
       ("r-magrittr" ,r-magrittr)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-sjlabelled" ,r-sjlabelled)
       ("r-tidyselect" ,r-tidyselect)))
    (home-page "https://github.com/strengejacke/sjmisc")
    (synopsis "Data and variable transformation functions")
    (description
     "This package is a collection of miscellaneous utility functions,
supporting data transformation tasks like recoding, dichotomizing or grouping
variables, setting and replacing missing values.  The data transformation
functions also support labelled data, and all integrate seamlessly into a
tidyverse workflow.")
    (license license:gpl3)))

(define-public r-nortest
  (package
    (name "r-nortest")
    (version "1.0-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "nortest" version))
       (sha256
        (base32
         "17r0wpz72z9312c70nwi1i1kp1v9fm1h6jg7q5cx1mc1h420m1d3"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/nortest/")
    (synopsis "Tests for normality")
    (description
     "This package provides five omnibus tests for testing the composite
hypothesis of normality.")
    (license license:gpl2+)))

(define-public r-moonbook
  (package
    (name "r-moonbook")
    (version "0.2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "moonBook" version))
       (sha256
        (base32
         "0hys56mwbm776ff7dibi8wzyf69qiais9rs1jazv79lk6h56s9s6"))))
    (properties `((upstream-name . "moonBook")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-magrittr" ,r-magrittr)
       ("r-nortest" ,r-nortest)
       ("r-purrr" ,r-purrr)
       ("r-sjmisc" ,r-sjmisc)
       ("r-stringr" ,r-stringr)
       ("r-survival" ,r-survival)))
    (home-page "https://github.com/cardiomoon/moonBook")
    (synopsis "Functions and datasets for the book by Keon-Woong Moon")
    (description
     "This package provides several analysis-related functions for the book
entitled \"R statistics and graph for medical articles\" (written in Korean),
version 1, by Keon-Woong Moon with Korean demographic data with several plot
functions.")
    (license license:gpl2)))

(define-public r-flextable
  (package
    (name "r-flextable")
    (version "0.5.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flextable" version))
       (sha256
        (base32
         "1rkz0nhwjy1l8sb0kmna5v492n2ydnk7gydswnmf88r8vfyjczhw"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-data-table" ,r-data-table)
       ("r-gdtools" ,r-gdtools)
       ("r-htmltools" ,r-htmltools)
       ("r-knitr" ,r-knitr)
       ("r-officer" ,r-officer)
       ("r-rlang" ,r-rlang)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-xml2" ,r-xml2)))
    (home-page "https://davidgohel.github.io/flextable")
    (synopsis "Functions for tabular reporting")
    (description
     "This package provides tools to create pretty tables for HTML documents
and other formats.  Functions are provided to let users create tables, modify
and format their content.  It extends the @code{officer} package and can be
used within R markdown documents when rendering to HTML and to Word
documents.")
    (license license:gpl3)))

(define-public r-writexl
  (package
    (name "r-writexl")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "writexl" version))
       (sha256
        (base32
         "09fhdip6igcg97fjx4c7727cx2lb49l4d74l4i8rg2bag2s5lrj3"))))
    (build-system r-build-system)
    (inputs `(("zlib" ,zlib)))
    (home-page "https://github.com/ropensci/writexl")
    (synopsis "Export data frames to xlsx format")
    (description
     "This package provides a data frame to xlsx exporter based on
libxlsxwriter.")
    (license license:bsd-2)))

(define-public r-biasedurn
  (package
    (name "r-biasedurn")
    (version "1.07")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "BiasedUrn" version))
       (sha256
        (base32
         "13i2lgfnjhlbbm2yxfc2l5hswqw6x03pwba5csjmirv8kpjw4xr3"))))
    (properties `((upstream-name . "BiasedUrn")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/BiasedUrn/")
    (synopsis "Biased Urn model distributions")
    (description
     "This package provides statistical models of biased sampling in the form
of univariate and multivariate noncentral hypergeometric distributions,
including Wallenius' noncentral hypergeometric distribution and Fisher's
noncentral hypergeometric distribution (also called extended hypergeometric
distribution).")
    (license license:gpl3)))

(define-public r-goplot
  (package
    (name "r-goplot")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GOplot" version))
       (sha256
        (base32
         "1y8dv0kbzpr9za91njw0x233vx5d13vqml9hmpddcyi9s6va5nix"))))
    (properties `((upstream-name . "GOplot")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggdendro" ,r-ggdendro)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-rcolorbrewer" ,r-rcolorbrewer)))
    (home-page "https://github.com/wencke/wencke.github.io")
    (synopsis "Visualization of functional analysis data")
    (description
     "This package provides an implementation of multilayered visualizations
for enhanced graphical representation of functional analysis data.  It
combines and integrates omics data derived from expression and functional
annotation enrichment analyses.  Its plotting functions have been developed
with an hierarchical structure in mind: starting from a general overview to
identify the most enriched categories (modified bar plot, bubble plot) to a
more detailed one displaying different types of relevant information for the
molecules in a given set of categories (circle plot, chord plot, cluster plot,
Venn diagram, heatmap).")
    (license license:gpl2)))

(define-public r-getopt
  (package
    (name "r-getopt")
    (version "1.20.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "getopt" version))
       (sha256
        (base32
         "0zzmzgwl9a4y3s34600vmih22d6y32294f9bvxrnmffnvkgmy7sk"))))
    (build-system r-build-system)
    (home-page "https://github.com/trevorld/getopt")
    (synopsis "Command-line option processor for R")
    (description
     "This package is designed to be used with Rscript to write shebang
scripts that accept short and long options.  Many users will prefer to
use the packages @code{optparse} or @code{argparse} which add extra
features like automatically generated help options and usage texts,
support for default values, positional argument support, etc.")
    (license license:gpl2+)))

(define-public r-findpython
  (package
    (name "r-findpython")
    (version "1.0.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "findpython" version))
       (sha256
        (base32
         "0icifm4z6hhpmcjrg75a875iph0ci890ss02kdv3725pijc236iy"))))
    (build-system r-build-system)
    (home-page "https://github.com/trevorld/findpython")
    (synopsis "Functions to find an acceptable Python binary")
    (description
     "This package was designed to find an acceptable Python binary that
matches version and feature constraints.")
    (license license:expat)))

;; This in not the same as "r-argparser"
(define-public r-argparse
  (package
    (name "r-argparse")
    (version "2.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "argparse" version))
       (sha256
        (base32
         "1as7h6z7kzgv0fqzpnp76qbm96b4jcd37azd58b7rz0l1n94764l"))))
    (build-system r-build-system)
    (inputs `(("python" ,python)))
    (propagated-inputs
     `(("r-findpython" ,r-findpython)
       ("r-jsonlite" ,r-jsonlite)
       ("r-r6" ,r-r6)))
    (home-page "https://github.com/trevorld/argparse")
    (synopsis "Command line optional and positional argument parser")
    (description
     "This package provides a command line parser to be used with Rscript to
write shebang scripts that gracefully accept positional and optional arguments
and automatically generate usage notices.")
    (license license:gpl2+)))

(define-public r-hash
  (package
    (name "r-hash")
    (version "2.2.6.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hash" version))
       (sha256
        (base32
         "0b3fl0rvgwb992knl81vm99lsldg5clvaqjh6mamm6zqmb6dz056"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/hash/")
    (synopsis "Implementation of hash/associated arrays/dictionaries")
    (description
     "This package implements a data structure similar to hashes in Perl and
dictionaries in Python but with a purposefully R flavor.  For objects of
appreciable size, access using hashes outperforms native named lists and
vectors.")
    (license license:gpl2+)))

(define-public r-orddom
  (package
    (name "r-orddom")
    (version "3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "orddom" version))
       (sha256
        (base32
         "165axs15fvwhrp89xd87l81q3h2qjll1vrwcsap645cwvb85nwsh"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-psych" ,r-psych)))
    (home-page "https://cran.r-project.org/web/packages/orddom/")
    (synopsis "Ordinal dominance statistics")
    (description
     "This package provides tools to compute ordinal, statistics and effect
sizes as an alternative to mean comparison: Cliff's delta or success rate
difference (SRD), Vargha and Delaney's A or the Area Under a Receiver
Operating Characteristic Curve (AUC), the discrete type of McGraw & Wong's
Common Language Effect Size (CLES) or Grissom & Kim's Probability of
Superiority (PS), and the Number needed to treat (NNT) effect size.  Moreover,
comparisons to Cohen's d are offered based on Huberty & Lowman's Percentage of
Group (Non-)Overlap considerations.")
    (license license:gpl2)))

(define-public r-deriv
  (package
    (name "r-deriv")
    (version "4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Deriv" version))
       (sha256
        (base32
         "03mlfy8jzzzbh2l18gnmw0a71n9savx4cw72yhkxq93v2xj8fy3n"))))
    (properties `((upstream-name . "Deriv")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/Deriv")
    (synopsis "Symbolic differentiation")
    (description
     "This package provides an R-based solution for symbolic differentiation.
It admits user-defined functions as well as function substitution in arguments
of functions to be differentiated.  Some symbolic simplification is part of
the work.")
    (license license:gpl3+)))

(define-public r-doby
  (package
    (name "r-doby")
    (version "4.6.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "doBy" version))
       (sha256
        (base32
         "1ckazh701b4ilg8bj17ji903538jmb49d997gm49ah5j5jc1x0g7"))))
    (properties `((upstream-name . "doBy")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-broom" ,r-broom)
       ("r-deriv" ,r-deriv)
       ("r-dplyr" ,r-dplyr)
       ("r-magrittr" ,r-magrittr)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-plyr" ,r-plyr)
       ("r-pbkrtest" ,r-pbkrtest)
       ("r-tibble" ,r-tibble)))
    (home-page "http://people.math.aau.dk/~sorenh/software/doBy/")
    (synopsis "Groupwise statistics, LSmeans, linear contrasts, and utilities")
    (description
     "This package contains:

@itemize
@item facilities for working with grouped data: @code{do}
  something to data stratified @code{by} some variables.
@item implementations of least-squares means, general linear contrasts, and
@item miscellaneous other utilities.
@end itemize\n")
    (license license:gpl2+)))

(define-public r-refgenome
  (package
    (name "r-refgenome")
    (version "1.7.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "refGenome" version))
       (sha256
        (base32
         "1za89bn3am1zgvm641qi1ab6kaqpll4rb9p9f1sjwvcgqq6065g5"))))
    (properties `((upstream-name . "refGenome")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dbi" ,r-dbi)
       ("r-doby" ,r-doby)
       ("r-rsqlite" ,r-rsqlite)))
    (home-page "https://cran.r-project.org/web/packages/refGenome/")
    (synopsis
     "Gene and splice site annotation using annotation data from Ensembl and UCSC")
    (description
     "This package contains functionality for importing and managing of
downloaded genome annotation data from the Ensembl genome browser (European
Bioinformatics Institute) and from the UCSC genome browser (University of
California, Santa Cruz) and annotation routines for genomic positions and
splice site positions.")
    (license license:gpl2)))

(define-public r-basix
  (package
    (name "r-basix")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "BASIX" version))
       (sha256
        (base32
         "18dkvv1iwskfnlpl6xridcgqpalbbpm2616mvc3hfrc0b26v01id"))))
    (properties `((upstream-name . "BASIX")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/BASIX/")
    (synopsis "Efficient C/C++ toolset for R")
    (description
     "BASIX provides some efficient C/C++ implementations of native R
procedures to speed up calculations in R.")
    (license license:gpl2)))

(define-public r-blockfest
  (package
    (name "r-blockfest")
    (version "1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "BlockFeST" version))
       (sha256
        (base32
         "0hj7a5as7nxbgjac7lbj6qfwffx3g8x8phpf9a55f1c9cdzi73a5"))))
    (properties `((upstream-name . "BlockFeST")))
    (build-system r-build-system)
    (propagated-inputs `(("r-basix" ,r-basix)))
    (home-page "https://cran.r-project.org/web/packages/BlockFeST/")
    (synopsis "Bayesian calculation of region-specific fixation index")
    (description
     "This package provides an R implementation of an extension of the
BayeScan software for codominant markers, adding the option to group
individual SNPs into pre-defined blocks.  A typical application of this new
approach is the identification of genomic regions, genes, or gene sets
containing one or more SNPs that evolved under directional selection.")
    (license license:gpl2)))

(define-public r-proc
  (package
    (name "r-proc")
    (version "1.16.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pROC" version))
       (sha256
        (base32
         "0apwa5zzqh74pjnvf5a1s5qf6i9r5h44jdllfrwymkd2v479d2xn"))))
    (properties `((upstream-name . "pROC")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-plyr" ,r-plyr)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://web.expasy.org/pROC/")
    (synopsis "Display and analyze ROC curves")
    (description
     "This package provides tools for visualizing, smoothing and comparing
receiver operating characteristic (ROC curves).  The area under the
curve (AUC) can be compared with statistical tests based on U-statistics or
bootstrap.  Confidence intervals can be computed for (p)AUC or ROC curves.")
    (license license:gpl3+)))

(define-public r-rootsolve
  (package
    (name "r-rootsolve")
    (version "1.8.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rootSolve" version))
       (sha256
        (base32
         "0rj7c4zcrzgz7sb0vgvh7swpfafnw4040cxp7ypas3s8fnihn54l"))))
    (properties `((upstream-name . "rootSolve")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/rootSolve/")
    (synopsis "Tools for the analysis of ordinary differential equations")
    (description
     "This package provides routines to find the root of nonlinear functions,
and to perform steady-state and equilibrium analysis of @dfn{ordinary
differential equations} (ODE).  It includes routines that:

@enumerate
@item generate gradient and jacobian matrices (full and banded),
@item find roots of non-linear equations by the Newton-Raphson method,
@item estimate steady-state conditions of a system of (differential) equations
  in full, banded or sparse form, using the Newton-Raphson method, or by
  dynamically running,
@item solve the steady-state conditions for uni- and multicomponent 1-D, 2-D,
  and 3-D partial differential equations, that have been converted to ordinary
  differential equations by numerical differencing (using the method-of-lines
  approach).
@end enumerate\n")
    (license license:gpl2+)))

(define-public r-abcanalysis
  (package
    (name "r-abcanalysis")
    (version "1.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABCanalysis" version))
       (sha256
        (base32 "0wac1ksmnxa36v99ca4hv8k0rsh3igwpcllmlv9wf7i9kgqviqwi"))))
    (properties `((upstream-name . "ABCanalysis")))
    (build-system r-build-system)
    (propagated-inputs `(("r-plotrix" ,r-plotrix)))
    (home-page "https://www.uni-marburg.de/fb12/arbeitsgruppen/datenbionik/software-en/")
    (synopsis "Computed ABC Analysis")
    (description
     "Multivariate data sets often differ in several factors or derived statistical
parameters, which have to be selected for a valid interpretation.  Basing this
selection on traditional statistical limits leads occasionally to the perception
of losing information from a data set.  This package provides tools to calculate
these limits on the basis of the mathematical properties of the distribution of
the analyzed items.")
    (license license:gpl3)))

(define-public r-slam
  (package
    (name "r-slam")
    (version "0.1-47")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "slam" version))
       (sha256
        (base32 "12fggw2c7hz3bpvsaqm24g3r6lbpq6jgli24g7x5j859iak5cqv9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/slam/")
    (synopsis "Sparse lightweight arrays and matrices")
    (description
     "This package contains data structures and algorithms for sparse arrays and matrices,
based on index arrays and simple triplet representations, respectively.")
    (license license:gpl2)))

(define-public r-manipulatewidget
  (package
    (name "r-manipulatewidget")
    (version "0.10.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "manipulateWidget" version))
       (sha256
        (base32 "1vi71sjh7z1a880wffk8qqw7iysvk42q78giqxmm2sqz2a912qlx"))))
    (properties
     `((upstream-name . "manipulateWidget")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-codetools" ,r-codetools)
       ("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-knitr" ,r-knitr)
       ("r-miniui" ,r-miniui)
       ("r-shiny" ,r-shiny)
       ("r-webshot" ,r-webshot)))
    (home-page "https://github.com/rte-antares-rpackage/manipulateWidget/")
    (synopsis "Add even more interactivity to interactive charts")
    (description
     "This package lets you create in just a few lines of R code a nice user interface to
modify the data or the graphical parameters of one or multiple interactive
charts.  It is useful to quickly explore visually some data or for package
developers to generate user interfaces easy to maintain.")
    (license license:gpl2+)))

(define-public r-a3
  (package
    (name "r-a3")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "A3" version))
       (sha256
        (base32 "017hq9pjsv1h9i7cqk5cfx27as54shlhdsdvr6jkhb8jfkpdb6cw"))))
    (properties `((upstream-name . "A3")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-pbapply" ,r-pbapply)
       ("r-xtable" ,r-xtable)))
    (home-page "https://cran.r-project.org/web/packages/A3/")
    (synopsis "Error metrics for predictive models")
    (description
     "This package supplies tools for tabulating and analyzing the results of predictive
models.  The methods employed are applicable to virtually any predictive model
and make comparisons between different methodologies straightforward.")
    (license license:gpl2+)))

(define-public r-infotheo
  (package
    (name "r-infotheo")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "infotheo" version))
       (sha256
        (base32
         "18xacczfq3z3xpy434js4nf3l19lczngzd0lq26wh22pvg1yniwv"))))
    (build-system r-build-system)
    (home-page "http://homepage.meyerp.com/software")
    (synopsis "Information-theoretic measures")
    (description
     "This package implements various measures of information theory based on
several entropy estimators.")
    (license license:gpl3+)))

(define-public r-abcoptim
  (package
    (name "r-abcoptim")
    (version "0.15.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABCoptim" version))
       (sha256
        (base32 "1ih0xk88qhsmpvnxf56041wx5sk8as2f4f2gdnpnwdym9mbr9n4b"))))
    (properties `((upstream-name . "ABCoptim")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/gvegayon/ABCoptim/")
    (synopsis "Optimization of Artificial Bee Colony algorithm")
    (description
     "Artificial Bee Colony (ABC) is one of the most recently defined algorithms by Dervis
Karaboga in 2005, motivated by the intelligent behavior of honey bees.  It is as
simple as Particle Swarm Optimization (PSO) and Differential Evolution (DE)
algorithms, and uses only common control parameters such as colony size and
maximum cycle number.  The @code{r-abcoptim} implements the Artificial bee
colony optimization algorithm @url{http://mf.erciyes.edu.tr/abc/pub/tr06_2005.pdf}.
  This version is a work-in-progress and is written in R code.")
    (license license:expat)))

(define-public r-abcp2
  (package
    (name "r-abcp2")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABCp2" version))
       (sha256
        (base32 "1s2skkxpzss7c29i8600psgrp0hl46jcrxqrmy2b4db8hc0kcnbx"))))
    (properties `((upstream-name . "ABCp2")))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ABCp2/")
    (synopsis "Approximate Bayesian Computational Model for Estimating P2")
    (description
     "This package tests the goodness of fit of a distribution of offspring to the Normal,
Poisson, and Gamma distribution and estimates the proportional paternity of the
second male (P2) based on the best fit distribution.")
    (license license:gpl2)))

(define-public r-abcrf
  (package
    (name "r-abcrf")
    (version "1.8.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abcrf" version))
       (sha256
        (base32 "1ghbd24yhqy3xhdxas6ccn84nkavqpgldx5ck8kijknc7qjm8k27"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-doparallel" ,r-doparallel)
       ("r-foreach" ,r-foreach)
       ("r-mass" ,r-mass)
       ("r-matrixstats" ,r-matrixstats)
       ("r-ranger" ,r-ranger)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-readr" ,r-readr)
       ("r-stringr" ,r-stringr)))
    (home-page "https://cran.r-project.org/web/packages/abcrf/")
    (synopsis "Approximate bayesian computation via random forests")
    (description
     "This package performs approximate bayesian computation (ABC) model choice and
parameter inference via random forests.  This machine learning tool named random
forests (RF) can conduct selection among the highly complex models covered by
ABC algorithms.")
    (license license:gpl2+)))

(define-public r-abctools
  (package
    (name "r-abctools")
    (version "1.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abctools" version))
       (sha256
        (base32 "07s9dg10i8lsxl73b4n2hynca2fjgb0ykb0dz8c3zv6cgw3cyx97"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abc" ,r-abc)
       ("r-abind" ,r-abind)
       ("r-hmisc" ,r-hmisc)
       ("r-plyr" ,r-plyr)))
    (home-page "https://github.com/dennisprangle/abctools/")
    (synopsis "Tools for ABC analyses")
    (description
     "This @code{r-abctools} package provides tools for approximate Bayesian computation
including summary statistic selection and assessing coverage.  This includes
recent dimension reduction algorithms to tune the choice of summary statistics,
and coverage methods to tune the choice of threshold.")
    (license license:gpl2+)))

(define-public r-ggstance
  (package
    (name "r-ggstance")
    (version "0.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggstance" version))
       (sha256
        (base32 "0kdksay61hyb6612b07r84chh7a9aibjyclk3qcypvr9aang8hkh"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-plyr" ,r-plyr)
       ("r-rlang" ,r-rlang)
       ("r-withr" ,r-withr)))
    (home-page "https://cran.r-project.org/web/packages/ggstance/")
    (synopsis "Horizontal and vertical versions of @code{r-ggplot2}")
    (description
     "This package is a @code{r-ggplot2} extension that provides flipped components:
@enumerate
@item horizontal versions of @code{r-ggplot2} stats and @code{r-ggplot2} geoms;
@item vertical versions of @code{r-ggplot2} positions.
@end enumerate")
    (license license:gpl3)))

(define-public r-mosaiccore
  (package
    (name "r-mosaiccore")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mosaicCore" version))
       (sha256
        (base32 "1klw97h6lchw1cpcl8s637ikcl428cckmjq0czi7mibh9q9mw72z"))))
    (properties `((upstream-name . "mosaicCore")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-lazyeval" ,r-lazyeval)
       ("r-mass" ,r-mass)
       ("r-rlang" ,r-rlang)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/ProjectMOSAIC/mosaicCore/")
    (synopsis "Common utilities for mosaic family packages")
    (description
     "Common utilities used in other Mosaic family packages are collected here.")
    (license license:gpl2+)))

(define-public r-ggformula
  (package
    (name "r-ggformula")
    (version "0.9.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggformula" version))
       (sha256
        (base32 "04vdhg1bbc1psrx9ggaphz7cx4fw5xsmhkqpqfcg2w4ba2bjy46f"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggforce" ,r-ggforce)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggstance" ,r-ggstance)
       ("r-magrittr" ,r-magrittr)
       ("r-mosaiccore" ,r-mosaiccore)
       ("r-rlang" ,r-rlang)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/ProjectMOSAIC/ggformula/")
    (synopsis "Formula interface for the @code{r-ggplot2}")
    (description
     "The @code{r-ggformula} introduces a family of graphics functions, gf_point(),
gf_density(), and so on, bring the formula interface to ggplot().  This captures
and extends the excellent simplicity of the lattice-graphics formula interface,
while providing the intuitive capabilities of @code{r-ggplot2}.")
    (license license:expat)))

(define-public r-mosaicdata
  (package
    (name "r-mosaicdata")
    (version "0.17.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mosaicData" version))
       (sha256
        (base32 "04z0mdm52mykqsxsinhmsihn181zf6cw321gayk2rjp7lj7mwdq9"))))
    (properties `((upstream-name . "mosaicData")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/mosaicData/")
    (synopsis "Data sets for project Mosaic")
    (description
     "This package provides data sets from project Mosaic @url{http://mosaic-web.org}
used to teach mathematics, statistics, computation and modeling.")
    (license license:gpl2+)))

(define-public r-raster
  (package
    (name "r-raster")
    (version "3.0-12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "raster" version))
       (sha256
        (base32
         "0rrbsigkqxsdic8fly6nrsc79zsliwvr1x2b4xqpl9d34vr50dvg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-sp" ,r-sp)))
    (home-page "https://www.rspatial.org/")
    (synopsis "Geographic data analysis and modeling")
    (description
     "The package implements basic and high-level functions for reading,
writing, manipulating, analyzing and modeling of gridded spatial data.
Processing of very large files is supported.")
    (license license:gpl3+)))

(define-public r-mosaic
  (package
   (name "r-mosaic")
   (version "1.4.0")
   (source
    (origin
     (method url-fetch)
     (uri (cran-uri "mosaic" version))
     (sha256
      (base32 "10jbrg8kli00kfgbh2f67bymm5cnlancc9dplb1j7fl552yjddn2"))))
   (build-system r-build-system)
   (propagated-inputs
    `(("r-broom" ,r-broom)
      ("r-dplyr" ,r-dplyr)
      ("r-ggdendro" ,r-ggdendro)
      ("r-ggformula" ,r-ggformula)
      ("r-ggplot2" ,r-ggplot2)
      ("r-ggrepel" ,r-ggrepel)
      ("r-glue" ,r-glue)
      ("r-gridextra" ,r-gridextra)
      ("r-lattice" ,r-lattice)
      ("r-latticeextra" ,r-latticeextra)
      ("r-lazyeval" ,r-lazyeval)
      ("r-mass" ,r-mass)
      ("r-matrix" ,r-matrix)
      ("r-mosaiccore" ,r-mosaiccore)
      ("r-mosaicdata" ,r-mosaicdata)
      ("r-readr" ,r-readr)
      ("r-tidyr" ,r-tidyr)))
   (native-inputs
    `(("r-knitr" ,r-knitr)))
   (home-page "https://github.com/ProjectMOSAIC/mosaic/")
   (synopsis "Mathematics, statistics, and computation teaching utilities")
   (description
    "This package contain data sets and utilities from
@url{http://mosaic-web.org, Project MOSAIC} used to teach mathematics,
statistics, computation and modeling.  Project MOSAIC is a community of
educators working to tie together aspects of quantitative work that students
in science, technology, engineering and mathematics will need in their
professional lives, but which are usually taught in isolation, if at all.")
   (license license:gpl2+)))

(define-public r-abd
  (package
    (name "r-abd")
    (version "0.2-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abd" version))
       (sha256
        (base32 "191gspqzdv573vaw624ri0f5cm6v4j524bjs74d4a1hn3kn6r9b7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)
       ("r-mosaic" ,r-mosaic)
       ("r-nlme" ,r-nlme)))
    (home-page "https://cran.r-project.org/web/packages/abd/")
    (synopsis "Analysis of biological data")
    (description
     "The @code{r-abd} package contains data sets and sample code for the Analysis of
biological data by Michael Whitlock and Dolph Schluter.")
    (license license:gpl2)))

(define-public r-svgui
  (package
    (name "r-svgui")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "svGUI" version))
       (sha256
        (base32 "1r7ab0p4yr8q03gj02hmj7k1ghksgkg4nx750c0ajfs2q9y1dxfc"))))
    (properties `((upstream-name . "svGUI")))
    (build-system r-build-system)
    (home-page "https://github.com/SciViews/svGUI/")
    (synopsis "Functions for managing GUI clients in R")
    (description
     "The SciViews @code{svGUI} package eases the management of Graphical User
Interfaces (GUI) in R.  It is independent from any particular GUI widgets.  It
centralizes info about GUI elements currently used, and it dispatches GUI
calls to the particular toolkits in use in function of the context.")
    (license license:gpl2)))

(define-public r-svdialogs
  (package
    (name "r-svdialogs")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "svDialogs" version))
       (sha256
        (base32 "0xqppydfawnwk84kb5qiybwbcmv38vn4imgz01mz2pnq4xb80p97"))))
    (properties `((upstream-name . "svDialogs")))
    (build-system r-build-system)
    (inputs
     `(("yad" ,yad)
       ("zenity" ,zenity)))
    (propagated-inputs
     `(("r-rstudioapi" ,r-rstudioapi)
       ("r-svgui" ,r-svgui)))
    (home-page "https://github.com/SciViews/svDialogs/")
    (synopsis "Portable dialog boxes")
    (description
     "This package helps to construct standard dialog boxes for your GUI, including
message boxes, input boxes, list, file or directory selection, and others.  In
case R cannot display GUI dialog boxes, a simpler command line version of these
interactive elements is also provided as a fallback solution.")
    (license license:gpl2)))

(define-public r-abe
  (package
    (name "r-abe")
    (version "3.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abe" version))
       (sha256
        (base32
         "1f19h3xzzmjhvwc1rrb8z0rai3ip03y4gdi2gg9bfr5sg2nfklk6"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/abe/")
    (synopsis "Augmented backward elimination")
    (description
     "This package performs augmented backward elimination and checks the
stability of the obtained model.  Augmented backward elimination combines
significance or information based criteria with the change in estimate to
either select the optimal model for prediction purposes or to serve as a tool
to obtain a practically sound, highly interpretable model.")
    (license license:gpl2+)))

(define-public r-abf2
  (package
    (name "r-abf2")
    (version "0.7-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abf2" version))
       (sha256
        (base32 "0d65mc1w4pbiv7xaqzdlw1bfsxf25587rv597hh41vs0j0zlfpxx"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/abf2/")
    (synopsis "Load gap-free axon @code{r-abf2} files")
    (description
     "This package loads electrophysiology data from ABF2 files, as created by
Axon Instruments/Molecular Devices software.  Only files recorded in gap-free
mode are currently supported.")
    (license license:artistic2.0)))

(define-public r-abhgenotyper
  (package
    (name "r-abhgenotyper")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABHgenotypeR" version))
       (sha256
        (base32 "08cpmnaaxsm5c5bjifnfxdlvg5inrf13biqpcl2yq5zpqjmiki0l"))))
    (properties `((upstream-name . "ABHgenotypeR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-reshape2" ,r-reshape2)))
    (home-page "https://github.com/StefanReuscher/ABHgenotypeR/")
    (synopsis "Visualize and manipulate ABH genotypes")
    (description
     "The @code{r-abhgenotyper} package provides simple imputation,
error-correction and plotting capacities for genotype data.  The package is
supposed to serve as an intermediate but independent analysis tool between the
TASSEL GBS pipeline and the @code{r-qtl} package.  It provides functionalities
not found in either TASSEL or @code{r-qtl} in addition to visualization of
genotypes as \"graphical genotypes\".")
    (license license:gpl3)))

(define-public r-furrr
  (package
    (name "r-furrr")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "furrr" version))
       (sha256
        (base32
         "1ld9aa9hydna94hgm6p91zjbfv1dz1vsgchjlpknkg6irbvkfafx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-future" ,r-future)
       ("r-globals" ,r-globals)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)))
    (home-page "https://github.com/DavisVaughan/furrr")
    (synopsis "Apply mapping functions in parallel using futures")
    (description
     "This package provides implementations of the family of @code{map()}
functions from the @code{purrr} package that can be resolved using any
@code{future}-supported backend, e.g. parallel on the local machine or
distributed on a compute cluster.")
    (license license:lgpl2.1+)))

(define-public r-abjutils
  (package
    (name "r-abjutils")
    (version "0.2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abjutils" version))
       (sha256
        (base32 "0n4zps65y3zg0gfzlv97w91si52a9izkncirskbkj5x9hk0nhxcv"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-devtools" ,r-devtools)
       ("r-dplyr" ,r-dplyr)
       ("r-furrr" ,r-furrr)
       ("r-future" ,r-future)
       ("r-glue" ,r-glue)
       ("r-httr" ,r-httr)
       ("r-magrittr" ,r-magrittr)
       ("r-progress" ,r-progress)
       ("r-purrr" ,r-purrr)
       ("r-readr" ,r-readr)
       ("r-rlang" ,r-rlang)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-scales" ,r-scales)
       ("r-stringi" ,r-stringi)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/abjur/abjutils/")
    (synopsis "Collection of tools for jurimetrical analysis")
    (description
     "This package implements general purpose tools, such as functions for
sampling and basic manipulation of Brazilian lawsuits identification number.
It also implements functions for text cleaning, such as accentuation
removal.")
    (license license:expat)))

(define-public r-abnormality
  (package
    (name "r-abnormality")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abnormality" version))
       (sha256
        (base32 "1fzfskl9akl06nliy8hkv2a0pznpj8pwcypg3gj5r2nzvr3kan9v"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/abnormality/")
    (synopsis "Measure a subject's abnormality with respect to a reference population")
    (description
     "This package contains functions to implement the methodology and
considerations laid out by Marks et al. in the article \"Measuring abnormality
in high dimensional spaces: applications in biomechanical gait analysis\".
Using high-dimensional datasets to measure a subject's overall level of
abnormality as compared to a reference population is often needed in outcomes
research.")
    (license license:expat)))

(define-public r-abodoutlier
  (package
    (name "r-abodoutlier")
    (version "0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abodOutlier" version))
       (sha256
        (base32 "1pvhgxmh23br84r0fbmv7g53z2427birdja96a67vqgz18r3fdvj"))))
    (properties `((upstream-name . "abodOutlier")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cluster" ,r-cluster)))
    (home-page "https://cran.r-project.org/web/packages/abodOutlier/")
    (synopsis "Angle-based outlier detection")
    (description
     "This package performs angle-based outlier detection on a given data
frame.  It offers three methods to process data:
@enumerate
@item full but slow implementation using all the data that has cubic
  complexity;
@item a fully randomized method;
@item a method using k-nearest neighbours.
@end enumerate
These algorithms are well suited for high dimensional data outlier
detection.")
    (license license:expat)))

(define-public r-abps
  (package
    (name "r-abps")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABPS" version))
       (sha256
        (base32 "0n3f66nmfi5v94il1mxy026mi84w01ph2aljk60vn3mrz8kwf2ll"))))
    (properties `((upstream-name . "ABPS")))
    (build-system r-build-system)
    (propagated-inputs `(("r-kernlab" ,r-kernlab)))
    (home-page "https://cran.r-project.org/web/packages/ABPS/")
    (synopsis "Abnormal blood profile score to detect blood doping")
    (description
     "This package offers an implementation of the @dfn{Abnormal blood profile score} (ABPS).
The ABPS is a part of the Athlete biological passport program of the World
anti-doping agency, which combines several blood parameters into a single
score in order to detect blood doping.  The package also contains functions to
calculate other scores used in anti-doping programs, such as the ratio of
hemoglobin to reticulocytes (OFF-score), as well as example data.")
    (license license:gpl2+)))

(define-public r-parmigene
  (package
    (name "r-parmigene")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "parmigene" version))
       (sha256
        (base32
         "1fsm6pkr17jcbzkj1hbn91jf890fviqk1lq6ls8pihsdgah1zb4d"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/parmigene/")
    (synopsis "Mutual information estimation for gene network reconstruction")
    (description
     "This package provides a parallel estimation of the mutual information
based on entropy estimates from k-nearest neighbors distances and algorithms
for the reconstruction of gene regulatory networks.")
    (license license:agpl3+)))

(define-public r-pscl
  (package
    (name "r-pscl")
    (version "1.5.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pscl" version))
       (sha256
        (base32 "0vzf5wazs92bhqhqd66v3vwmbfmnh67gb2466g1xxawim649nk05"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://github.com/atahk/pscl/")
    (synopsis "Political science computational laboratory")
    (description
     "The @code{pscl} is an R package providing classes and methods for:
@enumerate
@item Bayesian analysis of roll call data (item-response models);
@item elementary Bayesian statistics;
@item maximum likelihood estimation of zero-inflated and hurdle models for count
data;
@item utility functions.
@end enumerate")
    (license license:gpl2)))

(define-public r-accelmissing
  (package
    (name "r-accelmissing")
    (version "1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accelmissing" version))
       (sha256
        (base32 "1nql9inx6azdzi3z4sfm2vdml2mms6krl8wzlf1dn1c97ahn57fy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mice" ,r-mice)
       ("r-pscl" ,r-pscl)))
    (home-page "https://cran.r-project.org/web/packages/accelmissing/")
    (synopsis "Missing value imputation for accelerometer data")
    (description
     "This package provides a statistical method to impute the missing values in
accelerometer data.  The methodology includes both parametric and
semi-parametric multiple imputations under the zero-inflated Poisson lognormal
model.  It also provides multiple functions to preprocess the accelerometer data
previous to the missing data imputation.  These include detecting the wearing
and the non-wearing time, selecting valid days and subjects, and creating plots.")
    (license license:gpl2+)))

(define-public r-mhsmm
  (package
    (name "r-mhsmm")
    (version "0.4.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mhsmm" version))
       (sha256
        (base32 "009dj0zkj1zry7jr9hf4cknb686z50a2l967if64xm0dvjmp7dgs"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://github.com/jaredo/mhsmm/")
    (synopsis "Inference for hidden Markov and semi-Markov models")
    (description
     "The @code{r-mhsmm} package implements estimation and prediction methods for
hidden Markov and semi-Markov models for multiple observation sequences.  Such
techniques are of interest when observed data is thought to be dependent on some
unobserved (or hidden) state.  Also, this package is suitable for equidistant
time series data, with multivariate and/or missing data.  Allows user defined
emission distributions.")
    (license license:gpl2+)))

(define-public r-nleqslv
  (package
    (name "r-nleqslv")
    (version "3.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "nleqslv" version))
       (sha256
        (base32 "1v9znvncyigw9r25wx2ma0b7ib179b488dl0qsrhp5zrcz7mcjgm"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/nleqslv/")
    (synopsis "Solve systems of nonlinear equations")
    (description
     "The @code{r-nleqslv} package solves a system of nonlinear equations using a
Broyden or a Newton method with a choice of global strategies such as line
search and trust region.  There are options for using a numerical or user
supplied Jacobian, for specifying a banded numerical Jacobian and for allowing a
singular or ill-conditioned Jacobian.")
    (license license:gpl2+)))

(define-public r-physicalactivity
  (package
    (name "r-physicalactivity")
    (version "0.2-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "PhysicalActivity" version))
       (sha256
        (base32 "14z6plgwyr46vs9m997rvlz8sdglfs9g087an8668zqkzzs2w4ln"))))
    (properties
     `((upstream-name . "PhysicalActivity")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/PhysicalActivity/")
    (synopsis "Procesing accelerometer data for physical activity measurement")
    (description
     "This @code{r-physicalactivity} package provides a function @code{wearingMarking}
for classification of monitor wear and nonwear time intervals in accelerometer
data collected to assess physical activity.  The package also contains functions
for making plots of accelerometer data and obtaining the summary of various
information including daily monitor wear time and the mean monitor wear time
during valid days.  The revised package version 0.2-1 improved the functions
regarding speed, robustness and add better support for time zones and daylight
saving.  In addition, several functions were added:
@enumerate
@item the @code{markDelivery} can classify days for ActiGraph delivery by mail;
@item the @code{markPAI} can categorize physical activity intensity level based
on user-defined cut-points of accelerometer counts.
@end enumerate
  It also supports importing ActiGraph (AGD) files with @code{readActigraph} and
@code{queryActigraph} functions.")
    (license license:gpl3+)))

(define-public r-acc
  (package
    (name "r-acc")
    (version "1.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acc" version))
       (sha256
        (base32 "1ii2vm47djxbixa75h690q1s2f9m9x6i8nkygik93j6dayr6kr1m"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-circlize" ,r-circlize)
       ("r-dbi" ,r-dbi)
       ("r-ggplot2" ,r-ggplot2)
       ("r-iterators" ,r-iterators)
       ("r-mhsmm" ,r-mhsmm)
       ("r-nleqslv" ,r-nleqslv)
       ("r-physicalactivity" ,r-physicalactivity)
       ("r-plyr" ,r-plyr)
       ("r-r-utils" ,r-r-utils)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rsqlite" ,r-rsqlite)
       ("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/acc/")
    (synopsis "Exploring accelerometer data")
    (description
     "This package processes accelerometer data from uni-axial and tri-axial devices
and generates data summaries.  Also, includes functions to plot, analyze, and
simulate accelerometer data.")
    (license license:gpl2+)))

(define-public r-rbenchmark
  (package
    (name "r-rbenchmark")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rbenchmark" version))
       (sha256
        (base32 "010fn3qwnk2k411cbqyvra1d12c3bhhl3spzm8kxffmirj4p2al9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rbenchmark/")
    (synopsis "Benchmarking routine for R")
    (description
     "This @code{r-rbenchmark} package is inspired by the Perl module Benchmark,
and is intended to facilitate benchmarking of arbitrary R code.  The library
consists of just one function, benchmark, which is a simple wrapper around
system.time.  Given a specification of the benchmarking process (counts of
replications, evaluation environment) and an arbitrary number of expressions,
benchmark evaluates each of the expressions in the specified environment,
replicating the evaluation as many times as specified, and returning the results
conveniently wrapped into a data frame.")
    (license license:gpl2+)))

(define-public r-mitools
  (package
    (name "r-mitools")
    (version "2.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mitools" version))
       (sha256
        (base32
         "0c2x2n1p53lcw0vx4vmy5j7m2f95i7g2iwbryl89imr99rvz617j"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-dbi" ,r-dbi)))
    (home-page "https://cran.r-project.org/web/packages/mitools/")
    (synopsis "Tools for multiple imputation of missing data")
    (description
     "This package provides tools to perform analyses and combine results from
multiple-imputation datasets.")
    (license license:gpl2)))

(define-public r-magick
  (package
    (name "r-magick")
    (version "2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "magick" version))
       (sha256
        (base32
         "182b4wahkq9q0scn99mql4vm9fp92nja0r5yizc4x9rjl492ahd8"))))
    (build-system r-build-system)
    (inputs
     `(("imagemagick" ,imagemagick)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-magrittr" ,r-magrittr)
       ("r-rcpp" ,r-rcpp)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/ropensci/magick")
    (synopsis "Advanced graphics and image-processing in R")
    (description
     "This package provides bindings to ImageMagick, a comprehensive image
processing library.  It supports many common formats (PNG, JPEG, TIFF, PDF,
etc.)  and manipulations (rotate, scale, crop, trim, flip, blur, etc).  All
operations are vectorized via the Magick++ STL meaning they operate either on
a single frame or a series of frames for working with layers, collages, or
animation.  In RStudio, images are automatically previewed when printed to the
console, resulting in an interactive editing environment.")
    (license license:expat)))

(define-public r-survey
  (package
    (name "r-survey")
    (version "3.37")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "survey" version))
       (sha256
        (base32
         "1f31dvh48gzzan13pdrwh84ls35x9116095i7mdrcbrhz809r8dy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)
       ("r-matrix" ,r-matrix)
       ("r-minqa" ,r-minqa)
       ("r-mitools" ,r-mitools)
       ("r-numderiv" ,r-numderiv)
       ("r-survival" ,r-survival)))
    (home-page "http://r-survey.r-forge.r-project.org/survey/")
    (synopsis "Analysis of complex survey samples")
    (description
     "This package provides tools for the analysis of complex survey samples.
The provided features include: summary statistics, two-sample tests, rank
tests, generalised linear models, cumulative link models, Cox models,
loglinear models, and general maximum pseudolikelihood estimation for
multistage stratified, cluster-sampled, unequally weighted survey samples;
variances by Taylor series linearisation or replicate weights;
post-stratification, calibration, and raking; two-phase subsampling designs;
graphics; PPS sampling without replacement; principal components, and factor
analysis.")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

(define-public r-gee
  (package
    (name "r-gee")
    (version "4.13-20")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gee" version))
       (sha256
        (base32
         "167pzgnmj4cjc41ykps1mfwi6s7y32zxyycn5z17vn4v0pp4q0ak"))))
    (properties `((upstream-name . "gee")))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/gee/")
    (synopsis "Generalized estimation equation solver")
    (description
     "This package provides a solver for generalized estimation equations.")
    (license license:gpl2)))

(define-public r-tab
  (package
    (name "r-tab")
    (version "4.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tab" version))
       (sha256
        (base32
         "0ds8n6gncidb66in7hlqkcmil5yfsf7ihqvmls789hrm2iz9xlfm"))))
    (properties `((upstream-name . "tab")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-gee" ,r-gee)
       ("r-knitr" ,r-knitr)
       ("r-mass" ,r-mass)
       ("r-survey" ,r-survey)
       ("r-survival" ,r-survival)
       ("r-xtable" ,r-xtable)))
    (home-page "https://cran.r-project.org/web/packages/tab/")
    (synopsis "Create summary tables for statistical reports")
    (description
     "This package contains functions for creating various types of summary
tables, e.g. comparing characteristics across levels of a categorical variable
and summarizing fitted generalized linear models, generalized estimating
equations, and Cox proportional hazards models.  Functions are available to
handle data from simple random samples as well as complex surveys.")
    (license license:gpl3+)))

(define-public r-dvmisc
  (package
    (name "r-dvmisc")
    (version "1.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dvmisc" version))
       (sha256
        (base32 "01v6sixx0f3nrn6ymfifb3pvd2msfrwm21kmdv38laxq29vc4rsi"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cubature" ,r-cubature)
       ("r-data-table" ,r-data-table)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-mass" ,r-mass)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-pracma" ,r-pracma)
       ("r-rbenchmark" ,r-rbenchmark)
       ("r-rcpp" ,r-rcpp)
       ("r-survey" ,r-survey)
       ("r-tab" ,r-tab)))
    (home-page "https://cran.r-project.org/web/packages/dvmisc/")
    (synopsis "Faster computation of common statistics and miscellaneous functions")
    (description
     "This package implements faster versions of base R functions (e.g. mean, standard
deviation, covariance, weighted mean), mostly written in C++, along with
miscellaneous functions for various purposes (e.g. create the histogram with
fitted probability density function or probability mass function curve, create
the body mass index groups, assess the linearity assumption in logistic
regression).")
    (license license:gpl2)))

(define-public r-accelerometry
  (package
    (name "r-accelerometry")
    (version "3.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accelerometry" version))
       (sha256
        (base32 "13xzrwhr4i1nj9c8vrmfdg2rmrc8n446iihcyxmy99sm99hpzyip"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dvmisc" ,r-dvmisc)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/accelerometry/")
    (synopsis "Functions for processing accelerometer data")
    (description
     "This package provides a collection of functions that perform operations on
time-series accelerometer data, such as identify the non-wear time, flag minutes
that are part of an activity bout, and find the maximum 10-minute average count
value.  The functions are generally very flexible, allowing for a variety of
algorithms to be implemented.")
    (license license:gpl3)))

(define-public r-absim
  (package
    (name "r-absim")
    (version "0.2.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AbSim" version))
       (sha256
        (base32 "16ddjk8b6xw80ch4jis1y751i9561wdxh0gifbf15qiz3vjckq8m"))))
    (properties `((upstream-name . "AbSim")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ape" ,r-ape)
       ("r-powerlaw" ,r-powerlaw)))
    (home-page "https://cran.r-project.org/web/packages/AbSim/")
    (synopsis "Time resolved simulations of antibody repertoires")
    (description
     "This package provides simulation methods for the evolution of antibody repertoires.
  The heavy and light chain variable region of both human and C57BL/6 mice can
be simulated in a time-dependent fashion.  Both single lineages using one set of
V-, D-, and J-genes or full repertoires can be simulated.  The algorithm begins
with an initial V-D-J recombination event, starting the first phylogenetic tree.
  Upon completion, the main loop of the algorithm begins, with each iteration
representing one simulated time step.  Various mutation events are possible at
each time step, contributing to a diverse final repertoire.")
    (license license:gpl2)))

(define-public r-quic
  (package
    (name "r-quic")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "QUIC" version))
       (sha256
        (base32 "021bp9xbaih60qmss015ycblbv6d1dvb1z89y93zpqqnc2qhpv3c"))))
    (properties `((upstream-name . "QUIC")))
    (build-system r-build-system)
    (home-page "https://www.cs.utexas.edu/users/sustik/QUIC/")
    (synopsis "Regularized sparse inverse covariance matrix estimation")
    (description
     "This package implements the regularized Gaussian maximum likelihood
estimation of the inverse of a covariance matrix.  It uses Newton's method and
coordinate descent to solve the regularized inverse covariance matrix
estimation problem.")
    ;; The project home page states that the release is under GPLv3 or later.
    ;; The CRAN page only says GPL-3.
    (license license:gpl3+)))

(define-public r-abundant
  (package
    (name "r-abundant")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abundant" version))
       (sha256
        (base32 "1m76qdmqvwpgm0sihazi2dna7cgsz9rljal18vgffb5wamwmg9k7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quic" ,r-quic)))
    (home-page "https://cran.r-project.org/web/packages/abundant/")
    (synopsis "Abundant regression and high-dimensional principal fitted components")
    (description
     "This package provides tools to fit and predict with the high-dimensional
principal fitted components model.  This model is described by Cook, Forzani,
and Rothman (2012) @url{doi:10.1214/11-AOS962}.")
    ;; The DESCRIPTION file states GPL-2, but since it directly depends on a
    ;; GPLv3+ package (QUIC) this likely means GPLv2+.
    (license license:gpl2+)))

(define-public r-ac3net
  (package
    (name "r-ac3net")
    (version "1.2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Ac3net" version))
       (sha256
        (base32 "1ns4n0xxz6p34c11bj0k7nzgmyqr9mis2b0g5nfz37dbikndyqyz"))))
    (properties `((upstream-name . "Ac3net")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)))
    (home-page "https://cran.r-project.org/web/packages/Ac3net/")
    (synopsis "Inferring directional conservative causal core gene networks")
    (description "This package infers directional Conservative causal core
(gene) networks (C3NET).  This is a version of the algorithm C3NET with
directional network.")
    (license license:gpl3+)))

(define-public r-aca
  (package
    (name "r-aca")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACA" version))
       (sha256
        (base32 "1i3hm27nvnkvc39xlh0d1blq8q0q02czmvgi3cazmjx3jvxay0vq"))))
    (properties `((upstream-name . "ACA")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ACA/")
    (synopsis "Abrupt change-point or aberration detection in point series")
    (description
     "This package offers an interactive function for the detection of breakpoints in
series.")
    ;; Any version of the GPL
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-acceptancesampling
  (package
    (name "r-acceptancesampling")
    (version "1.0-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AcceptanceSampling" version))
       (sha256
        (base32 "1z3rmln63ki2kik9kinbwr9qhr32ggbmh4mm3xqy6di119n47ca9"))))
    (properties
     `((upstream-name . "AcceptanceSampling")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/AcceptanceSampling/")
    (synopsis "Creation and evaluation of acceptance sampling plans")
    (description
     "This @code{r-acceptancesampling} provides functionality for creating and evaluating
acceptance sampling plans.  Acceptance sampling is a methodology commonly used
in quality control and improvement.  International standards of acceptance
sampling provide sampling plans for specific circumstances.  The aim of this
package is to provide an easy-to-use interface to visualize single, double or
multiple sampling plans.  In addition, methods have been provided to enable the
user to assess sampling plans against pre-specified levels of performance, as
measured by the probability of acceptance for a given level of quality in the
lot.")
    (license license:gpl3+)))

(define-public r-acclma
  (package
    (name "r-acclma")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACCLMA" version))
       (sha256
        (base32 "1na27sp18fq12gp6vxgqw1ffsz2yi1d8xvrxbrzx5g1kqxrayy0v"))))
    (properties `((upstream-name . "ACCLMA")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ACCLMA/")
    (synopsis "ACC & LMA graph plotting")
    (description
     "This package contains a function that imports data from a @acronym{CSV,
Comma-Separated Values} file, or uses manually entered data from the format (x,
y, weight) and plots the appropriate @acronym{ACC, Absolute Concentration
Curve} vs @acronym{LOI, Line of Independence} graph and
@acronym{LMA, @acronym{LOI} Minus @acronym{ACC}} graph.  The main
function is @code{plotLMA} (source file, header) that takes a data set and plots the
appropriate @acronym{LMA} and @acronym{ACC} graphs.  If no source file (a
string) was passed, a manual data entry window is opened.  The header parameter
indicates by TRUE/FALSE (false by default) if the source @acronym{CSV} file has
a header row or not.  The dataset should contain only one independent variable
(x) and one dependent variable (y) and can contain a weight for each
observation.")
    (license license:gpl2)))

(define-public r-aspi
  (package
    (name "r-aspi")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "aspi" version))
       (sha256
        (base32 "0rhvxw243vvdv3hxa6pi343gcjc2cbxq1jzqirl9k1l4i3897l87"))))
    (build-system r-build-system)
    (home-page
     "https://cran.r-project.org/web/packages/aspi/")
    (synopsis
     "Analysis of symmetry of parasitic infections")
    (description
     "This package provides tools for the analysis and visualization of bilateral
      asymmetry in parasitic infections.")
    (license license:gpl3+)))

(define-public r-sandwich
  (package
    (name "r-sandwich")
    (version "2.5-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sandwich" version))
       (sha256
        (base32
         "1mk685b9wq7k566pbml52rj96i5h6b3vf215k9picgmq296nzvyv"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/sandwich/")
    (synopsis "Robust Covariance Matrix Estimators")
    (description
     "This package provides model-robust standard error estimators for
cross-sectional, time series, clustered, panel, and longitudinal data.")
    ;; Either version of the license.
    (license (list license:gpl2 license:gpl3))))

(define-public r-th-data
  (package
    (name "r-th-data")
    (version "1.0-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TH.data" version))
       (sha256
        (base32
         "0mgz7aj2d9abbmdr65zgmg1ddp3fdbs3mfj83r5xadh5ldkir2k1"))))
    (properties `((upstream-name . "TH.data")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/TH.data/")
    (synopsis "Shared data sets")
    (description
     "This package contains supporting data sets that are used in other
packages maintained by Torsten Hothorn.")
    (license license:gpl3)))

(define-public r-multcomp
  (package
    (name "r-multcomp")
    (version "1.4-12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "multcomp" version))
       (sha256
        (base32
         "14c2f10rz546w7ly5f4r6wnd07yj5gic38an17gxny1vf2nsff0b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-codetools" ,r-codetools)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-sandwich" ,r-sandwich)
       ("r-survival" ,r-survival)
       ("r-th-data" ,r-th-data)))
    (home-page "https://cran.r-project.org/web/packages/multcomp/")
    (synopsis "Simultaneous inference in general parametric models")
    (description
     "Simultaneous tests and confidence intervals for general linear
hypotheses in parametric models, including linear, generalized linear, linear
mixed effects, and survival models.  The package includes demos reproducing
analyzes presented in the book \"Multiple Comparisons Using R\" (Bretz,
Hothorn, Westfall, 2010, CRC Press).")
    (license license:gpl2)))

(define-public r-emmeans
  (package
    (name "r-emmeans")
    (version "1.4.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "emmeans" version))
       (sha256
        (base32
         "10fmvmd6q4zjr6b18hhc85mwrzv778qzj6lwl9kbs2fsfvsgw7mm"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-estimability" ,r-estimability)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-numderiv" ,r-numderiv)
       ("r-plyr" ,r-plyr)
       ("r-xtable" ,r-xtable)))
    (home-page "https://github.com/rvlenth/emmeans")
    (synopsis "Estimated marginal means, aka least-squares means")
    (description
     "This package provides tools to obtain @dfn{estimated marginal
means} (EMMs) for many linear, generalized linear, and mixed models.  It can
be used to compute contrasts or linear functions of EMMs, trends, and
comparisons of slopes.")
    ;; Either version of the license.
    (license (list license:gpl2 license:gpl3))))

(define-public r-pwr
  (package
    (name "r-pwr")
    (version "1.3-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pwr" version))
       (sha256
        (base32
         "1kfzy73v3z6ipc3kdfkcjrp4b4p5k54nwk796gqi36srm93hgc2v"))))
    (build-system r-build-system)
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/heliosdrm/pwr")
    (synopsis "Basic functions for power analysis")
    (description
     "This package provides power analysis functions along the lines of
Cohen (1988).")
    (license license:gpl3+)))

(define-public r-libcoin
  (package
    (name "r-libcoin")
    (version "1.0-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "libcoin" version))
       (sha256
        (base32
         "1cm9x1dlg9f7fh7n5nw3x4a7rl88c7ylrlc8x3rx4mq5w1j42x0a"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://cran.r-project.org/web/packages/libcoin")
    (synopsis "Linear test statistics for permutation inference")
    (description
     "This package provides basic infrastructure for linear test statistics
and permutation inference in the framework of Strasser and Weber (1999).")
    (license license:gpl2)))

(define-public r-coin
  (package
    (name "r-coin")
    (version "1.3-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "coin" version))
       (sha256
        (base32
         "0qi03fyqw42a2vnqcia5l2m1mzyarj2q1iblknx9n19bdsd53qjx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-libcoin" ,r-libcoin)
       ("r-matrixstats" ,r-matrixstats)
       ("r-modeltools" ,r-modeltools)
       ("r-multcomp" ,r-multcomp)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-survival" ,r-survival)))
    (home-page "http://coin.r-forge.r-project.org")
    (synopsis "Conditional inference procedures in a permutation test framework")
    (description
     "This package provides conditional inference procedures for the general
independence problem including two-sample, K-sample (non-parametric ANOVA),
correlation, censored, ordered and multivariate problems.")
    (license license:gpl2)))

(define-public r-bayesplot
  (package
    (name "r-bayesplot")
    (version "1.7.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bayesplot" version))
       (sha256
        (base32
         "0sq0ajnm96hmlqf1cv5n2gshh3qdij4n1zbm7qrniz2q6b5aj342"))))
    (build-system r-build-system)
    (inputs
     `(("pandoc" ,ghc-pandoc)
       ("pandoc-citeproc" ,ghc-pandoc-citeproc)))
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggridges" ,r-ggridges)
       ("r-glue" ,r-glue)
       ("r-reshape2" ,r-reshape2)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)
       ("r-tidyselect" ,r-tidyselect)))
    (home-page "https://mc-stan.org/bayesplot")
    (synopsis "Plotting for Bayesian models")
    (description
     "This package provides plotting functions for posterior analysis, model
checking, and MCMC diagnostics.  The package is designed not only to provide
convenient functionality for users, but also a common set of functions that
can be easily used by developers working on a variety of R packages for
Bayesian modeling.")
    (license license:gpl3+)))

(define-public r-tmb
  (package
    (name "r-tmb")
    (version "1.7.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TMB" version))
       (sha256
        (base32
         "0lly12hdi99iklwr0vg9xkyhi038w4gncbf895qcwbndmqp0lx44"))))
    (properties `((upstream-name . "TMB")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "http://tmb-project.org")
    (synopsis "Template model builder: a general random effect tool")
    (description
     "With this tool, a user should be able to quickly implement complex
random effect models through simple C++ templates.  The package combines
@code{CppAD} (C++ automatic differentiation), @code{Eigen} (templated
matrix-vector library) and @code{CHOLMOD} (sparse matrix routines available
from R) to obtain an efficient implementation of the applied Laplace
approximation with exact derivatives.  Key features are: Automatic sparseness
detection, parallelism through BLAS and parallel user templates.")
    (license license:gpl2)))

(define-public r-sjstats
  (package
    (name "r-sjstats")
    (version "0.17.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sjstats" version))
       (sha256
        (base32 "0938ac6ixvkif07azd2msa8g3qnn9rabj6jg17almbysl83kg4nm"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayestestr" ,r-bayestestr)
       ("r-broom" ,r-broom)
       ("r-dplyr" ,r-dplyr)
       ("r-effectsize" ,r-effectsize)
       ("r-emmeans" ,r-emmeans)
       ("r-insight" ,r-insight)
       ("r-lme4" ,r-lme4)
       ("r-magrittr" ,r-magrittr)
       ("r-mass" ,r-mass)
       ("r-modelr" ,r-modelr)
       ("r-parameters" ,r-parameters)
       ("r-performance" ,r-performance)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-sjlabelled" ,r-sjlabelled)
       ("r-sjmisc" ,r-sjmisc)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/strengejacke/sjstats")
    (synopsis "Functions for common statistical computations")
    (description
     "This package provides a collection of convenient functions for common
statistical computations, which are not directly provided by R's @code{base}
or @code{stats} packages.  This package aims at providing, first, shortcuts
for statistical measures, which otherwise could only be calculated with
additional effort.  Second, these shortcut functions are generic, and can be
applied not only to vectors, but also to other objects as well.  The focus of
most functions lies on summary statistics or fit measures for regression
models, including generalized linear models, mixed effects models and Bayesian
models.")
    (license license:gpl3)))

(define-public r-glmmtmb
  (package
    (name "r-glmmtmb")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "glmmTMB" version))
       (sha256
        (base32
         "0sdx1q7wc7895xh8747r4p0wkij0xjgn5ij62ipi9423zd0sr0mm"))))
    (properties `((upstream-name . "glmmTMB")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lme4" ,r-lme4)
       ("r-matrix" ,r-matrix)
       ("r-nlme" ,r-nlme)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-tmb" ,r-tmb)))
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://github.com/glmmTMB")
    (synopsis "Generalized linear mixed models")
    (description
     "Fit linear and generalized linear mixed models with various extensions,
including zero-inflation.  The models are fitted using maximum likelihood
estimation via the Template Model Builder.  Random effects are assumed to be
Gaussian on the scale of the linear predictor and are integrated out using the
Laplace approximation.  Gradients are calculated using automatic
differentiation.")
    (license license:agpl3+)))

(define-public r-bayestestr
  (package
    (name "r-bayestestr")
    (version "0.5.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bayestestR" version))
       (sha256
        (base32
         "1q24qh5p6bz4nbf4546kckh7d518x5pm1yhhbc8fwcnbca4kgqjz"))))
    (properties `((upstream-name . "bayestestR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-insight" ,r-insight)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/easystats/bayestestR")
    (synopsis "Describe Bayesian models and posterior distributions")
    (description
     "This package provides utilities to understand and describe posterior
distributions and Bayesian models.  It includes point-estimates such as
@dfn{Maximum A Posteriori} (MAP), measures of dispersion such as @dfn{Highest
Density Interval} (HDI), and indices used for null-hypothesis testing (such as
ROPE percentage and pd).")
    (license license:gpl3)))

(define-public r-performance
  (package
    (name "r-performance")
    (version "0.4.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "performance" version))
       (sha256
        (base32
         "18h9y66cpsb3k6xnaya87vnpv2s3chf4bzsc4ym3n5sxhh41j7la"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayestestr" ,r-bayestestr)
       ("r-insight" ,r-insight)))
    (home-page "https://easystats.github.io/performance/")
    (synopsis "Assessment of regression models performance")
    (description
     "This package provides utilities for computing measures to assess model
quality, which are not directly provided by R's @code{base} or @code{stats}
packages.  These include e.g. measures like r-squared, intraclass correlation
coefficient, root mean squared error or functions to check models for
overdispersion, singularity or zero-inflation and more.  Functions apply to a
large variety of regression models, including generalized linear models, mixed
effects models and Bayesian models.")
    (license license:gpl3)))

(define-public r-ggeffects
  (package
    (name "r-ggeffects")
    (version "0.14.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggeffects" version))
       (sha256
        (base32
         "1y3yfb07jrr6vkc8hk6rp52l70dj7042jvqgjzllslzy7hx2jhyw"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-insight" ,r-insight)
       ("r-mass" ,r-mass)
       ("r-sjlabelled" ,r-sjlabelled)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/strengejacke/ggeffects")
    (synopsis "Create tidy data frames of marginal effects for ggplot")
    (description
     "This package provides tools to compute marginal effects from statistical
models and return the result as tidy data frames.  These data frames are ready
to use with the @code{ggplot2} package.  Marginal effects can be calculated
for many different models.  Interaction terms, splines and polynomial terms
are also supported.  The two main functions are @code{ggpredict()} and
@code{ggeffect()}.  There is a generic @code{plot()} method to plot the
results using @code{ggplot2}.")
    (license license:gpl3)))

(define-public r-effectsize
  (package
    (name "r-effectsize")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "effectsize" version))
       (sha256
        (base32
         "1liix8rf8xq3hzi7684bl0s20iflsq6g5mxr5k59wp2qwn1i6aww"))))
    (properties `((upstream-name . "effectsize")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayestestr" ,r-bayestestr)
       ("r-insight" ,r-insight)
       ("r-parameters" ,r-parameters)))
    (home-page "https://github.com/easystats/effectsize")
    (synopsis "Indices of effect size and standardized parameters")
    (description
     "This package provides utilities to work with indices of effect size and
standardized parameters for a wide variety of models, allowing computation and
conversion of indices such as Cohen's d, r, odds, etc.")
    (license license:gpl3)))

(define-public r-sjplot
  (package
    (name "r-sjplot")
    (version "2.8.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sjPlot" version))
       (sha256
        (base32 "0ip1rkjlhyf3axlc8qqss1qq1f0xrda890c1jmcbhm98wwjw264f"))))
    (properties `((upstream-name . "sjPlot")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayestestr" ,r-bayestestr)
       ("r-dplyr" ,r-dplyr)
       ("r-effectsize" ,r-effectsize)
       ("r-ggeffects" ,r-ggeffects)
       ("r-ggplot2" ,r-ggplot2)
       ("r-insight" ,r-insight)
       ("r-knitr" ,r-knitr)
       ("r-mass" ,r-mass)
       ("r-parameters" ,r-parameters)
       ("r-performance" ,r-performance)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-scales" ,r-scales)
       ("r-sjlabelled" ,r-sjlabelled)
       ("r-sjmisc" ,r-sjmisc)
       ("r-sjstats" ,r-sjstats)
       ("r-tidyr" ,r-tidyr)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://strengejacke.github.io/sjPlot/")
    (synopsis "Data visualization for statistics in social science")
    (description
     "This package represents a collection of plotting and table output
functions for data visualization.  Results of various statistical
analyses (that are commonly used in social sciences) can be visualized using
this package, including simple and cross tabulated frequencies, histograms,
box plots, (generalized) linear models, mixed effects models, principal
component analysis and correlation matrices, cluster analyses, scatter plots,
stacked scales, effects plots of regression models (including interaction
terms) and much more.  This package supports labelled data.")
    (license license:gpl3)))

(define-public r-ini
  (package
    (name "r-ini")
    (version "0.3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ini" version))
       (sha256
        (base32
         "04yqij344dwm0xqgara8xia42mlmij3i8711qbb5534w05a1l6bv"))))
    (build-system r-build-system)
    (home-page "https://github.com/dvdscripter/ini")
    (synopsis "Read and write configuration files")
    (description
     "This package provides tools to parse simple @code{.ini} configuration
files to an structured list.  Users can manipulate this resulting list with
@code{lapply()} functions.  This same structured list can be used to write
back to file after modifications.")
    (license license:gpl3)))

(define-public r-gh
  (package
    (name "r-gh")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gh" version))
       (sha256
        (base32
         "1bc9bn1078s664hc806dh0y1ncxif77q479rfmxfir9z7hwaz7yy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cli" ,r-cli)
       ("r-httr" ,r-httr)
       ("r-ini" ,r-ini)
       ("r-jsonlite" ,r-jsonlite)))
    (home-page "https://github.com/r-lib/gh#readme")
    (synopsis "Access the GitHub API via R")
    (description
     "This package provides a minimal R client to access the GitHub API.")
    (license license:expat)))

(define-public r-fs
  (package
    (name "r-fs")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fs" version))
       (sha256
        (base32
         "1w30bflx4d7a6f3dn96bf7s7v6aqpvz2yzzxal6qz9jyhb16bxaz"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://fs.r-lib.org")
    (synopsis "Cross-platform file system operations based on libuv")
    (description
     "This package provides a cross-platform interface to file system
operations, built on top of the libuv C library.")
    (license license:gpl3)))

(define-public r-clisymbols
  (package
    (name "r-clisymbols")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "clisymbols" version))
       (sha256
        (base32
         "1q7gi2zmykhzas9v8fdnbpdq7pzdcpbhim1yxvd2062l777g4j86"))))
    (build-system r-build-system)
    (home-page "https://github.com/gaborcsardi/clisymbols")
    (synopsis "Unicode symbols at the R prompt")
    (description
     "This package provides a small subset of Unicode symbols, that are useful
when building command line applications.  They fall back to alternatives on
terminals that do not support Unicode.")
    (license license:expat)))

(define-public r-usethis
  (package
    (name "r-usethis")
    (version "1.5.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "usethis" version))
       (sha256
        (base32
         "07an5wbikilg7cb3q6x5aykw8dfqnjrc3wpfb7gjmy0d9fh20fcy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-clipr" ,r-clipr)
       ("r-clisymbols" ,r-clisymbols)
       ("r-crayon" ,r-crayon)
       ("r-curl" ,r-curl)
       ("r-desc" ,r-desc)
       ("r-fs" ,r-fs)
       ("r-gh" ,r-gh)
       ("r-git2r" ,r-git2r)
       ("r-glue" ,r-glue)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-rprojroot" ,r-rprojroot)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-whisker" ,r-whisker)
       ("r-withr" ,r-withr)
       ("r-yaml" ,r-yaml)))
    (home-page "https://github.com/r-lib/usethis")
    (synopsis "Automate R package and project setup")
    (description
     "This package helps you to automate R package and project setup tasks
that are otherwise performed manually.  This includes setting up unit testing,
test coverage, continuous integration, Git, GitHub integration, licenses,
Rcpp, RStudio projects, and more.")
    (license license:gpl3)))

(define-public r-sessioninfo
  (package
    (name "r-sessioninfo")
    (version "1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sessioninfo" version))
       (sha256
        (base32
         "0j5f3l58fynxx3v0w62vqpii7miabszgljpja36xx9s8hikh8sqn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cli" ,r-cli)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/r-lib/sessioninfo#readme")
    (synopsis "R session information")
    (description
     "This package provides tools to query and print information about the
current R session.  It is similar to @code{utils::sessionInfo()}, but includes
more information about packages, and where they were installed from.")
    (license license:gpl2)))

(define-public r-remotes
  (package
    (name "r-remotes")
    (version "2.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "remotes" version))
       (sha256
        (base32
         "12qinl7jv54f2524ri13gcrv6d523rg1harpi500j676zi30fnaf"))))
    (build-system r-build-system)
    (home-page "https://github.com/r-lib/remotes#readme")
    (synopsis "R package installation from remote repositories")
    (description
     "Download and install R packages stored in GitHub, BitBucket, or plain
subversion or git repositories.  This package is a lightweight replacement of
the @code{install_*} functions in the @code{devtools} package.  Indeed most of
the code was copied over from @code{devtools}.")
    (license license:gpl2+)))

(define-public r-xopen
  (package
    (name "r-xopen")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xopen" version))
       (sha256
        (base32
         "1vrvgdika1d63dwygynbv2wmd87ll8dji5dy89hj576n8hw601z2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-processx" ,r-processx)))
    (home-page "https://github.com/r-lib/xopen#readme")
    (synopsis "Open system files, URLs, anything")
    (description
     "This package provides a cross-platform solution to open files,
directories or URLs with their associated programs.")
    (license license:expat)))

(define-public r-rcmdcheck
  (package
    (name "r-rcmdcheck")
    (version "1.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rcmdcheck" version))
       (sha256
        (base32
         "1d4kzgfqy72r6b7bn1j4znyksrycgypx1jjvpv9lrmvn37mpkdhs"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-callr" ,r-callr)
       ("r-cli" ,r-cli)
       ("r-crayon" ,r-crayon)
       ("r-desc" ,r-desc)
       ("r-digest" ,r-digest)
       ("r-pkgbuild" ,r-pkgbuild)
       ("r-prettyunits" ,r-prettyunits)
       ("r-r6" ,r-r6)
       ("r-rprojroot" ,r-rprojroot)
       ("r-sessioninfo" ,r-sessioninfo)
       ("r-withr" ,r-withr)
       ("r-xopen" ,r-xopen)))
    (home-page "https://github.com/r-Lib/rcmdcheck#readme")
    (synopsis "Run R CMD check from R and capture results")
    (description
     "Run @code{R CMD check} from R programmatically, and capture the results
of the individual checks.")
    (license license:expat)))

(define-public r-rapportools
  (package
    (name "r-rapportools")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rapportools" version))
       (sha256
        (base32
         "1sgv4sc737i12arh5dc3263kjsz3dzg06qihfmrqyax94mv2d01b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-pander" ,r-pander)
       ("r-plyr" ,r-plyr)
       ("r-reshape" ,r-reshape)))
    (home-page "https://cran.r-project.org/web/packages/rapportools/")
    (synopsis "Miscellaneous helper functions with sane defaults for reporting")
    (description
     "This package provides helper functions that act as wrappers to more
advanced statistical methods with the advantage of having sane defaults for
quick reporting.")
    (license license:agpl3+)))

(define-public r-pander
  (package
    (name "r-pander")
    (version "0.6.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pander" version))
       (sha256
        (base32
         "1bd9sdghlsppmff18k5fg3i0visq9f4wc82rlhwq5m82bmgdgnyi"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://rapporter.github.io/pander")
    (synopsis "Render R objects into Pandoc's markdown")
    (description
     "The main aim of the pander R package is to provide a minimal and easy
tool for rendering R objects into Pandoc's markdown.  The package is also
capable of exporting/converting complex Pandoc documents (reports) in various
ways.")
    ;; This package is licensed under either the AGPLv3+ or the very rarely
    ;; used OSL 3.0.
    (license license:agpl3+)))

(define-public r-summarytools
  (package
    (name "r-summarytools")
    (version "0.9.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "summarytools" version))
       (sha256
        (base32
         "03pcb2ild1rb9f15yq8b68p9bg10z5wk2x7ahgyzkwdh5f81vbq2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-checkmate" ,r-checkmate)
       ("r-dplyr" ,r-dplyr)
       ("r-htmltools" ,r-htmltools)
       ("r-lubridate" ,r-lubridate)
       ("r-magick" ,r-magick)
       ("r-matrixstats" ,r-matrixstats)
       ("r-pander" ,r-pander)
       ("r-pryr" ,r-pryr)
       ("r-rapportools" ,r-rapportools)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/dcomtois/summarytools")
    (synopsis "Tools to quickly and neatly summarize data")
    (description
     "This package provides tools for data frame summaries, cross-tabulations,
weight-enabled frequency tables and common univariate statistics in concise
tables available in a variety of formats (plain ASCII, Markdown and HTML).  A
good point-of-entry for exploring data, both for experienced and new R
users.")
    (license license:gpl2)))

(define-public r-lsei
  (package
    (name "r-lsei")
    (version "1.2-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lsei" version))
       (sha256
        (base32
         "1xl06fb3is744pxlh42wx5hn1h0ab1k31wnmsmh0524kxzcyp0a7"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://www.stat.auckland.ac.nz/~yongwang")
    (synopsis "Solve regression problems under equality/inequality constraints")
    (description
     "It contains functions that solve least squares linear regression
problems under linear equality/inequality constraints.  Functions for solving
quadratic programming problems are also available, which transform such
problems into least squares ones first.")
    (license license:gpl2+)))

(define-public r-npsurv
  (package
    (name "r-npsurv")
    (version "0.4-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "npsurv" version))
       (sha256
        (base32
         "1wq4c9yfha5azjhrn40iiqkshmvh611sa90jp3lh82n4bl9zfk20"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lsei" ,r-lsei)))
    (home-page "https://www.stat.auckland.ac.nz/~yongwang")
    (synopsis "Nonparametric survival analysis")
    (description
     "This package contains functions for non-parametric survival analysis of
exact and interval-censored observations.")
    (license license:gpl2+)))

(define-public r-clusteval
  (package
    (name "r-clusteval")
    (version "0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "clusteval" version))
       (sha256
        (base32
         "1ld0bdl4fy8dsfzm3k7a37cyxc6pfc9qs31x4pxd3z5rslghz7rj"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mvtnorm" ,r-mvtnorm)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/clusteval/")
    (synopsis "Evaluation of clustering algorithms")
    (description
     "This R package provides a suite of tools to evaluate clustering
algorithms, clusterings, and individual clusters.")
    (license license:expat)))

(define-public r-tweedie
  (package
    (name "r-tweedie")
    (version "2.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tweedie" version))
       (sha256
        (base32
         "10fv998qjxsyx0h94fi0xbh6xbf24nwgh254n9zfnmix9vk2cqls"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/tweedie/")
    (synopsis "Evaluation of Tweedie exponential family models")
    (description
     "Maximum likelihood computations for Tweedie families, including the
series expansion (Dunn and Smyth, 2005; <doi10.1007/s11222-005-4070-y>) and
the Fourier inversion (Dunn and Smyth, 2008; <doi:10.1007/s11222-007-9039-6>),
and related methods.")
    (license license:gpl2+)))

(define-public r-rcppgsl
  (package
    (name "r-rcppgsl")
    (version "0.3.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RcppGSL" version))
       (sha256
        (base32 "0cnw2k7cfqrm79r6j283aybflxig80x4n4rjkfp2317wf10mrsa5"))))
    (properties `((upstream-name . "RcppGSL")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("gsl" ,gsl)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))           ; for vignettes
    (home-page "https://cran.r-project.org/web/packages/RcppGSL/")
    (synopsis "Rcpp integration for GSL vectors and matrices")
    (description
     "The GNU Scientific Library (or GSL) is a collection of numerical
routines for scientific computing.  It is particularly useful for C and C++
programs as it provides a standard C interface to a wide range of mathematical
routines.  There are over 1000 functions in total with an extensive test
suite.  The RcppGSL package provides an easy-to-use interface between GSL data
structures and R using concepts from Rcpp which is itself a package that eases
the interfaces between R and C++.")
    (license license:gpl2+)))

(define-public r-mvabund
  (package
    (name "r-mvabund")
    (version "4.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mvabund" version))
       (sha256
        (base32
         "1z58h4dk3mc2hfnfvc7pghk471cbp7ah2s1z2ria5igw4s80962b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppgsl" ,r-rcppgsl)
       ("r-statmod" ,r-statmod)
       ("r-tweedie" ,r-tweedie)))
    (home-page "https://cran.r-project.org/web/packages/mvabund/")
    (synopsis "Statistical methods for analysing multivariate abundance data")
    (description
     "This package provides a set of tools for displaying, modeling and
analysing multivariate abundance data in community ecology.")
    (license license:lgpl2.1+)))

(define-public r-afex
  (package
    (name "r-afex")
    (version "0.26-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "afex" version))
       (sha256
        (base32
         "0h3p1svgk1ap3lj08fi8nzdb3710h99bv150krf1x8wci1a0r1if"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-car" ,r-car)
       ("r-lme4" ,r-lme4)
       ("r-lmertest" ,r-lmertest)
       ("r-pbkrtest" ,r-pbkrtest)
       ("r-reshape2" ,r-reshape2)))
    (home-page "https://afex.singmann.science/")
    (synopsis "Analysis of factorial experiments")
    (description
     "This package provides convenience functions for analyzing factorial
experiments using ANOVA or mixed models.")
    (license license:gpl2+)))

(define-public r-lmertest
  (package
    (name "r-lmertest")
    (version "3.1-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lmerTest" version))
       (sha256
        (base32
         "0r2vvs3nl6p8xla3gd943khb4ixp0alvspqpnz2y6n3wk8zgh3jj"))))
    (properties `((upstream-name . "lmerTest")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-lme4" ,r-lme4)
       ("r-mass" ,r-mass)
       ("r-numderiv" ,r-numderiv)))
    (home-page "https://github.com/runehaubo/lmerTestR")
    (synopsis "Tests in linear mixed effects models")
    (description
     "This package provides p-values in type I, II or III anova and summary
tables for @code{lmer} model fits via Satterthwaite's degrees of freedom
method.  A Kenward-Roger method is also available via the @code{pbkrtest}
package.  Model selection methods include step, drop1 and anova-like tables
for random effects (ranova).  Methods for Least-Square means (LS-means) and
tests of linear contrasts of fixed effects are also available.")
    (license license:gpl2+)))

(define-public r-r2glmm
  (package
    (name "r-r2glmm")
    (version "0.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "r2glmm" version))
       (sha256
        (base32
         "0iim92blpa59vgz97c2pi05yhbjjmaffdbkbmk5kplfb2vmazgiy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-afex" ,r-afex)
       ("r-data-table" ,r-data-table)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-lmertest" ,r-lmertest)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-mgcv" ,r-mgcv)
       ("r-pbkrtest" ,r-pbkrtest)))
    (home-page "https://github.com/bcjaeger/r2glmm")
    (synopsis "Compute R squared for mixed (multilevel) models")
    (description
     "This package computes model and semi partial R squared with confidence
limits for the linear and generalized linear mixed model (LMM and GLMM).  The
R squared measure from L. J. Edwards et al. (2008) is extended to the GLMM
using @dfn{penalized quasi-likelihood} (PQL) estimation (see Jaeger et
al. (2016)).")
    (license license:gpl2)))

(define-public r-weights
  (package
    (name "r-weights")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "weights" version))
       (sha256
        (base32
         "1ka2kvzg464vn80qziqy4mrciy9wwd3jfasgq0d33wbiblhmxkj5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gdata" ,r-gdata)
       ("r-hmisc" ,r-hmisc)
       ("r-mice" ,r-mice)))
    (home-page
     "https://cran.r-project.org/web/packages/weights/")
    (synopsis "Weighting and weighted statistics")
    (description "This package Provides a variety of functions for producing
simple weighted statistics, such as weighted Pearson's correlations, partial
correlations, Chi-Squared statistics, histograms, and t-tests.  Also now
includes some software for quickly recoding survey data and plotting point
estimates from interaction terms in regressions (and multiply imputed
regressions).  NOTE: Weighted partial correlation calculations pulled to
address a bug.")
  (license license:gpl2+)))

(define-public r-rcppannoy
  (package
    (name "r-rcppannoy")
    (version "0.0.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RcppAnnoy" version))
       (sha256
        (base32
         "0bfa35lp6vc4b0h3ymvdx50br233q8vvyjml34ngi81rj0imz3fr"))))
    (properties `((upstream-name . "RcppAnnoy")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/RcppAnnoy/")
    (synopsis "Rcpp bindings for Annoy, a library for Approximate Nearest Neighbors")
    (description
     "Annoy is a small C++ library for Approximate Nearest Neighbors written
for efficient memory usage as well an ability to load from and save to disk.
This package provides an R interface.")
    ;; Annoy is released under ASL 2.0, but this wrapper is released under
    ;; GPLv2+.
    (license (list license:gpl2+ license:asl2.0))))

(define-public r-rcpphnsw
  (package
    (name "r-rcpphnsw")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RcppHNSW" version))
       (sha256
        (base32
         "0gqdkw7vkcm544rz45g0hplg836ygzbfwk9gh9wr0817icvdb3qv"))))
    (properties `((upstream-name . "RcppHNSW")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/RcppHNSW/")
    (synopsis "Rcpp bindings for hnswlib, a library for approximate nearest neighbors")
    (description
     "Hnswlib is a C++ library for approximate nearest neighbors.  This
package provides a minimal R interface by relying on the Rcpp package.")
    ;; hnswlib is released under Version 2.0 of the Apache License.
    (license (list license:gpl3 license:asl2.0))))

(define-public r-rcppparallel
  (package
    (name "r-rcppparallel")
    (version "5.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RcppParallel" version))
       (sha256
        (base32
         "1mhd6vp47xmfw533h0pkvydv96m57fspvd85g8m7iqb5rcxvhhdb"))))
    (properties `((upstream-name . "RcppParallel")))
    (build-system r-build-system)
    (home-page "https://rcppcore.github.io/RcppParallel/")
    (synopsis "Parallel programming tools for Rcpp")
    (description
     "This package provides high level functions for parallel programming with
Rcpp.  For example, the @code{parallelFor()} function can be used to convert
the work of a standard serial @code{for} loop into a parallel one and the
@code{parallelReduce()} function can be used for accumulating aggregates or
other values.")
    (license license:gpl2)))

(define-public r-ncdf4
  (package
    (name "r-ncdf4")
    (version "1.17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ncdf4" version))
       (sha256
        (base32
         "1xls44ln2zjrrlimxl8v4bk2ni3g45c9j0gxdnjx31rikmrc95fv"))))
    (build-system r-build-system)
    (inputs
     `(("netcdf" ,netcdf)
       ("zlib" ,zlib)))
    (home-page "https://cran.r-project.org/web/packages/ncdf4/index.html")
    (synopsis "R interface to Unidata netCDF format data files")
    (description
     "This package provides a high-level R interface to data files written
using Unidata's netCDF library (version 4 or earlier), which are binary data
files that are portable across platforms and include metadata information in
addition to the data sets.  Using this package, netCDF files can be opened and
data sets read in easily.  It is also easy to create new netCDF dimensions,
variables, and files, in either version 3 or 4 format, and manipulate existing
netCDF files.")
    (license license:gpl3+)))

(define-public r-biocmanager
  (package
    (name "r-biocmanager")
    (version "1.30.10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "BiocManager" version))
       (sha256
        (base32 "03n9s2vf7vgpgb5alpxwamf9xfkn32cbzngwyn6spq1bnh9a9dzk"))))
    (properties `((upstream-name . "BiocManager")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/BiocManager/")
    (synopsis "Access the Bioconductor project package repository")
    (description
     "This package provides a convenient tool to install and update
Bioconductor packages.")
    (license license:artistic2.0)))

(define-public r-rgl
  (package
    (name "r-rgl")
    (version "0.100.50")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rgl" version))
       (sha256
        (base32
         "165p932ml7dpjkm41zc47p5cdxar69il0m5yvg0avi8q01vr17ay"))))
    (build-system r-build-system)
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (inputs
     `(("freetype" ,freetype)
       ("libpng" ,libpng)
       ("glu" ,glu)
       ("libx11" ,libx11)
       ("ghc-pandoc" ,ghc-pandoc)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-crosstalk" ,r-crosstalk)
       ("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-magrittr" ,r-magrittr)
       ("r-manipulatewidget" ,r-manipulatewidget)
       ("r-shiny" ,r-shiny)))
    (home-page "https://r-forge.r-project.org/projects/rgl/")
    (synopsis "3D visualization using OpenGL")
    (description
     "This package provides medium to high level functions for 3D interactive graphics,
including functions modelled on base graphics (@code{plot3d()}, etc.) as well
as functions for constructing representations of geometric
objects (@code{cube3d()}, etc.).  Output may be on screen using OpenGL, or to
various standard 3D file formats including WebGL, PLY, OBJ, STL as well as 2D
image formats, including PNG, Postscript, SVG, PGF.")
    ;; Any version of the GPL.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-multicool
  (package
    (name "r-multicool")
    (version "0.1-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "multicool" version))
       (sha256
        (base32
         "0xk408qbz9cxwf51j3pmy55gcjcnws8mc6j3vyn9zhramxj7x40w"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/multicool/")
    (synopsis "Permutations of multisets in cool-lex order")
    (description
     "This package provides a set of tools to permute multisets without loops
or hash tables and to generate integer partitions.  Cool-lex order is similar
to colexicographical order.")
    (license license:gpl2)))

(define-public r-misc3d
  (package
    (name "r-misc3d")
    (version "0.8-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "misc3d" version))
       (sha256
        (base32
         "0qjzpw3h09qi2gfz52b7nhzd95p7yyxsd03fldc9wzzn6wi3vpkm"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/misc3d/")
    (synopsis "Miscellaneous 3D Plots")
    (description
     "This package provides a collection of miscellaneous 3d plots, including
isosurfaces.")
    ;; Any version of the GPL.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-ks
  (package
    (name "r-ks")
    (version "1.11.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ks" version))
       (sha256
        (base32 "1f6jvxy0hmngyvnvrknzbmhl42njk0vqyycvydm4qnp8cqirqvba"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fnn" ,r-fnn)
       ("r-kernlab" ,r-kernlab)
       ("r-kernsmooth" ,r-kernsmooth)
       ("r-matrix" ,r-matrix)
       ("r-mclust" ,r-mclust)
       ("r-mgcv" ,r-mgcv)
       ("r-multicool" ,r-multicool)
       ("r-mvtnorm" ,r-mvtnorm)))
    (home-page "http://www.mvstat.net/tduong/")
    (synopsis "Kernel smoothing")
    (description
     "This package provides kernel smoothers for univariate and multivariate
data, including density functions, density derivatives, cumulative
distributions, modal clustering, discriminant analysis, and two-sample
hypothesis testing.")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

(define-public r-feature
  (package
    (name "r-feature")
    (version "1.2.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "feature" version))
       (sha256
        (base32
         "07hkw0bv38naj2hdsx4xxrm2dngi6w3rbvgr7s50bjic8hlgy1ra"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ks" ,r-ks)
       ("r-misc3d" ,r-misc3d)
       ("r-rgl" ,r-rgl)))
    (home-page "http://www.mvstat.net/tduong/")
    (synopsis "Inferential feature significance for kernel density estimation")
    (description
     "The feature package contains functions to display and compute kernel
density estimates, significant gradient and significant curvature regions.
Significant gradient and/or curvature regions often correspond to significant
features (e.g. local modes).")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

(define-public r-arm
  (package
    (name "r-arm")
    (version "1.10-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "arm" version))
       (sha256
        (base32
         "0vvp90jygajd6ydky57z66wqjq9msfbl88irj5jbsray574mh4bg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)
       ("r-coda" ,r-coda)
       ("r-lme4" ,r-lme4)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-nlme" ,r-nlme)))
    (home-page "https://cran.r-project.org/web/packages/arm/")
    (synopsis "Data analysis using regression and multilevel/hierarchical models")
    (description
     "This package provides functions to accompany A. Gelman and J. Hill,
Data Analysis Using Regression and Multilevel/Hierarchical Models, Cambridge
University Press, 2007.")
    (license license:gpl3+)))

(define-public r-circular
  (package
    (name "r-circular")
    (version "0.4-93")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "circular" version))
       (sha256
        (base32
         "0hki85rs8wc5950pjaw28q54rly2napfbcrx3pchlfap6wwy5kkn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-mvtnorm" ,r-mvtnorm)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/circular/")
    (synopsis "Circular statistics")
    (description
     "This package provides tools for circular statistics, from \"Topics in
circular Statistics\" (2001) S. Rao Jammalamadaka and A. SenGupta, World
Scientific.")
    (license license:gpl2+)))

(define-public r-activity
  (package
    (name "r-activity")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "activity" version))
       (sha256
        (base32
         "12imqj366dp6pam5gap6ji56p5wf1073xz5g4iikfxf5l8snxw92"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-circular" ,r-circular)
       ("r-insol" ,r-insol)
       ("r-pbapply" ,r-pbapply)))
    (home-page "https://cran.r-project.org/web/packages/activity/")
    (synopsis "Animal activity statistics")
    (description
     "This package provides functions to fit kernel density functions to
animal activity time data; plot activity distributions; quantify overall
levels of activity; statistically compare activity metrics through
bootstrapping; and evaluate variation in linear variables with time (or other
circular variables).")
    (license license:gpl3)))

(define-public r-ouch
  (package
    (name "r-ouch")
    (version "2.14-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ouch" version))
       (sha256
        (base32
         "0ddf9bw5lhj8vb0ja78jf99i0smq4rgmm842k4a4ygap41vdyn2b"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-subplex" ,r-subplex)))
    (home-page "https://kingaa.github.io/ouch/")
    (synopsis "Ornstein-Uhlenbeck models for phylogenetic comparative hypotheses")
    (description
     "This package provides tools to fit and compare Ornstein-Uhlenbeck models
for evolution along a phylogenetic tree.")
    (license license:gpl2+)))

(define-public r-fmsb
  (package
    (name "r-fmsb")
    (version "0.7.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fmsb" version))
       (sha256
        (base32
         "0x1wkzfdvv4s5xmr0whcwjz4aac71gacwymj2c3mzj2bbswwlw45"))))
    (build-system r-build-system)
    (home-page "http://minato.sip21c.org/msb/")
    (synopsis "Functions for medical statistics book with demographic data")
    (description
     "This package provides several utility functions for the book entitled
\"Practices of Medical and Health Data Analysis using R\" (Pearson Education
Japan, 2007) with Japanese demographic data and some demographic analysis
related functions.")
    (license license:gpl2+)))

(define-public r-stabledist
  (package
    (name "r-stabledist")
    (version "0.7-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "stabledist" version))
       (sha256
        (base32
         "0scar396wiq6wkbkvwp4qrxqc1m075y56p37i6iry5rw796p1i86"))))
    (build-system r-build-system)
    (home-page "https://www.rmetrics.org")
    (synopsis "Stable distribution functions")
    (description
     "This package provides density, probability and quantile functions, and
random number generation for (skew) stable distributions, using the
parametrizations of Nolan.")
    (license license:gpl2+)))

(define-public r-gsl
  (package
    (name "r-gsl")
    (version "2.1-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gsl" version))
       (sha256
        (base32
         "0p4rh7npp6qbfc5sxjq86xjn7c9ivf3pd60qf1hldwckjqin7m7m"))))
    (build-system r-build-system)
    (inputs
     `(("gsl" ,gsl)))
    (home-page "https://cran.r-project.org/web/packages/gsl")
    (synopsis "Wrapper for the GNU Scientific Library")
    (description
     "This package provides an R wrapper for the special functions and quasi
random number generators of the GNU Scientific Library.")
    (license license:gpl2+)))

(define-public r-adgoftest
  (package
    (name "r-adgoftest")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ADGofTest" version))
       (sha256
        (base32
         "0ik817qzqp6kfbckjp1z7srlma0w6z2zcwykh0jdiv7nahwk3ncw"))))
    (properties `((upstream-name . "ADGofTest")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ADGofTest")
    (synopsis "Anderson-Darling GoF test")
    (description
     "This package provides an implementation of the Anderson-Darling GoF test
with p-value calculation based on Marsaglia's 2004 paper \"Evaluating the
Anderson-Darling Distribution\".")
    ;; Any version of the GPL.
    (license license:gpl3+)))

(define-public r-softimpute
  (package
    (name "r-softimpute")
    (version "1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "softImpute" version))
       (sha256
        (base32
         "07cxbzkl08q58m1455i139952rmryjlic4s2f2hscl5zxxmfdxcq"))))
    (properties `((upstream-name . "softImpute")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/softImpute")
    (synopsis "Matrix completion via iterative soft-thresholded SVD")
    (description
     "This package provides iterative methods for matrix completion that use
nuclear-norm regularization.  The package includes procedures for centering
and scaling rows, columns or both, and for computing low-rank @dfn{single
value decompositions} (SVDs) on large sparse centered matrices (i.e. principal
components).")
    (license license:gpl2)))

(define-public r-fftwtools
  (package
    (name "r-fftwtools")
    (version "0.9-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fftwtools" version))
       (sha256
        (base32
         "1nqvpzda281rxi1cmwajxxsn3sc3gz7scv8bvs5jm34kf36whha6"))))
    (build-system r-build-system)
    (inputs `(("fftw" ,fftw)))
    (home-page "https://github.com/krahim/fftwtools")
    (synopsis "Wrapper for FFTW3")
    (description
     "This package provides a wrapper for several FFTW functions.  It provides
access to the two-dimensional FFT, the multivariate FFT, and the
one-dimensional real to complex FFT using the FFTW3 library.  The package
includes the functions @code{fftw()} and @code{mvfftw()} which are designed to
mimic the functionality of the R functions @code{fft()} and @code{mvfft()}.
The FFT functions have a parameter that allows them to not return the
redundant complex conjugate when the input is real data.")
    (license license:gpl2+)))

(define-public r-tiff
  (package
    (name "r-tiff")
    (version "0.1-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tiff" version))
       (sha256
        (base32
         "0asf2bws3x3yd3g3ixvk0f86b0mdf882pl8xrqlxrkbgjalyc54m"))))
    (build-system r-build-system)
    (inputs
     `(("libtiff" ,libtiff)
       ("libjpeg" ,libjpeg)
       ("zlib" ,zlib)))
    (home-page "https://www.rforge.net/tiff/")
    (synopsis "Read and write TIFF images")
    (description
     "This package provides an easy and simple way to read, write and display
bitmap images stored in the TIFF format.  It can read and write both files and
in-memory raw vectors.")
    ;; Either of these two license versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-nlp
  (package
    (name "r-nlp")
    (version "0.2-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "NLP" version))
       (sha256
        (base32
         "0xbhkrnxcbf322jfw31xcn4y2gnk5y7ccq1bz4h3prf44h0whr7w"))))
    (properties `((upstream-name . "NLP")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/NLP/")
    (synopsis "Natural language processing infrastructure")
    (description
     "This package provides basic classes and methods for Natural Language
Processing.")
    (license license:gpl3)))

(define-public r-tm
  (package
    (name "r-tm")
    (version "0.7-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tm" version))
       (sha256
        (base32
         "0pyics8j7a4wkh5gzin46l0qars5vgbb1886xqpdqjs1z0gy9nyh"))))
    (properties `((upstream-name . "tm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-nlp" ,r-nlp)
       ("r-rcpp" ,r-rcpp)
       ("r-slam" ,r-slam)
       ("r-xml2" ,r-xml2)))
    (home-page "http://tm.r-forge.r-project.org/")
    (synopsis "Text mining package")
    (description
     "This package provides a framework for text mining applications within R.")
    (license license:gpl3)))

(define-public r-waveslim
  (package
    (name "r-waveslim")
    (version "1.8.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "waveslim" version))
       (sha256
        (base32
         "0ibivnhz0l06sss5rrrcvyiwg3qpbyk3qn4vx4pp90kj09x4yg0k"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "http://waveslim.blogspot.com")
    (synopsis "Basic wavelet routines for signal processing")
    (description
     "This package provides basic wavelet routines for time series (1D),
image (2D) and array (3D) analysis.  The code provided here is based on
wavelet methodology developed in Percival and Walden (2000); Gencay, Selcuk
and Whitcher (2001); the dual-tree complex wavelet transform (DTCWT) from
Kingsbury (1999, 2001) as implemented by Selesnick; and Hilbert wavelet
pairs (Selesnick 2001, 2002).")
    (license license:bsd-3)))

(define-public r-wordcloud
  (package
    (name "r-wordcloud")
    (version "2.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "wordcloud" version))
       (sha256
        (base32
         "0j96yyvm6bcrrpbdx4w26piqx44a0vbsr3px9cb4zk8a8da6jwak"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-rcpp" ,r-rcpp)
       ;; The "tm" package is only "suggested" according to CRAN, but the
       ;; wordcloud package cannot be loaded without it.
       ("r-tm" ,r-tm)))
    (home-page "https://cran.r-project.org/web/packages/wordcloud")
    (synopsis "Word clouds")
    (description
     "This package provides functionality to create pretty word clouds,
visualize differences and similarity between documents, and avoid
over-plotting in scatter plots with text.")
    (license license:lgpl2.1)))

(define-public r-colorramps
  (package
    (name "r-colorramps")
    (version "2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "colorRamps" version))
       (sha256
        (base32
         "0shbjh83x1axv4drm5r3dwgbyv70idih8z4wlzjs4hiac2qfl41z"))))
    (properties `((upstream-name . "colorRamps")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/colorRamps")
    (synopsis "Build color tables")
    (description "This package provides features to build gradient color
maps.")
    ;; Any version of the GPL
    (license license:gpl3+)))

(define-public r-tidytree
  (package
    (name "r-tidytree")
    (version "0.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tidytree" version))
       (sha256
        (base32 "0dx9jn19mfykn20camsmq1amlgg0w6z5hn5rdqygs1fk1l5aazad"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ape" ,r-ape)
       ("r-dplyr" ,r-dplyr)
       ("r-lazyeval" ,r-lazyeval)
       ("r-magrittr" ,r-magrittr)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/GuangchuangYu/tidytree")
    (synopsis "Tidy tool for phylogenetic tree data manipulation")
    (description
     "Phylogenetic trees generally contain multiple components including nodes,
edges, branches and associated data.  This package provides an approach to
convert tree objects to tidy data frames.  It also provides tidy interfaces to
manipulate tree data.")
    (license license:artistic2.0)))

(define-public r-rvcheck
  (package
    (name "r-rvcheck")
    (version "0.1.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rvcheck" version))
       (sha256
        (base32 "0627bc8qmhxmd63yh6f90qni3qw1zwdpxjln2qbychzmzd4am9ac"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-biocmanager" ,r-biocmanager)
       ("r-rlang" ,r-rlang)))
    (home-page "https://cran.r-project.org/web/packages/rvcheck")
    (synopsis "R package version check")
    (description
     "This package provides tools to check the latest release version of R and
R packages (on CRAN, Bioconductor or Github).")
    (license license:artistic2.0)))

(define-public r-docopt
  (package
    (name "r-docopt")
    (version "0.6.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "docopt" version))
       (sha256
        (base32
         "06zknnd0c5s2y0hbddzdlr3m63ib783izpck6pgz7sjbab5pd068"))))
    (build-system r-build-system)
    (home-page "https://github.com/docopt/docopt.R")
    (synopsis "Command-line interface specification language")
    (description
     "This package enables you to define a command-line interface by just
giving it a description in the specific format.")
    (license license:expat)))

(define-public r-sparsesvd
  (package
    (name "r-sparsesvd")
    (version "0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sparsesvd" version))
       (sha256
        (base32
         "1xm969fjq3fv1p2sqza2apz8picibj4s2agpwf1sx9nwn3b587qs"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-matrix" ,r-matrix)))
    (home-page "http://tedlab.mit.edu/~dr/SVDLIBC/")
    (synopsis "Sparse truncated singular value decomposition")
    (description
     "This package provides a Wrapper around the SVDLIBC library
for (truncated) singular value decomposition of a sparse matrix.  Currently,
only sparse real matrices in Matrix package format are supported.")
    ;; SVDLIBC is released under BSD-2.  The R interface is released under
    ;; BSD-3.
    (license (list license:bsd-3 license:bsd-2))))

(define-public r-speedglm
  (package
    (name "r-speedglm")
    (version "0.3-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "speedglm" version))
       (sha256
        (base32
         "1b25zimk0z7ad62yacqdg0zk0qs0jja4i918ym942xfw4j1z3jjz"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/speedglm")
    (synopsis "Fit linear and generalized linear models to large data sets")
    (description
     "This package provides tools for fitting linear models and generalized
linear models to large data sets by updating algorithms.")
    ;; Any version of the GPL
    (license license:gpl2+)))

(define-public r-densityclust
  (package
    (name "r-densityclust")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "densityClust" version))
       (sha256
        (base32
         "1zry0vafajzmr37aylglxfvwplhdygbkb9cvzvh8cy0xgnjrnx13"))))
    (properties `((upstream-name . "densityClust")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fnn" ,r-fnn)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-gridextra" ,r-gridextra)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-rcpp" ,r-rcpp)
       ("r-rtsne" ,r-rtsne)))
    (home-page "https://cran.r-project.org/web/packages/densityClust")
    (synopsis "Clustering by fast search and find of density peaks")
    (description
     "This package provides an improved implementation (based on k-nearest
neighbors) of the density peak clustering algorithm, originally described by
Alex Rodriguez and Alessandro Laio (Science, 2014 vol. 344).  It can handle
large datasets (> 100,000 samples) very efficiently.")
    (license license:gpl2+)))

(define-public r-combinat
  (package
    (name "r-combinat")
    (version "0.0-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "combinat" version))
       (sha256
        (base32
         "1h9hr88gigihc4na7lb5i7rn4az1xa7sb34zvnznaj6pdrmwy4qm"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/combinat")
    (synopsis "Combinatorics utilities")
    (description "This package provides assorted routines for combinatorics.")
    (license license:gpl2)))

(define-public r-qlcmatrix
  (package
    (name "r-qlcmatrix")
    (version "0.9.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "qlcMatrix" version))
       (sha256
        (base32
         "0iqkcvvy8rxlk0s83sjq57dd6fadb18p5z31lzy0gnzv1hsy1x8y"))))
    (properties `((upstream-name . "qlcMatrix")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-docopt" ,r-docopt)
       ("r-matrix" ,r-matrix)
       ("r-slam" ,r-slam)
       ("r-sparsesvd" ,r-sparsesvd)))
    (home-page "https://cran.r-project.org/web/packages/qlcMatrix")
    (synopsis "Sparse matrix functions for quantitative language comparison")
    (description
     "This package provides an extension of the functionality of the Matrix
package for using sparse matrices.  Some of the functions are very general,
while other are highly specific for the special data format used for
@dfn{quantitative language comparison} (QLC).")
    (license license:gpl3)))

(define-public r-ddrtree
  (package
    (name "r-ddrtree")
    (version "0.1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "DDRTree" version))
       (sha256
        (base32
         "16s5fjw7kwlxhrkzdny62sx32fvmg3rxjc3wrh6krd31jh1fqlfk"))))
    (properties `((upstream-name . "DDRTree")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-irlba" ,r-irlba)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "https://cran.r-project.org/web/packages/DDRTree")
    (synopsis "Learning principal graphs with DDRTree")
    (description
     "This package provides an implementation of the framework of
@dfn{reversed graph embedding} (RGE) which projects data into a reduced
dimensional space while constructs a principal tree which passes through the
middle of the data simultaneously.  DDRTree shows superiority to
alternatives (Wishbone, DPT) for inferring the ordering as well as the
intrinsic structure of single cell genomics data.  In general, it could be
used to reconstruct the temporal progression as well as the bifurcation
structure of any data type.")
    (license license:asl2.0)))

(define-public r-corpcor
  (package
    (name "r-corpcor")
    (version "1.6.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "corpcor" version))
       (sha256
        (base32
         "1hi3i9d3841snppq1ks5pd8cliq1b4rm4dpsczmfqvwksg8snkrf"))))
    (build-system r-build-system)
    (home-page "http://strimmerlab.org/software/corpcor/")
    (synopsis "Efficient estimation of covariance and (partial) correlation")
    (description
     "This package implements a James-Stein-type shrinkage estimator for the
covariance matrix, with separate shrinkage for variances and correlations.
Furthermore, functions are available for fast singular value decomposition,
for computing the pseudoinverse, and for checking the rank and positive
definiteness of a matrix.")
    (license license:gpl3+)))

(define-public r-rspectra
  (package
    (name "r-rspectra")
    (version "0.16-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RSpectra" version))
       (sha256
        (base32
         "1ab45as2ysjrvkhvmx7y3nbhd0y1w4j9k2a789lcd973zz4wzwda"))))
    (properties `((upstream-name . "RSpectra")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "https://github.com/yixuan/RSpectra")
    (synopsis "Solvers for large-scale Eigenvalue and SVD problems")
    (description
     "This package provides an R interface to the Spectra library for
large-scale eigenvalue and SVD problems.  It is typically used to compute a
few eigenvalues/vectors of an n by n matrix, e.g., the k largest eigenvalues,
which is usually more efficient than @code{eigen()} if k << n.")
    ;; MPL 2 or later.
    (license license:mpl2.0)))

(define-public r-vbsr
  (package
    (name "r-vbsr")
    (version "0.0.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "vbsr" version))
       (sha256
        (base32
         "1avskbxxyinjjdga4rnghcfvd4sypv4m39ysfaij5avvmi89bx3b"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/vbsr")
    (synopsis "Variational Bayes spike regression regularized linear models")
    (description
     "This package provides an efficient algorithm for solving ultra-sparse
regularized regression models using a variational Bayes algorithm with a spike
prior.  The algorithm is solved on a path, with coordinate updates, and is
capable of generating very sparse models.  Very general model
diagnostics for controlling type-1 errors are also provided.")
    (license license:gpl2)))

(define-public r-flare
  (package
    (name "r-flare")
    (version "1.6.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flare" version))
       (sha256
        (base32
         "1ybrsx1djqldw0l5l1iz4pfh6xxb8ckkg1ric7wnsr51wm9ljlh5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/flare")
    (synopsis "Family of Lasso regression implementations")
    (description
     "This package provides implementations of a family of Lasso variants
including Dantzig Selector, LAD Lasso, SQRT Lasso, Lq Lasso for estimating
high dimensional sparse linear models.")
    (license license:gpl2)))

(define-public r-lassopv
  (package
    (name "r-lassopv")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lassopv" version))
       (sha256
        (base32
         "0yawnjw063jypk3riy9xab9cmliv6c9dnabi18670khd3gzb2r9z"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-lars" ,r-lars)))
    (home-page "https://github.com/lingfeiwang/lassopv")
    (synopsis "Non-parametric p-value estimation for predictors in Lasso")
    (description
     "This package enables you to estimate the p-values for predictors x
against target variable y in Lasso regression, using the regularization
strength when each predictor enters the active set of regularization path for
the first time as the statistic.")
    (license license:gpl3)))

(define-public r-splitstackshape
  (package
    (name "r-splitstackshape")
    (version "1.4.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "splitstackshape" version))
       (sha256
        (base32
         "0mpyf2kkfdl69pdc6brl1r6101vyc6pgr7z17s55ppg3y71k4q35"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)))
    (home-page "https://github.com/mrdwab/splitstackshape")
    (synopsis "Stack and reshape datasets after splitting concatenated values")
    (description
     "Online data collection tools like Google Forms often export
multiple-response questions with data concatenated in cells.  The
@code{concat.split} (cSplit) family of functions provided by this package
splits such data into separate cells.  This package also includes functions to
stack groups of columns and to reshape wide data, even when the data are
\"unbalanced\"---something which @code{reshape} (from base R) does not handle,
and which @code{melt} and @code{dcast} from @code{reshape2} do not easily
handle.")
    (license license:gpl3)))

(define-public r-tfmpvalue
  (package
    (name "r-tfmpvalue")
    (version "0.0.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TFMPvalue" version))
       (sha256
        (base32
         "0h9qkl15k8v17v3g9bdnfwvh2s04ywjgg5y0xn2077dmywlja1bd"))))
    (properties `((upstream-name . "TFMPvalue")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/ge11232002/TFMPvalue")
    (synopsis "P-value computation for position weight matrices")
    (description
     "In putative @dfn{Transcription Factor Binding Sites} (TFBSs)
identification from sequence/alignments, we are interested in the significance
of certain match scores.  TFMPvalue provides the accurate calculation of a
p-value with a score threshold for position weight matrices, or the score with
a given p-value.  It is an interface to code originally made available by
Helene Touzet and Jean-Stephane Varre, 2007, Algorithms Mol Biol:2, 15.
Touzet and Varre (2007).")
    (license license:gpl2)))

(define-public r-rnifti
  (package
    (name "r-rnifti")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RNifti" version))
       (sha256
        (base32
         "1z8ninp3aq18w0slcfn8r2fp48cdz8l0k0namsrnvgyp8lzcpqpn"))))
    (properties `((upstream-name . "RNifti")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/jonclayden/RNifti")
    (synopsis "Fast R and C++ access to NIfTI images")
    (description
     "This package provides very fast read and write access to images stored
in the NIfTI-1 and ANALYZE-7.5 formats, with seamless synchronisation between
compiled C and interpreted R code.  It also provides a C/C++ API that can be
used by other packages.")
    (license license:gpl2)))

(define-public r-shades
  (package
    (name "r-shades")
    (version "1.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shades" version))
       (sha256
        (base32
         "1zg95sjhrfvbdlfc387g9p0vnb8nb6agdk1mb3wq3kwkm2da0bqj"))))
    (build-system r-build-system)
    (home-page "https://github.com/jonclayden/shades")
    (synopsis "Simple color manipulation")
    (description
     "This package provides functions for easily manipulating colors,
creating color scales and calculating color distances.")
    (license license:bsd-3)))

(define-public r-ore
  (package
    (name "r-ore")
    (version "1.6.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ore" version))
       (sha256
        (base32 "1vh6w3arrhgkfjjjw7ci91xmz4wpfr3cmwd5zkqch89dgn07skkv"))))
    (build-system r-build-system)
    (home-page "https://github.com/jonclayden/ore")
    (synopsis "R interface to the Onigmo regular expression library")
    (description
     "This package provides an alternative to R's built-in functionality for
handling regular expressions, based on the Onigmo library.  It offers
first-class compiled regex objects, partial matching and function-based
substitutions, amongst other features.")
    (license license:bsd-3)))

(define-public r-reportr
  (package
    (name "r-reportr")
    (version "1.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "reportr" version))
       (sha256
        (base32
         "0zynplxqvbmf23cm2rsz3wz2jx6mv55z94mn1k44ny3lx625cnpw"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-ore" ,r-ore)))
    (home-page "https://github.com/jonclayden/reportr")
    (synopsis "General message and error reporting system")
    (description
     "This package provides a system for reporting messages, which offers
certain useful features over the standard R system, such as the incorporation
of output consolidation, message filtering, assertions, expression
substitution, automatic generation of stack traces for debugging, and
conditional reporting based on the current \"output level\".")
    (license license:gpl2)))

(define-public r-tractor-base
  (package
    (name "r-tractor-base")
    (version "3.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tractor.base" version))
       (sha256
        (base32
         "0y5gm0y4chl30f5qqq8qiiw4j8g32s4i9xrvyp3cwg902kf2p86i"))))
    (properties `((upstream-name . "tractor.base")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ore" ,r-ore)
       ("r-reportr" ,r-reportr)
       ("r-rnifti" ,r-rnifti)
       ("r-shades" ,r-shades)))
    (home-page "https://www.tractor-mri.org.uk")
    (synopsis "Read, manipulate and visualize magnetic resonance images")
    (description
     "This package provides functions for working with magnetic resonance
images.  It supports reading and writing of popular file formats (DICOM,
Analyze, NIfTI-1, NIfTI-2, MGH); interactive and non-interactive
visualization; flexible image manipulation; metadata and sparse image
handling.")
    (license license:gpl2)))

(define-public r-grimport
  (package
    (name "r-grimport")
    (version "0.9-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "grImport" version))
       (sha256
        (base32
         "109mrdvq06xq3zgn9ngz0c7zzgqkv5zbpvsb2i636vmlk6y4dpkd"))))
    (properties `((upstream-name . "grImport")))
    (build-system r-build-system)
    (inputs
     `(("ghostscript" ,ghostscript)))
    (propagated-inputs
     `(("r-xml" ,r-xml)))
    (home-page "https://cran.r-project.org/web/packages/grImport")
    (synopsis "Convert, import, and draw PostScript pictures")
    (description
     "This package provides functions for converting, importing, and drawing
PostScript pictures in R plots.")
    (license license:gpl2+)))

(define-public r-grimport2
  (package
    (name "r-grimport2")
    (version "0.2-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "grImport2" version))
       (sha256
        (base32
         "19q0dd8fpp1g4xf6sg5f8dxybwxjfw553ra6wgjd8b74fzca40m1"))))
    (properties `((upstream-name . "grImport2")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-jpeg" ,r-jpeg)
       ("r-png" ,r-png)
       ("r-xml" ,r-xml)))
    (home-page "https://cran.r-project.org/web/packages/grImport2/")
    (synopsis "Import SVG graphics")
    (description
     "This package provides functions for importing external vector images and
drawing them as part of R plots.  This package is different from the
@code{grImport} package because, where that package imports PostScript format
images, this package imports SVG format images.  Furthermore, this package
imports a specific subset of SVG, so external images must be preprocessed
using a package like @code{rsvg} to produce SVG that this package can import.
SVG features that are not supported by R graphics, such as gradient fills, can
be imported and then exported via the @code{gridSVG} package.")
    (license license:gpl2+)))

(define-public r-kohonen
  (package
    (name "r-kohonen")
    (version "3.0.10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kohonen" version))
       (sha256
        (base32
         "1ck7j13x701g67bx81x7plszz804jfhl1yg42krcj9x88vm5cscr"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/kohonen")
    (synopsis "Supervised and unsupervised self-organising maps")
    (description
     "This package provides functions to train @dfn{self-organising
maps} (SOMs).  Also interrogation of the maps and prediction using trained
maps are supported.  The name of the package refers to Teuvo Kohonen, the
inventor of the SOM.")
    (license license:gpl2+)))

(define-public r-nnls
  (package
    (name "r-nnls")
    (version "1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "nnls" version))
       (sha256
        (base32
         "07vcrrxvswrvfiha6f3ikn640yg0m2b4yd9lkmim1g0jmsmpfp8f"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/nnls")
    (synopsis "Lawson-Hanson algorithm for non-negative least squares")
    (description
     "This package provides an R interface to the Lawson-Hanson implementation
of an algorithm for @dfn{non-negative least squares} (NNLS).  It also allows
the combination of non-negative and non-positive constraints.")
    (license license:gpl2+)))

(define-public r-iso
  (package
    (name "r-iso")
    (version "0.0-18")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Iso" version))
       (sha256
        (base32
         "014mm5b1f7i6nwlz3kyg1biph0y542kcx5bd13p68cv5a928qzid"))))
    (properties `((upstream-name . "Iso")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://www.stat.auckland.ac.nz/~rolf/")
    (synopsis "Functions to perform isotonic regression")
    (description
     "This package provides support for linear order and unimodal
order (univariate) isotonic regression and bivariate isotonic regression with
linear order on both variables.")
    (license license:gpl2+)))

(define-public r-chemometricswithr
  (package
    (name "r-chemometricswithr")
    (version "0.1.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ChemometricsWithR" version))
       (sha256
        (base32
         "166va1g3m1wv21qkmw4wpz0bsrclh3jih8smxphdc13l9pqgclpq"))))
    (properties
     `((upstream-name . "ChemometricsWithR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-devtools" ,r-devtools)
       ("r-kohonen" ,r-kohonen)
       ("r-mass" ,r-mass)
       ("r-pls" ,r-pls)))
    (home-page "https://github.com/rwehrens/CWR")
    (synopsis "Chemometrics with R")
    (description
     "This package provides functions and scripts used in the book
\"Chemometrics with R - Multivariate Data Analysis in the Natural Sciences and
Life Sciences\" by Ron Wehrens, Springer (2011).")
    (license license:gpl2+)))

(define-public r-als
  (package
    (name "r-als")
    (version "0.0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ALS" version))
       (sha256
        (base32
         "1swrn39vy50fazkpf97r7c542gkj6mlvy8gmcxllg7mf2mqx546a"))))
    (properties `((upstream-name . "ALS")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-iso" ,r-iso)
       ("r-nnls" ,r-nnls)))
    (home-page "https://cran.r-project.org/web/packages/ALS")
    (synopsis "Multivariate curve resolution alternating least squares")
    (description
     "Alternating least squares is often used to resolve components
contributing to data with a bilinear structure; the basic technique may be
extended to alternating constrained least squares.  This package provides an
implementation of @dfn{multivariate curve resolution alternating least
squares} (MCR-ALS).

Commonly applied constraints include unimodality, non-negativity, and
normalization of components.  Several data matrices may be decomposed
simultaneously by assuming that one of the two matrices in the bilinear
decomposition is shared between datasets.")
    (license license:gpl2+)))

(define-public r-strucchange
  (package
    (name "r-strucchange")
    (version "1.5-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "strucchange" version))
       (sha256
        (base32
         "1y022363a4pp0mnji91sjh1qiyspkh09sybqwj03r9pmwrd7q93x"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-sandwich" ,r-sandwich)
       ("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/strucchange")
    (synopsis "Testing, monitoring, and dating structural changes")
    (description
     "This package provides tools for testing, monitoring and dating
structural changes in (linear) regression models.  It features tests/methods
from the generalized fluctuation test framework as well as from the F
test (Chow test) framework.  This includes methods to fit, plot and test
fluctuation processes (e.g., CUSUM, MOSUM, recursive/moving estimates) and F
statistics, respectively.  It is possible to monitor incoming data online
using fluctuation processes.  Finally, the breakpoints in regression models
with structural changes can be estimated together with confidence intervals.
Emphasis is always given to methods for visualizing the data.")
    ;; Either of these two GPL versions
    (license (list license:gpl2 license:gpl3))))

(define-public r-pixmap
  (package
    (name "r-pixmap")
    (version "0.4-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pixmap" version))
       (sha256
        (base32
         "04klxp6jndw1bp6z40v20fbmdmdpfca2g0czmmmgbkark9s1183g"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/pixmap")
    (synopsis "Tools for bitmap images")
    (description
     "This package provides functions for importing, exporting, plotting and
other manipulations of bitmapped images.")
    (license license:gpl2)))

(define-public r-rapidjsonr
  (package
    (name "r-rapidjsonr")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rapidjsonr" version))
       (sha256
        (base32
         "07zdirhbzmvq3cp4xn8ngk1lgxbbabzays315zxbs3sxrz6lzjb2"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rapidjsonr")
    (synopsis "JSON parser")
    (description
     "This package provides JSON parsing capability through the Rapidjson
library.")
    (license license:expat)))

(define-public r-ontologyindex
  (package
    (name "r-ontologyindex")
    (version "2.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ontologyIndex" version))
       (sha256
        (base32
         "127hlf0z5fmbgnq4p9h8nvn6p72d2fpcn846zzb99s213421jnry"))))
    (properties `((upstream-name . "ontologyIndex")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ontologyIndex")
    (synopsis "Functions for processing ontologies in R")
    (description
     "This package provides functions for reading ontologies into R as lists
and manipulating sets of ontological terms.")
    (license license:gpl2+)))

(define-public r-gargle
  (package
    (name "r-gargle")
    (version "0.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gargle" version))
       (sha256
        (base32
         "08zhfk2sl342w35i5n2c93ayypg3z0kbl0020l3y9adqka1vazgx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fs" ,r-fs)
       ("r-glue" ,r-glue)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-rlang" ,r-rlang)
       ("r-withr" ,r-withr)))
    (home-page "https://gargle.r-lib.org")
    (synopsis "Utilities for working with Google APIs")
    (description
     "This package provides utilities for working with Google APIs.  This
includes functions and classes for handling common credential types and for
preparing, executing, and processing HTTP requests.")
    (license license:expat)))

(define-public r-bigrquery
  (package
    (name "r-bigrquery")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bigrquery" version))
       (sha256
        (base32
         "1ggh2gngr5x0g6y7d55y6kvn94anf7qi1bkc28cjmw61hxjq38fb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-bit64" ,r-bit64)
       ("r-curl" ,r-curl)
       ("r-dbi" ,r-dbi)
       ("r-gargle" ,r-gargle)
       ("r-glue" ,r-glue)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-prettyunits" ,r-prettyunits)
       ("r-progress" ,r-progress)
       ("r-rapidjsonr" ,r-rapidjsonr)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/rstats-db/bigrquery")
    (synopsis "R interface to Google's BigQuery API")
    (description
     "This package provides an R interface to Google's BigQuery database.")
    (license license:gpl3)))

(define-public r-gmp
  (package
    (name "r-gmp")
    (version "0.5-13.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gmp" version))
       (sha256
        (base32
         "0j2sz2nw41y9306rl1b8hbn0spz7453z5iawcq0bvslyrhc1d9ir"))))
    (build-system r-build-system)
    (arguments
     '(#:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'set-CC
           (lambda _ (setenv "CC" "gcc") #t)))))
    (inputs `(("gmp" ,gmp)))
    (home-page "https://cran.r-project.org/web/packages/gmp")
    (synopsis "Multiple precision arithmetic")
    (description
     "This package supports multiple precision arithmetic (big integers and
rationals, prime number tests, matrix computation), \"arithmetic without
limitations\" using the GNU Multiple Precision library.")
    ;; Any version of the GPL.
    (license license:gpl3+)))

(define-public r-rmpfr
  (package
    (name "r-rmpfr")
    (version "0.8-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rmpfr" version))
       (sha256
        (base32
         "09kw7hyca8xc09r2d88qj81cclar8acaq5q9q5rw9f49iffda0rr"))))
    (properties `((upstream-name . "Rmpfr")))
    (build-system r-build-system)
    (inputs
     `(("mpfr" ,mpfr)
       ("gmp" ,gmp)))
    (propagated-inputs
     `(("r-gmp" ,r-gmp)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "http://rmpfr.r-forge.r-project.org/")
    (synopsis "R bindings to the MPFR library")
    (description
     "This package supports arithmetic (via S4 classes and methods) for
arbitrary precision floating point numbers, including transcendental
functions.  To this end, the package interfaces with the @dfn{Multiple
Precision Floating-Point Reliable} (MPFR) library.")
    (license license:gpl2+)))

(define-public r-assertive-base
  (package
    (name "r-assertive-base")
    (version "0.0-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.base" version))
       (sha256
        (base32
         "1xs3ysvj0z57c58jw57pckq2rynia6ks4rmjmc02alczhk54wbgh"))))
    (properties
     `((upstream-name . "assertive.base")))
    (build-system r-build-system)
    (home-page "https://bitbucket.org/richierocks/assertive.base")
    (synopsis "Core of the assertive package")
    (description
     "This package provides a minimal set of predicates and assertions used by
the assertive package.  This is mainly for use by other package developers who
want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-properties
  (package
    (name "r-assertive-properties")
    (version "0.0-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.properties" version))
       (sha256
        (base32
         "0sqs54acs9qk9kvm32rxzfbzxz1l8mjahpfnw7r30z2brgz661jw"))))
    (properties
     `((upstream-name . "assertive.properties")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.properties")
    (synopsis "Assertions to check properties of variables")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of variables, such as length, names and attributes.  This is
mainly for use by other package developers who want to include run-time
testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-numbers
  (package
    (name "r-assertive-numbers")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.numbers" version))
       (sha256
        (base32
         "0jc3ss64j4m7bjydhagwwmka5n7c72vpw4kfcch0m5jvkq5qrqds"))))
    (properties
     `((upstream-name . "assertive.numbers")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.numbers")
    (synopsis "Assertions to check properties of numbers")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of numbers.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-sets
  (package
    (name "r-assertive-sets")
    (version "0.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.sets" version))
       (sha256
        (base32
         "1cqvh2syvh5b6d85h601zjmsdbbf3h8q98ids4dfl4frdshpasc7"))))
    (properties
     `((upstream-name . "assertive.sets")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.sets")
    (synopsis "Assertions to check properties of sets")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of sets.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-matrices
  (package
    (name "r-assertive-matrices")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.matrices" version))
       (sha256
        (base32
         "16sykzcndv6y2d43x6v9n7m95kv76364h39kh10w4z0xw6ksfqil"))))
    (properties
     `((upstream-name . "assertive.matrices")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.matrices")
    (synopsis "Assertions to check properties of matrices")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of matrices.  This is mainly for use by other package
developers who want to include run-time testing features in their own
packages.")
    (license license:gpl3+)))

(define-public r-assertive-models
  (package
    (name "r-assertive-models")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.models" version))
       (sha256
        (base32
         "0bn4j4v5qvb2d672cgri61p8d9v258pmz35y3lvm6b9mdxwdi9mr"))))
    (properties
     `((upstream-name . "assertive.models")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.models")
    (synopsis "Assertions to check properties of models")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of models.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-reflection
  (package
    (name "r-assertive-reflection")
    (version "0.0-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.reflection" version))
       (sha256
        (base32
         "19zmsbn00crfqm0kwd9ys5gv87xs3gi6wmlikrz9xiwzm7hp4dhj"))))
    (properties
     `((upstream-name . "assertive.reflection")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.reflection")
    (synopsis "Assertions for checking the state of R")
    (description
     "This package provides a set of predicates and assertions for checking
the state and capabilities of R, the operating system it is running on, and
the IDE being used.  This is mainly for use by other package developers who
want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-types
  (package
    (name "r-assertive-types")
    (version "0.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.types" version))
       (sha256
        (base32
         "0zxq1jfrzgw95ll7alvm0xnk7aihjdksngq4ya2whyvfjbmv4vdb"))))
    (properties
     `((upstream-name . "assertive.types")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-properties" ,r-assertive-properties)
       ("r-codetools" ,r-codetools)))
    (home-page "https://bitbucket.org/richierocks/assertive.types")
    (synopsis "Assertions to check types of variables")
    (description
     "This package provides a set of predicates and assertions for checking
the types of variables.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-files
  (package
    (name "r-assertive-files")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.files" version))
       (sha256
        (base32
         "02pfz8j5vwcj5kl6zca46894li7lxwnlrr29j922f14ay6kdssmy"))))
    (properties
     `((upstream-name . "assertive.files")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-numbers" ,r-assertive-numbers)))
    (home-page "https://bitbucket.org/richierocks/assertive.files")
    (synopsis "Assertions to check properties of files")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of files and connections.  This is mainly for use by other
package developers who want to include run-time testing features in their own
packages.")
    (license license:gpl3+)))

(define-public r-assertive-code
  (package
    (name "r-assertive-code")
    (version "0.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.code" version))
       (sha256
        (base32
         "1qhbp668zfvhqs8avkhg9amp4zyazz6dsy4fc6kpdmw3sv8yi07g"))))
    (properties
     `((upstream-name . "assertive.code")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-properties" ,r-assertive-properties)
       ("r-assertive-types" ,r-assertive-types)))
    (home-page "https://bitbucket.org/richierocks/assertive.code")
    (synopsis "Assertions to check properties of code")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of code.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-datetimes
  (package
    (name "r-assertive-datetimes")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.datetimes" version))
       (sha256
        (base32
         "00a98fx8p3pr3ckayh8wmxmm4rz01s67wah9697m92yci6pv3m78"))))
    (properties
     `((upstream-name . "assertive.datetimes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-types" ,r-assertive-types)))
    (home-page "https://bitbucket.org/richierocks/assertive.datetimes")
    (synopsis "Assertions to check properties of dates and times")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of dates and times.  This is mainly for use by other package
developers who want to include run-time testing features in their own
packages.")
    (license license:gpl3+)))

(define-public r-assertive-strings
  (package
    (name "r-assertive-strings")
    (version "0.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.strings" version))
       (sha256
        (base32
         "0n6jrk88670g4ym0r8ii40a08a90z1xadj8wcryk8h0nl04dchfm"))))
    (properties
     `((upstream-name . "assertive.strings")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-types" ,r-assertive-types)
       ("r-stringi" ,r-stringi)))
    (home-page "https://bitbucket.org/richierocks/assertive.strings")
    (synopsis "Assertions to check properties of strings")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of strings.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-data-us
  (package
    (name "r-assertive-data-us")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.data.us" version))
       (sha256
        (base32
         "1bgspn0sccmp9z7s7djvdvprgxlyc5vrxznp4zfjb79kwvgn83hq"))))
    (properties
     `((upstream-name . "assertive.data.us")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-strings" ,r-assertive-strings)))
    (home-page "https://bitbucket.org/richierocks/assertive.data.us")
    (synopsis "Assertions to check properties of strings")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of US-specific complex data types.  This is mainly for use by
other package developers who want to include run-time testing features in
their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-data-uk
  (package
    (name "r-assertive-data-uk")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.data.uk" version))
       (sha256
        (base32
         "1fzjvhwp7mwkqqix29khvs6zcrc82n6j4czvzzb473vyjyvdlj5b"))))
    (properties
     `((upstream-name . "assertive.data.uk")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-strings" ,r-assertive-strings)))
    (home-page "https://bitbucket.org/richierocks/assertive.data.uk")
    (synopsis "Assertions to check properties of strings")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of UK-specific complex data types.  This is mainly for use by
other package developers who want to include run-time testing features in
their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-data
  (package
    (name "r-assertive-data")
    (version "0.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.data" version))
       (sha256
        (base32
         "00cvg2g36mdl8plrzx40m63qd55742mddqrchwy9n3c7mm4gn02s"))))
    (properties
     `((upstream-name . "assertive.data")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-strings" ,r-assertive-strings)))
    (home-page "https://bitbucket.org/richierocks/assertive.data")
    (synopsis "Assertions to check properties of data")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of (country independent) complex data types.  This is mainly
for use by other package developers who want to include run-time testing
features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive
  (package
    (name "r-assertive")
    (version "0.3-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive" version))
       (sha256
        (base32
         "0blbbhlxcb5ffdxqxi62xs33ljiawh6s22a0pyvbbh79jf46rzr3"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-code" ,r-assertive-code)
       ("r-assertive-data" ,r-assertive-data)
       ("r-assertive-data-uk" ,r-assertive-data-uk)
       ("r-assertive-data-us" ,r-assertive-data-us)
       ("r-assertive-datetimes" ,r-assertive-datetimes)
       ("r-assertive-files" ,r-assertive-files)
       ("r-assertive-matrices" ,r-assertive-matrices)
       ("r-assertive-models" ,r-assertive-models)
       ("r-assertive-numbers" ,r-assertive-numbers)
       ("r-assertive-properties" ,r-assertive-properties)
       ("r-assertive-reflection" ,r-assertive-reflection)
       ("r-assertive-sets" ,r-assertive-sets)
       ("r-assertive-strings" ,r-assertive-strings)
       ("r-assertive-types" ,r-assertive-types)
       ("r-knitr" ,r-knitr)))
    (home-page "https://bitbucket.org/richierocks/assertive")
    (synopsis "Readable check functions to ensure code integrity")
    (description
     "This package provides lots of predicates (@code{is_*} functions) to
check the state of your variables, and assertions (@code{assert_*} functions)
to throw errors if they aren't in the right form.")
    (license license:gpl3+)))

(define-public r-dotcall64
  (package
    (name "r-dotcall64")
    (version "1.0-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dotCall64" version))
       (sha256
        (base32
         "1b8p7m3w0m7bp977c6jz74xkd611cxg11j49yza59k5fp338scb9"))))
    (properties `((upstream-name . "dotCall64")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://git.math.uzh.ch/reinhard.furrer/dotCall64")
    (synopsis "Enhanced foreign function interface supporting long vectors")
    (description
     "This package provides @code{.C64()}, an enhanced version of @code{.C()}
and @code{.Fortran()} from the R foreign function interface.  @code{.C64()}
supports long vectors, arguments of type 64-bit integer, and provides a
mechanism to avoid unnecessary copies of read-only and write-only arguments.
This makes it a convenient and fast interface to C/C++ and Fortran code.")
    (license license:gpl2+)))

(define-public r-spam
  (package
    (name "r-spam")
    (version "2.5-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "spam" version))
       (sha256
        (base32 "0ry0a76cljlmilrzcriiizcidxyhq1i7i9bqhvl1qda81ld8hifi"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dotcall64" ,r-dotcall64)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://www.math.uzh.ch/pages/spam/")
    (synopsis "Sparse matrix algebra")
    (description
     "This package provides a set of functions for sparse matrix algebra.
Differences with other sparse matrix packages are:

@enumerate
@item it only supports (essentially) one sparse matrix format;
@item it is based on transparent and simple structure(s);
@item it is tailored for MCMC calculations within G(M)RF;
@item and it is fast and scalable (with the extension package @code{spam64}).
@end enumerate\n")
    ;; Either of these licenses
    (license (list license:bsd-3 license:lgpl2.0))))

(define-public r-fields
  (package
    (name "r-fields")
    (version "10.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fields" version))
       (sha256
        (base32 "12k97vfjlz5h8vynirnvik1nyj1iw25n8xl7awmx9mpd6wvgy2s9"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-maps" ,r-maps)
       ("r-spam" ,r-spam)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://www.image.ucar.edu/fields")
    (synopsis "Tools for spatial data")
    (description
     "This is a package for curve, surface and function fitting with an
emphasis on splines, spatial data and spatial statistics.  The major methods
include cubic, and thin plate splines, Kriging, and compactly supported
covariance functions for large data sets.")
    (license license:gpl2+)))

(define-public r-spatialextremes
  (package
    (name "r-spatialextremes")
    (version "2.0-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SpatialExtremes" version))
       (sha256
        (base32
         "0r2byz5xxc46zqnigdax28q7446ibmzmsmi10lmm2hdks3ml6sl3"))))
    (properties
     `((upstream-name . "SpatialExtremes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fields" ,r-fields)
       ("r-maps" ,r-maps)))
    (home-page "http://spatialextremes.r-forge.r-project.org/")
    (synopsis "Modelling spatial extremes")
    (description
     "This package provides tools for the statistical modelling of spatial
extremes using max-stable processes, copula or Bayesian hierarchical models.
More precisely, this package allows (conditional) simulations from various
parametric max-stable models, analysis of the extremal spatial dependence, the
fitting of such processes using composite likelihoods or least square (simple
max-stable processes only), model checking and selection and prediction.")
    (license license:gpl2+)))

(define-public r-drc
  (package
    (name "r-drc")
    (version "3.0-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "drc" version))
       (sha256
        (base32
         "0c8xn8ripzq270hy8d16fcnx02l02alddznd7fqwk3jyi6113h1y"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-car" ,r-car)
       ("r-gtools" ,r-gtools)
       ("r-mass" ,r-mass)
       ("r-multcomp" ,r-multcomp)
       ("r-plotrix" ,r-plotrix)
       ("r-scales" ,r-scales)))
    (home-page "https://cran.r-project.org/web/packages/drc")
    (synopsis "Analysis of dose-response curves")
    (description
     "This package provides a suite of flexible and versatile model fitting
and after-fitting functions for the analysis of dose-response data.")
    (license license:gpl2+)))

(define-public r-rmeta
  (package
    (name "r-rmeta")
    (version "3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rmeta" version))
       (sha256
        (base32
         "0vkbnxp579v8zmcv1isdbzj5swpr6fq17zwparxcvzswjc2x9ydr"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rmeta")
    (synopsis "Tools for meta-analysis")
    (description
     "This package provides functions for simple fixed and random effects
meta-analysis for two-sample comparisons and cumulative meta-analyses.  It
draws standard summary plots, funnel plots, and computes summaries and tests
for association and heterogeneity.")
    (license license:gpl2)))

(define-public r-bootstrap
  (package
    (name "r-bootstrap")
    (version "2019.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bootstrap" version))
       (sha256
        (base32
         "1546jqhhw5h177ii8jkdikyd26rv6gwkav816np1zks4p7zgsljj"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/bootstrap")
    (synopsis "Functions for the book \"An Introduction to the Bootstrap\"")
    (description
     "This package provides software and data for the book \"An Introduction
to the Bootstrap\" by B. Efron and R. Tibshirani, 1993, Chapman and Hall.
This package is primarily provided for projects already based on it, and for
support of the book.  New projects should preferentially use the recommended
package \"boot\".")
    (license license:bsd-3)))

(define-public r-survivalroc
  (package
    (name "r-survivalroc")
    (version "1.0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "survivalROC" version))
       (sha256
        (base32
         "0wnd65ff5w679hxa1zrpfrx9qg47q21pjxppsga6m3h4iq1yfj8l"))))
    (properties `((upstream-name . "survivalROC")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/survivalROC")
    (synopsis "Time-dependent ROC curve estimation from censored survival data")
    (description
     "Compute time-dependent ROC curve from censored survival data using
Kaplan-Meier (KM) or Nearest Neighbor Estimation (NNE) method of Heagerty,
Lumley & Pepe (Biometrics, Vol 56 No 2, 2000, PP 337-344)")
    (license license:gpl2+)))

(define-public r-longitudinal
  (package
    (name "r-longitudinal")
    (version "1.1.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "longitudinal" version))
       (sha256
        (base32
         "1d83ws28nxi3kw5lgd5n5y7865djq7ky72fw3ddi1fkkhg1r9y6l"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-corpcor" ,r-corpcor)))
    (home-page "http://strimmerlab.org/software/longitudinal/")
    (synopsis "Analysis of multiple time course data")
    (description
     "This package contains general data structures and functions for
longitudinal data with multiple variables, repeated measurements, and
irregularly spaced time points.  It also implements a shrinkage estimator of
dynamical correlation and dynamical covariance.")
    (license license:gpl3+)))

(define-public r-genenet
  (package
    (name "r-genenet")
    (version "1.2.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GeneNet" version))
       (sha256
        (base32
         "0cdhrj15rz0w0pyw3r8mikrzsdh95y5i1c0pa3cn0c2bjnjx3x3n"))))
    (properties `((upstream-name . "GeneNet")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-corpcor" ,r-corpcor)
       ("r-fdrtool" ,r-fdrtool)
       ("r-longitudinal" ,r-longitudinal)))
    (home-page "http://strimmerlab.org/software/genenet/")
    (synopsis "Modeling and inferring gene networks")
    (description
     "This package analyzes gene expression (time series) data with focus on
the inference of gene networks.  In particular, GeneNet implements the methods
of Schaefer and Strimmer (2005a,b,c) and Opgen-Rhein and Strimmer (2006, 2007)
for learning large-scale gene association networks (including assignment of
putative directions).")
    (license license:gpl3+)))

(define-public r-rbamtools
  (package
    (name "r-rbamtools")
    (version "2.16.17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rbamtools" version))
       (sha256
        (base32
         "0qj37ljdva3v29s01dkrbg31mcfzy3bl145cp40d54v4h9xhcghc"))))
    (build-system r-build-system)
    (inputs `(("zlib" ,zlib)))
    (propagated-inputs
     `(("r-refgenome" ,r-refgenome)))
    (home-page "https://cran.r-project.org/web/packages/rbamtools")
    (synopsis "Read and write BAM (binary alignment) files")
    (description
     "This package provides an R interface to functions of the SAMtools
library.")
    (license license:artistic2.0)))

(define-public r-protviz
  (package
    (name "r-protviz")
    (version "0.6.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "protViz" version))
       (sha256
        (base32
         "1ldciqh3f43xr9663yyhd9r6qwrg4c4vmkprlcancbnd460wakg7"))))
    (properties `((upstream-name . "protViz")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/protViz/protViz/")
    (synopsis "Visualizing and analyzing mass spectrometry data in proteomics")
    (description
     "This package helps with quality checks, visualizations and analysis of
mass spectrometry data, coming from proteomics experiments.  The package is
developed, tested and used at the Functional Genomics Center Zurich, where it
is used mainly for prototyping, teaching, and having fun with proteomics data.
But it can also be used to do data analysis for small scale data sets.")
    (license license:gpl3)))

(define-public r-cmprsk
  (package
    (name "r-cmprsk")
    (version "2.2-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cmprsk" version))
       (sha256
        (base32 "0xhgfg5b4i9skkaxp7gzkafgg5bqs5q1rp4hpw2jjmykg2nifn99"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-survival" ,r-survival)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/cmprsk")
    (synopsis "Subdistribution analysis of competing risks")
    (description
     "This package provides tool for estimation, testing and regression
modeling of subdistribution functions in competing risks, as described in
Gray (1988), A class of K-sample tests for comparing the cumulative incidence
of a competing risk, Ann. Stat. 16:1141-1154, and Fine JP and Gray RJ (1999),
A proportional hazards model for the subdistribution of a competing risk,
JASA, 94:496-509.")
    (license license:gpl2+)))

(define-public r-etm
  (package
    (name "r-etm")
    (version "1.0.5.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "etm" version))
       (sha256
        (base32
         "0m41pm277sd50pharigcqzr1a2g92wnmdf6fcab6fx16ia2fzrm7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-lattice" ,r-lattice)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/etm")
    (synopsis "Empirical transition matrix")
    (description
     "The @dfn{empirical transition matrix} (etm) package permits to estimate
the matrix of transition probabilities for any time-inhomogeneous multistate
model with finite state space using the Aalen-Johansen estimator.")
    (license license:expat)))

(define-public r-epi
  (package
    (name "r-epi")
    (version "2.40")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Epi" version))
       (sha256
        (base32
         "046y10vwks5y84pzccmrn6d4pd6qz70imvp1hw5ywp8fnwzfh4g5"))))
    (properties `((upstream-name . "Epi")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cmprsk" ,r-cmprsk)
       ("r-data-table" ,r-data-table)
       ("r-etm" ,r-etm)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-mgcv" ,r-mgcv)
       ("r-numderiv" ,r-numderiv)
       ("r-plyr" ,r-plyr)
       ("r-survival" ,r-survival)
       ("r-zoo" ,r-zoo)))
    (home-page "https://BendixCarstensen.com/Epi/")
    (synopsis "Statistical analysis in epidemiology")
    (description
     "This package provides functions for demographic and epidemiological
analysis in the Lexis diagram, i.e. register and cohort follow-up data, in
particular representation, manipulation and simulation of multistate data -
the Lexis suite of functions, which includes interfaces to the @code{mstate},
@code{etm} and @code{cmprsk} packages.  It also contains functions for
Age-Period-Cohort and Lee-Carter modeling and a function for interval censored
data and some useful functions for tabulation and plotting, as well as a
number of epidemiological data sets.")
    (license license:gpl2)))

(define-public r-ppls
  (package
    (name "r-ppls")
    (version "1.6-1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ppls" version))
       (sha256
        (base32
         "1zyrisy3c4cz896j1bjh61sf57wdl9p8ywdq268cl819szfq78mx"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ppls")
    (synopsis "Penalized partial least squares")
    (description
     "This package contains linear and nonlinear regression methods based on
partial least squares and penalization techniques.  Model parameters are
selected via cross-validation, and confidence intervals ans tests for the
regression coefficients can be conducted via jackknifing.")
    (license license:gpl2+)))

(define-public r-huge
  (package
    (name "r-huge")
    (version "1.3.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "huge" version))
       (sha256
        (base32 "07n3j1va2z4v30rj22cww72khgzbz2xsp0yc0qswlrwyxi4my5i3"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "https://cran.r-project.org/web/packages/huge")
    (synopsis "High-dimensional undirected graph estimation")
    (description
     "This package provides a general framework for high-dimensional
undirected graph estimation.  It integrates data preprocessing, neighborhood
screening, graph estimation, and model selection techniques into a pipeline.")
    (license license:gpl2)))

(define-public r-parcor
  (package
    (name "r-parcor")
    (version "0.2-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "parcor" version))
       (sha256
        (base32
         "0vgs6k92vdr0cmb8cwbv2ff6qavw30agskfd8bfh17hsskrisvx0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-epi" ,r-epi)
       ("r-genenet" ,r-genenet)
       ("r-glmnet" ,r-glmnet)
       ("r-mass" ,r-mass)
       ("r-ppls" ,r-ppls)))
    (home-page "https://cran.r-project.org/web/packages/parcor")
    (synopsis "Regularized estimation of partial correlation matrices")
    (description
     "This package estimates the matrix of partial correlations based on
different regularized regression methods: lasso, adaptive lasso, PLS, and
Ridge Regression.  In addition, the package provides model selection for
lasso, adaptive lasso and Ridge regression based on cross-validation.")
    (license license:gpl2+)))

(define-public r-mcmc
  (package
    (name "r-mcmc")
    (version "0.9-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mcmc" version))
       (sha256
        (base32
         "0q42m8ab7b6bxhns494ksjdss5f3c5m2jjfdlfj6fk1nz7ax7i5p"))))
    (build-system r-build-system)
    (home-page "https://www.stat.umn.edu/geyer/mcmc/")
    (synopsis "Markov chain Monte Carlo")
    (description
     "This package simulates continuous distributions of random vectors using
@dfn{Markov chain Monte Carlo} (MCMC).  Users specify the distribution by an R
function that evaluates the log unnormalized density.  Algorithms are random
walk Metropolis algorithm (function @code{metrop}), simulated
tempering (function @code{temper}), and morphometric random walk
Metropolis (function @code{morph.metrop}), which achieves geometric ergodicity
by change of variable.")
    (license license:expat)))

(define-public r-listenv
  (package
    (name "r-listenv")
    (version "0.8.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "listenv" version))
       (sha256
        (base32
         "0ps8bk7zlhbviawrw7vw25skjq81hkk3ijyi6g74dmfqy8zsyapx"))))
    (build-system r-build-system)
    (native-inputs
     `(("r-r-rsp" ,r-r-rsp))) ; vignette builder
    (home-page "https://github.com/HenrikBengtsson/listenv")
    (synopsis "Environments behaving (almost) as lists")
    (description
     "This package implements list environments.  List environments are
environments that have list-like properties.  For instance, the elements of a
list environment are ordered and can be accessed and iterated over using index
subsetting.")
    (license license:lgpl2.1+)))

(define-public r-globals
  (package
    (name "r-globals")
    (version "0.12.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "globals" version))
       (sha256
        (base32
         "1ha8iasgijp4q3v2b0b17y1wh7cd3nvzd9b03w49qm2bidkaf68m"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-codetools" ,r-codetools)))
    (home-page "https://github.com/HenrikBengtsson/globals")
    (synopsis "Identify global objects in R expressions")
    (description
     "This package provides tools to identify global (\"unknown\" or \"free\")
objects in R expressions by code inspection using various strategies, e.g.
conservative or liberal.  The objective of this package is to make it as
simple as possible to identify global objects for the purpose of exporting
them in distributed compute environments.")
    (license license:lgpl2.1+)))

(define-public r-future
  (package
    (name "r-future")
    (version "1.16.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "future" version))
       (sha256
        (base32
         "1xaqh0b2knf5bp23mc0kriq0iqhqna31q3b7d960piqjhzrb03dm"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-globals" ,r-globals)
       ("r-listenv" ,r-listenv)))
    (native-inputs
     `(("r-r-rsp" ,r-r-rsp))) ; vignette builder
    (home-page "https://github.com/HenrikBengtsson/future")
    (synopsis "Unified parallel and distributed processing in R")
    (description
     "The purpose of this package is to provide a lightweight and unified
Future API for sequential and parallel processing of R expression via futures.
This package implements sequential, multicore, multisession, and cluster
futures.  With these, R expressions can be evaluated on the local machine, in
parallel a set of local machines, or distributed on a mix of local and remote
machines.  Extensions to this package implement additional backends for
processing futures via compute cluster schedulers etc.  Because of its unified
API, there is no need to modify any code in order to switch from sequential on
the local machine to, say, distributed processing on a remote compute cluster.")
    (license license:lgpl2.1+)))

(define-public r-future-apply
  (package
    (name "r-future-apply")
    (version "1.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "future.apply" version))
       (sha256
        (base32
         "1kgq6dv96hdy35kysqkn606nj7s9dp4ibgpm6n46gqhc5n75lzkk"))))
    (properties `((upstream-name . "future.apply")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-future" ,r-future)
       ("r-globals" ,r-globals)))
    (native-inputs
     `(("r-r-rsp" ,r-r-rsp))) ; vignette builder
    (home-page "https://github.com/HenrikBengtsson/future.apply")
    (synopsis "Apply function to elements in parallel using futures")
    (description
     "This package provides implementations of @code{apply()},
@code{eapply()}, @code{lapply()}, @code{Map()}, @code{mapply()},
@code{replicate()}, @code{sapply()}, @code{tapply()}, and @code{vapply()} that
can be resolved using any future-supported backend, e.g. parallel on the local
machine or distributed on a compute cluster.")
    (license license:gpl2+)))

(define-public r-rsvd
  (package
    (name "r-rsvd")
    (version "1.0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rsvd" version))
       (sha256
        (base32
         "1fvrw46fl5xb2akaa4mp8nja4h7nn4bdhnjdrk22fsdfqc7hwmhk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)))
    (home-page "https://github.com/erichson/rSVD")
    (synopsis "Randomized singular value decomposition")
    (description
     "Low-rank matrix decompositions are fundamental tools and widely used for
data analysis, dimension reduction, and data compression.  Classically, highly
accurate deterministic matrix algorithms are used for this task.  However, the
emergence of large-scale data has severely challenged our computational
ability to analyze big data.  The concept of randomness has been demonstrated
as an effective strategy to quickly produce approximate answers to familiar
problems such as the @dfn{singular value decomposition} (SVD).  This package
provides several randomized matrix algorithms such as the randomized singular
value decomposition (@code{rsvd}), randomized principal component
analysis (@code{rpca}), randomized robust principal component
analysis (@code{rrpca}), randomized interpolative decomposition (@code{rid}),
and the randomized CUR decomposition (@code{rcur}).  In addition several plot
functions are provided.")
    (license license:gpl3+)))

(define-public r-sloop
  (package
    (name "r-sloop")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sloop" version))
       (sha256
        (base32
         "00fk5fr5zsk2qxc1kfhmshhjxgnamm3401089sx8m2l529zd6r8j"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-codetools" ,r-codetools)
       ("r-crayon" ,r-crayon)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/r-lib/sloop")
    (synopsis "Helpers for object-oriented programming in R")
    (description
     "This package provides a collection of helper functions designed to
help you to better understand object oriented programming in R, particularly
using @code{S3}.")
    (license license:gpl3)))

(define-public r-capushe
  (package
    (name "r-capushe")
    (version "1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "capushe" version))
       (sha256
        (base32
         "1aa76ir1kp67hiz7dr60azyc71yzslshyc640fjh0fpw0sp5kwbc"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/capushe/index.html")
    (synopsis "Calibrating penalties using slope heuristics")
    (description
     "This package provides tools for the calibration of penalized criteria
for model selection.  The calibration methods available are based on the slope
heuristics.")
    (license license:gpl2+)))

(define-public r-dorng
  (package
    (name "r-dorng")
    (version "1.8.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "doRNG" version))
       (sha256
        (base32
         "1jff27zzrvd1fd61x2m9468h8xn3s1c9f6wibviy5zdhj5dx9s9k"))))
    (properties `((upstream-name . "doRNG")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-foreach" ,r-foreach)
       ("r-iterators" ,r-iterators)
       ("r-rngtools" ,r-rngtools)))
    (home-page "https://renozao.github.io/doRNG/")
    (synopsis "Generic reproducible parallel backend for foreach loops")
    (description
     "This package provides functions to perform reproducible parallel
@code{foreach} loops, using independent random streams as generated by
L'Ecuyer's combined multiple-recursive generator.  It enables to easily
convert standard @code{%dopar%} loops into fully reproducible loops,
independently of the number of workers, the task scheduling strategy, or the
chosen parallel environment and associated foreach backend.")
    (license license:gpl2+)))

(define-public r-blockmodeling
  (package
    (name "r-blockmodeling")
    (version "0.3.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "blockmodeling" version))
       (sha256
        (base32
         "12paf76l3wlxad14bkxn37lw9rg6ka473m86wlcf3yhriw8kbaiz"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/blockmodeling")
    (synopsis "Generalized and classical blockmodeling of valued networks")
    (description
     "This package is primarily meant as an implementation of generalized
blockmodeling for valued networks.  In addition, measures of similarity or
dissimilarity based on structural equivalence and regular equivalence (REGE
algorithms) can be computed and partitioned matrices can be plotted.")
    (license license:gpl2+)))

(define-public r-upsetr
  (package
    (name "r-upsetr")
    (version "1.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "UpSetR" version))
       (sha256
        (base32
         "007i0njnjjy7vbrxabwav7a1kk2n0hn2mkvqsdzzfk10ckp5y7im"))))
    (properties `((upstream-name . "UpSetR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-plyr" ,r-plyr)
       ("r-scales" ,r-scales)))
    (home-page "https://github.com/hms-dbmi/UpSetR")
    (synopsis "Visualize intersecting sets")
    (description
     "This package provides a more scalable alternative to Venn and Euler
diagrams for visualizing intersecting sets.  Create visualizations of
intersecting sets using a novel matrix design, along with visualizations of
several common set, element and attribute related tasks.")
    (license license:expat)))

;; This package includes a JavaScript file, which is not minified.  When
;; upgrading please check that there are no new minified JavaScript files.
(define-public r-shinybs
  (package
    (name "r-shinybs")
    (version "0.61")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinyBS" version))
       (sha256
        (base32
         "0rhim4mbp4x9vvm7xkmpl7mhb9qd1gr96cr4dv330v863ra2kgji"))))
    (properties `((upstream-name . "shinyBS")))
    (build-system r-build-system)
    ;; The tests spawn Shiny browser apps.  They cannot be run
    ;; non-interactively.
    (arguments '(#:tests? #f))
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-shiny" ,r-shiny)))
    (home-page "https://ebailey78.github.io/shinyBS/")
    (synopsis "Twitter Bootstrap components for Shiny")
    (description
     "This package adds additional Twitter Bootstrap components to Shiny.")
    (license license:gpl3)))

(define-public r-outliers
  (package
    (name "r-outliers")
    (version "0.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "outliers" version))
       (sha256
        (base32
         "0vcqfqmmv4yblyp3s6bd25r49pxb7hjzipiic5a82924nqfqzkmn"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/outliers/index.html")
    (synopsis "Tests for outliers")
    (description
     "This package provides a collection of some tests commonly used for
identifying outliers.")
    (license license:gpl2+)))

(define-public r-bayesm
  (package
    (name "r-bayesm")
    (version "3.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bayesm" version))
       (sha256
        (base32 "154glks7rsjkza0sfi1kj7wj727py9sl1ba6sswflwmwc9n226q6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "http://www.perossi.org/home/bsm-1")
    (synopsis "Bayesian inference for marketing/micro-econometrics")
    (description
     "This package covers many important models used in marketing and
micro-econometrics applications, including Bayes Regression (univariate or
multivariate dep var), Bayes Seemingly Unrelated Regression (SUR), Binary and
Ordinal Probit, Multinomial Logit (MNL) and Multinomial Probit (MNP),
Multivariate Probit, Negative Binomial (Poisson) Regression, Multivariate
Mixtures of Normals (including clustering), Dirichlet Process Prior Density
Estimation with normal base, Hierarchical Linear Models with normal prior and
covariates, Hierarchical Linear Models with a mixture of normals prior and
covariates, Hierarchical Multinomial Logits with a mixture of normals prior
and covariates, Hierarchical Multinomial Logits with a Dirichlet Process prior
and covariates, Hierarchical Negative Binomial Regression Models, Bayesian
analysis of choice-based conjoint data, Bayesian treatment of linear
instrumental variables models, Analysis of Multivariate Ordinal survey data
with scale usage heterogeneity, and Bayesian Analysis of Aggregate Random
Coefficient Logit Models.")
    (license license:gpl2+)))

(define-public r-tensora
  (package
    (name "r-tensora")
    (version "0.36.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tensorA" version))
       (sha256
        (base32
         "176hjy3bvg3in62r97wxbhq187sjz6c1gwy9x6spaxl6k4my3zy7"))))
    (properties `((upstream-name . "tensorA")))
    (build-system r-build-system)
    (home-page "http://www.stat.boogaart.de/tensorA")
    (synopsis "Advanced tensor arithmetic with named indices")
    (description
     "This package provides convenience functions for advanced linear algebra
with tensors and computation with datasets of tensors on a higher level
abstraction.  It includes Einstein and Riemann summing conventions, dragging,
co- and contravariate indices, and parallel computations on sequences of
tensors.")
    (license license:gpl2+)))

(define-public r-rarpack
  (package
    (name "r-rarpack")
    (version "0.11-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rARPACK" version))
       (sha256
        (base32
         "12h2y46xcfldhjdmm960swgn9b23zvkj5vg2bi42s9qxwgi02d63"))))
    (properties `((upstream-name . "rARPACK")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rspectra" ,r-rspectra)))
    (home-page "https://github.com/yixuan/rARPACK")
    (synopsis "Solvers for large scale eigenvalue and SVD problems")
    (description
     "This package was previously an R wrapper of the ARPACK library, and now
a shell of the R package RSpectra, an R interface to the Spectra library for
solving large scale eigenvalue/vector problems.  The current version of
rARPACK simply imports and exports the functions provided by RSpectra.  New
users of rARPACK are advised to switch to the RSpectra package.")
    (license license:bsd-3)))

(define-public r-compositions
  (package
    (name "r-compositions")
    (version "1.40-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "compositions" version))
       (sha256
        (base32
         "0z40llyij3cc80ac1vzzrpykk6ysp89bn6dyyh40fbnc4anwx69a"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayesm" ,r-bayesm)
       ("r-robustbase" ,r-robustbase)
       ("r-tensora" ,r-tensora)))
    (home-page "http://www.stat.boogaart.de/compositions")
    (synopsis "Compositional data analysis")
    (description
     "This package provides functions for the consistent analysis of
compositional data (e.g. portions of substances) and positive
numbers (e.g. concentrations).")
    (license license:gpl2+)))

(define-public r-cobs
  (package
    (name "r-cobs")
    (version "1.3-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cobs" version))
       (sha256
        (base32
         "0hiw5smk6kgk0gb9840kcqkhkybl7n30s77xhjc395x09izbgix1"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quantreg" ,r-quantreg)
       ("r-sparsem" ,r-sparsem)))
    (home-page "https://cran.r-project.org/web/packages/cobs")
    (synopsis "Constrained B-Splines (sparse matrix based)")
    (description
     "This package provides qualitatively constrained (regression) smoothing
splines via linear programming and sparse matrices.")
    (license license:gpl2+)))

(define-public r-drimpute
  (package
    (name "r-drimpute")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "DrImpute" version))
       (sha256
        (base32
         "1adzarrwqb282pqgx2yqswp9rpwd1naxsmar54kddr6qyd6b923b"))))
    (properties `((upstream-name . "DrImpute")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "https://github.com/ikwak2/DrImpute")
    (synopsis "Imputing dropout events in single-cell RNA-Seq data")
    (description
     "This is an R package for imputing dropout events.  Many statistical
methods in cell type identification, visualization and lineage reconstruction
do not account for dropout events.  DrImpute can improve the performance of
such software by imputing dropout events.")
    (license license:gpl3)))

(define-public r-gamlss-dist
  (package
    (name "r-gamlss-dist")
    (version "5.1-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gamlss.dist" version))
       (sha256
        (base32 "1p904x0b07z4amaqdn2xhs7qzbq8lisr6lqc844s3pkxzmny7w1z"))))
    (properties `((upstream-name . "gamlss.dist")))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "http://www.gamlss.org/")
    (synopsis "Distributions for Generalized Additive Models for location scale and shape")
    (description
     "This package provides a set of distributions which can be used for
modelling the response variables in Generalized Additive Models for Location
Scale and Shape.  The distributions can be continuous, discrete or mixed
distributions.  Extra distributions can be created, by transforming, any
continuous distribution defined on the real line, to a distribution defined on
ranges 0 to infinity or 0 to 1, by using a @code{log} or a @code{logit}
transformation, respectively.")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

;; This package includes JavaScript files, which are not minified.  When
;; upgrading please check that there are no new minified JavaScript files.
(define-public r-shinyjs
  (package
    (name "r-shinyjs")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinyjs" version))
       (sha256
        (base32
         "14k8y313ppj23m9rhlk8jc94x6sbn3qrsnx6xrijiyv8m8dii1l9"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-shiny" ,r-shiny)))
    (home-page "https://deanattali.com/shinyjs")
    (synopsis "Improve the user experience of your Shiny apps")
    (description
     "Perform common useful JavaScript operations in Shiny apps that will
greatly improve your apps without having to know any JavaScript.  Examples
include: hiding an element, disabling an input, resetting an input back to its
original value, delaying code execution by a few seconds, and many more useful
functions for both the end user and the developer.  Shinyjs can also be used
to easily call your own custom JavaScript functions from R.")
    (license license:agpl3+)))

;; This package includes minified JavaScript files.  When upgrading please
;; check that there are no new minified JavaScript files.
(define-public r-colourpicker
  (package
    (name "r-colourpicker")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "colourpicker" version))
       (sha256
        (base32
         "0z3v2083g7kwdp21x9s2n1crfh24agpdq3yxkcdzc2awn2pwpnpi"))))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "js-salvattore")
                         "examples/colourInput/www/salvattore.min.js")
                        (,(assoc-ref inputs "js-jquery")
                         "htmlwidgets/lib/jquery/jquery.min.js")
                        ("www/shared/colourpicker/js/colourpicker.js"
                         "www/shared/colourpicker/js/colourpicker.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (delete-file target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-miniui" ,r-miniui)
       ("r-shiny" ,r-shiny)
       ("r-shinyjs" ,r-shinyjs)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("js-jquery"
        ,(origin
           (method url-fetch)
           (uri "https://code.jquery.com/jquery-3.3.1.js")
           (sha256
            (base32
             "1b8zxrp6xwzpw25apn8j4qws0f6sr7qr7h2va5h1mjyfqvn29anq"))))
       ("js-salvattore"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/rnmp/salvattore/v1.0.9/dist/salvattore.js")
           (sha256
            (base32
             "0lfrbx7l9w5x89jpc6njmd0pk7h8fpvg537vklai2vf7b1r2nnk5"))))))
    (home-page "https://github.com/daattali/colourpicker")
    (synopsis "Color picker tool for Shiny and for selecting colors in plots")
    (description
     "This package provides a color picker that can be used as an input in
Shiny apps or Rmarkdown documents.  The color picker supports alpha opacity,
custom color palettes, and many more options.  A plot color helper tool is
available as an RStudio Addin, which helps you pick colors to use in your
plots.  A more generic color picker RStudio Addin is also provided to let you
select colors to use in your R code.")
    (license license:expat)))

(define-public r-ggextra
  (package
    (name "r-ggextra")
    (version "0.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggExtra" version))
       (sha256
        (base32
         "18mbi6gblqmrsciad1d2c9ngllk6mayaqj43k40hjq9ydqnvjbgj"))))
    (properties `((upstream-name . "ggExtra")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colourpicker" ,r-colourpicker)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gtable" ,r-gtable)
       ("r-miniui" ,r-miniui)
       ("r-r6" ,r-r6)
       ("r-scales" ,r-scales)
       ("r-shiny" ,r-shiny)
       ("r-shinyjs" ,r-shinyjs)))
    (home-page "https://github.com/daattali/ggExtra")
    (synopsis "Marginal histograms for ggplot2 and other enhancements")
    (description
     "This package is a collection of functions and layers to enhance ggplot2.
The flagship function is @code{ggMarginal()}, which can be used to add
marginal histograms/boxplots/density plots to ggplot2 scatterplots.")
    (license license:expat)))

(define-public r-minpack-lm
  (package
    (name "r-minpack-lm")
    (version "1.2-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "minpack.lm" version))
       (sha256
        (base32
         "18ym2pdql5vzngc7q5gn66d153hrfrnd8ilv8yh6vd7j7sx7vjql"))))
    (properties `((upstream-name . "minpack.lm")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/minpack.lm")
    (synopsis "Levenberg-Marquardt Nonlinear Least-Squares algorithm")
    (description
     "The @code{nls.lm} function provides an R interface to @code{lmder} and
@code{lmdif} from the MINPACK library, for solving nonlinear least-squares
problems by a modification of the Levenberg-Marquardt algorithm, with support
for lower and upper parameter bounds.  The implementation can be used via
@code{nls}-like calls using the @code{nlsLM} function.")
    (license license:gpl3)))

(define-public r-moments
  (package
    (name "r-moments")
    (version "0.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "moments" version))
       (sha256
        (base32
         "0f9y58w1hxcz4bqivirx25ywlmc80gbi6dfx5cnhkpdg1pk82fra"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/moments")
    (synopsis "Moments, cumulants, skewness, kurtosis and related tests")
    (description
     "This package provides functions to calculate: moments, Pearson's
kurtosis, Geary's kurtosis and skewness; it also includes tests related to
them (Anscombe-Glynn, D'Agostino, Bonett-Seier).")
    (license license:gpl2+)))

(define-public r-msir
  (package
    (name "r-msir")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "msir" version))
       (sha256
        (base32
         "0pvc3q162vqq3k39nni732x05zzfz4y9y2zf56d83185ypszv9kb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mclust" ,r-mclust)))
    (home-page "https://cran.r-project.org/web/packages/msir")
    (synopsis "Model-based sliced inverse regression")
    (description
     "This is an R package for dimension reduction based on finite Gaussian
mixture modeling of inverse regression.")
    (license license:gpl2+)))

(define-public r-pbivnorm
  (package
    (name "r-pbivnorm")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pbivnorm" version))
       (sha256
        (base32
         "05jzrjqxzbcf6z245hlk7sjxiszv9paadaaimvcx5y5qgi87vhq7"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://github.com/brentonk/pbivnorm")
    (synopsis "Vectorized bivariate normal CDF")
    (description
     "This package provides a vectorized R function for calculating
probabilities from a standard bivariate normal CDF.")
    (license license:gpl2+)))

(define-public r-lavaan
  (package
    (name "r-lavaan")
    (version "0.6-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lavaan" version))
       (sha256
        (base32
         "04kvsh2m6mnzlhv83phr3hjzy4sx1ck6f7dgsm7xb8cs84dnxszy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-mnormt" ,r-mnormt)
       ("r-numderiv" ,r-numderiv)
       ("r-pbivnorm" ,r-pbivnorm)))
    (home-page "http://lavaan.ugent.be")
    (synopsis "Latent variable analysis")
    (description
     "This package provides tools to fit a variety of latent variable models,
including confirmatory factor analysis, structural equation modeling and
latent growth curve models.")
    (license license:gpl2+)))

(define-public r-nonnest2
  (package
    (name "r-nonnest2")
    (version "0.5-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "nonnest2" version))
       (sha256
        (base32
         "1mnv4pa583ir9s03h952hk40lwdywr3g88g76sk1zsa54rcmn82c"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-compquadform" ,r-compquadform)
       ("r-lavaan" ,r-lavaan)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-sandwich" ,r-sandwich)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://cran.r-project.org/web/packages/nonnest2/")
    (synopsis "Tests of non-nested models")
    (description
     "This package allows for testing of non-nested models.  It includes tests
of model distinguishability and of model fit that can be applied to both
nested and non-nested models.  The package also includes functionality to
obtain confidence intervals associated with AIC and BIC.")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

(define-public r-penalized
  (package
    (name "r-penalized")
    (version "0.9-51")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "penalized" version))
       (sha256
        (base32
         "1zcrwa93mc27qj3g4ayc2k895r6g8q0g6qb2azmvj7wqk750va7a"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/penalized/")
    (synopsis "Penalized estimation in GLMs and in the Cox model")
    (description
     "This package provides tools for fitting possibly high dimensional
penalized regression models.  The penalty structure can be any combination of
an L1 penalty (lasso and fused lasso), an L2 penalty (ridge) and a positivity
constraint on the regression coefficients.  The supported regression models
are linear, logistic and Poisson regression and the Cox Proportional Hazards
model.  Cross-validation routines allow optimization of the tuning
parameters.")
    (license license:gpl2+)))

(define-public r-zim
  (package
    (name "r-zim")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ZIM" version))
       (sha256
        (base32
         "0scyfjn4ilsvha3x41c3b8bcfi31hlhwm77wn2a8hj5dsvnnmzig"))))
    (properties `((upstream-name . "ZIM")))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "https://github.com/biostatstudio/ZIM")
    (synopsis "Zero-inflated models (ZIM) for count time series with excess zeros")
    (description
     "Analyze count time series with excess zeros.  Two types of statistical
models are supported: Markov regression and state-space models.  They are also
known as observation-driven and parameter-driven models respectively in the
time series literature.  The functions used for Markov regression or
observation-driven models can also be used to fit ordinary regression models
with independent data under the zero-inflated Poisson (ZIP) or zero-inflated
negative binomial (ZINB) assumption.  The package also contains miscellaneous
functions to compute density, distribution, quantile, and generate random
numbers from ZIP and ZINB distributions.")
    (license license:gpl3)))

(define-public r-nor1mix
  (package
    (name "r-nor1mix")
    (version "1.3-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "nor1mix" version))
       (sha256
        (base32
         "1817wcvlmxs70vs4db0jkxd7i037744zz8ay3c2a9949z29fxr4w"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/nor1mix/")
    (synopsis "Normal (1-d) mixture models")
    (description
     "This package provides S3 classes and methods for one-dimensional normal
mixture models, for, e.g., density estimation or clustering algorithms
research and teaching; it provides the widely used Marron-Wand densities.  It
also provides tools for efficient random number generation and graphics.")
    (license license:gpl2+)))

(define-public r-beanplot
  (package
    (name "r-beanplot")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "beanplot" version))
       (sha256
        (base32
         "0wmkr704fl8kdxkjwmaxw2a2h5dwzfgsgpncnk2p2wd4768jknj9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/beanplot/")
    (synopsis "Visualization via beanplots")
    (description
     "This package provides beanplots, an alternative to
boxplot/stripchart/violin plots.  It can be used to plot univariate comparison
graphs.")
    (license license:gpl2)))

(define-public r-pbdzmq
  (package
    (name "r-pbdzmq")
    (version "0.3-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pbdZMQ" version))
       (sha256
        (base32
         "1jkfcfhspvqra7vbllrvkz3jx8j7d0ang6zzcdjgpb7200sc29mf"))))
    (properties `((upstream-name . "pbdZMQ")))
    (build-system r-build-system)
    (inputs
     `(("zeromq" ,zeromq)
       ("zlib" ,zlib)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://pbdr.org/")
    (synopsis "R interface to ZeroMQ")
    (description
     "ZeroMQ is a well-known library for high-performance asynchronous
messaging in scalable, distributed applications.  This package provides high
level R wrapper functions to easily utilize ZeroMQ.  The main focus is on
interactive client/server programming frameworks.  A few wrapper functions
compatible with @code{rzmq} are also provided.")
    (license license:gpl3)))

(define-public r-repr
  (package
    (name "r-repr")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "repr" version))
       (sha256
        (base32
         "15jz780w4nd9qjd1g3gq8f5lkh60p2v3ig3hm5kl1rg3z4cf0gvl"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-pillar" ,r-pillar)))
    (home-page "https://cran.r-project.org/web/packages/repr/")
    (synopsis "Serializable representations")
    (description
     "This package provides string and binary representations of objects for
several formats and MIME types.")
    (license license:gpl3)))

(define-public r-irdisplay
  (package
    (name "r-irdisplay")
    (version "0.7.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "IRdisplay" version))
       (sha256
        (base32
         "12chk53nf4zckgc4yl7gbvd7m5dvli52inp5b3f0zvcjvfncksli"))))
    (properties `((upstream-name . "IRdisplay")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-repr" ,r-repr)))
    (home-page "https://cran.r-project.org/web/packages/IRdisplay/")
    (synopsis "Jupyter display machinery")
    (description
     "This package provides an interface to the rich display capabilities of
Jupyter front-ends (e.g. Jupyter Notebook).  It is designed to be used from a
running IRkernel session.")
    (license license:expat)))

(define-public r-irkernel
  (package
    (name "r-irkernel")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "IRkernel" version))
       (sha256
        (base32
         "1viqxs91dys1z4cf7gb59rmqvzb8lc7jdp4azrpmhgwa8qf46s94"))))
    (properties `((upstream-name . "IRkernel")))
    (build-system r-build-system)
    (arguments
     `(#:phases
       (modify-phases %standard-phases
         (add-after 'install 'install-kernelspec
           (lambda* (#:key outputs #:allow-other-keys)
             (let ((out (assoc-ref outputs "out")))
               (setenv "HOME" "/tmp")
               (invoke "jupyter" "kernelspec" "install"
                       "--name" "ir"
                       "--prefix" out
                       (string-append out "/site-library/IRkernel/kernelspec"))
               ;; Record the absolute file name of the 'R' executable in
               ;; 'kernel.json'.
               (substitute* (string-append out "/share/jupyter"
                                           "/kernels/ir/kernel.json")
                 (("\\[\"R\",")
                  (string-append "[\"" (which "R") "\",")))
               #t))))))
    (inputs
     `(("jupyter" ,jupyter)))
    (propagated-inputs
     `(("r-crayon" ,r-crayon)
       ("r-digest" ,r-digest)
       ("r-evaluate" ,r-evaluate)
       ("r-irdisplay" ,r-irdisplay)
       ("r-jsonlite" ,r-jsonlite)
       ;; sets R_LIBS_SITE, so R can actually find this package (IRkernel)
       ("r-minimal" ,r-minimal)
       ("r-pbdzmq" ,r-pbdzmq)
       ("r-repr" ,r-repr)
       ("r-uuid" ,r-uuid)))
    (home-page "https://cran.r-project.org/web/packages/IRkernel/")
    (synopsis "Native R kernel for Jupyter")
    (description
     "The R kernel for the Jupyter environment executes R code which the
front-end (Jupyter Notebook or other front-ends) submits to the kernel via the
network.")
    (license license:expat)))

(define-public r-gmodels
  (package
    (name "r-gmodels")
    (version "2.18.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gmodels" version))
       (sha256
        (base32
         "0s8kd8krqk4kwv2zqxpsfy3w8qdwf5naf4b5l383vidq9sil0qb2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gdata" ,r-gdata)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/gmodels/")
    (synopsis "Various R programming tools for model fitting")
    (description
     "This package provides various R programming tools for model fitting.")
    (license license:gpl2)))

(define-public r-apcluster
  (package
    (name "r-apcluster")
    (version "1.4.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "apcluster" version))
       (sha256
        (base32
         "0lzf2jqm56i74wif6x5sw3j0w2qc4sni49zq2fgbl89b7lwkvchj"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/apcluster/")
    (synopsis "Affinity propagation clustering")
    (description
     "This package implements affinity propagation clustering introduced by
Frey and Dueck (2007).  The package further provides leveraged affinity
propagation and an algorithm for exemplar-based agglomerative clustering that
can also be used to join clusters obtained from affinity propagation.  Various
plotting functions are available for analyzing clustering results.")
    (license license:gpl2+)))

(define-public r-valr
  (package
    (name "r-valr")
    (version "0.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "valr" version))
       (sha256
        (base32
         "14jhrwkiwmha3vlmm7b50n2xxyizj6ddmy89gb20mpzq7qhz1ika"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-broom" ,r-broom)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-rcpp" ,r-rcpp)
       ("r-readr" ,r-readr)
       ("r-rlang" ,r-rlang)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)))
    (home-page "http://github.com/rnabioco/valr")
    (synopsis "Genome interval arithmetic in R")
    (description
     "This package enables you to read and manipulate genome intervals and
signals.  It provides functionality similar to command-line tool suites within
R, enabling interactive analysis and visualization of genome-scale data.")
    (license license:expat)))

(define-public r-rematch2
  (package
    (name "r-rematch2")
    (version "2.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rematch2" version))
       (sha256
        (base32
         "00cznm6rk33b53w7zybkz7549bnydc66znpi5mb0xd24pmqp0rvq"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-tibble" ,r-tibble)))
    (home-page "https://github.com/r-lib/rematch2")
    (synopsis "Tidy output from regular expression matching")
    (description
     "This package provides wrappers on @code{regexpr} and @code{gregexpr} to
return the match results in tidy data frames.")
    (license license:expat)))

(define-public r-picante
  (package
    (name "r-picante")
    (version "1.8.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "picante" version))
       (sha256
        (base32
         "1b16zm8zjjsl181b8krkdcrbcw347kf772c4w7y5332qmfi7jhz0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ape" ,r-ape)
       ("r-nlme" ,r-nlme)
       ("r-vegan" ,r-vegan)))
    (home-page "https://cran.r-project.org/web/packages/picante/")
    (synopsis "Integrating phylogenies and ecology")
    (description
     "This package provides functions for phylocom integration, community
analyses, null-models, traits and evolution.  It implements numerous
ecophylogenetic approaches including measures of community phylogenetic and
trait diversity, phylogenetic signal, estimation of trait values for
unobserved taxa, null models for community and phylogeny randomizations, and
utility functions for data input/output and phylogeny plotting.  A full
description of package functionality and methods are provided by Kembel et
al. (2010).")
    (license license:gpl2)))

(define-public r-reinforcelearn
  (package
    (name "r-reinforcelearn")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "reinforcelearn" version))
       (sha256
        (base32
         "176z2q69p24i29a8sh19xxn2zl3h1z2ixdssr5i6m4yvkvdrvv3b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-checkmate" ,r-checkmate)
       ("r-nnet" ,r-nnet)
       ("r-purrr" ,r-purrr)
       ("r-r6" ,r-r6)))
    (home-page "https://markusdumke.github.io/reinforcelearn")
    (synopsis "Reinforcement learning")
    (description
     "This package implements reinforcement learning environments and
algorithms as described in Sutton & Barto (1998).  The Q-Learning algorithm
can be used with function approximation, eligibility traces (Singh & Sutton,
1996) and experience replay (Mnih et al., 2013).")
    (license license:expat)))

(define-public r-lemon
  (package
    (name "r-lemon")
    (version "0.4.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lemon" version))
       (sha256
        (base32
         "0wsn5bfg10wq4dnrgpyraz2bzx9p19c7hf1pwj3h4zmpqfgsdbpw"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-gtable" ,r-gtable)
       ("r-knitr" ,r-knitr)
       ("r-lattice" ,r-lattice)
       ("r-plyr" ,r-plyr)
       ("r-scales" ,r-scales)))
    (home-page "https://github.com/stefanedwards/lemon")
    (synopsis "Freshen up your ggplot2 plots")
    (description
     "This package provides functions for working with legends and axis lines
of ggplot2, facets that repeat axis lines on all panels, and some knitr
extensions.")
    (license license:gpl3)))

(define-public r-wgaim
  (package
    (name "r-wgaim")
    (version "2.0-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "wgaim" version))
       (sha256
        (base32 "1qiyfkpsbzjr9xsq5kqq6rlqpndngkn2irdfh3gyi45h6hn118j4"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-qtl" ,r-qtl)))
    (home-page "https://cran.r-project.org/web/packages/wgaim")
    (synopsis "Whole genome average interval mapping for QTL detection")
    (description
     "This package integrates sophisticated mixed modelling methods with a
whole genome approach to detecting significant QTL in linkage maps.")
    (license license:gpl2+)))

(define-public r-bedr
  (package
    (name "r-bedr")
    (version "1.0.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bedr" version))
       (sha256
        (base32
         "0zpqvyjgwyqawxm8qrhcv8zq2b3yxgcqkkc87br29yrl7sjb8h6j"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-r-utils" ,r-r-utils)
       ("r-testthat" ,r-testthat)
       ("r-venndiagram" ,r-venndiagram)
       ("r-yaml" ,r-yaml)
       ("bedops" ,bedops)
       ("bedtools" ,bedtools)
       ("htslib" ,htslib))) ; for tabix
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://cran.r-project.org/web/packages/bedr")
    (synopsis "Genomic region processing")
    (description
     "This package is for genomic regions processing using command line tools
such as BEDTools, BEDOPS and Tabix.  These tools offer scalable and efficient
utilities to perform genome arithmetic e.g indexing, formatting and merging.
The bedr package's API enhances access to these tools as well as offers
additional utilities for genomic regions processing.")
    (license license:gpl2)))

(define-public r-sets
  (package
    (name "r-sets")
    (version "1.0-18")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sets" version))
       (sha256
        (base32
         "16v7650p47khqrbbw0z98llmwmmhswqmhri0n7nrfhdqwmby1lbl"))))
    (properties `((upstream-name . "sets")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/sets")
    (synopsis "Sets, generalized sets, customizable sets and intervals")
    (description
     "This package provides data structures and basic operations for ordinary
sets, generalizations such as fuzzy sets, multisets, and fuzzy multisets,
customizable sets, and intervals.")
    (license license:gpl2)))

(define-public r-partitions
  (package
    (name "r-partitions")
    (version "1.9-22")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "partitions" version))
       (sha256
        (base32
         "1qqy4df28wy4q0g572azrj171jlhvrnzbh7x0wr2g7v6gr20y0ns"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gmp" ,r-gmp)
       ("r-polynom" ,r-polynom)
       ("r-sets" ,r-sets)))
    (home-page "https://cran.r-project.org/web/packages/partitions")
    (synopsis "Additive partitions of integers")
    (description
     "This package provides tools to enumerates the partitions, unequal
partitions, and restricted partitions of an integer; the three corresponding
partition functions are also given.")
    ;; Any version of the GPL
    (license license:gpl2+)))

(define-public r-brobdingnag
  (package
    (name "r-brobdingnag")
    (version "1.2-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Brobdingnag" version))
       (sha256
        (base32
         "1m3ajvcksqfck5l5hj5xiflj4ry6d896ybv4f0xxks8chgnwmv0r"))))
    (properties `((upstream-name . "Brobdingnag")))
    (build-system r-build-system)
    (home-page "https://github.com/RobinHankin/Brobdingnag.git")
    (synopsis "Very large numbers in R")
    (description
     "This package handles very large numbers in R.  Real numbers are held
using their natural logarithms, plus a logical flag indicating sign.  The
package includes a vignette that gives a step-by-step introduction to using S4
methods.")
    ;; Any version of the GPL
    (license license:gpl2+)))

(define-public r-untb
  (package
    (name "r-untb")
    (version "1.7-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "untb" version))
       (sha256
        (base32
         "1i7m4vfslsix98dwx4jlrsldm7fhhfp25gr7aapcxqxms7ryaby6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-brobdingnag" ,r-brobdingnag)
       ("r-partitions" ,r-partitions)
       ("r-polynom" ,r-polynom)))
    (home-page "https://github.com/RobinHankin/untb.git")
    (synopsis "Ecological drift under the UNTB")
    (description
     "This package provides numerical simulations, and visualizations, of
Hubbell's @dfn{Unified Neutral Theory of Biodiversity} (UNTB).")
    (license license:gpl2+)))

(define-public r-stepwise
  (package
    (name "r-stepwise")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "stepwise" version))
       (sha256
        (base32
         "1lbx1bxwkf9dw6q46w40pp7h5nkxgghmx8rkpaymm6iybc7gyir2"))))
    (build-system r-build-system)
    (home-page "https://stat.sfu.ca/statgen/research/stepwise.html")
    (synopsis "Stepwise detection of recombination breakpoints")
    (description
     "This package provides a stepwise approach to identifying recombination
breakpoints in a genomic sequence alignment.")
    (license license:gpl2+)))

(define-public r-snpmaxsel
  (package
    (name "r-snpmaxsel")
    (version "1.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SNPmaxsel" version))
       (sha256
        (base32
         "0pjvixwqzjd3jwccc8yqq9c76afvbmfq0z1w0cwyj8bblrjpx13z"))))
    (properties `((upstream-name . "SNPmaxsel")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-combinat" ,r-combinat)
       ("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://cran.r-project.org/web/packages/SNPmaxsel/index.html")
    (synopsis "Maximally selected statistics for SNP data")
    (description
     "This package implements asymptotic methods related to maximally selected
statistics, with applications to @dfn{single-nucleotide polymorphism} (SNP)
data.")
    (license license:gpl2+)))

(define-public r-acsnminer
  (package
    (name "r-acsnminer")
    (version "0.16.8.25")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "ACSNMineR" version))
              (sha256
               (base32
                "0gh604s8qall6zfjlwcg2ilxjvz08dplf9k5g47idhv43scm748l"))))
    (properties `((upstream-name . "ACSNMineR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)))
    (home-page "https://cran.r-project.org/web/packages/ACSNMineR")
    (synopsis "Gene enrichment analysis")
    (description
     "This package provides tools to compute and represent gene set enrichment
or depletion from your data based on pre-saved maps from the @dfn{Atlas of
Cancer Signalling Networks} (ACSN) or user imported maps.  The gene set
enrichment can be run with hypergeometric test or Fisher exact test, and can
use multiple corrections.  Visualization of data can be done either by
barplots or heatmaps.")
    (license license:gpl2+)))

(define-public r-seqinr
  (package
    (name "r-seqinr")
    (version "3.6-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "seqinr" version))
       (sha256
        (base32
         "0j30za6kji6y3v09cvcydiacnp65pv6ig8aw7cydl47l5s9chky4"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ade4" ,r-ade4)
       ("r-segmented" ,r-segmented)))
    (inputs
     `(("zlib" ,zlib)))
    (home-page "http://seqinr.r-forge.r-project.org/")
    (synopsis "Biological sequences retrieval and analysis")
    (description
     "This package provides tools for exploratory data analysis and data
visualization of biological sequence (DNA and protein) data.  It also includes
utilities for sequence data management under the ACNUC system.")
    (license license:gpl2+)))

(define-public r-units
  (package
    (name "r-units")
    (version "0.6-6")
    (source
      (origin
        (method url-fetch)
        (uri (cran-uri "units" version))
        (sha256
          (base32
            "11x6xz1fbml28xmrhgn4sii9vfyj3gyfc1dfxahdg9cszdmcgdnh"))))
    (build-system r-build-system)
    (inputs
     `(("udunits" ,udunits)))
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/r-quantities/units/")
    (synopsis "Measurement Units for R Vectors")
    (description
      "This package provides support for measurement units in R vectors,
matrices and arrays: automatic propagation, conversion, derivation and
simplification of units; raising errors in case of unit incompatibility.  It
is compatible with the @code{POSIXct}, @code{Date} and @code{difftime}
classes.")
    (license license:gpl2)))

(define-public r-classint
  (package
    (name "r-classint")
    (version "0.4-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "classInt" version))
       (sha256
        (base32
         "0w980hrw8sgfdfyd5dsimalq7gwhvqm7507abk7k363pvgks23dv"))))
    (properties `((upstream-name . "classInt")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-class" ,r-class)
       ("r-e1071" ,r-e1071)
       ("r-kernsmooth" ,r-kernsmooth)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://github.com/r-spatial/classInt/")
    (synopsis "Choose univariate class intervals")
    (description
     "This package provides selected commonly used methods for choosing
univariate class intervals for mapping or other graphics purposes.")
    (license license:gpl2+)))

(define-public r-spdata
  (package
    (name "r-spdata")
    (version "0.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "spData" version))
       (sha256
        (base32
         "1v66qkvsx77hvv5c78v760yp0hknf7xzcjir2ri3ha456mz79yl5"))))
    (properties `((upstream-name . "spData")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-raster" ,r-raster)
       ("r-sp" ,r-sp)))
    (home-page "https://github.com/Nowosad/spData")
    (synopsis "Datasets for spatial analysis")
    (description
     "This a package containing diverse spatial datasets for demonstrating,
benchmarking and teaching spatial data analysis.  It includes R data of class
@code{sf}, @code{Spatial}, and @code{nb}.  It also contains data stored in a
range of file formats including GeoJSON, ESRI Shapefile and GeoPackage.  Some
of the datasets are designed to illustrate specific analysis techniques.
@code{cycle_hire()} and @code{cycle_hire_osm()}, for example, are designed to
illustrate point pattern analysis techniques.")
    (license license:cc0)))

(define-public r-learnbayes
  (package
    (name "r-learnbayes")
    (version "2.15.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "LearnBayes" version))
       (sha256
        (base32
         "0ch54v2zz2yyyk0lvn5rfikdmyz1qh9j1wk3585wl8v58mc0h4cv"))))
    (properties `((upstream-name . "LearnBayes")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/LearnBayes")
    (synopsis "Functions for learning Bayesian inference")
    (description
     "This package provides a collection of functions helpful in learning the
basic tenets of Bayesian statistical inference.  It contains functions for
summarizing basic one and two parameter posterior distributions and predictive
distributions.  It contains MCMC algorithms for summarizing posterior
distributions defined by the user.  It also contains functions for regression
models, hierarchical models, Bayesian tests, and illustrations of Gibbs
sampling.")
    (license license:gpl2+)))

(define-public r-deldir
  (package
    (name "r-deldir")
    (version "0.1-25")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "deldir" version))
       (sha256
        (base32
         "0kdglv8rc1pb4ilcid4xc9wpv5kkj2y6x6wg7919k3hya7mz58ph"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/deldir")
    (synopsis "Delaunay triangulation and Dirichlet (Voronoi) tessellation")
    (description
     "This package provides tools for calculating the Delaunay triangulation
and the Dirichlet or Voronoi tessellation (with respect to the entire plane)
of a planar point set.  It plots triangulations and tessellations in various
ways, clips tessellations to sub-windows, calculates perimeters of
tessellations, and summarizes information about the tiles of the
tessellation.")
    (license license:gpl2+)))

(define-public r-sf
  (package
    (name "r-sf")
    (version "0.9-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sf" version))
       (sha256
        (base32
         "117r9l3v7nkdj9bfy6qr0yz0gd5bv0pwnkc9vk2gv3xqj0h1fpf6"))))
    (build-system r-build-system)
    (inputs
     `(("gdal" ,gdal)
       ("geos" ,geos)
       ("proj" ,proj.4)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-classint" ,r-classint)
       ("r-dbi" ,r-dbi)
       ("r-magrittr" ,r-magrittr)
       ("r-rcpp" ,r-rcpp)
       ("r-units" ,r-units)))
    (native-inputs
     `(("pkg-config" ,pkg-config)
       ("r-knitr" ,r-knitr)))
    (home-page "https://github.com/r-spatial/sf/")
    (synopsis "Simple features for R")
    (description
     "This package provides support for simple features, a standardized way to
encode spatial vector data.  It binds to GDAL for reading and writing data, to
GEOS for geometrical operations, and to PROJ for projection conversions and
datum transformations.")
    ;; Either of these licenses
    (license (list license:gpl2 license:expat))))

(define-public r-spdep
  (package
    (name "r-spdep")
    (version "1.1-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "spdep" version))
       (sha256
        (base32
         "1f8cjffqqc6rnb3n4qym70ca6nz2kvrsd3g587wrqdr79nnbwnrk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-coda" ,r-coda)
       ("r-deldir" ,r-deldir)
       ("r-expm" ,r-expm)
       ("r-gmodels" ,r-gmodels)
       ("r-learnbayes" ,r-learnbayes)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-nlme" ,r-nlme)
       ("r-sf" ,r-sf)
       ("r-sp" ,r-sp)
       ("r-spdata" ,r-spdata)))
    (home-page "https://github.com/r-spatial/spdep/")
    (synopsis "Spatial dependence: weighting schemes, statistics and models")
    (description
     "This package provides a collection of functions to create spatial
weights matrix objects from polygon contiguities, from point patterns by
distance and tessellations, for summarizing these objects, and for permitting
their use in spatial data analysis, including regional aggregation by minimum
spanning tree.")
    (license license:gpl2+)))

(define-public r-adegenet
  (package
    (name "r-adegenet")
    (version "2.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adegenet" version))
       (sha256
        (base32
         "01fgrgbiddz2q4l3mx637hhwbs7r0c43yw7vpwl8p8pwbm3nykz0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ade4" ,r-ade4)
       ("r-ape" ,r-ape)
       ("r-boot" ,r-boot)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-igraph" ,r-igraph)
       ("r-mass" ,r-mass)
       ("r-reshape2" ,r-reshape2)
       ("r-seqinr" ,r-seqinr)
       ("r-shiny" ,r-shiny)
       ("r-spdep" ,r-spdep)
       ("r-vegan" ,r-vegan)))
    (home-page "https://github.com/thibautjombart/adegenet")
    (synopsis "Exploratory analysis of genetic and genomic data")
    (description
     "This package provides a toolset for the exploration of genetic and
genomic data.  Adegenet provides formal (S4) classes for storing and handling
various genetic data, including genetic markers with varying ploidy and
hierarchical population structure (@code{genind} class), alleles counts by
populations (@code{genpop}), and genome-wide SNP data (@code{genlight}).  It
also implements original multivariate methods (DAPC, sPCA), graphics,
statistical tests, simulation tools, distance and similarity measures, and
several spatial methods.  A range of both empirical and simulated datasets is
also provided to illustrate various methods.")
    (license license:gpl2+)))

(define-public r-pegas
  (package
    (name "r-pegas")
    (version "0.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pegas" version))
       (sha256
        (base32 "002i7s4g0nhnq0v05gs0yssqiyhpq2f7rw2rhn31hsbgxc86frvy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-adegenet" ,r-adegenet)
       ("r-ape" ,r-ape)))
    (home-page "http://ape-package.ird.fr/pegas.html")
    (synopsis "Population and evolutionary genetics analysis system")
    (description
     "This package provides functions for reading, writing, plotting,
analysing, and manipulating allelic and haplotypic data, including from VCF
files, and for the analysis of population nucleotide sequences and
micro-satellites including coalescent analyses, linkage disequilibrium,
population structure (Fst, Amova) and equilibrium (HWE), haplotype networks,
minimum spanning tree and network, and median-joining networks.")
    (license license:gpl2+)))

(define-public r-rmetasim
  (package
    (name "r-rmetasim")
    (version "3.1.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rmetasim" version))
       (sha256
        (base32
         "0rdkhfgyr97r2d1kd9g8ipb2pn563qxm1y4m9z678q0kqan2ddl0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ade4" ,r-ade4)
       ("r-adegenet" ,r-adegenet)
       ("r-gtools" ,r-gtools)
       ("r-pegas" ,r-pegas)))
    (home-page "https://cran.r-project.org/web/packages/rmetasim")
    (synopsis "Individual-based population genetic simulation environment")
    (description
     "This package provides an interface between R and the metasim simulation
engine.  The simulation environment is documented in: Strand, A.(2002),
Metasim 1.0: an individual-based environment for simulating population
genetics of complex population dynamics.")
    ;; Any GPL version
    (license license:gpl2+)))

(define-public r-genetics
  (package
    (name "r-genetics")
    (version "1.3.8.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "genetics" version))
       (sha256
        (base32
         "1v0ylnia6c44v356dsmnkx6054vcxazpzsrdh3yph5ch5vg6gjrh"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-combinat" ,r-combinat)
       ("r-gdata" ,r-gdata)
       ("r-gtools" ,r-gtools)
       ("r-mass" ,r-mass)
       ("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://cran.r-project.org/web/packages/genetics/")
    (synopsis "Population genetics")
    (description
     "This package provides classes and methods for handling genetic data.
It includes classes to represent genotypes and haplotypes at single markers up
to multiple markers on multiple chromosomes.  Function include allele
frequencies, flagging homo/heterozygotes, flagging carriers of certain
alleles, estimating and testing for Hardy-Weinberg disequilibrium, estimating
and testing for linkage disequilibrium, ...")
    ;; Any GPL version.
    (license license:gpl2+)))

(define-public r-snp-plotter
  (package
    (name "r-snp-plotter")
    (version "0.5.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "snp.plotter" version))
       (sha256
        (base32
         "16apsqvkah5l0d5qcwp3lq2jspkb6n62wzr0wskmj84jblx483vv"))))
    (properties `((upstream-name . "snp.plotter")))
    (build-system r-build-system)
    (propagated-inputs `(("r-genetics" ,r-genetics)))
    (home-page "https://cran.r-project.org/web/packages/snp.plotter/")
    (synopsis "Plot p-values using single SNP and/or haplotype data")
    (description
     "This package helps you create plots of p-values using single SNP and/or
haplotype data.  Main features of the package include options to display a
@dfn{linkage disequilibrium} (LD) plot and the ability to plot multiple
datasets simultaneously.  Plots can be created using global and/or individual
haplotype p-values along with single SNP p-values.  Images are created as
either PDF/EPS files.")
    (license license:gpl2+)))

(define-public r-polspline
  (package
    (name "r-polspline")
    (version "1.1.17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "polspline" version))
       (sha256
        (base32 "0c7fnxpqpy3hibiim4yib6l6bq363s97wwvllxp4lp8h06fjcyyn"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/polspline/")
    (synopsis "Polynomial spline routines")
    (description
     "This package provides routines for the polynomial spline fitting
routines hazard regression, hazard estimation with flexible tails, logspline,
lspec, polyclass, and polymars.")
    (license license:gpl2+)))

(define-public r-rms
  (package
    (name "r-rms")
    (version "5.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rms" version))
       (sha256
        (base32 "19knh1sw0icw6jh9wfb2hq5jf49i2qfvp9myvqm5paa495689x9q"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-hmisc" ,r-hmisc)
       ("r-htmltable" ,r-htmltable)
       ("r-htmltools" ,r-htmltools)
       ("r-lattice" ,r-lattice)
       ("r-multcomp" ,r-multcomp)
       ("r-nlme" ,r-nlme)
       ("r-polspline" ,r-polspline)
       ("r-quantreg" ,r-quantreg)
       ("r-rpart" ,r-rpart)
       ("r-sparsem" ,r-sparsem)
       ("r-survival" ,r-survival)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "http://biostat.mc.vanderbilt.edu/rms")
    (synopsis "Regression modeling strategies")
    (description
     "This is a package for regression modeling, testing, estimation,
validation, graphics, prediction, and typesetting by storing enhanced model
design attributes in the fit.  The rms package is a collection of functions
that assist with and streamline modeling.  It also contains functions for
binary and ordinal logistic regression models, ordinal models for continuous Y
with a variety of distribution families, and the Buckley-James multiple
regression model for right-censored responses, and implements penalized
maximum likelihood estimation for logistic and ordinary linear models.  The
package works with almost any regression model, but it was especially written
to work with binary or ordinal regression models, Cox regression, accelerated
failure time models, ordinary linear models, the Buckley-James model,
generalized least squares for serially or spatially correlated observations,
generalized linear models, and quantile regression.")
    (license license:gpl2+)))

(define-public r-haplo-stats
  (package
    (name "r-haplo-stats")
    (version "1.7.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "haplo.stats" version))
       (sha256
        (base32
         "19kxascqq5qz0zdxx0w837ji207y1z2ggxkl4vmlbay03k2dw2mx"))))
    (properties `((upstream-name . "haplo.stats")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rms" ,r-rms)))
    (native-inputs
     `(("r-r-rsp" ,r-r-rsp))) ; for vignettes
    (home-page "https://www.mayo.edu/research/labs/statistical-genetics-genetic-epidemiology/software")
    (synopsis "Analysis of haplotypes when linkage phase is ambiguous")
    (description
     "This package provides routines for the analysis of indirectly measured
haplotypes.  The statistical methods assume that all subjects are unrelated
and that haplotypes are ambiguous (due to unknown linkage phase of the genetic
markers).  The main functions are: @code{haplo.em()}, @code{haplo.glm()},
@code{haplo.score()}, and @code{haplo.power()}; all of which have detailed
examples in the vignette.")
    (license license:gpl2+)))

(define-public r-bqtl
  (package
    (name "r-bqtl")
    (version "1.0-32")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bqtl" version))
       (sha256
        (base32
         "0jjqgsm9fmvz5nkgz608xfljjpmaf4rs4f7kxvpqn4b1l9s5lhci"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "http://famprevmed.ucsd.edu/faculty/cberry/bqtl/")
    (synopsis "Bayesian QTL mapping toolkit")
    (description
     "This is a QTL mapping toolkit for inbred crosses and recombinant inbred
lines.  It includes maximum likelihood and Bayesian tools.")
    (license license:gpl2+)))

(define-public r-ibdreg
  (package
    (name "r-ibdreg")
    (version "0.2.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ibdreg" version))
       (sha256
        (base32
         "1kaa5q1byi30wzr0mw4w2cv1ssxprzcwf91wrpqwkgcsdy7dkh2g"))))
    (build-system r-build-system)
    (home-page "https://www.mayo.edu/research/labs/\
statistical-genetics-genetic-epidemiology/software")
    (synopsis "Regression methods for IBD linkage with covariates")
    (description
     "This package provides a method to test genetic linkage with covariates
by regression methods with response IBD sharing for relative pairs.  Account
for correlations of IBD statistics and covariates for relative pairs within
the same pedigree.")
    (license license:gpl2+)))

(define-public r-dlmap
  (package
    (name "r-dlmap")
    (version "1.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dlmap" version))
       (sha256
        (base32
         "0s6wlkggkm3qndwyvw72xv1n0mcjb7ss3ajbq2ll6rv30splq0db"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ibdreg" ,r-ibdreg)
       ("r-mgcv" ,r-mgcv)
       ("r-nlme" ,r-nlme)
       ("r-qtl" ,r-qtl)
       ("r-wgaim" ,r-wgaim)))
    (home-page "https://cran.r-project.org/web/packages/dlmap/")
    (synopsis "Detection localization mapping for QTL")
    (description
     "This is package for QTL mapping in a mixed model framework with separate
detection and localization stages.  The first stage detects the number of QTL
on each chromosome based on the genetic variation due to grouped markers on
the chromosome; the second stage uses this information to determine the most
likely QTL positions.  The mixed model can accommodate general fixed and
random effects, including spatial effects in field trials and pedigree
effects.  It is applicable to backcrosses, doubled haploids, recombinant
inbred lines, F2 intercrosses, and association mapping populations.")
    (license license:gpl2)))

(define-public r-ldheatmap
  (package
    (name "r-ldheatmap")
    (version "0.99-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "LDheatmap" version))
       (sha256
        (base32
         "1r0j8bihi5z1x0sgaf7dwzpsw9i0nc1vylvipvc0cia2ka1lr9dc"))))
    (properties `((upstream-name . "LDheatmap")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-genetics" ,r-genetics)
       ("r-rcpp" ,r-rcpp)
       ("r-snpstats" ,r-snpstats)))
    (home-page "https://stat.sfu.ca/statgen/research/ldheatmap.html")
    (synopsis "Graphical display of pairwise linkage disequilibria between SNPs")
    (description
     "This package provides tools to produce a graphical display, as a heat
map, of measures of pairwise linkage disequilibria between SNPs.  Users may
optionally include the physical locations or genetic map distances of each SNP
on the plot.")
    (license license:gpl3)))

(define-public r-hwde
  (package
    (name "r-hwde")
    (version "0.67")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hwde" version))
       (sha256
        (base32
         "0wb2f9i5qi7w77ygh8bvydfpr7j5x8dyvnnhdkajaz0wdcpkyaqy"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/hwde/")
    (synopsis "Models and tests for departure from Hardy-Weinberg equilibrium")
    (description
     "This package fits models for genotypic disequilibria, as described in
Huttley and Wilson (2000), Weir (1996) and Weir and Wilson (1986).  Contrast
terms are available that account for first order interactions between loci.
It also implements, for a single locus in a single population, a conditional
exact test for Hardy-Weinberg equilibrium.")
    (license license:gpl2+)))

(define-public r-tdthap
  (package
    (name "r-tdthap")
    (version "1.1-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tdthap" version))
       (sha256
        (base32
         "15qlj2bivvz3pizd8dq34wczbkbxhzqh3cqp1ixkdkprlyvcxj5k"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/tdthap/")
    (synopsis "TDT tests for extended haplotypes")
    (description
     "Functions and examples are provided for transmission/disequilibrium
tests for extended marker haplotypes, as in Clayton, D. and Jones, H. (1999)
\"Transmission/disequilibrium tests for extended marker haplotypes\".")
    (license license:artistic2.0)))

(define-public r-sparql
  (package
    (name "r-sparql")
    (version "1.16")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "SPARQL" version))
              (sha256
               (base32
                "0gak1q06yyhdmcxb2n3v0h9gr1vqd0viqji52wpw211qp6r6dcrc"))))
    (properties `((upstream-name . "SPARQL")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcurl" ,r-rcurl)
       ("r-xml" ,r-xml)))
    (home-page "https://cran.r-project.org/web/packages/SPARQL")
    (synopsis "SPARQL client for R")
    (description "This package provides an interface to use SPARQL to pose
SELECT or UPDATE queries to an end-point.")
    ;; The only license indication is found in the DESCRIPTION file,
    ;; which states GPL-3.  So we cannot assume GPLv3+.
    (license license:gpl3)))

(define-public r-bookdown
  (package
    (name "r-bookdown")
    (version "0.18")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "bookdown" version))
              (sha256
               (base32
                "1my6g16phx21v5cvfqcnjibh3zcv02xkix347aafd6a7r3hnxpq5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-knitr" ,r-knitr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-tinytex" ,r-tinytex)
       ("r-xfun" ,r-xfun)
       ("pandoc" ,ghc-pandoc)))
    (home-page "https://github.com/rstudio/bookdown")
    (synopsis "Authoring books and technical documents with R markdown")
    (description "This package provides output formats and utilities for
authoring books and technical documents with R Markdown.")
    (license license:gpl3)))

(define-public r-optparse
  (package
    (name "r-optparse")
    (version "1.6.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "optparse" version))
       (sha256
        (base32
         "0wyrc42ja3ab5szx46zmz8lm7vzfqxkjca0m0sms8g9hqbmmay6d"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-getopt" ,r-getopt)))
    (home-page "https://github.com/trevorld/optparse")
    (synopsis "Command line option parser")
    (description
     "This package provides a command line parser inspired by Python's
@code{optparse} library to be used with Rscript to write shebang scripts
that accept short and long options.")
    (license license:gpl2+)))

(define-public r-wgcna
  (package
    (name "r-wgcna")
    (version "1.69")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "WGCNA" version))
       (sha256
        (base32
         "022hkprnrafvggi8pkjffkvk1qlnibmbbxxrni00wkrdbga5589f"))))
    (properties `((upstream-name . "WGCNA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-annotationdbi" ,r-annotationdbi)
       ("r-doparallel" ,r-doparallel)
       ("r-dynamictreecut" ,r-dynamictreecut)
       ("r-fastcluster" ,r-fastcluster)
       ("r-foreach" ,r-foreach)
       ("r-go-db" ,r-go-db)
       ("r-hmisc" ,r-hmisc)
       ("r-impute" ,r-impute)
       ("r-rcpp" ,r-rcpp)
       ("r-survival" ,r-survival)
       ("r-matrixstats" ,r-matrixstats)
       ("r-preprocesscore" ,r-preprocesscore)))
    (home-page
     "http://www.genetics.ucla.edu/labs/horvath/CoexpressionNetwork/Rpackages/WGCNA/")
    (synopsis "Weighted correlation network analysis")
    (description
     "This package provides functions necessary to perform Weighted
Correlation Network Analysis on high-dimensional data.  It includes functions
for rudimentary data cleaning, construction and summarization of correlation
networks, module identification and functions for relating both variables and
modules to sample traits.  It also includes a number of utility functions for
data manipulation and visualization.")
    (license license:gpl2+)))

(define-public r-kernlab
  (package
    (name "r-kernlab")
    (version "0.9-29")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kernlab" version))
       (sha256
        (base32 "0vqhndl4zm7pvkfvq0f6i9cbrm7pij6kmdp7d7w39pa100x6knn3"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/kernlab")
    (synopsis "Kernel-based machine learning tools")
    (description
     "This package provides kernel-based machine learning methods for
classification, regression, clustering, novelty detection, quantile regression
and dimensionality reduction.  Among other methods @code{kernlab} includes
Support Vector Machines, Spectral Clustering, Kernel PCA, Gaussian Processes
and a QP solver.")
    (license license:gpl2)))

(define-public r-hierfstat
  (package
    (name "r-hierfstat")
    (version "0.04-22")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hierfstat" version))
       (sha256
        (base32
         "1fav2v2996v5kb1ffa6v5wxfm921syxg6as034vd3j4jfhdibyfx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ade4" ,r-ade4)
       ("r-adegenet" ,r-adegenet)
       ("r-gtools" ,r-gtools)))
    (home-page "https://cran.r-project.org/web/packages/hierfstat/")
    (synopsis "Estimation and tests of hierarchical F-statistics")
    (description
     "This package allows the estimation of hierarchical F-statistics from
haploid or diploid genetic data with any numbers of levels in the hierarchy,
following the algorithm of Yang (Evolution, 1998, 52(4):950-956).  Functions
are also given to test via randomisations the significance of each F and
variance components, using the likelihood-ratio statistics G.")
    (license license:gpl2+)))

(define-public r-hapassoc
  (package
    (name "r-hapassoc")
    (version "1.2-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hapassoc" version))
       (sha256
        (base32
         "0qs5jl0snzfchgpp6pabncwywxcmi743g91jvjiyyzw0lw85yv4s"))))
    (build-system r-build-system)
    (home-page "https://stat.sfu.ca/statgen/research/hapassoc.html")
    (synopsis "Inference of trait associations with SNP haplotypes")
    (description
     "Hapassoc performs likelihood inference of trait associations with
haplotypes and other covariates in @dfn{generalized linear models} (GLMs). The
functions are developed primarily for data collected in cohort or
cross-sectional studies.  They can accommodate uncertain haplotype phase and
handle missing genotypes at some SNPs.")
    (license license:gpl2)))

(define-public r-sampling
  (package
    (name "r-sampling")
    (version "2.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sampling" version))
       (sha256
        (base32
         "06pj7dan0mknpsblmlnk7am78qrnwgnql5vvx7vmbfvib7rj6s9m"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lpsolve" ,r-lpsolve)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/sampling/")
    (synopsis "Survey sampling")
    (description
     "This package provides functions for drawing and calibrating samples.")
    (license license:gpl2+)))

(define-public r-r2html
  (package
    (name "r-r2html")
    (version "2.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "R2HTML" version))
       (sha256
        (base32
         "00kxny7hajs9r2kw63qk7d03ggdxx2j1g8vbrmzp806y8aczvik9"))))
    (properties `((upstream-name . "R2HTML")))
    (build-system r-build-system)
    (home-page "https://github.com/nalimilan/R2HTML")
    (synopsis "HTML export for R objects")
    (description
     "This package includes HTML functions and methods to write in an HTML
file.  Thus, making HTML reports is easy.  It includes a function that allows
redirection on the fly, which appears to be very useful for teaching purposes,
as the student can keep a copy of the produced output to keep all that they
did during the course.  The package comes with a vignette describing how to
write HTML reports for statistical analysis.  Finally, a driver for Sweave
allows to parse HTML flat files containing R code and to automatically write
the corresponding outputs (tables and graphs).")
    (license license:gpl2+)))

(define-public r-rjava
  (package
    (name "r-rjava")
    (version "0.9-12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rJava" version))
       (sha256
        (base32
         "03vv0pj6san03c51iyqsyb1rwh3097dfpl2s8iswzzmc7k3shj12"))))
    (properties `((upstream-name . "rJava")))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (ice-9 match))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'set-JAVA_HOME
           (lambda* (#:key inputs #:allow-other-keys)
             (let ((jdk (assoc-ref inputs "jdk")))
               (setenv "JAVA_HOME" jdk)
               (setenv "JAVA" (which "java"))
               (setenv "JAR" (which "jar"))
               (setenv "JAVAC" (which "javac"))
               (setenv "JAVAH" (which "javah"))
               (setenv "JAVA_CPPFLAGS"
                       (string-append "-I" jdk "/include "
                                      "-I" jdk "/include/linux"))
               (match (find-files (string-append jdk "/jre/lib/") "libjvm.so")
                 ((lib) (setenv "JAVA_LIBS" lib))
                 (_ (error "Could not find libjvm.so"))))
             #t)))))
    (inputs
     `(("icu4c" ,icu4c)
       ("jdk" ,icedtea-8 "jdk")
       ("pcre" ,pcre)
       ("zlib" ,zlib)))
    (home-page "https://www.rforge.net/rJava/")
    (synopsis "Low-Level R to Java interface")
    (description
     "This package provides a low-level interface to the Java VM very much
like .C/.Call and friends.  It allows the creation of objects, calling methods
and accessing fields.")
    (license license:gpl2)))

(define-public r-svmisc
  (package
    (name "r-svmisc")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "svMisc" version))
       (sha256
        (base32
         "01r2a73wx2sh1njky961fxabx5wgddqqjqba6vjg0f3h8r3abmn2"))))
    (properties `((upstream-name . "svMisc")))
    (build-system r-build-system)
    (home-page "https://github.com/SciViews/svMisc")
    (synopsis "Miscellaneous functions for SciViews")
    (description
     "This package provides miscellaneous functions for SciViews or general
use, including tools to manage a temporary environment attached to the search
path for temporary variables you do not want to @code{save()} or
@code{load()}; test the current platform; showing progress bars, etc.")
    (license license:gpl2)))

(define-public r-xyz
  (package
    (name "r-xyz")
    (version "0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xyz" version))
       (sha256
        (base32
         "13w4sb4pvgciwr8wsz785dafj2k2kpx7znz46r5d32wx88vkycp4"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/xyz/")
    (synopsis "Algorithm for fast interaction search in high-dimensional data")
    (description
     "High dimensional interaction search by brute force requires a quadratic
computational cost in the number of variables.  The xyz algorithm provably
finds strong interactions in almost linear time.  For details of the algorithm
see: G. Thanei, N. Meinshausen and R. Shah (2016).  The xyz algorithm for fast
interaction search in high-dimensional data.")
    ;; Any version of the GPL.
    (license license:gpl2+)))

(define-public r-rttf2pt1
  (package
    (name "r-rttf2pt1")
    (version "1.3.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rttf2pt1" version))
       (sha256
        (base32
         "0b3f2zkmbyshn19cnaaf042d0zwf43l9jnkqizfhxxwb93a4c1jn"))))
    (properties `((upstream-name . "Rttf2pt1")))
    (build-system r-build-system)
    (home-page "https://github.com/wch/Rttf2pt1")
    (synopsis "Font conversion utility")
    (description
     "This package contains the program @code{ttf2pt1}, for use with the
@code{extrafont} package.")
    ;; Most of the files are covered under the Expat license.  Some files are
    ;; covered under BSD-3.  Deviations for individual files are recorded in
    ;; the LICENSE file.
    (license (list license:bsd-3 license:expat
                   (license:non-copyleft "file://LICENSE")))))

(define-public r-extrafontdb
  (package
    (name "r-extrafontdb")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "extrafontdb" version))
       (sha256
        (base32
         "115n42hfvv5h4nn4cfkfmkmn968py4lpy8zd0d6w5yylwpzbm8gs"))))
    (build-system r-build-system)
    (home-page "https://github.com/wch/extrafontdb")
    (synopsis "Database for the extrafont package")
    (description
     "This package holds the database for the @code{extrafont} package.")
    (license license:gpl2)))

(define-public r-extrafont
  (package
    (name "r-extrafont")
    (version "0.17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "extrafont" version))
       (sha256
        (base32
         "0b9k2n9sk23bh45hjgnkxpjyvpdrz1hx7kmxvmb4nhlhm1wpsv9g"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-extrafontdb" ,r-extrafontdb)
       ("r-rttf2pt1" ,r-rttf2pt1)))
    (home-page "https://github.com/wch/extrafont")
    (synopsis "Tools for using fonts in R")
    (description
     "The extrafont package makes it easier to use fonts other than the basic
PostScript fonts that R uses.  Fonts that are imported into extrafont can be
used with PDF or PostScript output files.  There are two hurdles for using
fonts in PDF (or Postscript) output files:

@enumerate
@item Making R aware of the font and the dimensions of the characters.
@item Embedding the fonts in the PDF file so that the PDF can be displayed
  properly on a device that doesn't have the font.  This is usually needed if
  you want to print the PDF file or share it with others.
@end enumerate

The extrafont package makes both of these things easier.")
    (license license:gpl2)))

(define-public r-xkcd
  (package
    (name "r-xkcd")
    (version "0.0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xkcd" version))
       (sha256
        (base32
         "1z2y0ihn68ppay7xkglhw7djki5654g6z4bbpyy41if57z9q554f"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-extrafont" ,r-extrafont)
       ("r-ggplot2" ,r-ggplot2)
       ("r-hmisc" ,r-hmisc)))
    (home-page "https://cran.r-project.org/web/packages/xkcd/")
    (synopsis "Plot ggplot2 graphics in the XKCD style")
    (description
     "This package provides the means to plot ggplot2 graphs in the style of
the XKCD web comic.")
    (license license:gpl3)))

(define-public r-msigdbr
  (package
    (name "r-msigdbr")
    (version "7.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "msigdbr" version))
       (sha256
        (base32
         "19p8z617m3my8la7n1qgb1s2msf940r372im3q30qkbcx3qxg3sd"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-magrittr" ,r-magrittr)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/igordot/msigdbr")
    (synopsis "MSigDB gene sets for multiple organisms")
    (description
     "This package provides the @dfn{Molecular Signatures Database} (MSigDB)
gene sets typically used with the @dfn{Gene Set Enrichment Analysis} (GSEA)
software in a standard R data frame with key-value pairs.  Included are the
original human gene symbols and Entrez IDs as well as the equivalents for
various frequently studied model organisms such as mouse, rat, pig, fly, and
yeast.")
    ;; The package is covered under the Expat license, but the upstream MSigDB
    ;; files are made available under the Creative Commons Attribution 4.0
    ;; International license.
    (license (list license:expat license:cc-by4.0))))

(define-public r-gridgraphics
  (package
    (name "r-gridgraphics")
    (version "0.5-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gridGraphics" version))
       (sha256
        (base32
         "0rlyc3xk8kfrfzbfd8n4javq3yxqd7lsfmi4q5n6s61srnrl6c1r"))))
    (properties `((upstream-name . "gridGraphics")))
    (build-system r-build-system)
    (home-page "https://github.com/pmur002/gridgraphics")
    (synopsis "Redraw base graphics using @code{grid} graphics")
    (description
     "This package provides functions to convert a page of plots drawn with
the @code{graphics} package into identical output drawn with the @code{grid}
package.  The result looks like the original @code{graphics}-based plot, but
consists of @code{grid} grobs and viewports that can then be manipulated with
@code{grid} functions (e.g., edit grobs and revisit viewports).")
    (license license:gpl2+)))

(define-public r-farver
  (package
    (name "r-farver")
    (version "2.0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "farver" version))
       (sha256
        (base32
         "1k75v07dsfkjra2gsgxg9s55cw3b46b1nh960kqphq7cg7gr058f"))))
    (build-system r-build-system)
    (home-page "https://github.com/thomasp85/farver")
    (synopsis "Vectorized color conversion and comparison")
    (description
     "The encoding of color can be handled in many different ways, using
different color spaces.  As different color spaces have different uses,
efficient conversion between these representations are important.  This
package provides a set of functions that gives access to very fast color space
conversion and comparisons implemented in C++, and offers 100-fold speed
improvements over the @code{convertColor} function in the @code{grDevices}
package.")
    (license license:expat)))

(define-public r-ggplotify
  (package
    (name "r-ggplotify")
    (version "0.0.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggplotify" version))
       (sha256
        (base32
         "0pfnp4lrissf21z7867kdm6slr979kchyva8iaf83i1302kscph3"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gridgraphics" ,r-gridgraphics)
       ("r-rvcheck" ,r-rvcheck)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/GuangchuangYu/ggplotify")
    (synopsis "Convert plots to @code{grob} or @code{ggplot} object")
    (description
     "This package provides tools to convert plot function calls (using
expression or formula) to @code{grob} or @code{ggplot} objects that are
compatible with the @code{grid} and @code{ggplot2} environment.  With this
package, we are able to e.g. use @code{cowplot} to align plots produced by
@code{base} graphics, @code{grid}, @code{lattice}, @code{vcd} etc. by
converting them to @code{ggplot} objects.")
    (license license:artistic2.0)))

(define-public r-triebeard
  (package
    (name "r-triebeard")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "triebeard" version))
       (sha256
        (base32
         "1hqyz57gph02c9fdc07lxz113bbklif3g18sw8jan6pakhhdc7dz"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/Ironholds/triebeard/")
    (synopsis "Radix trees in Rcpp")
    (description
     "Radix trees, or tries, are key-value data structures optimized for
efficient lookups, similar in purpose to hash tables.  This package provides
an implementation of radix trees for use in R programming and in developing
packages with Rcpp.")
    (license license:expat)))

(define-public r-tweenr
  (package
    (name "r-tweenr")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tweenr" version))
       (sha256
        (base32
         "0sq90pbln6lkc2q3zflhkxxwpqdw5dd7igrxhdnlynkdrmi83mpg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-farver" ,r-farver)
       ("r-magrittr" ,r-magrittr)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)))
    (home-page "https://github.com/thomasp85/tweenr")
    (synopsis "Interpolate data for smooth animations")
    (description
     "In order to create smooth animation between states of data, tweening is
necessary.  This package provides a range of functions for creating tweened
data that can be used as basis for animation.  Furthermore it adds a number of
vectorized interpolaters for common R data types such as numeric, date and
color.")
    (license license:expat)))

(define-public r-polyclip
  (package
    (name "r-polyclip")
    (version "1.10-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "polyclip" version))
       (sha256
        (base32
         "0jyk4maqiblvj095jd59dr76kbniyli3v3xvy0a72ljszq6vrnkl"))))
    (build-system r-build-system)
    (native-inputs `(("pkg-config" ,pkg-config)))
    (home-page "http://www.angusj.com/delphi/clipper.php")
    (synopsis "Polygon clipping")
    (description
     "This package provides an R port of the library Clipper.  It performs
polygon clipping operations (intersection, union, set minus, set difference)
for polygonal regions of arbitrary complexity, including holes.  It computes
offset polygons (spatial buffer zones, morphological dilations, Minkowski
dilations) for polygonal regions and polygonal lines.  It computes the
Minkowski Sum of general polygons.  There is a function for removing
self-intersections from polygon data.")
    (license license:boost1.0)))

(define-public r-urltools
  (package
    (name "r-urltools")
    (version "1.7.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "urltools" version))
       (sha256
        (base32
         "04x3my655dd287cbsszbnf75q0swmjlxxrblcsay7a8n3df3a830"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-triebeard" ,r-triebeard)))
    (home-page "https://github.com/Ironholds/urltools/")
    (synopsis "Vectorized tools for URL handling and parsing")
    (description
     "This package provides a toolkit for all URL-handling needs, including
encoding and decoding, parsing, parameter extraction and modification.  All
functions are designed to be both fast and entirely vectorized.  It is
intended to be useful for people dealing with web-related datasets, such as
server-side logs, although may be useful for other situations involving large
sets of URLs.")
    (license license:expat)))

(define-public r-ggforce
  (package
    (name "r-ggforce")
    (version "0.3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggforce" version))
       (sha256
        (base32
         "04926cqrda6psvy2nzkkw4czwyxdp7fnxg76byp14v12kgd72lm0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gtable" ,r-gtable)
       ("r-mass" ,r-mass)
       ("r-polyclip" ,r-polyclip)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-rlang" ,r-rlang)
       ("r-scales" ,r-scales)
       ("r-tidyselect" ,r-tidyselect)
       ("r-tweenr" ,r-tweenr)
       ("r-withr" ,r-withr)))
    (home-page "https://ggforce.data-imaginist.com")
    (synopsis "Accelerating ggplot2")
    (description
     "The aim of the ggplot2 package is to aid in visual data investigations.
This focus has led to a lack of facilities for composing specialized plots.
Thi package aims to be a collection of mainly new statistics and geometries
that fills this gap.")
    (license license:expat)))

(define-public r-europepmc
  (package
    (name "r-europepmc")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "europepmc" version))
       (sha256
        (base32
         "1ngqs1sqzkbwv98dd5z4cxj8bnz41wyd0g060a2vpqi3s99s4i2h"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-plyr" ,r-plyr)
       ("r-progress" ,r-progress)
       ("r-purrr" ,r-purrr)
       ("r-urltools" ,r-urltools)
       ("r-xml2" ,r-xml2)))
    (home-page "https://github.com/ropensci/europepmc/")
    (synopsis "R Interface to the Europe PubMed Central RESTful Web Service")
    (description
     "This package provides an R Client for the
@url{https://europepmc.org/RestfulWebService,Europe PubMed Central RESTful Web
Service}.  It gives access to both metadata on life science literature and
open access full texts.  Europe PMC indexes all PubMed content and other
literature sources including Agricola, a bibliographic database of citations
to the agricultural literature, or Biological Patents.  In addition to
bibliographic metadata, the client allows users to fetch citations and
reference lists.  Links between life-science literature and other EBI
databases, including ENA, PDB or ChEMBL are also accessible.")
    (license license:gpl3)))

(define-public r-ggraph
  (package
    (name "r-ggraph")
    (version "2.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggraph" version))
       (sha256
        (base32
         "1ckq82hg52vr2wydkqv2wrppgjyvddd6bwqzrngqlm7j71xapjl0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-dplyr" ,r-dplyr)
       ("r-ggforce" ,r-ggforce)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-graphlayouts" ,r-graphlayouts)
       ("r-gtable" ,r-gtable)
       ("r-igraph" ,r-igraph)
       ("r-mass" ,r-mass)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)
       ("r-scales" ,r-scales)
       ("r-tidygraph" ,r-tidygraph)
       ("r-viridis" ,r-viridis)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://cran.r-project.org/web/packages/ggraph/")
    (synopsis "Implementation of grammar of graphics for graphs and networks")
    (description
     "The grammar of graphics as implemented in ggplot2 is a poor fit for
graph and network visualizations due to its reliance on tabular data input.
The ggraph package is an extension of the ggplot2 API tailored to graph
visualizations and provides the same flexible approach to building up plots
layer by layer.")
    (license license:gpl3)))

(define-public r-varselrf
  (package
    (name "r-varselrf")
    (version "0.7-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "varSelRF" version))
       (sha256
        (base32
         "0h49rl1j13yfh97rsfsyh9s2c4wajny4rzms2qw77d0cavxqg53i"))))
    (properties `((upstream-name . "varSelRF")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-randomforest" ,r-randomforest)))
    (home-page "https://www.ligarto.org/rdiaz/software/software")
    (synopsis "Variable selection using random forests")
    (description
     "This package provides tools for the variable selection from random
forests using both backwards variable elimination (for the selection of small
sets of non-redundant variables) and selection based on the importance
spectrum (somewhat similar to scree plots; for the selection of large,
potentially highly-correlated variables).  The main applications are in
high-dimensional data (e.g., microarray data, and other genomics and
proteomics applications).")
    (license license:gpl2+)))

(define-public r-pamr
  (package
    (name "r-pamr")
    (version "1.56.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pamr" version))
       (sha256
        (base32
         "0ycpgkk23y3zzkb42n2skcyl35ps1n7jmyzfj7pbxr3f6gr2grfh"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cluster" ,r-cluster)
       ("r-survival" ,r-survival)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/pamr/")
    (synopsis "Prediction Analysis for Microarrays")
    (description
     "This package provides some functions for sample classification in
microarrays.")
    (license license:gpl2)))

(define-public r-rda
  (package
    (name "r-rda")
    (version "1.0.2-2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rda" version))
       (sha256
        (base32
         "1y4fawslr3i6crjaxhsdb47kfsqkyszdx6avq3r5far5a4pvc639"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rda/")
    (synopsis "Shrunken centroids regularized discriminant analysis")
    (description
     "This package provides tools for shrunken centroids regularized
discriminant analysis for the purpose of classifying high dimensional data.")
    (license license:gpl2+)))

(define-public r-ggvis
  (package
    (name "r-ggvis")
    (version "0.4.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggvis" version))
       (sha256
        (base32
         "091i9f17912j8qcyxppjgwzjnyqj7769ixs9d2gjg6f2clskqdw2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-dplyr" ,r-dplyr)
       ("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-lazyeval" ,r-lazyeval)
       ("r-magrittr" ,r-magrittr)
       ("r-shiny" ,r-shiny)))
    (home-page "https://ggvis.rstudio.com/")
    (synopsis "Interactive grammar of graphics")
    (description
     "This package is a data visualization package for R providing an
implementation of an interactive grammar of graphics, taking the best parts of
ggplot2, combining them with the reactive framework of Shiny and drawing web
graphics using Vega.")
    (license license:gpl2)))

(define-public r-gbm
  (package
    (name "r-gbm")
    (version "2.1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gbm" version))
       (sha256
        (base32
         "0vs6ljaqhwwpgr8wlbhmm4v147rd82kl16rpaijqiylxcc8dxyq6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gridextra" ,r-gridextra)
       ("r-lattice" ,r-lattice)
       ("r-survival" ,r-survival)))
    (home-page "https://github.com/gbm-developers/gbm")
    (synopsis "Generalized boosted regression models")
    (description
     "This package is an implementation of extensions to Freund and Schapire's
AdaBoost algorithm and Friedman's gradient boosting machine.  It includes
regression methods for least squares, absolute loss, t-distribution loss,
quantile regression, logistic, multinomial logistic, Poisson, Cox proportional
hazards partial likelihood, AdaBoost exponential loss, Huberized hinge loss,
and Learning to Rank measures (LambdaMart).")
    (license license:gpl2+)))

(define-public r-threejs
  (package
    (name "r-threejs")
    (version "0.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "threejs" version))
       (sha256
        (base32
         "1711h351nzxfkbbdwvfzyhciyvi9c6wx3jq1g97lzcqgnb45kivn"))))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "js-jquery")
                         "htmlwidgets/lib/jquery/jquery.min.js")
                        (,(assoc-ref inputs "js-threejs-111")
                         "htmlwidgets/lib/threejs-111/three.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (delete-file target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-crosstalk" ,r-crosstalk)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-igraph" ,r-igraph)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("js-jquery"
        ,(origin
           (method url-fetch)
           (uri "https://code.jquery.com/jquery-1.12.4.js")
           (sha256
            (base32
             "0x9mrc1668icvhpwzvgafm8xm11x9lfai9nwr66aw6pjnpwkc3s3"))))
       ("js-threejs-111"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/mrdoob/three.js/r111/build/three.js")
           (sha256
            (base32
             "1cxdkw3plmlw1xvhbx5dm39gqczgzxip2dm887v6whhsxqxl9cky"))))))
    (home-page "https://bwlewis.github.io/rthreejs")
    (synopsis "Interactive 3D scatter plots, networks and globes")
    (description
     "Create interactive 3D scatter plots, network plots, and globes in R
using the three.js visualization library.")
    (license license:expat)))

(define-public r-mlbench
  (package
    (name "r-mlbench")
    (version "2.1-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mlbench" version))
       (sha256
        (base32
         "1rp035qxfgh5ail92zjh9jh57dj0b8babw3wsg29v8ricpal30bl"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/mlbench/")
    (synopsis "Machine learning benchmark problems")
    (description
     "This package provides a collection of artificial and real-world machine
learning benchmark problems, including, e.g., several data sets from the UCI
repository.")
    (license license:gpl2)))

(define-public r-mpm
  (package
    (name "r-mpm")
    (version "1.0-22")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mpm" version))
       (sha256
        (base32
         "0wijw8v0wmbfrda5564cmnp788qmlkk21yn5cp5qk8aprm9l1fnk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-kernsmooth" ,r-kernsmooth)
       ("r-mass" ,r-mass)))
    (home-page "http://mpm.r-forge.r-project.org")
    (synopsis "Multivariate projection methods")
    (description
     "This is a package for exploratory graphical analysis of multivariate
data, specifically gene expression data with different projection methods:
principal component analysis, correspondence analysis, spectral map
analysis.")
    (license license:gpl2+)))

(define-public r-png
  (package
    (name "r-png")
    (version "0.1-7")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "png" version))
              (sha256
               (base32
                "0g2mcp55lvvpx4kd3mn225mpbxqcq73wy5qx8b4lyf04iybgysg2"))))
    (build-system r-build-system)
    (inputs
     `(("libpng" ,libpng)
       ("zlib" ,zlib)))
    (home-page "https://www.rforge.net/png/")
    (synopsis "Read and write PNG images")
    (description
     "This package provides an easy and simple way to read, write and display
bitmap images stored in the PNG format.  It can read and write both files and
in-memory raw vectors.")
    ;; Any of these GPL versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-ggcorrplot
  (package
    (name "r-ggcorrplot")
    (version "0.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggcorrplot" version))
       (sha256
        (base32
         "0hi9lz121ya1l2lbm7rqlxg6fs6bvxck396dngnidrhl5fvqb41b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-reshape2" ,r-reshape2)))
    (home-page "http://www.sthda.com/english/wiki/ggcorrplot")
    (synopsis "Visualization of a correlation matrix using ggplot2")
    (description
     "The ggcorrplot package can be used to visualize easily a correlation
matrix using ggplot2.  It provides a solution for reordering the correlation
matrix and displays the significance level on the plot.  It also includes a
function for computing a matrix of correlation p-values.")
    (license license:gpl2)))

(define-public r-flexdashboard
  (package
    (name "r-flexdashboard")
    (version "0.5.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flexdashboard" version))
       (sha256
        (base32
         "0fy3nbrr67zqgd44r2mc850s5sp0hzfcw3zqs15m8kxzj1aw067x"))))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (srfi srfi-26)
                  (ice-9 popen)
                  (ice-9 textual-ports))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst"
               ;; Concatenate all components of prism.js
               (let ((contents (string-join
                                (map (lambda (name)
                                       (call-with-input-file
                                           (assoc-ref inputs name)
                                         get-string-all))
                                     (list "js-prism"
                                           "js-prism-r"
                                           "js-prism-line-numbers"))
                                "\n")))
                 (call-with-output-file "prism-src.js"
                   (cut display contents <>)))
               (call-with-values
                   (lambda ()
                     (unzip2
                      `(("www/stickytableheaders/jquery.stickytableheaders.js"
                         "www/stickytableheaders/jquery.stickytableheaders.min.js")
                        ("www/sly/sly.js"
                         "www/sly/sly.min.js")
                        ("prism-src.js"
                         "www/prism/prism.js")
                        (,(assoc-ref inputs "js-raphael")
                         "htmlwidgets/lib/raphael/raphael-2.1.4.min.js")
                        (,(assoc-ref inputs "js-featherlight")
                         "www/featherlight/featherlight.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (delete-file target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-shiny" ,r-shiny)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("js-raphael"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/DmitryBaranovskiy/raphael/v2.1.4/raphael.js")
           (sha256
            (base32
             "1h4c4akrgcj7wra9j1z1rv2406j0yf68y9c0wg8v7w9ibw2iwf1x"))))
       ("js-prism"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/PrismJS/prism/v1.16.0/prism.js")
           (sha256
            (base32
             "0gqa9irbp9k8p5r3d98cszajzhjnssnl43nrsc5aiy7ki52z500c"))))
       ("js-prism-r"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/PrismJS/prism/v1.16.0/components/prism-r.js")
           (sha256
            (base32
             "1x31glci7wdgr2305njy0bm2lncb0jyn0j1s2g72rqi29xid9aki"))))
       ("js-prism-line-numbers"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/PrismJS/prism/v1.16.0/plugins/line-numbers/prism-line-numbers.js")
           (sha256
            (base32
             "1543wgf3iynrilyb27jq8px3h5gvfz5xmdib5ik2ki400c1sl991"))))
       ("js-featherlight"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/noelboss/featherlight/1.3.4/src/featherlight.js")
           (sha256
            (base32
             "14kkhwzvp8rxq2mrck5i0xcm8v5rqwqhwnmncbng8h4qq42zx3sb"))))))
    (home-page "https://rmarkdown.rstudio.com/flexdashboard")
    (synopsis "R Markdown format for flexible dashboards")
    (description
     "This package provides an R Markdown format for converting an R Markdown
document to a grid-oriented dashboard.  The dashboard flexibly adapts the size
of its components to the containing web page.")
    (license license:expat)))

(define-public r-preseqr
  (package
    (name "r-preseqr")
    (version "4.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "preseqR" version))
       (sha256
        (base32
         "1g2rnnmi45649vpy6z45v5i3wxm54s138ajqrzwi3a5r7x3xnhq1"))))
    (properties `((upstream-name . "preseqR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-polynom" ,r-polynom)))
    (home-page "https://cran.r-project.org/web/packages/preseqR/")
    (synopsis "Predicting species accumulation curves")
    (description
     "This package can be used to predict the r-species accumulation
curve (r-SAC), which is the number of species represented at least r times as
a function of the sampling effort.  When r = 1, the curve is known as the
species accumulation curve, or the library complexity curve in high-throughput
genomic sequencing.  The package includes both parametric and nonparametric
methods, as described by Deng C, et al. (2018).")
    (license license:gpl3)))

(define-public r-mapplots
  (package
    (name "r-mapplots")
    (version "1.5.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mapplots" version))
       (sha256
        (base32
         "18s2y66f8vi8g2r8a25zbgp2xm079r8v8qxv0w71h8krycs6vs9p"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/mapplots/")
    (synopsis "Data visualization on maps")
    (description
     "This package helps you create simple maps; add sub-plots like pie plots
to a map or any other plot; format, plot and export gridded data.  The package
was developed for displaying fisheries data but most functions can be used for
more generic data visualisation.")
    (license license:gpl2+)))

(define-public r-pmcmr
  (package
    (name "r-pmcmr")
    (version "4.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "PMCMR" version))
       (sha256
        (base32
         "09bvdj2h1086r2cgy3myrhlylplxxlliv8nwx09c8kb1vn02i2ij"))))
    (properties `((upstream-name . "PMCMR")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/PMCMR/")
    (synopsis "Calculate pairwise multiple comparisons of mean rank sums")
    (description
     "This is a deprecated package for calculating pairwise multiple
comparisons of mean rank sums.  This package is superseded by the novel
PMCMRplus package.  The PMCMR package is no longer maintained, but kept for
compatibility of dependent packages for some time.")
    (license license:gpl3+)))

(define-public r-downloader
  (package
    (name "r-downloader")
    (version "0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "downloader" version))
       (sha256
        (base32
         "1axggnsc27zzgr7snf41j3zd1vp3nfpmq4zj4d01axc709dyg40q"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)))
    (home-page "https://github.com/wch/downloader")
    (synopsis "Download files over HTTP and HTTPS")
    (description
     "This package provides a wrapper for the @code{download.file} function,
making it possible to download files over HTTPS across platforms.  The
@code{RCurl} package provides this functionality (and much more) but has
external dependencies.  This package has is implemented purely in R.")
    (license license:gpl2)))

(define-public r-rex
  (package
    (name "r-rex")
    (version "1.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rex" version))
       (sha256
        (base32
         "0alsadgjgass3wr8y5d247j12qqzg454sc84vpskclrkmz778g5x"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lazyeval" ,r-lazyeval)
       ("r-magrittr" ,r-magrittr)))
    (home-page "https://github.com/kevinushey/rex")
    (synopsis "Friendly regular expressions")
    (description
     "This package provides a friendly interface for the construction of
regular expressions.  Regular expressions are a very powerful feature, however
they are often difficult to interpret.  Rex allows you to build complex
regular expressions from human readable expressions")
    (license license:expat)))

(define-public r-xmlparsedata
  (package
    (name "r-xmlparsedata")
    (version "1.0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xmlparsedata" version))
       (sha256
        (base32
         "0gjr3l5z5dp276lchr2649as1rkj56d2mlvbr66yg393zzw50lsh"))))
    (properties `((upstream-name . "xmlparsedata")))
    (build-system r-build-system)
    (home-page "https://github.com/r-lib/xmlparsedata#readme")
    (synopsis "Parse data of @code{R} code as an @code{XML} tree")
    (description
     "This package provides tools to convert the output of
@code{utils::getParseData()} to an @code{XML} tree, that one can search via
@code{XPath}, and is easier to manipulate in general.")
    (license license:expat)))

(define-public r-cyclocomp
  (package
    (name "r-cyclocomp")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cyclocomp" version))
       (sha256
        (base32
         "0gky3svk02wiajw7nfjh30684h3qxili4bvsab0m7b6cggw6bgyd"))))
    (properties `((upstream-name . "cyclocomp")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-callr" ,r-callr)
       ("r-crayon" ,r-crayon)
       ("r-desc" ,r-desc)
       ("r-remotes" ,r-remotes)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/MangoTheCat/cyclocomp")
    (synopsis "Cyclomatic complexity of R code")
    (description
     "Cyclomatic complexity is a software metric, used to indicate the
complexity of a program.  It is a quantitative measure of the number of
linearly independent paths through a program's source code.  This package
provides tools to compute this metric.")
    (license license:expat)))

(define-public r-lintr
  (package
    (name "r-lintr")
    (version "2.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lintr" version))
       (sha256
        (base32
         "14yfh641afg6griaadbdciyr3k94fl55s055qwzghgk5gdsj61zy"))))
    (properties `((upstream-name . "lintr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-codetools" ,r-codetools)
       ("r-crayon" ,r-crayon)
       ("r-cyclocomp" ,r-cyclocomp)
       ("r-digest" ,r-digest)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-rex" ,r-rex)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-testthat" ,r-testthat)
       ("r-xml2" ,r-xml2)
       ("r-xmlparsedata" ,r-xmlparsedata)))
    (home-page "https://github.com/jimhester/lintr")
    (synopsis "Linter for R code")
    (description "This package checks adherence to a given style, syntax
errors and possible semantic issues.  It supports on the fly checking of R
code edited with @code{RStudio IDE}, @code{Emacs} and @code{Vim}.")
    (license license:expat)))

(define-public r-sctransform
  (package
    (name "r-sctransform")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sctransform" version))
       (sha256
        (base32
         "07v3lzccsrkh1glfxd1q20r8f8gl9ls5az0s1dvxm4vcls0hlhyn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-future-apply" ,r-future-apply)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-reshape2" ,r-reshape2)))
    (home-page "https://github.com/ChristophH/sctransform")
    (synopsis "Variance stabilizing transformations for Single Cell UMI Data")
    (description
     "This package provides a normalization method for single-cell UMI count
data using a variance stabilizing transformation.  The transformation is based
on a negative binomial regression model with regularized parameters.  As part
of the same regression framework, this package also provides functions for
batch correction, and data correction.")
    (license license:gpl3)))

(define-public r-styler
  (package
    (name "r-styler")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "styler" version))
       (sha256
        (base32
         "1waglhsy2c53qjgd2qhlzda3z0lbzbwx9fkrfhac41y6h91mgkrz"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-backports" ,r-backports)
       ("r-cli" ,r-cli)
       ("r-magrittr" ,r-magrittr)
       ("r-purrr" ,r-purrr)
       ("r-r-cache" ,r-r-cache)
       ("r-rematch2" ,r-rematch2)
       ("r-rlang" ,r-rlang)
       ("r-rprojroot" ,r-rprojroot)
       ("r-tibble" ,r-tibble)
       ("r-withr" ,r-withr)
       ("r-xfun" ,r-xfun)))
    (home-page "https://github.com/r-lib/styler")
    (synopsis "Non-invasive pretty printing of R code")
    (description
     "This is a package for pretty-printing R code without changing the user's
formatting intent.")
    (license license:gpl3)))

(define-public r-scrime
  (package
    (name "r-scrime")
    (version "1.3.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "scrime" version))
       (sha256
        (base32
         "0y2mh9fsffjf3i15bafpasa17z99c1s75r8g6h4hgcwfgpjx75sx"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/scrime/")
    (synopsis "Analysis of high-dimensional categorical data such as SNP data")
    (description
     "This package provides tools for the analysis of high-dimensional data
developed/implemented at the group \"Statistical Complexity Reduction In
Molecular Epidemiology\" (SCRIME).  The main focus is on SNP data, but most of
the functions can also be applied to other types of categorical data.")
    (license license:gpl2)))

(define-public r-pbmcapply
  (package
    (name "r-pbmcapply")
    (version "1.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pbmcapply" version))
       (sha256
        (base32
         "0i58gcqpnbyvc448qfgm45b7rpbmrnagsvk1h1hsqchbbicfslnz"))))
    (build-system r-build-system)
    (home-page "https://github.com/kvnkuang/pbmcapply")
    (synopsis "Track the progress of apply procedures with a progress bar")
    (description
     "This light-weight package helps you track and visualize the progress of
parallel versions of vectorized R functions of the @code{mc*apply} family.")
    (license license:expat)))

(define-public r-blme
  (package
    (name "r-blme")
    (version "1.0-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "blme" version))
       (sha256
        (base32
         "1ca2b0248k0fj3lczn9shfjplz1sl4ay4v6djldizp2ch2vwdgy2"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-lme4" ,r-lme4)))
    (home-page "https://github.com/vdorie/blme")
    (synopsis "Bayesian linear mixed-effects models")
    (description
     "This package provides tools for maximum a posteriori estimation for
linear and generalized linear mixed-effects models in a Bayesian setting.  It
extends the lme4 package.")
    (license license:gpl2+)))

(define-public r-batchtools
  (package
    (name "r-batchtools")
    (version "0.9.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "batchtools" version))
       (sha256
        (base32
         "02bwfinwgn5nl638997javig61jmr0ci0qybmprz13jnvmam1yns"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-backports" ,r-backports)
       ("r-base64url" ,r-base64url)
       ("r-brew" ,r-brew)
       ("r-checkmate" ,r-checkmate)
       ("r-data-table" ,r-data-table)
       ("r-digest" ,r-digest)
       ("r-fs" ,r-fs)
       ("r-progress" ,r-progress)
       ("r-r6" ,r-r6)
       ("r-rappdirs" ,r-rappdirs)
       ("r-stringi" ,r-stringi)
       ("r-withr" ,r-withr)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/mllg/batchtools")
    (synopsis "Tools for computation on batch systems")
    (description
     "As a successor of the packages BatchJobs and BatchExperiments, this
package provides a parallel implementation of the Map function for high
performance computing systems managed by various schedulers.  A multicore and
socket mode allow the parallelization on a local machines, and multiple
machines can be hooked up via SSH to create a makeshift cluster.  Moreover,
the package provides an abstraction mechanism to define large-scale computer
experiments in a well-organized and reproducible way.")
    (license license:lgpl3)))

(define-public r-clue
  (package
    (name "r-clue")
    (version "0.3-57")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "clue" version))
       (sha256
        (base32
         "05rdcahawxlxci3fjxihjvvh33wqpxw50sx015165ab4nh3rsdkf"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-cluster" ,r-cluster)))
    (home-page "https://cran.r-project.org/web/packages/clue/")
    (synopsis "Tools for analyzing cluster ensembles")
    (description "Cluster ensembles are collections of individual solutions to
a given clustering problem which are useful or necessary to consider in a wide
range of applications.  This R package provides an extensible computational
environment for creating and analyzing cluster ensembles, with basic data
structures for representing partitions and hierarchies, and facilities for
computing on them, including methods for measuring proximity and obtaining
consensus and secondary clusterings.")
    (license license:gpl2)))

(define-public r-sitmo
  (package
    (name "r-sitmo")
    (version "2.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sitmo" version))
       (sha256
        (base32
         "0apdhwy3kxs39agsbvx5vn3xsgb22bf3jrwmr2cmqk9kmxbx740c"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/coatless/sitmo/")
    (synopsis "Parallel pseudo random number generator header files")
    (description
     "This package provides two high quality and fast PPRNGs that may be used
in an OpenMP parallel environment.  In addition, there is a generator for one
dimensional low-discrepancy sequence.")
    (license license:expat)))

(define-public r-dqrng
  (package
    (name "r-dqrng")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dqrng" version))
       (sha256
        (base32
         "0rp8q5zijlvaqmpnkwr314w9w40sj4fz7sqsdgsffcfvn42w2jg1"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-rcpp" ,r-rcpp)
       ("r-sitmo" ,r-sitmo)))
    (home-page "https://www.daqana.org/dqrng")
    (synopsis "Fast pseudo random number generators")
    (description
     "Several fast random number generators are provided as C++ header-only
libraries: the PCG family as well as Xoroshiro128+ and Xoshiro256+.
Additionally, fast functions for generating random numbers according to a
uniform, normal and exponential distribution are included.  The latter two use
the Ziggurat algorithm originally proposed by Marsaglia and Tsang.  These
functions are exported to R and as a C++ interface and are enabled for use
with the default 64 bit generator from the PCG family, Xoroshiro128+ and
Xoshiro256+ as well as the 64 bit version of the 20 rounds Threefry
engine (Salmon et al., 2011) as provided by the package @code{sitmo}.")
    ;; This package includes code under CC0 and Apache 2.0 or Expat, but as a
    ;; whole is distributed under the terms of the AGPL 3.
    (license license:agpl3)))

(define-public r-dalex
  (package
    (name "r-dalex")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "DALEX" version))
       (sha256
        (base32
         "1jbyn57vn6d281a5y15h5d8ljin8cdb9lr7lbgggc950blyfv4g0"))))
    (properties `((upstream-name . "DALEX")))
    (build-system r-build-system)
    (propagated-inputs `(("r-ggplot2" ,r-ggplot2)))
    (home-page "https://pbiecek.github.io/DALEX/")
    (synopsis "Descriptive machine learning explanations")
    (description
     "Machine Learning models are widely used and have various applications in
classification or regression.  Models created with boosting, bagging, stacking
or similar techniques are often used due to their high performance, but such
black-box models usually lack interpretability.  The DALEX package contains
various explainers that help to understand the link between input variables
and model output.")
    ;; Any version of the GPL
    (license license:gpl3+)))

(define-public r-enrichr
  (package
    (name "r-enrichr")
    (version "2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "enrichR" version))
       (sha256
        (base32
         "0ymhzs9d2wl0s9rvbqc1hqb78mlzwhlc7mmijpfqkm5r720pf6m1"))))
    (properties `((upstream-name . "enrichR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-httr" ,r-httr)
       ("r-rjson" ,r-rjson)))
    (home-page "https://cran.r-project.org/web/packages/enrichR/")
    (synopsis "R Interface to Enrichr database for analyzing gene sets")
    (description
     "This package provides an R interface to all Enrichr databases, a
web-based tool for analyzing gene sets and returns any enrichment of common
annotated biological functions.")
    (license license:gpl2+)))

(define-public r-plot3d
  (package
    (name "r-plot3d")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "plot3D" version))
       (sha256
        (base32
         "1jfzndnlci9a975qbcv66jiy2l46hs3f2049654x4jp3i4kyrr5r"))))
    (properties `((upstream-name . "plot3D")))
    (build-system r-build-system)
    (propagated-inputs `(("r-misc3d" ,r-misc3d)))
    (home-page "https://cran.r-project.org/web/packages/plot3D")
    (synopsis "Plot multi-dimensional data")
    (description
     "This package provides functions for viewing 2D and 3D data, including
perspective plots, slice plots, surface plots, scatter plots, etc.  It
includes data sets from oceanography.")
    (license license:gpl3+)))

(define-public r-ggfortify
  (package
    (name "r-ggfortify")
    (version "0.4.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggfortify" version))
       (sha256
        (base32
         "1p6knrbyaynaqwd939w09hpf1zz1gn95cb46sfgppl8l98krb2h5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-scales" ,r-scales)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/sinhrks/ggfortify")
    (synopsis "Data visualization tools for statistical analysis results")
    (description
     "This package provides unified plotting tools for statistics commonly
used, such as GLM, time series, PCA families, clustering and survival
analysis.  The package offers a single plotting interface for these analysis
results and plots in a unified style using the @code{ggplot2} package.")
    (license license:gpl2)))

(define-public r-refmanager
  (package
    (name "r-refmanager")
    (version "1.2.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RefManageR" version))
       (sha256
        (base32
         "1hfxa1qacfryk36mpaqdhdgws5jwxiyy489ikd3wa18bp1wz8dkp"))))
    (properties `((upstream-name . "RefManageR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bibtex" ,r-bibtex)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-lubridate" ,r-lubridate)
       ("r-plyr" ,r-plyr)
       ("r-stringr" ,r-stringr)
       ("r-xml2" ,r-xml2)))
    (home-page "https://github.com/ropensci/RefManageR/")
    (synopsis "Straightforward BibTeX and BibLaTeX bibliography management")
    (description
     "This package provides tools for importing and working with bibliographic
references.  It greatly enhances the @code{bibentry} class by providing a
class @code{BibEntry} which stores BibTeX and BibLaTeX references, supports
UTF-8 encoding, and can be easily searched by any field, by date ranges, and
by various formats for name lists (author by last names, translator by full
names, etc.).  Entries can be updated, combined, sorted, printed in a number
of styles, and exported.  BibTeX and BibLaTeX @code{.bib} files can be read
into R and converted to @code{BibEntry} objects.")
    ;; Any of these licenses may be picked.
    (license (list license:gpl2 license:gpl3 license:bsd-3))))

(define-public r-citr
  (package
    (name "r-citr")
    (version "0.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "citr" version))
       (sha256
        (base32
         "1qbarvafjb8jgkrnrhh6jw7mcglmjwf7dpdiibxf39jkmlhf7las"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-curl" ,r-curl)
       ("r-httr" ,r-httr)
       ("r-miniui" ,r-miniui)
       ("r-refmanager" ,r-refmanager)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-shiny" ,r-shiny)
       ("r-shinyjs" ,r-shinyjs)
       ("r-yaml" ,r-yaml)))
    (home-page "https://github.com/crsh/citr")
    (synopsis "RStudio add-in to insert Markdown citations")
    (description
     "This package provides functions and an RStudio add-in that search a
BibTeX or BibLaTeX file to create and insert formatted Markdown citations into
the current document.")
    (license license:expat)))

(define-public r-xgboost
  (package
    (name "r-xgboost")
    (version "1.0.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xgboost" version))
       (sha256
        (base32
         "1ld2w51c5fy3bl0kvjn1iplffc4lmin9s9zz5xx7xsm44d6j6kzd"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-magrittr" ,r-magrittr)
       ("r-matrix" ,r-matrix)
       ("r-stringi" ,r-stringi)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/dmlc/xgboost")
    (synopsis "Extreme gradient boosting")
    (description
     "This package provides an R interface to Extreme Gradient Boosting, which
is an efficient implementation of the gradient boosting framework from Chen
and Guestrin (2016).  The package includes efficient linear model solver and
tree learning algorithms.  The package can automatically do parallel
computation on a single machine.  It supports various objective functions,
including regression, classification and ranking.  The package is made to be
extensible, so that users are also allowed to define their own objectives
easily.")
    (license license:asl2.0)))

(define-public r-umap
  (package
    (name "r-umap")
    (version "0.2.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "umap" version))
       (sha256
        (base32
         "0qp8zbh6fn8kn6q2h2lyjgmq3pr6gqwsd8ymqx25px13zjhxch9d"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-openssl" ,r-openssl)
       ("r-rcpp" ,r-rcpp)
       ("r-reticulate" ,r-reticulate)
       ("r-rspectra" ,r-rspectra)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/tkonopka/umap")
    (synopsis "Uniform manifold approximation and projection")
    (description
     "Uniform manifold approximation and projection is a technique for
dimension reduction.  This package provides an interface to the UMAP algorithm
in R, including a translation of the original algorithm into R.")
    (license license:expat)))

(define-public r-uwot
  (package
    (name "r-uwot")
    (version "0.1.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "uwot" version))
       (sha256
        (base32
         "1jzh8r1h6f7pw7pb1fr32vn6ai9g10s56ahkq0vi77iznihy1rpd"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dqrng" ,r-dqrng)
       ("r-fnn" ,r-fnn)
       ("r-irlba" ,r-irlba)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppannoy" ,r-rcppannoy)
       ("r-rcppprogress" ,r-rcppprogress)
       ("r-rspectra" ,r-rspectra)))
    (home-page "https://github.com/jlmelville/uwot")
    (synopsis "Uniform manifold approximation and projection")
    (description
     "This package provides an implementation of the Uniform Manifold
Approximation and Projection dimensionality reduction by McInnes et
al. (2018).  It also provides means to transform new data and to carry out
supervised dimensionality reduction.  An implementation of the related
LargeVis method of Tang et al. (2016) is also provided.")
    (license license:gpl3)))

(define-public r-kableextra
  (package
    (name "r-kableextra")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kableExtra" version))
       (sha256
        (base32
         "1nicvw06xsf3a1f5c10mih07b76m2v5s5h165vmz0qx6n1a3492i"))))
    (properties `((upstream-name . "kableExtra")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-glue" ,r-glue)
       ("r-htmltools" ,r-htmltools)
       ("r-knitr" ,r-knitr)
       ("r-magrittr" ,r-magrittr)
       ("r-readr" ,r-readr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-rvest" ,r-rvest)
       ("r-scales" ,r-scales)
       ("r-stringr" ,r-stringr)
       ("r-viridislite" ,r-viridislite)
       ("r-webshot" ,r-webshot)
       ("r-xml2" ,r-xml2)))
    (home-page "https://haozhu233.github.io/kableExtra/")
    (synopsis "Construct complex tables with pipe syntax")
    (description
     "Build complex HTML or LaTeX tables using @code{kable()} from
@code{knitr} and the piping syntax from @code{magrittr}.  The function
@code{kable()} is a light weight table generator coming from @code{knitr}.
This package simplifies the way to manipulate the HTML or LaTeX codes
generated by @code{kable()} and allows users to construct complex tables and
customize styles using a readable syntax.")
    (license license:expat)))

(define-public r-glasso
  (package
    (name "r-glasso")
    (version "1.11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "glasso" version))
       (sha256
        (base32 "02p3612rpydk195n2qr77lp1j2w8zsw1ckkk98c8angm4r5q8dsc"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://statweb.stanford.edu/~tibs/glasso/")
    (synopsis "Graphical Lasso: estimation of Gaussian graphical models")
    (description
     "This is a package for estimation of a sparse inverse covariance matrix
using a lasso (L1) penalty.  Facilities are provided for estimates along a
path of values for the regularization parameter.")
    (license license:gpl2)))

(define-public r-rhpcblasctl
  (package
    (name "r-rhpcblasctl")
    (version "0.20-17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RhpcBLASctl" version))
       (sha256
        (base32
         "0iwc06blr5sx7rylwczi2jrha8sk8qs0jklflwpidl0zj1jxdggp"))))
    (properties `((upstream-name . "RhpcBLASctl")))
    (build-system r-build-system)
    (home-page "https://prs.ism.ac.jp/~nakama/Rhpc/")
    (synopsis "Control the number of threads on BLAS")
    (description
     "This package allows you to control the number of threads the BLAS
library uses.  It is also possible to control the number of threads in
OpenMP.")
    (license license:agpl3+)))

(define-public r-lda
  (package
    (name "r-lda")
    (version "1.4.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lda" version))
       (sha256
        (base32
         "03r4h5kgr8mfy44p66mfj5bp4k00g8zh4a1mhn46jw14pkhs21jn"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/lda/")
    (synopsis "Collapsed Gibbs sampling methods for topic models")
    (description
     "This package implements @dfn{latent Dirichlet allocation} (LDA) and
related models.  This includes (but is not limited to) sLDA, corrLDA, and the
mixed-membership stochastic blockmodel.  Inference for all of these models is
implemented via a fast collapsed Gibbs sampler written in C.  Utility
functions for reading/writing data typically used in topic models, as well as
tools for examining posterior distributions are also included.")
    ;; Any version of the LGPL
    (license license:lgpl3+)))

(define-public r-rann-l1
  (package
    (name "r-rann-l1")
    (version "2.5.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RANN.L1" version))
       (sha256
        (base32
         "1hanh3my84mdr5wy6b89fawqzfc184vff1y65wy4l5ld9qza1n44"))))
    (properties `((upstream-name . "RANN.L1")))
    (build-system r-build-system)
    (home-page "https://github.com/jefferis/RANN/tree/master-L1")
    (synopsis "Fast nearest neighbour search using L1 metric")
    (description
     "This package provides tools to find the k nearest neighbours for every
point in a given dataset in O(N log N) time using Arya and Mount's ANN
library.  There is support for approximate as well as exact searches, fixed
radius searches and @code{bd} as well as @code{kd} trees.  The distance is
computed using the L1 (Manhattan, taxicab) metric.")
    (license license:gpl3+)))

(define-public r-leiden
  (package
    (name "r-leiden")
    (version "0.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "leiden" version))
       (sha256
        (base32
         "1hh6bmbz6cpqwl4i94gxylgv9x92zbqdg81r8r4ymfy8c70f3df2"))))
    (properties `((upstream-name . "leiden")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)
       ("r-matrix" ,r-matrix)
       ("r-reticulate" ,r-reticulate)))
    (home-page "https://github.com/TomKellyGenetics/leiden")
    (synopsis "R implementation of Leiden clustering algorithm")
    (description
     "This package implements the Python @code{leidenalg} module to be called
in R.  It enables clustering using the Leiden algorithm for partitioning a
graph into communities.  See also Traag et al (2018) \"From Louvain to Leiden:
guaranteeing well-connected communities.\" <arXiv:1810.08473>.")
    (license license:gpl3)))

(define-public r-patchwork
  (package
    (name "r-patchwork")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "patchwork" version))
       (sha256
        (base32
         "0qrwbcswh7ylrmghi17k6wk7w51cz6mcmvcyyd41hy3m2ywmkywb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gtable" ,r-gtable)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/thomasp85/patchwork")
    (synopsis "Compose ggplot2 plots")
    (description
     "The @code{ggplot2} package provides a strong API for sequentially
building up a plot, but does not concern itself with composition of multiple
plots.  Patchwork is a package that expands the API to allow for arbitrarily
complex composition of plots by providing mathmatical operators for combining
multiple plots.")
    (license license:expat)))

(define-public r-liger
  (package
    (name "r-liger")
    (version "0.4.2")
    (source
     (origin
       (method git-fetch)
       (uri (git-reference
             (url "https://github.com/MacoskoLab/liger.git")
             (commit (string-append "v" version))))
       (file-name (git-file-name name version))
       (sha256
        (base32
         "16dzwwcpw6n78pxlc5w3kraigki35ix7zhd2cbx5f3y60bbkhlmx"))
       (modules '((guix build utils)))
       (snippet
        '(begin
           (delete-file "inst/java/ModularityOptimizer.jar")
           #t))))
    (build-system r-build-system)
    (arguments
     `(#:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'build-java-part
           (lambda* (#:key inputs #:allow-other-keys)
             (invoke "unzip" (assoc-ref inputs "optimizer-src"))
             (for-each (lambda (file) (invoke "javac" file))
                       (find-files "." "\\.java$"))
             (apply invoke "jar" "cf" "inst/java/ModularityOptimizer.jar"
                    (find-files "." "\\.class$"))
             #t)))))
    (propagated-inputs
     `(("r-cowplot" ,r-cowplot)
       ("r-dosnow" ,r-dosnow)
       ("r-dplyr" ,r-dplyr)
       ("r-fnn" ,r-fnn)
       ("r-foreach" ,r-foreach)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-hmisc" ,r-hmisc)
       ("r-ica" ,r-ica)
       ("r-irlba" ,r-irlba)
       ("r-matrix" ,r-matrix)
       ("r-mclust" ,r-mclust)
       ("r-patchwork" ,r-patchwork)
       ("r-plyr" ,r-plyr)
       ("r-rann-l1" ,r-rann-l1)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-riverplot" ,r-riverplot)
       ("r-rtsne" ,r-rtsne)
       ("r-snow" ,r-snow)))
    (native-inputs
     `(("jdk" ,icedtea "jdk")
       ;; See https://github.com/MacoskoLab/liger/issues/96
       ;; The optimizer is released under the Expat license.
       ("optimizer-src"
        ,(origin
           (method url-fetch)
           (uri "http://www.ludowaltman.nl/slm/modularity_optimizer_source.zip")
           (sha256
            (base32
             "01hmm6sapcmldvayknqx2w4cav3qv71mwwkdkwj4qgq6dss09g18"))))
       ("unzip" ,unzip)
       ("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://github.com/MacoskoLab/liger")
    (synopsis "Integrate and analyze multiple single-cell datasets")
    (description
     "LIGER is a package for integrating and analyzing multiple single-cell
datasets, developed and maintained by the Macosko lab.  It relies on
integrative non-negative matrix factorization to identify shared and
dataset-specific factors.")
    (license license:gpl3)))

(define-public r-harmony
  (package
    (name "r-harmony")
    (version "0.1")
    (source
     (origin
       (method git-fetch)
       (uri (git-reference
             (url "https://github.com/immunogenomics/harmony")
             (commit version)))
       (file-name (git-file-name name version))
       (sha256
        (base32
         "05r401q09rbr6fqhb9mbd95082cjdi3nag1cv6zn96xkr0f6imq9"))
       (modules '((guix build utils)))
       (snippet
        '(begin
           (for-each delete-file '("config.status" "configure"))
           #t))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cowplot" ,r-cowplot)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-irlba" ,r-irlba)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rcppprogress" ,r-rcppprogress)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (native-inputs
     `(("autoconf" ,autoconf)))
    (home-page "https://github.com/immunogenomics/harmony")
    (synopsis "Integration of single cell sequencing data")
    (description
     "This package provides an implementation of the Harmony algorithm for
single cell integration, described in Korsunsky et al
@url{doi.org/10.1101/461954}.  The package includes a standalone Harmony
function and interfaces to external frameworks.")
    (license license:gpl3)))

(define-public r-covr
  (package
    (name "r-covr")
    (version "3.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "covr" version))
       (sha256
        (base32 "1pvr95h7jg9hqq1qq1cccy323pkxldrwafl08151cc410499k4fb"))))
    (properties `((upstream-name . "covr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-crayon" ,r-crayon)
       ("r-digest" ,r-digest)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-rex" ,r-rex)
       ("r-withr" ,r-withr)
       ("r-yaml" ,r-yaml)))
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://github.com/r-lib/covr")
    (synopsis "Test coverage for R packages")
    (description
     "Thisp package enables you to track and report code coverage for your
package and (optionally) upload the results to a coverage service.  Code
coverage is a measure of the amount of code being exercised by a set of tests.
It is an indirect measure of test quality and completeness.  This package is
compatible with any testing methodology or framework and tracks coverage of
both R code and compiled C/C++/FORTRAN code.")
    (license license:gpl3)))

(define-public r-systemfonts
  (package
    (name "r-systemfonts")
    (version "0.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "systemfonts" version))
       (sha256
        (base32
         "0m0ljid683xcam2f14x7k2zv1yx4npac38a3gfv11vhxfbnpgp0z"))))
    (properties `((upstream-name . "systemfonts")))
    (build-system r-build-system)
    (inputs
     `(("fontconfig" ,fontconfig)
       ("freetype" ,freetype)
       ("zlib" ,zlib)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/r-lib/systemfonts")
    (synopsis "System native font finding")
    (description
     "This package provides system native access to the font catalogue.  As
font handling varies between systems it is difficult to correctly locate
installed fonts across different operating systems.  The 'systemfonts' package
provides bindings to the native libraries for finding font files that can then
be used further by e.g. graphic devices.")
    (license license:expat)))

(define-public r-graphlayouts
  (package
    (name "r-graphlayouts")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "graphlayouts" version))
       (sha256
        (base32
         "1la016m37kp79zk8p1yx9kaha8y6d4w52w39h0mzv1mfsi6d75w0"))))
    (properties `((upstream-name . "graphlayouts")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "https://github.com/schochastics/graphlayouts")
    (synopsis "Additional layout algorithms for network visualizations")
    (description
     "This package provides several layout algorithms to visualize networks
which are not part of the igraph library.  Most are based on the concept of
stress majorization by Gansner et al. (2004)
<doi:10.1007/978-3-540-31843-9_25>.  Some more specific algorithms allow to
emphasize hidden group structures in networks or focus on specific nodes.")
    (license license:expat)))

(define-public r-tidygraph
  (package
    (name "r-tidygraph")
    (version "1.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tidygraph" version))
       (sha256
        (base32
         "1zpsarm74afbc7p5dlyb0whc09670qdcddw1ckb25cfc9hfh0hjn"))))
    (properties `((upstream-name . "tidygraph")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-igraph" ,r-igraph)
       ("r-magrittr" ,r-magrittr)
       ("r-pillar" ,r-pillar)
       ("r-r6" ,r-r6)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/thomasp85/tidygraph")
    (synopsis "Tidy API for graph manipulation")
    (description
     "This package provides a graph implementation that can be thought of as
two tidy data frames describing node and edge data respectively.  It provides
an approach to manipulate these two virtual data frames using the API defined
in the @code{dplyr} package, and it also provides tidy interfaces to a lot of
common graph algorithms.")
    (license license:expat)))

(define-public r-soupx
  (let ((commit "a3354be76fb52fd795be6ddf163cf056c05c6cb8")
        (revision "1"))
    (package
      (name "r-soupx")
      (version (git-version "0.3.1" revision commit))
      (source
       (origin
         (method git-fetch)
         (uri (git-reference
               (url "https://github.com/constantAmateur/SoupX")
               (commit commit)))
         (file-name (git-file-name name version))
         (sha256
          (base32
           "1zmlyzrl0fz6l79gn2wswid670p88mm3y292is89sa5p3h7frr99"))))
      (properties `((upstream-name . "SoupX")))
      (build-system r-build-system)
      (propagated-inputs
       `(("r-ggplot2" ,r-ggplot2)
         ("r-matrix" ,r-matrix)
         ("r-seurat" ,r-seurat)))
      (home-page "https://github.com/constantAmateur/SoupX")
      (synopsis "Single cell mRNA Soup eXterminator")
      (description
       "This package provides a package for quantifying, profiling and
removing cell free mRNA contamination (the \"soup\") from droplet based single
cell RNA-seq experiments.")
      (license license:gpl2))))

(define-public r-assertr
  (package
    (name "r-assertr")
    (version "2.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertr" version))
       (sha256
        (base32
         "1x868pd4dac1c7b1q5390wqh2f6s50km8nqcpim3nxcj2l4qkqdb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-mass" ,r-mass)
       ("r-rlang" ,r-rlang)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))           ; needed for vignette
    (home-page "https://github.com/ropensci/assertr")
    (synopsis "Assertive programming for R analysis pipelines")
    (description
     "This package provides functionality to assert conditions that have to be
met so that errors in data used in analysis pipelines can fail quickly.  It is
similar to @code{stopifnot()} but more powerful, friendly, and easier for use
in pipelines.")
    (license license:expat)))

(define-public r-parameters
  (package
    (name "r-parameters")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "parameters" version))
       (sha256
        (base32
         "0zin3ikc013hc713n5zs0dbhc3m4nfw1vhc3924z0mrww8r241xn"))))
    (properties `((upstream-name . "parameters")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayestestr" ,r-bayestestr)
       ("r-insight" ,r-insight)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://cran.r-project.org/web/packages/parameters")
    (synopsis "Processing of model parameters")
    (description
     "This package provides utilities for processing the parameters of various
statistical models.  Beyond computing p values, CIs, and other indices for a
wide variety of models, this package implements features like standardization
or bootstrapping of parameters and models, feature reduction (feature
extraction and variable selection) as well as conversion between indices of
effect size.")
    (license license:gpl3)))

(define-public r-rgdal
  (package
    (name "r-rgdal")
    (version "1.4-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rgdal" version))
       (sha256
        (base32 "1jd691amf3ghznq5im15gvhl6v6k25klpl75m4ngrqf9xlxaa3as"))))
    (properties `((upstream-name . "rgdal")))
    (build-system r-build-system)
    (inputs
     `(("gdal" ,gdal)
       ("proj.4" ,proj.4)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-sp" ,r-sp)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "http://rgdal.r-forge.r-project.org")
    (synopsis "Bindings for the Geospatial Data Abstraction Library")
    (description
     "This package provides bindings to the Geospatial Data Abstraction
Library (GDAL) and access to projection/transformation operations from the
PROJ.4 library.")
    (license license:gpl2+)))

(define-public r-insol
  (package
    (name "r-insol")
    (version "1.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "insol" version))
       (sha256
        (base32
         "1d2vqmbp94ff80mfkmq4a8y12r6ryym8hh1568ip9qbn7snc64v1"))))
    (properties `((upstream-name . "insol")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-raster" ,r-raster)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://meteoexploration.com/R/insol/index.html")
    (synopsis "Tools for calculating solar radiation")
    (description
     "This package provides functions to compute insolation on tilted
surfaces, computes atmospheric transmittance and related parameters such as:
Earth radius vector, declination, sunset and sunrise, daylength, equation of
time, vector in the direction of the sun, vector normal to surface, and some
atmospheric physics.")
    (license license:gpl2+)))

(define-public r-lifecycle
  (package
    (name "r-lifecycle")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lifecycle" version))
       (sha256
        (base32
         "0912865c6675fsblrfdk6s568krsj1x8qbk1kipy7m05xs6nwx19"))))
    (properties `((upstream-name . "lifecycle")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-glue" ,r-glue)
       ("r-rlang" ,r-rlang)))
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://github.com/r-lib/lifecycle")
    (synopsis "Manage the life cycle of your package functions")
    (description
     "Manage the life cycle of your exported functions with shared
conventions, documentation badges, and non-invasive deprecation warnings.  The
lifecycle package defines four development stages (experimental, maturing,
stable, and questioning) and three deprecation stages (soft-deprecated,
deprecated, and defunct).  It makes it easy to insert badges corresponding to
these stages in your documentation.  Usage of deprecated functions are
signalled with increasing levels of non-invasive verbosity.")
    (license license:gpl3)))

(define-public r-assertable
  (package
    (name "r-assertable")
    (version "0.2.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertable" version))
       (sha256
        (base32
         "1npks9rcrnchmd0silq6qrvqkmdkp9fwjkyyvvp1lqjclyxk6vkk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)))
    (home-page "https://cran.r-project.org/web/packages/assertable/")
    (synopsis "Verbose assertions for tabular data (data.frames and data.tables)")
    (description "This package provides simple, flexible assertions on
data.frame or data.table objects with verbose output for vetting.  While other
assertion packages apply towards more general use-cases, @code{assertable} is
tailored towards tabular data.  It includes functions to check variable names
and values, whether the dataset contains all combinations of a given set of
unique identifiers, and whether it is a certain length.  In addition,
@code{assertable} includes utility functions to check the existence of target
files and to efficiently import multiple tabular data files into one
data.table.")
    (license license:gpl3)))

(define-public r-quadprog
  (package
    (name "r-quadprog")
    (version "1.5-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "quadprog" version))
       (sha256
        (base32 "1ka9g8zak8sg4y2xbz93dfrldznlk9qpd4pq9z21cdcdn3b8s4i2"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/quadprog")
    (synopsis "Functions to solve quadratic programming problems")
    (description
     "This package contains routines and documentation for solving quadratic
programming problems.")
    (license license:gpl3+)))

(define-public r-desolve
  (package
    (name "r-desolve")
    (version "1.28")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "deSolve" version))
       (sha256
        (base32 "0jasvdzig0pzhzspmy20089az19r91xjfb9q6h8gj7c4mr6fymac"))))
    (properties `((upstream-name . "deSolve")))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://desolve.r-forge.r-project.org/")
    (synopsis "Solvers for initial value problems of differential equations")
    (description "This package provides functions that solve initial value
problems of a system of first-order @dfn{ordinary differential
equations} (ODE), of @dfn{partial differential equations} (PDE), of
@dfn{differential algebraic equations} (DAE), and of delay differential
equations.  The functions provide an interface to the FORTRAN functions
@code{lsoda}, @code{lsodar}, @code{lsode}, @code{lsodes} of the ODEPACK
collection, to the FORTRAN functions @code{dvode} and @code{daspk} and a
C-implementation of solvers of the Runge-Kutta family with fixed or variable
time steps.  The package contains routines designed for solving ODEs resulting
from 1-D, 2-D and 3-D partial differential equations that have been converted
to ODEs by numerical differencing.")
    (license license:gpl2+)))

(define-public r-pracma
  (package
    (name "r-pracma")
    (version "2.2.9")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "pracma" version))
              (sha256
               (base32 "07mzhzz73wsjjw1q05l024gcd13hwnzsxf873q9dyhw6x3shzshc"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/pracma/")
    (synopsis "Practical numerical math functions")
    (description "This package provides functions for numerical analysis and
linear algebra, numerical optimization, differential equations, plus some
special functions.  It uses Matlab function names where appropriate to simplify
porting.")
    (license license:gpl3+)))

(define-public r-subplex
  (package
    (name "r-subplex")
    (version "1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "subplex" version))
       (sha256
        (base32
         "1yfbfjvpbhgky7vihw3f4jl41pxpqb39z4nc045d5z7z48bdl18d"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/subplex")
    (synopsis "Unconstrained optimization using the subplex algorithm")
    (description
     "This package implements the Subplex optimization algorithm.
It solves unconstrained optimization problems using a simplex method on
subspaces.  The method is well suited for optimizing objective functions that
are noisy or are discontinuous at the solution.")
    (license license:gpl3+)))

(define-public r-txtplot
  (package
    (name "r-txtplot")
    (version "1.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "txtplot" version))
       (sha256
        (base32
         "1949ab1bzvysdb79g8x1gaknj0ih3d6g63pv9512h5m5l3a6c31h"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/txtplot/")
    (synopsis "Text-based plotting")
    (description "This package provides functions to produce rudimentary ASCII
graphics directly in the terminal window.  This package provides a basic
plotting function (and equivalents of curve, density, acf and barplot) as well
as a boxplot function.")
    (license license:lgpl3+)))

(define-public r-bio3d
  (package
    (name "r-bio3d")
    (version "2.4-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bio3d" version))
       (sha256
        (base32
         "07rw6c2d95gb5myxh31727j0jrchd0xisa3x89jjmf4zzs3vv7v7"))))
    (properties `((upstream-name . "bio3d")))
    (build-system r-build-system)
    (inputs `(("zlib" ,zlib)))
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "http://thegrantlab.org/bio3d/")
    (synopsis "Biological structure analysis")
    (description
     "This package provides utilities to process, organize and explore protein
structure, sequence and dynamics data.  Features include the ability to read
and write structure, sequence and dynamic trajectory data, perform sequence
and structure database searches, data summaries, atom selection, alignment,
superposition, rigid core identification, clustering, torsion analysis,
distance matrix analysis, structure and sequence conservation analysis, normal
mode analysis, principal component analysis of heterogeneous structure data,
and correlation network analysis from normal mode and molecular dynamics data.
In addition, various utility functions are provided to enable the statistical
and graphical power of the R environment to work with biological sequence and
structural data.")
    (license license:gpl2+)))

(define-public r-bios2cor
  (package
    (name "r-bios2cor")
    (version "2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Bios2cor" version))
       (sha256
        (base32
         "04wk1cjrrxhpv1kdhd67r1qvjv268xxi0z0r105wy912110z9m6x"))))
    (properties `((upstream-name . "Bios2cor")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bigmemory" ,r-bigmemory)
       ("r-bio3d" ,r-bio3d)
       ("r-circular" ,r-circular)
       ("r-igraph" ,r-igraph)))
    (home-page "https://cran.r-project.org/web/packages/Bios2cor/")
    (synopsis "From biological sequences and simulations to correlation analysis")
    (description
     "This package provides utilities for computation and analysis of
correlation/covariation in multiple sequence alignments and in side chain
motions during molecular dynamics simulations.  Features include the
computation of correlation/covariation scores using a variety of scoring
functions between either sequence positions in alignments or side chain
dihedral angles in molecular dynamics simulations and utilities to analyze the
correlation/covariation matrix through a variety of tools including network
representation and principal components analysis.  In addition, several
utility functions are based on the R graphical environment to provide friendly
tools for help in data interpretation.")
    (license license:gpl2+)))

;; This package includes minified JavaScript files.  When upgrading please
;; check that there are no new minified JavaScript files.
(define-public r-networkd3
  (package
    (name "r-networkd3")
    (version "0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "networkD3" version))
       (sha256
        (base32
         "02wxki67drppgfka1is1ykg1f2rxf0x0657c0crj7ipfy62jbf1k"))
       (snippet
        '(begin
           (delete-file "inst/htmlwidgets/lib/d3-4.5.0/d3.min.js")
           #t))))
    (properties `((upstream-name . "networkD3")))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst/htmlwidgets/lib/"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "d3.v4.js")
                         "d3-4.5.0/d3.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ;; NOTE: Make sure that this version of d3 is still valid when
       ;; upgrading the package.
       ("d3.v4.js"
        ,(origin
           (method url-fetch)
           (uri "https://d3js.org/d3.v4.js")
           (sha256
            (base32
             "0y7byf6kcinfz9ac59jxc4v6kppdazmnyqfav0dm4h550fzfqqlg"))))))
    (propagated-inputs
     `(("r-htmlwidgets" ,r-htmlwidgets)
       ("r-igraph" ,r-igraph)
       ("r-magrittr" ,r-magrittr)))
    (home-page "https://cran.r-project.org/package=networkD3")
    (synopsis "D3 JavaScript network graphs from R")
    (description
     "This package creates D3 JavaScript network, tree, dendrogram, and Sankey
graphs from R.")
    (license license:gpl3+)))

(define-public r-aasea
  (package
    (name "r-aasea")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "aaSEA" version))
       (sha256
        (base32
         "0him4r8qyp0xssgrmdxjs45yn4d28h5anv4jyxxbbs9phb0m6j3h"))))
    (properties `((upstream-name . "aaSEA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bios2cor" ,r-bios2cor)
       ("r-dt" ,r-dt)
       ("r-hmisc" ,r-hmisc)
       ("r-magrittr" ,r-magrittr)
       ("r-networkd3" ,r-networkd3)
       ("r-plotly" ,r-plotly)
       ("r-seqinr" ,r-seqinr)
       ("r-shiny" ,r-shiny)
       ("r-shinydashboard" ,r-shinydashboard)))
    (home-page "https://cran.r-project.org/web/packages/aaSEA/")
    (synopsis "Amino acid substitution effect analyzer")
    (description
     "Given a protein multiple sequence alignment, it is a daunting task to
assess the effects of substitutions along sequence length.  The aaSEA package
is intended to help researchers to rapidly analyze property changes caused by
single, multiple and correlated amino acid substitutions in proteins.")
    (license license:gpl3)))

(define-public r-abacus
  (package
    (name "r-abacus")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABACUS" version))
       (sha256
        (base32
         "0m1dnkwjr1522l9ddbzzx7ayxvli17sbmk6s28adpmzzjwh2kd1i"))))
    (properties `((upstream-name . "ABACUS")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-shiny" ,r-shiny)))
    (home-page "https://shiny.abdn.ac.uk/Stats/apps/")
    (synopsis "Apps-based activities for communicating and understanding statistics")
    (description
     "This package provides a set of Shiny apps for effective communication
and understanding in statistics.  The current version includes properties of
normal distribution, properties of sampling distribution, one-sample z and t
tests, two samples independent (unpaired) t test and analysis of variance.")
    (license license:gpl3)))

(define-public r-abc-rap
  (package
    (name "r-abc-rap")
    (version "0.9.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABC.RAP" version))
       (sha256
        (base32
         "1kdspln17v0krvahcd55vib4dv5azp60b3r1zf489x10qqbp1mxk"))))
    (properties `((upstream-name . "ABC.RAP")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ABC.RAP/")
    (synopsis "Array-based CpG region analysis pipeline")
    (description
     "This package aims to identify candidate genes that are differentially
methylated between cases and controls.  It applies Student's t-test and delta
beta analysis to identify candidate genes containing multiple CpG sites.")
    (license license:gpl3)))

(define-public r-abcadm
  (package
    (name "r-abcadm")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abcADM" version))
       (sha256
        (base32
         "0vcabnnnwc0psv9v3rda5aap9s8cq1pjh02zva3ki64hlavf2a10"))))
    (properties `((upstream-name . "abcADM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/abcADM/")
    (synopsis "Fit accumulated damage models and estimate reliability using ABC")
    (description
     "This package provides tools to estimate parameters of accumulated
damage (load duration) models based on failure time data under a Bayesian
framework, using @dfn{Approximate Bayesian Computation} (ABC), and to assess
long-term reliability under stochastic load profiles.")
    (license license:gpl3)))

(define-public r-rglpk
  (package
    (name "r-rglpk")
    (version "0.6-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rglpk" version))
       (sha256
        (base32
         "19mzpyimzq9zqnbi05j79b2di3nzaln8swggs9p8sqdr60qvr3d2"))))
    (properties `((upstream-name . "Rglpk")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-slam" ,r-slam)))
    (inputs
     `(("glpk" ,glpk)))
    (home-page "https://r-forge.r-project.org/projects/rglp/")
    (synopsis "R interface to the GNU Linear Programming Kit")
    (description
     "This package provides an R interface to the GNU Linear Programming Kit,
software for solving large-scale @dfn{linear programming} (LP), @dfn{mixed
integer linear programming} (MILP) and other related problems.")
    ;; Either license
    (license (list license:gpl2 license:gpl3))))

(define-public r-abcdefba
  (package
    (name "r-abcdefba")
    (version "0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abcdeFBA" version))
       (sha256
        (base32
         "1rxjripy8v6bxi25vdfjnbk24zkmf752qbl73cin6nvnqflwxkx4"))))
    (properties `((upstream-name . "abcdeFBA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-corrplot" ,r-corrplot)
       ("r-lattice" ,r-lattice)
       ("r-rgl" ,r-rgl)
       ("r-rglpk" ,r-rglpk)))
    (home-page "https://cran.r-project.org/web/packages/abcdeFBA/")
    (synopsis "A-Biologist-Can-Do-Everything of Flux Balance Analysis with this package")
    (description
     "This package provides functions for Constraint Based Simulation using
Flux Balance Analysis and informative analysis of the data generated during
simulation.")
    (license license:gpl2)))

(define-public r-abcrlda
  (package
    (name "r-abcrlda")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abcrlda" version))
       (sha256
        (base32
         "0zjdrbg3zx0znqnh0dvmifs9c12b8vjhbaf3nbwab9xh25nsmg75"))))
    (properties `((upstream-name . "abcrlda")))
    (build-system r-build-system)
    (home-page "https://ieeexplore.ieee.org/document/8720003/")
    (synopsis "Asymptotically bias-corrected regularized linear discriminant analysis")
    (description
     "This package offers methods to perform @dfn{asymptotically
bias-corrected regularized linear discriminant analysis} (ABC_RLDA) for
cost-sensitive binary classification.  The bias-correction is an estimate of
the bias term added to regularized discriminant analysis that minimizes the
overall risk.")
    (license license:gpl3)))

(define-public r-abemus
  (package
    (name "r-abemus")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abemus" version))
       (sha256
        (base32
         "1dhllb184byp1yl15rg2w02zgw3iajag7cxshirg47mnmm7n70bb"))))
    (properties `((upstream-name . "abemus")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)))
    (home-page "https://cran.r-project.org/web/packages/abemus/")
    (synopsis "Adaptive base error model in ultra-deep sequencing data")
    (description
     "This package provides an implementation of @dfn{Adaptive Base Error
Model in Ultra-deep Sequencing data} (ABEMUS), which combines
platform-specific genetic knowledge and empirical signal to readily detect and
quantify somatic @dfn{single nucleotide variants} (SNVs) in @dfn{circulating
cell free DNA} (cfDNA).")
    (license license:gpl3)))

;; This package includes minified JavaScript files.  When upgrading please
;; check that there are no new minified JavaScript files.
(define-public r-rintrojs
  (package
    (name "r-rintrojs")
    (version "0.2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rintrojs" version))
       (sha256
        (base32
         "0vyqb3pyrh12saddar71ac9csn2vkd2j8ln6ygpqys8ky1lc3427"))))
    (properties `((upstream-name . "rintrojs")))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst/javascript/introjs/"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "intro.js")
                         "intro.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("intro.js"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/usablica/intro.js/v2.9.3/intro.js")
           (sha256
            (base32
             "1qf8n1sfy9qkiqqnfgg0xbhmfgh0g3mqsjas8qhz230h3zzlzxj8"))))))
    (propagated-inputs
     `(("r-jsonlite" ,r-jsonlite)
       ("r-shiny" ,r-shiny)))
    (home-page "https://github.com/carlganz/rintrojs")
    (synopsis "Wrapper for the Intro.js library")
    (description
     "This package provides a wrapper for the @url{http://www.introjs.com,
Intro.js} library.  This package makes it easy to include step-by-step
introductions, and clickable hints in a Shiny application.  It supports both
static introductions in the UI, and programmatic introductions from the
server-side.")
    (license license:agpl3+)))

(define-public r-sysfonts
  (package
    (name "r-sysfonts")
    (version "0.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sysfonts" version))
       (sha256
        (base32
         "0wng902plryf2d8fc7k7m3jx11acz51kb2d91cqbyhq7xpk06z43"))))
    (properties `((upstream-name . "sysfonts")))
    (build-system r-build-system)
    (inputs
     `(("freetype" ,freetype)
       ("libpng" ,libpng)
       ("zlib" ,zlib)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/yixuan/sysfonts")
    (synopsis "Loading fonts into R")
    (description
     "This is a package to simplify loading of system fonts and Google Fonts
into R, in order to support other packages.")
    (license license:gpl2)))

(define-public r-showtextdb
  (package
    (name "r-showtextdb")
    (version "2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "showtextdb" version))
       (sha256
        (base32
         "1qwwj9x2jvadvwn60h75k99c9xi7yhqjsgaakahz5paxgj583bsh"))))
    (properties `((upstream-name . "showtextdb")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-sysfonts" ,r-sysfonts)))
    (home-page "https://cran.r-project.org/web/packages/showtextdb/")
    (synopsis "Font files for the 'showtext' package")
    (description
     "This package provides font files that can be used by the @code{showtext}
package.")
    (license license:asl2.0)))

(define-public r-showtext
  (package
    (name "r-showtext")
    (version "0.7-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "showtext" version))
       (sha256
        (base32
         "0a5gg72bfrc7wm0phj1aflj1wc08kfi81ac32na6ya9s2ivyimw5"))))
    (properties `((upstream-name . "showtext")))
    (build-system r-build-system)
    (inputs
     `(("freetype" ,freetype)
       ("libpng" ,libpng)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-showtextdb" ,r-showtextdb)
       ("r-sysfonts" ,r-sysfonts)))
    (native-inputs `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/yixuan/showtext")
    (synopsis "Using fonts more easily in R graphs")
    (description
     "This package aims to make it easy to use various types of
fonts (TrueType, OpenType, Type 1, web fonts, etc.) in R graphs, and supports
most output formats of R graphics including PNG, PDF and SVG.  Text glyphs
will be converted into polygons or raster images, hence after the plot has
been created, it no longer relies on the font files.  No external software
such as Ghostscript is needed to use this package.")
    (license license:asl2.0)))

(define-public r-emojifont
  (package
    (name "r-emojifont")
    (version "0.5.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "emojifont" version))
       (sha256
        (base32
         "1cdrrl3hvrs8rskyy6zgr7q2mmg8yb9k8sld1m64zsp7y009g19k"))))
    (properties `((upstream-name . "emojifont")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-proto" ,r-proto)
       ("r-showtext" ,r-showtext)
       ("r-sysfonts" ,r-sysfonts)))
    (home-page "https://guangchuangyu.github.io/emojifont")
    (synopsis "Emoji and Font Awesome in R graphics")
    (description
     "This package enables the use of emoji and the Font Awesome glyphs in
both base and ggplot2 graphics.")
    (license license:artistic2.0)))

(define-public r-abstractr
  (package
    (name "r-abstractr")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abstractr" version))
       (sha256
        (base32
         "1ymwp7syrynwd4i8aj2x5n8jdi9d96fjzl6jb09n0bnr5fgl7vig"))))
    (properties `((upstream-name . "abstractr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colourpicker" ,r-colourpicker)
       ("r-emojifont" ,r-emojifont)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-rintrojs" ,r-rintrojs)
       ("r-shiny" ,r-shiny)
       ("r-shinythemes" ,r-shinythemes)))
    (home-page "https://matt-kumar.shinyapps.io/portfolio")
    (synopsis "R-Shiny application for creating visual abstracts")
    (description
     "This package provides an R Shiny application to create visual abstracts
for original research.  A variety of user defined options and formatting are
included.")
    (license license:gpl3)))

(define-public r-abtest
  (package
    (name "r-abtest")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abtest" version))
       (sha256
        (base32
         "1ky3cf827kj24bhcpk00v5zl5jdkii1gca0x81ay1cjkzfispgws"))))
    (properties `((upstream-name . "abtest")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-plotrix" ,r-plotrix)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-rcpp" ,r-rcpp)
       ("r-sn" ,r-sn)
       ("r-truncnorm" ,r-truncnorm)
       ("r-vgam" ,r-vgam)))
    (home-page "https://cran.r-project.org/web/packages/abtest/")
    (synopsis "Bayesian A/B testing")
    (description
     "This package provides functions for Bayesian A/B testing including prior
elicitation options based on Kass and Vaidyanathan (1992)
@url{doi:10.1111/j.2517-6161.1992.tb01868.x}.")
    (license license:gpl2+)))

(define-public r-accept
  (package
    (name "r-accept")
    (version "0.7.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accept" version))
       (sha256
        (base32
         "0pn8q0jsi0nb2mm2kv6sjczflflshhy55y7nqqnk70yx9f6wm83y"))))
    (properties `((upstream-name . "accept")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-extrafont" ,r-extrafont)
       ("r-mass" ,r-mass)
       ("r-plotly" ,r-plotly)
       ("r-stringr" ,r-stringr)
       ("r-viridis" ,r-viridis)))
    (home-page "https://cran.r-project.org/web/packages/accept/")
    (synopsis "Acute COPD Exacerbation Prediction Tool (ACCEPT)")
    (description
     "This package allows clinicians to predict the rate and severity of
future acute exacerbation in @dfn{Chronic Obstructive Pulmonary
Disease} (COPD) patients, based on the clinical prediction model published in
Adibi et al. (2019) @url{doi:10.1101/651901}.")
    (license license:gpl3)))

(define-public r-smpracticals
  (package
    (name "r-smpracticals")
    (version "1.4-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SMPracticals" version))
       (sha256
        (base32
         "0zxq84f9i3b86xx6msb25b61gyj9k09iab2b7wg4d93yas9qzayf"))))
    (properties `((upstream-name . "SMPracticals")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ellipse" ,r-ellipse)
       ("r-mass" ,r-mass)
       ("r-nlme" ,r-nlme)
       ("r-survival" ,r-survival)))
    (home-page "http://statwww.epfl.ch/davison/SM/")
    (synopsis "Practicals for use with Davison (2003) Statistical Models")
    (description
     "This package contains the datasets and a few functions for use with the
practicals outlined in Appendix A of the book Statistical Models (Davison,
2003, Cambridge University Press).  The practicals themselves can be found at
@url{http://statwww.epfl.ch/davison/SM/}.")
    (license license:gpl2+)))

(define-public r-fgui
  (package
    (name "r-fgui")
    (version "1.0-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fgui" version))
       (sha256
        (base32
         "024fzd1c7iwqprn26hwjb9l2qlvvyzl449d7iixy0x69djwsrysv"))))
    (properties `((upstream-name . "fgui")))
    (build-system r-build-system)
    (home-page
     "https://sites.google.com/site/thomashoffmannproject/software/fgui")
    (synopsis "Create GUI for R functions")
    (description
     "Rapidly create a GUI for a function you created by automatically
creating widgets for arguments of the function.  This package automatically
parses help routines for context-sensitive help to these arguments.  The
interface is essentially a wrapper to some Tcl/Tk routines to both simplify
and facilitate GUI creation.  More advanced Tcl/Tk routines/GUI objects can be
incorporated into the interface for greater customization for the more
experienced.")
    ;; Any version of the GPL.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-tcltk2
  (package
    (name "r-tcltk2")
    (version "1.2-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tcltk2" version))
       (sha256
        (base32
         "1ibxld379600xx7kiqq3fck083s8psry12859980218rnzikl65d"))))
    (properties `((upstream-name . "tcltk2")))
    (build-system r-build-system)
    (inputs
     `(("tcl" ,tcl)
       ("tk" ,tk)))
    (home-page "https://www.sciviews.org/SciViews-R")
    (synopsis "Tcl/Tk additions")
    (description
     "This package provides a series of additional Tcl commands and Tk widgets
with style and various functions to supplement the tcltk package")
    (license license:lgpl3)))

(define-public r-accrual
  (package
    (name "r-accrual")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accrual" version))
       (sha256
        (base32
         "11clm9s5c5518nmp6hd6pjnp0s28y92b2i2x0xgj4j5g816p4j3z"))))
    (properties `((upstream-name . "accrual")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fgui" ,r-fgui)
       ("r-smpracticals" ,r-smpracticals)
       ("r-tcltk2" ,r-tcltk2)))
    (home-page "https://cran.r-project.org/web/packages/accrual/")
    (synopsis "Bayesian accrual prediction")
    (description
     "Subject recruitment for medical research is challenging.  Slow patient
accrual leads to delay in research.  Accrual monitoring during the process of
recruitment is critical.  Researchers need reliable tools to manage the
accrual rate.  This package provides an implementation of a Bayesian method
that integrates researcher's experience on previous trials and data from the
current study, providing reliable prediction on accrual rate for clinical
studies.  It provides functions for Bayesian accrual prediction which can be
easily used by statisticians and clinical researchers.")
    (license license:gpl2)))

(define-public r-accrued
  (package
    (name "r-accrued")
    (version "1.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accrued" version))
       (sha256
        (base32
         "05g1jb5914z18rcai1ahn7nihn27vr2rnadwv94gc1j7ivvikvs5"))))
    (properties `((upstream-name . "accrued")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/accrued/")
    (synopsis "Data quality visualization tools for partially accruing data")
    (description
     "This is a package for visualizing data quality of partially accruing
data.")
    (license license:gpl3)))

(define-public r-mda
  (package
    (name "r-mda")
    (version "0.4-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mda" version))
       (sha256
        (base32
         "19g6kn6g0shidrjfffklbmzc5w7mcimrxhagx4nmpslg59ibqdkh"))))
    (properties `((upstream-name . "mda")))
    (build-system r-build-system)
    (propagated-inputs `(("r-class" ,r-class)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/mda/")
    (synopsis "Mixture and flexible discriminant analysis")
    (description
     "This is a package for mixture and flexible discriminant analysis,
@dfn{multivariate adaptive regression splines} (MARS), BRUTO, and so on.")
    (license license:gpl2)))

(define-public r-elasticnet
  (package
    (name "r-elasticnet")
    (version "1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "elasticnet" version))
       (sha256
        (base32
         "0p9dplnsp28z4s2fl6afbwrgd0aj339fak8mmndicmrh7bb7rpmb"))))
    (properties `((upstream-name . "elasticnet")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lars" ,r-lars)))
    (home-page "http://users.stat.umn.edu/~zouxx019/")
    (synopsis "Elastic-Net for sparse estimation and sparse PCA")
    (description
     "This package provides functions for fitting the entire solution path of
the Elastic-Net and also provides functions for estimating sparse Principal
Components.  The Lasso solution paths can be computed by the same function.")
    (license license:gpl2+)))

(define-public r-sparselda
  (package
    (name "r-sparselda")
    (version "0.1-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sparseLDA" version))
       (sha256
        (base32
         "1k3sw9kc40yxnfss4vrsx34qxmv8ssddyhbfjhxrdldvblhbwchb"))))
    (properties `((upstream-name . "sparseLDA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-elasticnet" ,r-elasticnet)
       ("r-mass" ,r-mass)
       ("r-mda" ,r-mda)))
    (home-page "https://www.imm.dtu.dk/~lkhc/")
    (synopsis "Sparse discriminant analysis")
    (description
     "This package performs sparse linear discriminant analysis for Gaussians
and mixture of Gaussian models.")
    (license license:gpl2+)))

(define-public r-accsda
  (package
    (name "r-accsda")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accSDA" version))
       (sha256
        (base32
         "0sgxy5y8kkc1n35657kifwfjsba7y5m1vbr7rkk5lmbpkzahqm61"))))
    (properties `((upstream-name . "accSDA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-ggthemes" ,r-ggthemes)
       ("r-gridextra" ,r-gridextra)
       ("r-mass" ,r-mass)
       ("r-rarpack" ,r-rarpack)
       ("r-sparselda" ,r-sparselda)))
    (home-page "https://github.com/gumeo/accSDA/wiki")
    (synopsis "Accelerated sparse discriminant analysis")
    (description
     "This package provides an implementation of sparse linear discriminant
analysis, which is a supervised classification method for multiple classes.
Various novel optimization approaches to this problem are implemented
including @dfn{alternating direction method of multipliers} (ADMM),
@dfn{proximal gradient} (PG) and @dfn{accelerated proximal gradient} (APG).
Functions for performing cross validation are also supplied along with basic
prediction and plotting functions.  @dfn{Sparse zero variance
discriminant} (SZVD) analysis is also included in the package.")
    (license license:gpl2+)))

(define-public r-ace2fastq
  (package
    (name "r-ace2fastq")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ace2fastq" version))
       (sha256
        (base32
         "09kk3yyqnr2xp820g0p3aai9a21figigjr9lxkr3zjq2d8gzwfic"))))
    (properties `((upstream-name . "ace2fastq")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-stringr" ,r-stringr)))
    (home-page "https://github.com/c5sire/ace2fastq")
    (synopsis "ACE file to FASTQ converter")
    (description
     "The ACE file format is used in genomics to store contigs from sequencing
machines.  This tools converts it into FASTQ format.  Both formats contain the
sequence characters and their corresponding quality information.  Unlike the
FASTQ file, the ACE file stores the quality values numerically.  The
conversion algorithm uses the standard Sanger formula.  The package
facilitates insertion into pipelines, and content inspection.")
    (license license:gpl3)))

(define-public r-rngwell
  (package
    (name "r-rngwell")
    (version "0.10-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rngWELL" version))
       (sha256
        (base32
         "0pjjcs9pqj7mf0mhb2cwd0aanqpwnm65bm86hk6mi2vw8rgnj2vv"))))
    (properties `((upstream-name . "rngWELL")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rngWELL/")
    (synopsis "Toolbox for WELL random number generators")
    (description
     "This is a dedicated package to WELL pseudo random generators, which were
introduced in Panneton et al. (2006), ``Improved Long-Period Generators Based
on Linear Recurrences Modulo 2'', ACM Transactions on Mathematical Software.")
    (license license:bsd-3)))

(define-public r-randtoolbox
  (package
    (name "r-randtoolbox")
    (version "1.30.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "randtoolbox" version))
       (sha256
        (base32
         "0qg20ar6qns858jdzqhmfq7yji81czhr6cim257958gqpj66sn95"))))
    (properties `((upstream-name . "randtoolbox")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rngwell" ,r-rngwell)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/randtoolbox/")
    (synopsis "Toolbox for pseudo and quasi random number generation")
    (description
     "This package provides

@enumerate
@item pseudo random generators, such as general linear
congruential generators, multiple recursive generators and generalized
feedback shift register (SF-Mersenne Twister algorithm and WELL
generators)

@item quasi random generators, such as the Torus algorithm, the Sobol
sequence, the Halton sequence (including the Van der Corput sequence), and

@item some generator tests: the gap test, the serial test, the poker test.
@end enumerate

See e.g. Gentle (2003) @url{doi:10.1007/b97336}.")
    (license license:bsd-3)))

(define-public r-lhs
  (package
    (name "r-lhs")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lhs" version))
       (sha256
        (base32
         "0lzaqr7xi3ckln5nglv5xf5njm359slpz1jc6s02hpsqdw6armd4"))))
    (properties `((upstream-name . "lhs")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/bertcarnell/lhs")
    (synopsis "Latin Hypercube Samples")
    (description
     "This package provides a number of methods for creating and augmenting
Latin Hypercube Samples.")
    (license license:gpl3)))

(define-public r-acebayes
  (package
    (name "r-acebayes")
    (version "1.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acebayes" version))
       (sha256
        (base32
         "1imfwm1vpbb24vfmfn1nljhmaz8429mwjihw34892p387s8h7xz2"))))
    (properties `((upstream-name . "acebayes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-compare" ,r-compare)
       ("r-lhs" ,r-lhs)
       ("r-randtoolbox" ,r-randtoolbox)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "https://cran.r-project.org/web/packages/acebayes/")
    (synopsis "Optimal Bayesian experimental design using the ACE algorithm")
    (description
     "Finding an optimal Bayesian experimental design involves maximizing an
objective function given by the expectation of some appropriately chosen
utility function with respect to the joint distribution of unknown
quantities (including responses).  This objective function is usually not
available in closed form and the design space can be continuous and of high
dimensionality.  This package uses @dfn{Approximate Coordinate Exchange} (ACE)
to maximise an approximation to the expectation of the utility function.")
    (license license:gpl2)))

(define-public r-acet
  (package
    (name "r-acet")
    (version "1.8.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACEt" version))
       (sha256
        (base32
         "0626d6kg485xjya164wagrr5z223jvi93ywbwpdns7fkm03c0dlq"))))
    (properties `((upstream-name . "ACEt")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-mass" ,r-mass)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "https://cran.r-project.org/web/packages/ACEt/")
    (synopsis "Estimating dynamic heritability and twin model comparison")
    (description
     "This package supports twin models that are able to estimate the dynamic
behaviour of the variance components in the classical twin models with respect
to age using B-splines and P-splines.")
    (license license:gpl2+)))

(define-public r-acfmperiod
  (package
    (name "r-acfmperiod")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acfMPeriod" version))
       (sha256
        (base32
         "1yww8isfrbs2v9s94hx7p2imyszcgadwafdgpj438n2ik0q6p9d5"))))
    (properties `((upstream-name . "acfMPeriod")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/acfMPeriod/")
    (synopsis "Estimation of the ACF from the M-periodogram")
    (description
     "This package support non-robust and robust computations of the sample
autocovariance (ACOVF) and sample autocorrelation functions (ACF) of
univariate and multivariate processes.  The methodology consists in reversing
the diagonalization procedure involving the periodogram or the
cross-periodogram and the Fourier transform vectors, and, thus, obtaining the
ACOVF or the ACF as discussed in Fuller (1995)
@url{doi:10.1002/9780470316917}.  The robust version is obtained by fitting
robust M-regressors to obtain the M-periodogram or M-cross-periodogram as
discussed in Reisen et al. (2017) @url{doi:10.1016/j.jspi.2017.02.008}.")
    (license license:gpl2+)))

(define-public r-gamlss-data
  (package
    (name "r-gamlss-data")
    (version "5.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gamlss.data" version))
       (sha256
        (base32
         "1dgfspbmps6ipzcmw681wjdp320nm50dwsxafgrcwxndqgc7fdqd"))))
    (properties `((upstream-name . "gamlss.data")))
    (build-system r-build-system)
    (home-page "http://www.gamlss.org/")
    (synopsis "GAMLSS data")
    (description
     "This package provides data used as examples to demonstrate GAMLSS
models.")
    ;; Either version of the license
    (license (list license:gpl2 license:gpl3))))

(define-public r-gamlss
  (package
    (name "r-gamlss")
    (version "5.1-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gamlss" version))
       (sha256
        (base32
         "16b7ick1khvldbvfmmpw9cjs1vznnrisvifq7717fxzd8c9s5jdr"))))
    (properties `((upstream-name . "gamlss")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gamlss-data" ,r-gamlss-data)
       ("r-gamlss-dist" ,r-gamlss-dist)
       ("r-mass" ,r-mass)
       ("r-nlme" ,r-nlme)
       ("r-survival" ,r-survival)))
    (home-page "http://www.gamlss.org/")
    (synopsis "Generalized additive models for location scale and shape")
    (description
     "This package provides functions for fitting the generalized additive
models for location scale and shape introduced by Rigby and
Stasinopoulos (2005), @url{doi:10.1111/j.1467-9876.2005.00510.x}.  The models
use a distributional regression approach where all the parameters of the
conditional distribution of the response variable are modelled using
explanatory variables.")
    ;; Either version of the license
    (license (list license:gpl2 license:gpl3))))

(define-public r-acid
  (package
    (name "r-acid")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acid" version))
       (sha256
        (base32
         "030i0y8s283ivbsmjccpbv9v7mgbcg2jk9df7vgcbbns74swf9hd"))))
    (properties `((upstream-name . "acid")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gamlss" ,r-gamlss)
       ("r-gamlss-dist" ,r-gamlss-dist)
       ("r-hmisc" ,r-hmisc)))
    (home-page "https://cran.r-project.org/web/packages/acid/")
    (synopsis "Analysing conditional income distributions")
    (description
     "This package provides functions for the analysis of income distributions
for subgroups of the population as defined by a set of variables like age,
gender, region, etc.  This entails a Kolmogorov-Smirnov test for a mixture
distribution as well as functions for moments, inequality measures, entropy
measures and polarisation measures of income distributions.  This package thus
aides the analysis of income inequality by offering tools for the exploratory
analysis of income distributions at the disaggregated level.")
    (license license:gpl3)))

(define-public r-acm4r
  (package
    (name "r-acm4r")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acm4r" version))
       (sha256
        (base32
         "1wqzc35i1rshx0zlmas8y4qkkvy6h9r4i4apscjjv1xg2wjflzxa"))))
    (properties `((upstream-name . "acm4r")))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/acm4r/")
    (synopsis "Align-and-count method comparisons of RFLP data")
    (description
     "This is a package to compare sequence fragment lengths or molecular
weights from pairs of lanes.  The number of matching bands in the
@dfn{Restriction Fragment Length Polymorphism} (RFLP) data is calculated using
the align-and-count method.")
    ;; Any version of the GPL
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-filematrix
  (package
    (name "r-filematrix")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "filematrix" version))
       (sha256
        (base32
         "1v3aj1ng742msb0sfdnjsbqb508mqjf8jlq2v33vxldhradw5w0b"))))
    (properties `((upstream-name . "filematrix")))
    (build-system r-build-system)
    ;; These inputs are needed for vignettes
    (native-inputs
     `(("r-knitr" ,r-knitr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("pandoc-citeproc" ,ghc-pandoc-citeproc)))
    (home-page "https://github.com/andreyshabalin/filematrix")
    (synopsis "File-backed matrix class with convenient read and write access")
    (description
     "This package provides an interface for working with large matrices
stored in files, not in computer memory.  It supports multiple non-character
data types (double, integer, logical and raw) of various sizes (e.g.  8 and 4
byte real values).  Access to parts of the matrix is done by indexing, exactly
as with usual R matrices.  It supports very large matrices; the package has
been tested on multi-terabyte matrices.  It allows for more than 2^32 rows or
columns, ad allows for quick addition of extra columns to a filematrix.")
    (license license:lgpl3)))

(define-public r-acmeeqtl
  (package
    (name "r-acmeeqtl")
    (version "1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACMEeqtl" version))
       (sha256
        (base32
         "049xjv2ym35bbn43zwi68cq27fwdh404vp0r2ca5gxgmmx8kj1cz"))))
    (properties `((upstream-name . "ACMEeqtl")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-filematrix" ,r-filematrix)))
    (home-page "https://github.com/andreyshabalin/ACMEeqtl")
    (synopsis "Estimation of interpretable eQTL effect sizes")
    (description
     "This package provides a non-linear model, termed ACME, that reflects a
parsimonious biological model for allelic contributions of cis-acting eQTLs.
With non-linear least-squares algorithm the maximum likelihood parameters can
be estimated.  The ACME model provides interpretable effect size estimates and
p-values with well controlled Type-I error.")
    (license license:lgpl3)))

(define-public r-acmer
  (package
    (name "r-acmer")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acmeR" version))
       (sha256
        (base32
         "000b2hqlhj93958nddw0fqb15ahigs08najv2miivym046x04mf7"))))
    (properties `((upstream-name . "acmeR")))
    (build-system r-build-system)
    (propagated-inputs `(("r-foreign" ,r-foreign)))
    (home-page "https://cran.r-project.org/web/packages/acmeR/")
    (synopsis "ACME estimator of bird and bat mortality by wind turbines")
    (description
     "This package provides an implementation of the ACME estimator, described
in Wolpert (2015), ACME: A Partially Periodic Estimator of Avian & Chiropteran
Mortality at Wind Turbines.  Unlike most other models, this estimator supports
decreasing-hazard Weibull model for persistence; decreasing search proficiency
as carcasses age; variable bleed-through at successive searches; and interval
mortality estimates.  The package provides, based on search data, functions
for estimating the mortality inflation factor in Frequentist and Bayesian
settings.")
    (license license:expat)))

(define-public r-r-huge
  (package
    (name "r-r-huge")
    (version "0.9.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "R.huge" version))
       (sha256
        (base32
         "13p558qalv60pgr24nsm6mi92ryj65rsbqa6pgdwy0snjqx12bgi"))))
    (properties `((upstream-name . "R.huge")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-r-methodss3" ,r-r-methodss3)
       ("r-r-oo" ,r-r-oo)
       ("r-r-utils" ,r-r-utils)))
    (home-page "https://github.com/HenrikBengtsson/R.huge")
    (synopsis "Methods for accessing huge amounts of data")
    (description
     "This is a deprecated package for accessing huge amounts of data.
  Cross-platform alternatives are the following packages: bigmemory (CRAN),
ff (CRAN), or BufferedMatrix (Bioconductor).  The main usage of it was inside
the @code{aroma.affymetrix} package.")
    (license license:lgpl2.1+)))

(define-public r-r-filesets
  (package
    (name "r-r-filesets")
    (version "2.13.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "R.filesets" version))
       (sha256
        (base32
         "124rygq0bl9n4akxcm868nl30cyk3rz0iprb98zlpk62gci9f5fg"))))
    (properties `((upstream-name . "R.filesets")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-r-cache" ,r-r-cache)
       ("r-r-methodss3" ,r-r-methodss3)
       ("r-r-oo" ,r-r-oo)
       ("r-r-utils" ,r-r-utils)))
    (home-page "https://github.com/HenrikBengtsson/R.filesets")
    (synopsis "Easy handling of and access to files")
    (description
     "This package provides classes and methods to locate, setup, subset,
navigate and iterate file sets, i.e. sets of files located in one or more
directories on the file system.  The API is designed such that these classes
can be extended via inheritance to provide a richer API for special file
formats.  Moreover, a specific name format is defined such that filenames and
directories can be considered to have full names which consists of a name
followed by comma-separated tags.  This adds additional flexibility to
identify file sets and individual files.")
    (license license:lgpl2.1+)))

(define-public r-r-devices
  (package
    (name "r-r-devices")
    (version "2.16.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "R.devices" version))
       (sha256
        (base32
         "15zlnq3g27whq26fbcy5zfl5hiddm256h4rga4frblg6wqlbkvdd"))))
    (properties `((upstream-name . "R.devices")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-r-methodss3" ,r-r-methodss3)
       ("r-r-oo" ,r-r-oo)
       ("r-r-utils" ,r-r-utils)))
    (home-page "https://github.com/HenrikBengtsson/R.devices")
    (synopsis "Unified handling of graphics devices")
    (description
     "This package provides functions for creating plots and image files in a
unified way regardless of output format (EPS, PDF, PNG, SVG, TIFF, WMF, etc.).
Default device options as well as scales and aspect ratios are controlled in a
uniform way across all device types.  Switching output format requires minimal
changes in code.  This package is ideal for large-scale batch processing,
because it will never leave open graphics devices or incomplete image files
behind, even on errors or user interrupts.")
    (license license:lgpl2.1+)))

(define-public r-acnr
  (package
    (name "r-acnr")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acnr" version))
       (sha256
        (base32
         "087hq4i7jp67ba2finzsqjfnqbiprl33na6ryjv9zqzsdawj9cym"))))
    (properties `((upstream-name . "acnr")))
    (build-system r-build-system)
    (home-page "https://github.com/mpierrejean/acnr")
    (synopsis "Annotated copy-number regions")
    (description
     "This package provides SNP array data from different types of copy-number
regions.  These regions were identified manually by the authors of the package
and may be used to generate realistic data sets with known truth.")
    (license license:lgpl2.1+)))

(define-public r-acopula
  (package
    (name "r-acopula")
    (version "0.9.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acopula" version))
       (sha256
        (base32
         "0vvbbw8pfs9jwfz5c57lw48pr0qj661r0ys007q6zf9jmlrhx1ln"))))
    (properties `((upstream-name . "acopula")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/acopula/")
    (synopsis "Modelling dependence with multivariate Archimax copulas")
    (description
     "Archimax copulas are a mixture of Archimedean and EV copulas.  This
package provides definitions of several parametric families of generator and
dependence function, computes CDF and PDF, estimates parameters, tests for
goodness of fit, generates random sample and checks copula properties for
custom constructs.  In the 2-dimensional case explicit formulas for density
are used, contrary to higher dimensions when all derivatives are linearly
approximated.  Several non-archimax families (normal, FGM, Plackett) are
provided as well.")
    (license license:gpl2)))

(define-public r-tuner
  (package
    (name "r-tuner")
    (version "1.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tuneR" version))
       (sha256
        (base32
         "0av978m4h2iqazyfq6n2cgkh4wpllihh7s29lah2nb8ngc0w5hxx"))))
    (properties `((upstream-name . "tuneR")))
    (build-system r-build-system)
    (propagated-inputs `(("r-signal" ,r-signal)))
    (home-page "https://cran.r-project.org/web/packages/tuneR/")
    (synopsis "Analysis of music and speech")
    (description
     "This is a package for the analysis of music and speech.  Analyze music
and speech, extract features like MFCCs, handle wave files and their
representation in various ways, read MP3, read MIDI, perform steps of a
transcription, ...")
    ;; Either of these versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-seewave
  (package
    (name "r-seewave")
    (version "2.1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "seewave" version))
       (sha256
        (base32
         "1qg8f5gik9pw6f9mcxqmrc9x3003s8vdm6g01pjjpyc9qaqiz2vi"))))
    (properties `((upstream-name . "seewave")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-tuner" ,r-tuner)))
    (home-page "http://rug.mnhn.fr/seewave")
    (synopsis "Sound analysis and synthesis")
    (description
     "This package provides functions for analysing, manipulating, displaying,
editing and synthesizing time waves (particularly sound).  This package
processes time analysis (oscillograms and envelopes), spectral content,
resonance quality factor, entropy, cross correlation and autocorrelation,
zero-crossing, dominant frequency, analytic signal, frequency coherence, 2D
and 3D spectrograms and many other analyses.")
    (license license:gpl2+)))

(define-public r-acousticndlcoder
  (package
    (name "r-acousticndlcoder")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AcousticNDLCodeR" version))
       (sha256
        (base32
         "1fgzgwanpv2pzy74xdk3hamc44p8qch467wh163dxby8jr9ik0sb"))))
    (properties
     `((upstream-name . "AcousticNDLCodeR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-seewave" ,r-seewave)
       ("r-tuner" ,r-tuner)
       ("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/AcousticNDLCodeR/")
    (synopsis "Coding sound files for use with NDL")
    (description
     "Make acoustic cues to use with the R package @code{ndl}.
The package implements functions used in the PLoS ONE paper \"Words from
spontaneous conversational speech can be recognized with human-like accuracy
by an error-driven learning algorithm that discriminates between meanings
straight from smart acoustic features, bypassing the phoneme as recognition
unit.\" @url{doi:10.1371/journal.pone.0174623}")
    (license license:gpl2+)))

(define-public r-acp
  (package
    (name "r-acp")
    (version "2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acp" version))
       (sha256
        (base32
         "0lcwbjcyyr32m6qjmjqh25qjwrbyqj1n092xhgbhxzd8fslppnmn"))))
    (properties `((upstream-name . "acp")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quantmod" ,r-quantmod)
       ("r-tseries" ,r-tseries)))
    (home-page "https://cran.r-project.org/web/packages/acp/")
    (synopsis "Autoregressive conditional Poisson")
    (description
     "This package supports the analysis of count data exhibiting
autoregressive properties, using the @dfn{Autoregressive Conditional Poisson}
model (ACP(p,q)) proposed by Heinen (2003).")
    (license license:gpl2)))

(define-public r-ada
  (package
    (name "r-ada")
    (version "2.0-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ada" version))
       (sha256
        (base32
         "1h3a07czp0w3hrhjcg1fz721y8vsfclzqi3rq8qfzgpfb4h1f06r"))))
    (properties `((upstream-name . "ada")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rpart" ,r-rpart)))
    (home-page "https://cran.r-project.org/web/packages/ada/")
    (synopsis "Stochastic boosting")
    (description
     "This package provides a straightforward, well-documented, and broad
boosting routine for classification, ideally suited for small to
moderate-sized data sets.  It performs discrete, real, and gentle boost under
both exponential and logistic loss on a given data set.")
    ;; Any version of the GPL.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-genalg
  (package
    (name "r-genalg")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "genalg" version))
       (sha256
        (base32
         "1wzfamq8k5yhwbdx0wy1w5bks93brj0p890xxc4yqrja4w38ja3s"))))
    (properties `((upstream-name . "genalg")))
    (build-system r-build-system)
    (home-page "https://github.com/egonw/genalg")
    (synopsis "R based genetic algorithm")
    (description
     "This package provides an R based genetic algorithm for binary and
floating point chromosomes.")
    (license license:gpl2)))

(define-public r-kernelfactory
  (package
    (name "r-kernelfactory")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kernelFactory" version))
       (sha256
        (base32
         "001kw9k3ivd4drd4mwqapkkk3f4jgljiaprhg2630hmll064s89j"))))
    (properties `((upstream-name . "kernelFactory")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-auc" ,r-auc)
       ("r-genalg" ,r-genalg)
       ("r-kernlab" ,r-kernlab)
       ("r-randomforest" ,r-randomforest)))
    (home-page "https://cran.r-project.org/web/packages/kernelFactory/")
    (synopsis "Ensemble of kernel machines")
    (description
     "Kernel factory is an ensemble method where each base classifier (random
forest) is fit on the kernel matrix of a subset of the training data.")
    (license license:gpl2+)))

(define-public r-dummies
  (package
    (name "r-dummies")
    (version "1.5.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dummies" version))
       (sha256
        (base32
         "01f84crqx17xd6xy55qxlvsj3knm8lhw7jl26p2rh2w3y0nvqlbm"))))
    (properties `((upstream-name . "dummies")))
    (build-system r-build-system)
    (home-page "https://decisionpatterns.com")
    (synopsis "Create dummy/indicator variables flexibly and efficiently")
    (description
     "This package lets you expand factors, characters and other eligible
classes into dummy/indicator variables.")
    (license license:gpl2+)))

(define-public r-acrm
  (package
    (name "r-acrm")
    (version "0.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "aCRM" version))
       (sha256
        (base32
         "0kzp568hd9c9a9qgniia5s5gv0q5f89xfvvwpzb197gqhs3x092v"))))
    (properties `((upstream-name . "aCRM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ada" ,r-ada)
       ("r-dummies" ,r-dummies)
       ("r-kernelfactory" ,r-kernelfactory)
       ("r-randomforest" ,r-randomforest)))
    (home-page "https://cran.r-project.org/web/packages/aCRM/")
    (synopsis "Convenience functions for analytical customer relationship management")
    (description
     "This package provides convenience functions for data preparation and
modeling often used in @dfn{analytical customer relationship
management} (aCRM).")
    (license license:gpl2+)))

(define-public r-treeclust
  (package
    (name "r-treeclust")
    (version "1.1-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "treeClust" version))
       (sha256
        (base32
         "1s7kh6q0bkixsygrip95zf1bi10ihddsa5lq9dfxd68yh8rsby6z"))))
    (properties `((upstream-name . "treeClust")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cluster" ,r-cluster)
       ("r-rpart" ,r-rpart)))
    (home-page "https://cran.r-project.org/web/packages/treeClust/")
    (synopsis "Cluster distances through trees")
    (description
     "This package provides tools to create a measure of inter-point
dissimilarity useful for clustering mixed data, and, optionally, perform the
clustering.")
    (license license:gpl2+)))

(define-public r-acrosstic
  (package
    (name "r-acrosstic")
    (version "1.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AcrossTic" version))
       (sha256
        (base32
         "03180h79jhjd66ibrnsfp3yyp2jlfysp7cymw46phzj2palghsc0"))))
    (properties `((upstream-name . "AcrossTic")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lpsolve" ,r-lpsolve)
       ("r-treeclust" ,r-treeclust)))
    (home-page "https://cran.r-project.org/web/packages/AcrossTic/")
    (synopsis "Cost-minimal regular spanning subgraph with TreeClust")
    (description
     "This is a package for constructing minimum-cost regular spanning
subgraph as part of a non-parametric two-sample test for equality of
distribution.")
    (license license:gpl2+)))

(define-public r-acrt
  (package
    (name "r-acrt")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acrt" version))
       (sha256
        (base32
         "0y9ndcq8ffpfrv7w9rikm4zn68jpsj6baqisq9kp2433xrwzdb6s"))))
    (properties `((upstream-name . "acrt")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-sandwich" ,r-sandwich)))
    (home-page "https://cran.r-project.org/web/packages/acrt/")
    (synopsis "Autocorrelation robust testing")
    (description
     "This package provides functions for testing affine hypotheses on the
regression coefficient vector in regression models with autocorrelated
errors.")
    (license license:gpl2)))

(define-public r-acs
  (package
    (name "r-acs")
    (version "2.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acs" version))
       (sha256
        (base32
         "0ajw9rf8l8akcvgqvbxjvryc6wjx74521xyxswz2b0bky3m6kah5"))))
    (properties `((upstream-name . "acs")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-httr" ,r-httr)
       ("r-plyr" ,r-plyr)
       ("r-rcpp" ,r-rcpp)
       ("r-stringr" ,r-stringr)
       ("r-xml" ,r-xml)))
    (home-page "https://dusp.mit.edu/faculty/ezra-haber-glenn")
    (synopsis "Work with data from the US Census")
    (description
     "This package provides a general toolkit for downloading, managing,
analyzing, and presenting data from the
@url{https://www.census.gov/data/developers/data-sets.html, U.S.  Census},
including SF1 (Decennial short-form), SF3 (Decennial long-form), and the
American Community Survey (ACS).  Confidence intervals provided with ACS data
are converted to standard errors to be bundled with estimates in complex
@code{acs} objects.  The package provides new methods to conduct standard
operations on @code{acs} objects and present/plot data in statistically
appropriate ways.")
    (license license:gpl3)))

(define-public r-acss-data
  (package
    (name "r-acss-data")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acss.data" version))
       (sha256
        (base32
         "09kl4179ipr8bq19g89xcdi1xxs397zcx5cvgp6viy8gn687ilgv"))))
    (properties `((upstream-name . "acss.data")))
    (build-system r-build-system)
    (home-page "http://complexitycalculator.com/methodology.html")
    (synopsis "Data for algorithmic complexity of short strings")
    (description
     "This is a data only package providing the algorithmic complexity of
short strings, computed using the coding theorem method.  For a given set of
symbols in a string, all possible or a large number of random samples of
Turing machines with a given number of states (e.g., 5) and number of symbols
corresponding to the number of symbols in the strings were simulated until
they reached a halting state or failed to end.  This package contains data on
4.5 million strings from length 1 to 12 simulated on Turing machines with 2,
4, 5, 6, and 9 symbols.  The complexity of the string corresponds to the
distribution of the halting states.")
    (license license:gpl2+)))

(define-public r-acss
  (package
    (name "r-acss")
    (version "0.2-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acss" version))
       (sha256
        (base32
         "0cqa60544f58l5qd7h6xmsir40b9hqnq6pqgd5hfx2j2l5n7qhmk"))))
    (properties `((upstream-name . "acss")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-acss-data" ,r-acss-data)
       ("r-zoo" ,r-zoo)))
    (home-page "http://complexitycalculator.com/methodology.html")
    (synopsis "Algorithmic complexity for short strings")
    (description
     "The main purpose of this package is to provide the algorithmic
complexity for short strings, an approximation of the Kolmogorov Complexity of
a short string using the coding theorem method.  While the database containing
the complexity is provided in the data only package @code{acss.data}, this
package provides functions accessing the data such as @code{prob_random}
returning the posterior probability that a given string was produced by a
random process.  In addition, two traditional (but problematic) measures of
complexity are also provided: entropy and change complexity.")
    (license license:gpl2+)))

(define-public r-acswr
  (package
    (name "r-acswr")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACSWR" version))
       (sha256
        (base32
         "195vjrkang5cl7gwsna0aq4p0h4jym9xg9yh94bnf8vq6wf8j83n"))))
    (properties `((upstream-name . "ACSWR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ACSWR/")
    (synopsis "Companion package for the book \"A Course in Statistics with R\"")
    (description
     "This is a companion package for the book \"A Course in Statistics with
R\" (ISBN 978-1-119-15272-9.)")
    (license license:gpl2)))

(define-public r-alabama
  (package
    (name "r-alabama")
    (version "2015.3-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "alabama" version))
       (sha256
        (base32
         "0mlgk929gdismikwx4k2ndqq57nnqj7mlgvd3479b214hksgq036"))))
    (properties `((upstream-name . "alabama")))
    (build-system r-build-system)
    (propagated-inputs `(("r-numderiv" ,r-numderiv)))
    (home-page "https://cran.r-project.org/web/packages/alabama/")
    (synopsis "Constrained nonlinear optimization")
    (description
     "Alabama stands for Augmented Lagrangian Adaptive Barrier Minimization
Algorithm; it is used for optimizing smooth nonlinear objective functions with
constraints.  Linear or nonlinear equality and inequality constraints are
allowed.")
    (license license:gpl2+)))

(define-public r-gdina
  (package
    (name "r-gdina")
    (version "2.7.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GDINA" version))
       (sha256
        (base32
         "13pmj069r04h38hg61ibyn1ab15zdy9m0qv60vi25ahgsmg6ccvx"))))
    (properties `((upstream-name . "GDINA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-alabama" ,r-alabama)
       ("r-ggplot2" ,r-ggplot2)
       ("r-mass" ,r-mass)
       ("r-nloptr" ,r-nloptr)
       ("r-numderiv" ,r-numderiv)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rsolnp" ,r-rsolnp)
       ("r-shiny" ,r-shiny)
       ("r-shinydashboard" ,r-shinydashboard)))
    (home-page "https://github.com/Wenchao-Ma/GDINA")
    (synopsis "Generalized DINA model framework")
    (description
     "This package provides a set of psychometric tools for cognitive
diagnosis modeling based on the generalized deterministic inputs, noisy and
gate (G-DINA) model by de la Torre (2011) @url{doi:10.1007/s11336-011-9207-7}
and its extensions, including the sequential G-DINA model by Ma and de la
Torre (2016) @url{doi:10.1111/bmsp.12070} for polytomous responses, and the
polytomous G-DINA model by Chen and de la Torre
@url{doi:10.1177/0146621613479818} for polytomous attributes.  Joint attribute
distribution can be independent, saturated, higher-order, loglinear smoothed
or structured.  Q-matrix validation, item and model fit statistics, model
comparison at test and item level and differential item functioning can also
be conducted.  A graphical user interface is also provided.")
    (license license:gpl3)))

(define-public r-actcd
  (package
    (name "r-actcd")
    (version "1.2-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACTCD" version))
       (sha256
        (base32
         "0mzjxxr2zfdidw8ibh6w8mvpkw3q3nvngqi05g9ind26ckvk053p"))))
    (properties `((upstream-name . "ACTCD")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gdina" ,r-gdina)
       ("r-r-methodss3" ,r-r-methodss3)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/ACTCD/")
    (synopsis "Asymptotic classification theory for cognitive diagnosis")
    (description
     "This is a package supporting cluster analysis for cognitive diagnosis
based on the Asymptotic Classification Theory (Chiu, Douglas & Li, 2009;
@url{doi:10.1007/s11336-009-9125-0}).  Given the sample statistic of
sum-scores, cluster analysis techniques can be used to classify examinees into
latent classes based on their attribute patterns.  In addition to the
algorithms used to classify data, three labeling approaches are proposed to
label clusters so that examinees' attribute profiles can be obtained.")
    (license license:gpl2+)))

(define-public r-ineq
  (package
    (name "r-ineq")
    (version "0.2-13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ineq" version))
       (sha256
        (base32
         "09fsxyrh0j7mwmb5hkhmrzgcy7kf85jxkh7zlwpgqgcsyl1n91z0"))))
    (properties `((upstream-name . "ineq")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ineq/")
    (synopsis "Measuring inequality, concentration, and poverty")
    (description
     "This package provides tools for measuring inequality, concentration, and
poverty measures.  It provides both empirical and theoretical Lorenz curves.")
    ;; Either of these two versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-actfrag
  (package
    (name "r-actfrag")
    (version "0.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ActFrag" version))
       (sha256
        (base32
         "08r3gwjz4fkyy85dxqix0ffm5xyq45032qv3snnzxnlqxslxbqn1"))))
    (properties `((upstream-name . "ActFrag")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-accelerometry" ,r-accelerometry)
       ("r-dplyr" ,r-dplyr)
       ("r-ineq" ,r-ineq)
       ("r-survival" ,r-survival)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/junruidi/ActFrag")
    (synopsis "Activity fragmentation metrics extraction")
    (description
     "This package provides functions to extract commonly used fragmentation
metrics to quantify time accumulation strategies based on minute level
actigraphy-measured activity counts data.")
    (license license:gpl3)))

(define-public r-fda
  (package
    (name "r-fda")
    (version "2.4.8.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fda" version))
       (sha256
        (base32
         "0g50kj1dx7zarjv0lgwyzd2c7bv6di7nkndmywday5vjywgl8m7a"))))
    (properties `((upstream-name . "fda")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)))
    (home-page "https://www.functionaldata.org")
    (synopsis "Functional data analysis")
    (description
     "These functions were developed to support functional data analysis as
described in Ramsay, J. O. and Silverman, B. W. (2005) Functional Data
Analysis.  The package includes data sets and script files working many
examples.")
    (license license:gpl2+)))

(define-public r-actigraphy
  (package
    (name "r-actigraphy")
    (version "1.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Actigraphy" version))
       (sha256
        (base32
         "0bpmvszzv5fm72nar3wgnmfl5am7znqfajmlbv38ihkbi7jbwk20"))))
    (properties `((upstream-name . "Actigraphy")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fda" ,r-fda)))
    (home-page "https://cran.r-project.org/web/packages/Actigraphy/")
    (synopsis "Actigraphy data analysis")
    (description
     "This package provides tools for functional linear modeling and analysis
of actigraphy data.")
    (license license:asl2.0)))

(define-public r-activedriver
  (package
    (name "r-activedriver")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ActiveDriver" version))
       (sha256
        (base32
         "10c7ga48fwvpd5mc4dqiyw4kc2l0iz5qn4hg7xk15r1qmm5rsipa"))))
    (properties `((upstream-name . "ActiveDriver")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ActiveDriver/")
    (synopsis "Tools for finding cancer driver proteins")
    (description
     "This package provides a mutation analysis tool that discovers cancer
driver genes with frequent mutations in protein signalling sites such as
post-translational modifications (phosphorylation, ubiquitination, etc).  The
Poisson generalized linear regression model identifies genes where cancer
mutations in signalling sites are more frequent than expected from the
sequence of the entire gene.  Integration of mutations with signalling
information helps find new driver genes and propose candidate mechanisms to
known drivers.")
    (license license:gpl2+)))

(define-public r-activitycounts
  (package
    (name "r-activitycounts")
    (version "0.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "activityCounts" version))
       (sha256
        (base32
         "0zgxr2sk3a8kmygfxx1p5hnrfwdkxx7php6jlrhm8wv6052ck8jz"))))
    (properties
     `((upstream-name . "activityCounts")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-seewave" ,r-seewave)
       ("r-signal" ,r-signal)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/walkabillylab/activityCounts")
    (synopsis "Generate ActiLife counts")
    (description
     "ActiLife generates activity counts from data collected by Actigraph
accelerometers.  Actigraph is one of the most common research-grade
accelerometers.  There is considerable research validating and developing
algorithms for human activity using ActiLife counts.  Unfortunately, ActiLife
counts are proprietary and difficult to implement if researchers use different
accelerometer brands.  The code creates ActiLife counts from raw acceleration
data for different accelerometer brands.")
    (license license:gpl3)))

(define-public r-activityindex
  (package
    (name "r-activityindex")
    (version "0.3.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ActivityIndex" version))
       (sha256
        (base32
         "14k6d78s15j7kb7jhixf4msrdjdl28d0r264cbvy41p8dkq7ysvk"))))
    (properties `((upstream-name . "ActivityIndex")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-matrixstats" ,r-matrixstats)
       ("r-r-utils" ,r-r-utils)))
    (home-page "https://cran.r-project.org/web/packages/ActivityIndex/")
    (synopsis "Activity Index calculation using raw accelerometry data")
    (description
     "This is a package to read raw accelerometry from GT3X+ accelerometry
data and plain table data to calculate the Activity Index from Bai et
al. (2016) @url{doi:10.1371/journal.pone.0160644}.")
    (license license:gpl3)))

(define-public r-activpal
  (package
    (name "r-activpal")
    (version "0.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "activPAL" version))
       (sha256
        (base32
         "1h6hp5z89ji73gdzxy1dgbfwjysiy5lvcqh90xagpb7sa7ahs3na"))))
    (properties `((upstream-name . "activPAL")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-devtools" ,r-devtools)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://cran.r-project.org/web/packages/activPAL")
    (synopsis "Processing and chart generation from activPAL events files")
    (description
     "This package contains functions to generate pre-defined summary
statistics from activPAL events files.  The package also contains functions to
produce informative graphics that visualize physical activity behaviour and
trends.  This includes generating graphs that align physical activity
behaviour with additional time based observations described by other data
sets, such as sleep diaries and continuous glucose monitoring data.")
    (license license:gpl3)))

(define-public r-activpalprocessing
  (package
    (name "r-activpalprocessing")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "activpalProcessing" version))
       (sha256
        (base32
         "1y0bjx2qx53iy930y9iww4q1yzjj8y16cwgixk1mq3w4g1f116d1"))))
    (properties
     `((upstream-name . "activpalProcessing")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-chron" ,r-chron)))
    (home-page "https://cran.r-project.org/web/packages/activpalProcessing/")
    (synopsis "Process activPAL events files")
    (description
     "This package performs estimation of physical activity and sedentary
behavior variables from activPAL events files.")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

(define-public r-actogrammr
  (package
    (name "r-actogrammr")
    (version "0.2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "actogrammr" version))
       (sha256
        (base32
         "1jzvarmd41yqlrkagzlc8m19n5mn0w0b36fy50lyvgrfsafjfbqa"))))
    (properties `((upstream-name . "actogrammr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lubridate" ,r-lubridate)
       ("r-readr" ,r-readr)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://cran.r-project.org/web/packages/actogrammr/")
    (synopsis "Read in activity data and plot actograms")
    (description
     "Read in activity measurements from standard file formats used by
circadian rhythm researchers, currently only ClockLab format, and process and
plot the data.  The central type of plot is the actogram, as first described
in \"Activity and distribution of certain wild mice in relation to biotic
communities\" by MS Johnson (1926) @url{doi:10.2307/1373575}.")
    (license license:gpl3)))

(define-public r-expint
  (package
    (name "r-expint")
    (version "0.1-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "expint" version))
       (sha256
        (base32
         "0iai25cglcdnf44d2d1fz1xpw4q600my4zq4493fk4cs5673mlf7"))))
    (properties `((upstream-name . "expint")))
    (build-system r-build-system)
    (home-page "https://gitlab.com/vigou3/expint")
    (synopsis "Exponential integral and incomplete Gamma function")
    (description
     "This package provides the exponential integrals @code{E_1(x)},
@code{E_2(x)}, @code{E_n(x)} and @code{Ei(x)}, and the incomplete gamma
function @code{G(a, x)} defined for negative values of its first argument.
The package also gives easy access to the underlying C routines through an
API; see the package vignette for details.")
    (license license:gpl2+)))

(define-public r-actuar
  (package
    (name "r-actuar")
    (version "2.3-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "actuar" version))
       (sha256
        (base32
         "0aw3hlan5y22mdqk1wvnw9ksqhwp4yy5hi0dpv21p7s0hyxhphih"))))
    (properties `((upstream-name . "actuar")))
    (build-system r-build-system)
    (propagated-inputs `(("r-expint" ,r-expint)))
    (home-page "https://gitlab.com/vigou3/actuar")
    (synopsis "Actuarial functions and heavy tailed distributions")
    (description
     "This package provides functions and data sets for actuarial science:
modeling of loss distributions; risk theory and ruin theory; simulation of
compound models, discrete mixtures and compound hierarchical models;
credibility theory.  It boasts support for many additional probability
distributions to model insurance loss amounts and loss frequency: 19
continuous heavy tailed distributions; the Poisson-inverse Gaussian discrete
distribution; zero-truncated and zero-modified extensions of the standard
discrete distributions.  It also supports phase-type distributions commonly
used to compute ruin probabilities.")
    (license license:gpl2+)))

(define-public r-bmp
  (package
    (name "r-bmp")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bmp" version))
       (sha256
        (base32
         "0jd67r11bn98hjwgyr6gas423787xy7ji2hq7ay80blkkcj91xxx"))))
    (properties `((upstream-name . "bmp")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/bmp/")
    (synopsis "Read Bitmap (BMP) images")
    (description
     "This package provides pure R tools to read BMP format images.  It is
currently limited to 8 bit greyscale images and 24, 32 bit (A)RGB images.")
    (license license:gpl2+)))

(define-public r-readbitmap
  (package
    (name "r-readbitmap")
    (version "0.1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "readbitmap" version))
       (sha256
        (base32
         "14825906l326w59g6apy00j55jg3h5kx2r6s031f4gdkbrc7szbk"))))
    (properties `((upstream-name . "readbitmap")))
    (build-system r-build-system)
    (inputs
     `(("libjpeg" ,libjpeg)
       ("libpng" ,libpng)))
    (propagated-inputs
     `(("r-bmp" ,r-bmp)
       ("r-jpeg" ,r-jpeg)
       ("r-png" ,r-png)
       ("r-tiff" ,r-tiff)))
    (home-page "https://github.com/jefferis/readbitmap")
    (synopsis "Unified interface to read bitmap images (BMP, JPEG, PNG, TIFF)")
    (description
     "This package provides tools to identify and read BMP, JPEG, PNG, and
TIFF format bitmap images.  Identification defaults to the use of the magic
number embedded in the file rather than the file extension.")
    (license license:gpl2+)))

(define-public r-imager
  (package
    (name "r-imager")
    (version "0.42.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "imager" version))
       (sha256
        (base32
         "1d7a49lcna77wyfjf5q1b89jck3p3vnysnkgz4drb0qkpy6hz76b"))))
    (properties `((upstream-name . "imager")))
    (build-system r-build-system)
    (inputs
     `(("fftw" ,fftw)
       ("libtiff" ,libtiff)
       ("libx11" ,libx11)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-downloader" ,r-downloader)
       ("r-igraph" ,r-igraph)
       ("r-jpeg" ,r-jpeg)
       ("r-magrittr" ,r-magrittr)
       ("r-png" ,r-png)
       ("r-purrr" ,r-purrr)
       ("r-rcpp" ,r-rcpp)
       ("r-readbitmap" ,r-readbitmap)
       ("r-stringr" ,r-stringr)))
    (native-inputs `(("pkg-config" ,pkg-config)))
    (home-page "https://dahtah.github.io/imager/")
    (synopsis "Image processing library")
    (description
     "This is a package for fast image processing for images in up to 4
dimensions (two spatial dimensions, one time/depth dimension, one color
dimension).  It provides most traditional image processing tools (filtering,
morphology, transformations, etc.) as well as various functions for easily
analyzing image data using R.  The package wraps @url{http://cimg.eu, CImg}, a
simple, modern C++ library for image processing.")
    (license license:lgpl3)))

(define-public r-acuityview
  (package
    (name "r-acuityview")
    (version "0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AcuityView" version))
       (sha256
        (base32
         "0f0iclmnwdc8ixiiai4svk4x1g3pjy7dhm3cm58fv6ckx12d3d2l"))))
    (properties `((upstream-name . "AcuityView")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fftwtools" ,r-fftwtools)
       ("r-imager" ,r-imager)
       ("r-plotrix" ,r-plotrix)))
    (home-page "https://cran.r-project.org/web/packages/AcuityView/")
    (synopsis "Display scenes as seen by an animal with less acute vision")
    (description
     "This package provides a simple method for representing a visual scene as
it may be seen by an animal with less acute vision.")
    (license license:gpl2+)))

(define-public r-caret
  (package
    (name "r-caret")
    (version "6.0-86")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "caret" version))
       (sha256
        (base32
         "0dyflixdw98lvk2x3w136sw24ij0fwx5c7l709dmqr5z7xy1qjns"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-foreach" ,r-foreach)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lattice" ,r-lattice)
       ("r-modelmetrics" ,r-modelmetrics)
       ("r-nlme" ,r-nlme)
       ("r-plyr" ,r-plyr)
       ("r-proc" ,r-proc)
       ("r-recipes" ,r-recipes)
       ("r-reshape2" ,r-reshape2)
       ("r-withr" ,r-withr)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/topepo/caret")
    (synopsis "Classification and regression training")
    (description
     "This package provides miscellaneous functions for training and plotting
classification and regression models.")
    (license license:gpl2+)))

(define-public r-adabag
  (package
    (name "r-adabag")
    (version "4.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adabag" version))
       (sha256
        (base32
         "109wrl1pwvmyv2l909hrvk7dg4aa9pv449mvdycp50zwrsw9w0a7"))))
    (properties `((upstream-name . "adabag")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-caret" ,r-caret)
       ("r-doparallel" ,r-doparallel)
       ("r-foreach" ,r-foreach)
       ("r-rpart" ,r-rpart)))
    (home-page "https://cran.r-project.org/web/packages/adabag/")
    (synopsis "Multiclass AdaBoost.M1, SAMME and Bagging")
    (description
     "This package implements Freund and Schapire's Adaboost.M1 algorithm and
Breiman's Bagging algorithm using classification trees as individual
classifiers.  Once these classifiers have been trained, they can be used to
predict on new data.  Also, cross validation estimation of the error can be
done.")
    (license license:gpl2+)))

(define-public r-adagio
  (package
    (name "r-adagio")
    (version "0.7.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adagio" version))
       (sha256
        (base32
         "1h9l0ddrxq8y35iy9hdkxdvdwsqpnpkzzbkbwwhm4380lq1m7a3k"))))
    (properties `((upstream-name . "adagio")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/adagio/")
    (synopsis "Discrete and global optimization routines")
    (description
     "This package provides methods and algorithms for discrete optimization,
e.g. knapsack and subset sum procedures, derivative-free Nelder-Mead and
Hooke-Jeeves minimization, and some (evolutionary) global optimization
functions.")
    (license license:gpl3+)))

(define-public r-univoutl
  (package
    (name "r-univoutl")
    (version "0.1-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "univOutl" version))
       (sha256
        (base32
         "193wrpkvgmlrx43nag8w3ivrlqm37nm6g86wcvd3bgw3hchs70gi"))))
    (properties `((upstream-name . "univOutl")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-hmisc" ,r-hmisc)
       ("r-robustbase" ,r-robustbase)))
    (home-page "https://github.com/marcellodo/univOutl")
    (synopsis "Detection of univariate outliers")
    (description
     "This package provides well-known outlier detection techniques in the
univariate case.  Methods to deal with skewed distribution are included too.
The Hidiroglou-Berthelot (1986) method to search for outliers in ratios of
historical data is implemented as well.  When available, survey weights can be
used in outliers detection.")
    (license license:gpl2+)))

(define-public r-tolerance
  (package
    (name "r-tolerance")
    (version "2.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tolerance" version))
       (sha256
        (base32
         "001snzr2ipag3zprynydlbi9prkjzrllc054qh7m0qwkb3r19jjd"))))
    (properties `((upstream-name . "tolerance")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-rgl" ,r-rgl)))
    (home-page "https://cran.r-project.org/web/packages/tolerance/")
    (synopsis "Statistical tolerance intervals and regions")
    (description
     "This package provides functions for estimating tolerance
limits (intervals) for various univariate distributions (binomial, Cauchy,
discrete Pareto, exponential, two-parameter exponential, extreme value,
hypergeometric, Laplace, logistic, negative binomial, negative hypergeometric,
normal, Pareto, Poisson-Lindley, Poisson, uniform, and Zipf-Mandelbrot),
Bayesian normal tolerance limits, multivariate normal tolerance regions,
nonparametric tolerance intervals, tolerance bands for regression
settings (linear regression, nonlinear regression, nonparametric regression,
and multivariate regression), and analysis of variance tolerance intervals.
Visualizations are also available for most of these settings.")
    (license license:gpl2+)))

(define-public r-additivitytests
  (package
    (name "r-additivitytests")
    (version "1.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "additivityTests" version))
       (sha256
        (base32
         "048ds90wqjdjy1nyhna3m06asdklbh8sx1n556kss2j1r1pma1sw"))))
    (properties
     `((upstream-name . "additivityTests")))
    (build-system r-build-system)
    (home-page "https://github.com/simecek/additivityTests")
    (synopsis "Additivity tests in the two way Anova with single sub-class numbers")
    (description
     "This package provides an implementation of the Tukey, Mandel,
Johnson-Graybill, LBI, Tusell and modified Tukey non-additivity tests.")
    (license license:gpl3)))

(define-public r-flexclust
  (package
    (name "r-flexclust")
    (version "1.4-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flexclust" version))
       (sha256
        (base32
         "0x7wxk8y46ndyz6fdacym0rd6p9wh3pcfr28chjcg5d7fm849zl2"))))
    (properties `((upstream-name . "flexclust")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-class" ,r-class)
       ("r-lattice" ,r-lattice)
       ("r-modeltools" ,r-modeltools)))
    (home-page "https://cran.r-project.org/web/packages/flexclust/")
    (synopsis "Flexible cluster algorithms")
    (description
     "The main function @code{kcca} implements a general framework for
k-centroids cluster analysis supporting arbitrary distance measures and
centroid computation.  Further cluster methods include hard competitive
learning, neural gas, and QT clustering.  There are numerous visualization
methods for cluster results (neighborhood graphs, convex cluster hulls,
barcharts of centroids, ...), and bootstrap methods for the analysis of
cluster stability.")
    (license license:gpl2)))

(define-public r-biclust
  (package
    (name "r-biclust")
    (version "2.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "biclust" version))
       (sha256
        (base32
         "1pk7mvwlg4hkc4cn4w6wr2c192qx03d1xfwlzclk5bw1nmcg483b"))))
    (properties `((upstream-name . "biclust")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-additivitytests" ,r-additivitytests)
       ("r-colorspace" ,r-colorspace)
       ("r-flexclust" ,r-flexclust)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://cran.r-project.org/web/packages/biclust/")
    (synopsis "BiCluster algorithms")
    (description
     "The main function @code{biclust()} provides several algorithms to find
biclusters in two-dimensional data, spectral, plaid model, xmotifs, and bimax.
In addition, the package provides methods for data
preprocessing (normalization and discretization), visualization, and
validation of bicluster solutions.")
    (license license:gpl3)))

(define-public r-icge
  (package
    (name "r-icge")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ICGE" version))
       (sha256
        (base32
         "0xin7zml1nbygyi08hhg3wwr2jr1zcsvrlgia89zp4xanxlzgaqa"))))
    (properties `((upstream-name . "ICGE")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cluster" ,r-cluster)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ICGE/")
    (synopsis "Cluster estimation and identification of atypical units")
    (description
     "ICGE is a package that helps to estimate the number of real clusters in
data as well as to identify atypical units.  The underlying methods are based
on distances rather than on unit x variables.")
    (license license:gpl2+)))

(define-public r-depth
  (package
    (name "r-depth")
    (version "2.1-1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "depth" version))
       (sha256
        (base32
         "0szy0027nh4ps1z919i740i50app5q7cfyg1fj7pdyl45nbl8k6m"))))
    (properties `((upstream-name . "depth")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)
       ("r-circular" ,r-circular)
       ("r-rgl" ,r-rgl)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/depth/")
    (synopsis "Nonparametric depth functions for multivariate analysis")
    (description
     "This package provides tools for depth functions methodology applied to
multivariate analysis.  Besides allowing calculation of depth values and
depth-based location estimators, the package includes functions or drawing
contour plots and perspective plots of depth functions.  Euclidian and
spherical depths are supported.")
    (license license:gpl2)))

(define-public r-archetypes
  (package
    (name "r-archetypes")
    (version "2.2-0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "archetypes" version))
       (sha256
        (base32
         "0ibxsr173ib77gjhid91m85s8gjii4mi2w3d52q5301igv20p7r0"))))
    (properties `((upstream-name . "archetypes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-modeltools" ,r-modeltools)
       ("r-nnls" ,r-nnls)))
    (home-page "https://cran.r-project.org/web/packages/archetypes")
    (synopsis "Archetypal analysis")
    (description
     "The main function @code{archetypes} implements a framework for
archetypal analysis supporting arbitrary problem solving mechanisms for the
different conceptual parts of the algorithm.")
    (license license:gpl2+)))

(define-public r-shapes
  (package
    (name "r-shapes")
    (version "1.2.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shapes" version))
       (sha256
        (base32
         "0gfpdydfysp5mwg7qmkn73s67gvh2szb40mzqrx97h41ijgcgd8s"))))
    (properties `((upstream-name . "shapes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-minpack-lm" ,r-minpack-lm)
       ("r-rgl" ,r-rgl)
       ("r-scatterplot3d" ,r-scatterplot3d)))
    (home-page "http://www.maths.nottingham.ac.uk/~ild/shapes")
    (synopsis "Statistical shape analysis")
    (description
     "This package provides routines for the statistical analysis of landmark
shapes, including Procrustes analysis, graphical displays, principal
components analysis, permutation and bootstrap tests, thin-plate spline
transformation grids and comparing covariance matrices.  See Dryden, I.L.  and
Mardia, K.V. (2016).  Statistical shape analysis, with Applications in R (2nd
Edition), John Wiley and Sons.")
    (license license:gpl2)))

(define-public r-anthropometry
  (package
    (name "r-anthropometry")
    (version "1.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Anthropometry" version))
       (sha256
        (base32
         "1f568ri1s6psaby8y737vrkarbjg64v89d4jyw23hy17apdmszr8"))))
    (properties `((upstream-name . "Anthropometry")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-archetypes" ,r-archetypes)
       ("r-biclust" ,r-biclust)
       ("r-cluster" ,r-cluster)
       ("r-depth" ,r-depth)
       ("r-fnn" ,r-fnn)
       ("r-icge" ,r-icge)
       ("r-nnls" ,r-nnls)
       ("r-rgl" ,r-rgl)
       ("r-shapes" ,r-shapes)))
    (home-page "https://cran.r-project.org/web/packages/Anthropometry/")
    (synopsis "Statistical methods for anthropometric data")
    (description
     "This package provides statistical methods especially developed to
analyze anthropometric data.  These methods are aimed at providing effective
solutions to some commons problems related to Ergonomics and Anthropometry.
They are based on clustering, the statistical concept of data depth,
statistical shape analysis and archetypal analysis.")
    (license license:gpl2+)))

(define-public r-adamethods
  (package
    (name "r-adamethods")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adamethods" version))
       (sha256
        (base32
         "0mp73zh5x6h18gv29v981kb9n632kb58lvlcxwr6vcvrx393nrxh"))))
    (properties `((upstream-name . "adamethods")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-anthropometry" ,r-anthropometry)
       ("r-archetypes" ,r-archetypes)
       ("r-fnn" ,r-fnn)
       ("r-foreach" ,r-foreach)
       ("r-nnls" ,r-nnls)
       ("r-tolerance" ,r-tolerance)
       ("r-univoutl" ,r-univoutl)))
    (home-page "https://cran.r-project.org/web/packages/adamethods/")
    (synopsis "Archetypoid algorithms and anomaly detection")
    (description
     "This package is a collection of several algorithms to obtain
archetypoids with small and large databases and with both classical
multivariate data and functional data (univariate and multivariate).  Some of
these algorithms also allow to detect anomalies (outliers).")
    (license license:gpl2+)))

(define-public r-idpmisc
  (package
    (name "r-idpmisc")
    (version "1.1.20")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "IDPmisc" version))
       (sha256
        (base32
         "0zy6mxqa8arq0vvhsdcifzm3085c23rnwa1n36fhircph1xwvfdw"))))
    (properties `((upstream-name . "IDPmisc")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)))
    (home-page "https://cran.r-project.org/web/packages/IDPmisc/")
    (synopsis "Functions for data analyses and visualization")
    (description
     "This package provides different high-level graphics functions for
displaying large datasets, displaying circular data in a very flexible way,
finding local maxima, brewing color ramps, drawing nice arrows, zooming
2D-plots, creating figures with differently colored margin and plot region.
In addition, the package contains auxiliary functions for data manipulation
like omitting observations with irregular values or selecting data by logical
vectors, which include NAs.  Other functions are especially useful in
spectroscopy and analyses of environmental data: robust baseline fitting,
finding peaks in spectra, converting humidity measures.")
    (license license:gpl3+)))

(define-public r-qqman
  (package
    (name "r-qqman")
    (version "0.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "qqman" version))
       (sha256
        (base32
         "1v9s9ag1hfb47py87wb2nad4mbsfx35832hdmrh5kxrb2f11zl1s"))))
    (properties `((upstream-name . "qqman")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-calibrate" ,r-calibrate)))
    (home-page "https://cran.r-project.org/web/packages/qqman/")
    (synopsis "Q-Q and Manhattan plots for GWAS data")
    (description
     "This package allows you to create Q-Q and Manhattan plots for GWAS data
from PLINK results.")
    (license license:gpl3)))

(define-public r-ggplot-multistats
  (package
    (name "r-ggplot-multistats")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggplot.multistats" version))
       (sha256
        (base32
         "1afzfa86vc484bcwpg7m1ky03jpax584rigzgai8w06pifkmz0il"))))
    (properties
     `((upstream-name . "ggplot.multistats")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-hexbin" ,r-hexbin)
       ("r-rlang" ,r-rlang)
       ("r-scales" ,r-scales)))
    (home-page "https://github.com/flying-sheep/ggplot.multistats")
    (synopsis "Multiple summary statistics for binned stats/geometries")
    (description
     "This package provides the ggplot binning layer @code{stat_summaries_hex()},
which functions similar to its singular form, but allows the use of multiple
statistics per bin.  Those statistics can be mapped to multiple bin
aesthetics.")
    (license license:gpl3)))

(define-public r-knn-covertree
  (package
    (name "r-knn-covertree")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "knn.covertree" version))
       (sha256
        (base32
         "0msfcmwydws7q7m5jdb0dxab0nkbl7mq5llg6v3r4qrnlvrdggvz"))))
    (properties `((upstream-name . "knn.covertree")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "https://github.com/flying-sheep/knn.covertree")
    (synopsis "Accurate kNN Implementation with multiple distance measures")
    (description
     "Similarly to the FNN package, this package allows calculation of the k
nearest neighbors (kNN) of a data matrix.  The implementation is based on
cover trees introduced by Alina Beygelzimer, Sham Kakade, and John
Langford (2006) @url{doi:10.1145/1143844.1143857}.")
    (license license:agpl3+)))

(define-public r-poibin
  (package
    (name "r-poibin")
    (version "1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "poibin" version))
       (sha256
        (base32
         "1sxryvwwz6ldsnkzdy56p8c895s5yvpcai9ndyjv1x5q3l05wf9v"))))
    (properties `((upstream-name . "poibin")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/poibin/")
    (synopsis "Poisson binomial distribution")
    (description
     "This package provides an implementation of both the exact and
approximation methods for computing the @dfn{cumulative distribution
function} (CDF) of the Poisson binomial distribution.  It also provides the
@dfn{probability mass function} (PMF), quantile function, and random number
generation for the Poisson binomial distribution.")
    (license license:gpl2)))

(define-public r-diagram
  (package
    (name "r-diagram")
    (version "1.6.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "diagram" version))
       (sha256
        (base32
         "0f6ffprn5k0ir1s7m9s7izc64aa17r3gnygagz5bihrlsvawaavw"))))
    (properties `((upstream-name . "diagram")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-shape" ,r-shape)))
    (home-page "https://cran.r-project.org/web/packages/diagram/")
    (synopsis "Visualize simple graphs (networks) and plot flow diagrams")
    (description
     "This package provides tools to visualize simple graphs (networks) based
on a transition matrix, utilities to plot flow diagrams, visualizing webs,
electrical networks, etc.  It also includes supporting material for the book
\"A practical guide to ecological modelling - using R as a simulation
platform\" by Karline Soetaert and Peter M.J. Herman (2009) and the book
\"Solving Differential Equations in R\" by Karline Soetaert, Jeff Cash and
Francesca Mazzia (2012).")
    (license license:gpl2+)))

(define-public r-lim
  (package
    (name "r-lim")
    (version "1.4.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "LIM" version))
       (sha256
        (base32
         "03x1gnm06bw1wrzc01110bjzd2mvjdzbc2mbrazh22jrmb32w5d8"))))
    (properties `((upstream-name . "LIM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-diagram" ,r-diagram)
       ("r-limsolve" ,r-limsolve)))
    (home-page "https://cran.r-project.org/web/packages/LIM/")
    (synopsis "Linear inverse model examples and solution methods")
    (description
     "This package provides functions that read and solve linear inverse
problems (food web problems, linear programming problems).")
    (license license:gpl2+)))

(define-public r-shinycssloaders
  (package
    (name "r-shinycssloaders")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinycssloaders" version))
       (sha256
        (base32
         "1gzq1lhcnhqd145ys3ixf0l13l560fiqr2sc3m2nrijwxlgcw54d"))))
    (properties
     `((upstream-name . "shinycssloaders")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-glue" ,r-glue)
       ("r-shiny" ,r-shiny)))
    (home-page "https://github.com/andrewsali/shinycssloaders")
    (synopsis "Add CSS loading animations to Shiny outputs")
    (description
     "This package provides tools to create a lightweight Shiny wrapper for
the css-loaders created by Luke Hass
@url{https://github.com/lukehaas/css-loaders}.  Wrapping a Shiny output will
automatically show a loader when the output is (re)calculating.")
    (license license:gpl3)))

(define-public r-rsvg
  (package
    (name "r-rsvg")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rsvg" version))
       (sha256
        (base32
         "11mccgf6hfskg45wqc114sx3qy2r494y6axdf73z6xwhs1wpm97g"))))
    (properties `((upstream-name . "rsvg")))
    (build-system r-build-system)
    (inputs
     `(("librsvg" ,librsvg)
       ("zlib" ,zlib)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/jeroen/rsvg#readme")
    (synopsis "Render SVG images into PDF, PNG, PostScript, or Bitmap arrays")
    (description
     "This package allows you to render vector-based SVG images into
high-quality custom-size bitmap arrays using the librsvg2 library.  The
resulting bitmap can be written to e.g. PNG, JPEG or WEBP format.  In
addition, the package can convert images directly to various formats such as
PDF or PostScript.")
    (license license:expat)))

(define-public r-influencer
  (package
    (name "r-influencer")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "influenceR" version))
       (sha256
        (base32
         "12p9362hkndlnz1rd8j2rykg57kbm6l7ks60by3rd25xg50k5jag"))))
    (properties `((upstream-name . "influenceR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)
       ("r-matrix" ,r-matrix)))
    (home-page "https://github.com/rcc-uchicago/influenceR")
    (synopsis "Tools to quantify structural importance of nodes in a network")
    (description
     "This package provides functionality to compute various node centrality
measures on networks.  Included are functions to compute betweenness
centrality (by utilizing Madduri and Bader's SNAP library), implementations of
Burt's constraint and @dfn{effective network size} (ENS) metrics, Borgatti's
algorithm to identify key players, and Valente's bridging metric.  The
betweenness, Key Players, and bridging implementations are parallelized with
OpenMP.")
    (license license:gpl2)))

(define-public r-emplik
  (package
    (name "r-emplik")
    (version "1.0-4.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "emplik" version))
       (sha256
        (base32
         "1g4hz85bvw29c77zs0ig487z92jjl682vv457x81l077h0psvk7c"))))
    (properties `((upstream-name . "emplik")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quantreg" ,r-quantreg)))
    (home-page "https://www.ms.uky.edu/~mai/EmpLik.html")
    (synopsis "Empirical likelihood ratio for censored/truncated data")
    (description
     "This package provides empirical likelihood ratio tests for
means/quantiles/hazards from possibly censored and/or truncated data.  It also
does regression.")
    (license license:gpl2+)))

(define-public r-imputeyn
  (package
    (name "r-imputeyn")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "imputeYn" version))
       (sha256
        (base32
         "1b21w1aa5f7yiq8k0wa86wvbg4ij7f6ldwn6asfqwb0b90rvsgvs"))))
    (properties `((upstream-name . "imputeYn")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-emplik" ,r-emplik)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-quadprog" ,r-quadprog)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/imputeYn/")
    (synopsis "Impute last largest censored observation under weighted least squares")
    (description
     "This package allows for the imputation of the last largest censored
observantions.  This method brings less bias and more efficient estimates for
AFT models.")
    (license license:gpl2)))

(define-public r-adapenetclass
  (package
    (name "r-adapenetclass")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AdapEnetClass" version))
       (sha256
        (base32
         "01k3mj4g1ckbng7wkzzn9h0k9yf01cpnnkly0sjda574c5jhj0rc"))))
    (properties `((upstream-name . "AdapEnetClass")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-glmnet" ,r-glmnet)
       ("r-imputeyn" ,r-imputeyn)
       ("r-lars" ,r-lars)
       ("r-quadprog" ,r-quadprog)))
    (home-page "https://cran.r-project.org/web/packages/AdapEnetClass/")
    (synopsis "Class of adaptive elastic net methods for censored data")
    (description
     "This package provides methods for variable selection for AFT models.")
    (license license:gpl2)))

(define-public r-flock
  (package
    (name "r-flock")
    (version "0.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flock" version))
       (sha256
        (base32
         "1zg93p74icj4bhxnmnssj2xp6vw4yaksyavq03497v33xfpdxss7"))))
    (properties `((upstream-name . "flock")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/flock/")
    (synopsis "Process synchronization using file locks")
    (description
     "This package implements synchronization between R processes (spawned by
using the @code{parallel} package for instance) using file locks.  It supports
both exclusive and shared locking.")
    (license license:asl2.0)))

(define-public r-archivist
  (package
    (name "r-archivist")
    (version "2.3.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "archivist" version))
       (sha256
        (base32
         "1i11hrcq1910jgd6diw6h3sxx624v57zjianm49pqvb2dvd0b8y7"))))
    (properties `((upstream-name . "archivist")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dbi" ,r-dbi)
       ("r-digest" ,r-digest)
       ("r-flock" ,r-flock)
       ("r-httr" ,r-httr)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-rcurl" ,r-rcurl)
       ("r-rsqlite" ,r-rsqlite)))
    (home-page "https://pbiecek.github.io/archivist/")
    (synopsis "Tools for storing, restoring and searching for R objects")
    (description
     "Data exploration and modelling is a process in which a lot of data
artifacts are produced.  Artifacts like: subsets, data aggregates, plots,
statistical models, different versions of data sets and different versions of
results.  Archivist helps to store and manage artifacts created in R.  It
allows you to store selected artifacts as binary files together with their
metadata and relations.  Archivist allows sharing artifacts with others.  It
can look for already created artifacts by using its class, name, date of the
creation or other properties.  It also makes it easy to restore such
artifacts.")
    (license license:gpl2)))

(define-public r-versions
  (package
    (name "r-versions")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "versions" version))
       (sha256
        (base32
         "0zm49j785dgv7fyr1yl9q5f0dsk8hhpim5q5bpkgrkzv7pwjribd"))))
    (properties `((upstream-name . "versions")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/versions/")
    (synopsis "Query and install specific versions of CRAN packages")
    (description
     "This package allows you to install specified versions of R packages
hosted on CRAN and provides functions to list available versions and the
versions of currently installed packages.")
    (license license:bsd-3)))

(define-public r-adapr
  (package
    (name "r-adapr")
    (version "2.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adapr" version))
       (sha256
        (base32
         "1s57jdbi5pik56xjz1d4438ax6cywg2yq2s47h5g6wrwvpgr1qfw"))))
    (properties `((upstream-name . "adapr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-archivist" ,r-archivist)
       ("r-devtools" ,r-devtools)
       ("r-digest" ,r-digest)
       ("r-doparallel" ,r-doparallel)
       ("r-gdata" ,r-gdata)
       ("r-ggplot2" ,r-ggplot2)
       ("r-git2r" ,r-git2r)
       ("r-igraph" ,r-igraph)
       ("r-knitr" ,r-knitr)
       ("r-plotly" ,r-plotly)
       ("r-plyr" ,r-plyr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-shiny" ,r-shiny)
       ("r-shinydashboard" ,r-shinydashboard)
       ("r-versions" ,r-versions)))
    (home-page "https://cran.r-project.org/web/packages/adapr/")
    (synopsis "Implementation of an accountable data analysis process")
    (description
     "This package tracks reading and writing within R scripts that are
organized into a directed acyclic graph.  It contains an interactive Shiny
application @code{adaprApp()}.  It uses Git and file hashes to track version
histories of inputs and outputs.")
    (license license:lgpl2.0)))

(define-public r-adapsamp
  (package
    (name "r-adapsamp")
    (version "1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AdapSamp" version))
       (sha256
        (base32
         "1jayjrsiib2ij4rxxj59g71r3xhzl5yqh0lhi8k6cfy03i7dkvis"))))
    (properties `((upstream-name . "AdapSamp")))
    (build-system r-build-system)
    (propagated-inputs `(("r-pracma" ,r-pracma)))
    (home-page "https://cran.r-project.org/web/packages/AdapSamp/")
    (synopsis "Adaptive sampling algorithms")
    (description
     "For distributions whose probability density functions are log-concave,
the adaptive rejection sampling algorithm can be used to build envelope
functions for sampling.  For others, the modified adaptive rejection sampling
algorithm, the concave-convex adaptive rejection sampling algorithm, and the
adaptive slice sampling algorithm can be used.  This R package mainly includes
these four functions: @code{rARS()}, @code{rMARS()}, @code{rCCARS()}, and
@code{rASS()}.  These functions can realize sampling based on the algorithms
above.")
    (license license:gpl2)))

(define-public r-adaptalint
  (package
    (name "r-adaptalint")
    (version "0.2.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adaptalint" version))
       (sha256
        (base32
         "15qdcvnnbgcps8j5k79354wsc9alswijv8lcafg2i3lghaw536yf"))))
    (properties `((upstream-name . "adaptalint")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-lintr" ,r-lintr)
       ("r-purrr" ,r-purrr)))
    (home-page "https://cran.r-project.org/web/packages/adaptalint/")
    (synopsis "Check R code style")
    (description
     "This package provides tools to infer the code style (which style rules
are followed and which ones are not) from one package and use it to check
another.  This makes it easier to find and correct the most important problems
first.")
    (license license:gpl3)))

(define-public r-fracdiff
  (package
    (name "r-fracdiff")
    (version "1.5-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fracdiff" version))
       (sha256
        (base32
         "1dhfjlhr9sb38qgpsx0sm73l9lgc13d0fk32l7fmjfnalhr3n45q"))))
    (properties `((upstream-name . "fracdiff")))
    (build-system r-build-system)
    (home-page "https://github.com/mmaechler/fracdiff")
    (synopsis
     "Fractionally differenced ARIMA aka ARFIMA(P,d,q) models")
    (description
     "This package provides tools for the maximum likelihood estimation of the
parameters of a fractionally differenced ARIMA(p,d,q) model (Haslett and
Raftery, Appl.Statistics, 1989); it includes inference and basic methods.")
    (license license:gpl2+)))

(define-public r-forecast
  (package
    (name "r-forecast")
    (version "8.11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "forecast" version))
       (sha256
        (base32
         "0ayidhnk9cxav2qi83jrvqlg2jh4zlf4lki4xw48gdqsmjvih9x1"))))
    (properties `((upstream-name . "forecast")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colorspace" ,r-colorspace)
       ("r-fracdiff" ,r-fracdiff)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lmtest" ,r-lmtest)
       ("r-magrittr" ,r-magrittr)
       ("r-nnet" ,r-nnet)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-timedate" ,r-timedate)
       ("r-tseries" ,r-tseries)
       ("r-urca" ,r-urca)
       ("r-zoo" ,r-zoo)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))           ; needed for vignettes
    (home-page "https://pkg.robjhyndman.com/forecast/")
    (synopsis "Forecasting functions for time series and linear models")
    (description
     "This package provides methods and tools for displaying and analysing
univariate time series forecasts including exponential smoothing via state
space models and automatic ARIMA modelling.")
    (license license:gpl3)))

(define-public r-xmisc
  (package
    (name "r-xmisc")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Xmisc" version))
       (sha256
        (base32
         "11gwlcyxhz1p50m68cnqrxmisdk99v8vrsbvyr7k67f0kvsznzs1"))))
    (properties `((upstream-name . "Xmisc")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/package=Xmisc")
    (synopsis
     "Xiaobei's miscellaneous classes and functions")
    (description
     "This package provides Xiaobei's miscellaneous classes and functions,
which are useful when developing R packages for @dfn{object oriented
programming} (OOP) using R Reference Class.")
    (license license:gpl2+)))

(define-public r-proxyc
  (package
    (name "r-proxyc")
    (version "0.1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "proxyC" version))
       (sha256
        (base32
         "159bc42x4shm6n3rh9fc8ziv3ivq0ipmpbasrh279hhn1prc8gg6"))))
    (properties `((upstream-name . "proxyC")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rcppparallel" ,r-rcppparallel)))
    (home-page "https://cran.r-project.org/package=proxyC")
    (synopsis "Compute proximity in large sparse matrices")
    (description
     "This package provides efficient tools to compute the proximity between
rows or columns of large matrices.  Functions are optimised for large sparse
matrices using the Armadillo and Intel TBB libraries.  Among several built-in
similarity/distance measures, computation of correlation, cosine similarity
and Euclidean distance is particularly fast.")
    (license license:gpl3)))

(define-public r-isocodes
  (package
    (name "r-isocodes")
    (version "2020.03.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ISOcodes" version))
       (sha256
        (base32
         "1hz1sj57qkkkrgn8slsz2n4jv1fkyp40503j9rg30lxy4gmb83hn"))))
    (properties `((upstream-name . "ISOcodes")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/package=ISOcodes")
    (synopsis "Selected ISO codes")
    (description
     "This package provides ISO language, territory, currency, script and
character codes.  It provides ISO 639 language codes, ISO 3166 territory
codes, ISO 4217 currency codes, ISO 15924 script codes, and the ISO 8859
character codes as well as the UN M.49 area codes.")
    (license license:gpl2)))

(define-public r-stopwords
  (package
    (name "r-stopwords")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "stopwords" version))
       (sha256
        (base32
         "1nmi0bpd0c238g5b8ch1v034m5ng9llhs519cgxdrj3sh9fplwlv"))))
    (properties `((upstream-name . "stopwords")))
    (build-system r-build-system)
    (propagated-inputs `(("r-isocodes" ,r-isocodes)))
    (home-page "https://github.com/quanteda/stopwords")
    (synopsis "Multilingual stopword lists")
    (description
     "This package provides multiple sources of stopwords, for use in text
analysis and natural language processing.")
    (license license:expat)))

(define-public r-spacyr
  (package
    (name "r-spacyr")
    (version "1.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "spacyr" version))
       (sha256
        (base32
         "1b2ccgwsiqkvp7w37x8k7699c676q16vfrybkrfvyczyhki4s6nw"))))
    (properties `((upstream-name . "spacyr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-reticulate" ,r-reticulate)))
    (home-page "https://spacyr.quanteda.io")
    (synopsis "R wrapper for the spaCy NLP library")
    (description
     "This package provides an R wrapper to the Python @dfn{natural language
processing} (NLP) library @code{spaCy}, from @url{http://spacy.io}.")
    (license license:gpl3)))

(define-public r-snowballc
  (package
    (name "r-snowballc")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SnowballC" version))
       (sha256
        (base32
         "0b7pqdavf5jbf8si4ybnii5fff39p3b1rb5rym05j8s48hs7sqb1"))))
    (properties `((upstream-name . "SnowballC")))
    (build-system r-build-system)
    (home-page "https://r-forge.r-project.org/projects/r-temis/")
    (synopsis "Snowball stemmers based on the C libstemmer UTF-8 library")
    (description
     "This package provides an R interface to the C @code{libstemmer} library
that implements Porter's word stemming algorithm for collapsing words to a
common root to aid comparison of vocabulary.  Currently supported languages
are Danish, Dutch, English, Finnish, French, German, Hungarian, Italian,
Norwegian, Portuguese, Romanian, Russian, Spanish, Swedish and Turkish.")
    (license license:bsd-3)))

(define-public r-quanteda
  (package
    (name "r-quanteda")
    (version "2.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "quanteda" version))
       (sha256
        (base32
         "0pym6vdzqbkyj87m3pla229092xvvx4j830x67qflxzzdmc9dzhz"))))
    (properties `((upstream-name . "quanteda")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-extrafont" ,r-extrafont)
       ("r-fastmatch" ,r-fastmatch)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-jsonlite" ,r-jsonlite)
       ("r-magrittr" ,r-magrittr)
       ("r-matrix" ,r-matrix)
       ("r-network" ,r-network)
       ("r-proxyc" ,r-proxyc)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rcppparallel" ,r-rcppparallel)
       ("r-sna" ,r-sna)
       ("r-snowballc" ,r-snowballc)
       ("r-stopwords" ,r-stopwords)
       ("r-stringi" ,r-stringi)
       ("r-xml2" ,r-xml2)
       ("r-yaml" ,r-yaml)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://quanteda.io")
    (synopsis "Quantitative analysis of textual data")
    (description
     "This package provides a fast, flexible, and comprehensive framework for
quantitative text analysis in R.  It provides functionality for corpus
management, creating and manipulating tokens and ngrams, exploring keywords in
context, forming and manipulating sparse matrices of documents by features and
feature co-occurrences, analyzing keywords, computing feature similarities and
distances, applying content dictionaries, applying supervised and unsupervised
machine learning, visually representing text and text analyses, and more.")
    (license license:gpl3)))

(define-public r-topicmodels
  (package
    (name "r-topicmodels")
    (version "0.2-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "topicmodels" version))
       (sha256
        (base32
         "1757r5x8bsl4dk106xg6481mvdkdz9vwg87n7rpbvdkavsvhyxs0"))))
    (properties `((upstream-name . "topicmodels")))
    (build-system r-build-system)
    (native-inputs
     `(("gsl" ,gsl)))
    (propagated-inputs
     `(("r-modeltools" ,r-modeltools)
       ("r-slam" ,r-slam)
       ("r-tm" ,r-tm)))
    (home-page "https://cran.r-project.org/package=topicmodels")
    (synopsis "Topic models")
    (description
     "This package provides an interface to the C code for @dfn{Latent
Dirichlet Allocation} (LDA) models and @dfn{Correlated Topics Models} (CTM) by
David M. Blei and co-authors and the C++ code for fitting LDA models using
Gibbs sampling by Xuan-Hieu Phan and co-authors.")
    (license license:gpl2)))

(define-public r-stm
  (package
    (name "r-stm")
    (version "1.3.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "stm" version))
       (sha256
        (base32
         "1yyfxaxqc6yq0yq68zhdnhpwpvsyp71dlmivn7zxixfmp932s6cn"))))
    (properties `((upstream-name . "stm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-glmnet" ,r-glmnet)
       ("r-lda" ,r-lda)
       ("r-matrix" ,r-matrix)
       ("r-matrixstats" ,r-matrixstats)
       ("r-quadprog" ,r-quadprog)
       ("r-quanteda" ,r-quanteda)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-slam" ,r-slam)
       ("r-stringr" ,r-stringr)))
    (home-page "http://www.structuraltopicmodel.com/")
    (synopsis "Estimation of the Structural Topic Model")
    (description
     "The @dfn{Structural Topic Model} (STM) allows researchers to estimate
topic models with document-level covariates.  The package also includes tools
for model selection, visualization, and estimation of topic-covariate
regressions.")
    (license license:expat)))

(define-public r-polycor
  (package
    (name "r-polycor")
    (version "0.7-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "polycor" version))
       (sha256
        (base32
         "0wzwzklflbhi8sv9m7ijwr16v9zmkk0j0v4pbcpf32f8lbn3psna"))))
    (properties `((upstream-name . "polycor")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://r-forge.r-project.org/projects/polycor/")
    (synopsis "Polychoric and polyserial correlations")
    (description
     "This package provides tools to compute polychoric and polyserial
correlations by quick \"two-step\" methods or ML, optionally with standard
errors; tetrachoric and biserial correlations are special cases.")
    (license license:gpl2+)))

(define-public r-msm
  (package
    (name "r-msm")
    (version "1.6.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "msm" version))
       (sha256
        (base32
         "1d32y8f0vb2dfv3999liigpns788j145nrvd1xpxb9i2lsg8mwgk"))))
    (properties `((upstream-name . "msm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-expm" ,r-expm)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-survival" ,r-survival)))
    (home-page "https://github.com/chjackson/msm")
    (synopsis "Multi-state Markov and hidden Markov models in continuous time")
    (description
     "This package provides functions for fitting continuous-time Markov and
hidden Markov multi-state models to longitudinal data.  It was designed for
processes observed at arbitrary times in continuous time (panel data) but some
other observation schemes are supported.  Both Markov transition rates and the
hidden Markov output process can be modelled in terms of covariates, which may
be constant or piecewise-constant in time.")
    (license license:gpl2+)))

(define-public r-ltm
  (package
    (name "r-ltm")
    (version "1.1-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ltm" version))
       (sha256
        (base32
         "1qrgzwx5l58qf5rfp1knxc84r0g943q5sdr3ky74zzwpnmrf2vf7"))))
    (properties `((upstream-name . "ltm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-msm" ,r-msm)
       ("r-polycor" ,r-polycor)))
    (home-page "https://github.com/drizopoulos/ltm")
    (synopsis "Latent trait models under IRT")
    (description
     "This is a package supporting the analysis of multivariate dichotomous
and polytomous data using latent trait models under the Item Response Theory
approach.  It includes the Rasch, the Two-Parameter Logistic, the Birnbaum's
Three-Parameter, the Graded Response, and the Generalized Partial Credit
Models.")
    (license license:gpl2+)))

(define-public r-mi
  (package
    (name "r-mi")
    (version "1.0")
    (source
      (origin
        (method url-fetch)
        (uri (cran-uri "mi" version))
        (sha256
          (base32
            "1h47k5mpbvhid83277dvvj2di493bgzz9iarpyv3r30y219l7x1l"))))
    (properties `((upstream-name . "mi")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-arm" ,r-arm)
       ("r-matrix" ,r-matrix)))
    (home-page "http://www.stat.columbia.edu/~gelman/")
    (synopsis "Missing data imputation and model checking")
    (description
     "This package provides functions for data manipulation, imputing missing
values in an approximate Bayesian framework, diagnostics of the models used to
generate the imputations, confidence-building mechanisms to validate some of
the assumptions of the imputation algorithm, and functions to analyze multiply
imputed data sets with the appropriate degree of sampling uncertainty.")
    (license license:gpl2+)))

(define-public r-matrixcalc
  (package
    (name "r-matrixcalc")
    (version "1.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "matrixcalc" version))
       (sha256
        (base32
         "1c4w9dhi5w98qj1wwh9bbpnfk39rhiwjbanalr8bi5nmxkpcmrhp"))))
    (properties `((upstream-name . "matrixcalc")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/matrixcalc/")
    (synopsis "Collection of functions for matrix calculations")
    (description
     "This package provides a collection of functions to support matrix
calculations for probability, econometric and numerical analysis.  There are
additional functions that are comparable to APL functions which are useful for
actuarial models such as pension mathematics.")
    (license license:gpl2+)))

(define-public r-sem
  (package
    (name "r-sem")
    (version "3.1-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sem" version))
       (sha256
        (base32
         "1f9c6g6pfx66gd2pappcsqh484ah6a0x4z47hpd46rah0817hcsa"))))
    (properties `((upstream-name . "sem")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-mass" ,r-mass)
       ("r-matrixcalc" ,r-matrixcalc)
       ("r-mi" ,r-mi)))
    (home-page "https://cran.r-project.org/package=sem")
    (synopsis "Structural equation models")
    (description
     "This package provides functions for fitting general linear structural
equation models (with observed and latent variables) using the RAM approach,
and for fitting structural equations in observed-variable models by two-stage
least squares.")
    (license license:gpl2+)))

(define-public r-semtools
  (package
    (name "r-semtools")
    (version "0.5-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "semTools" version))
       (sha256
        (base32
         "1zj841pszfsikzp82cmh463qyc4xhdrqjqcnhc2r8mcflv12irv6"))))
    (properties `((upstream-name . "semTools")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lavaan" ,r-lavaan)))
    (home-page "https://github.com/simsem/semTools/wiki")
    (synopsis "Useful tools for structural equation modeling")
    (description
     "This package provides useful tools for structural equation modeling.")
    (license license:gpl2+)))

(define-public r-regsem
  (package
    (name "r-regsem")
    (version "1.5.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "regsem" version))
       (sha256
        (base32
         "0ch057010xfsw0nqcsarzakdbiplvxaldyqlbbacspqs65ax1yk7"))))
    (properties `((upstream-name . "regsem")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lavaan" ,r-lavaan)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rsolnp" ,r-rsolnp)))
    (home-page "https://cran.r-project.org/package=regsem")
    (synopsis "Regularized structural equation modeling")
    (description
     "This package uses both ridge and lasso penalties (and extensions) to
penalize specific parameters in structural equation models.  The package
offers additional cost functions, cross validation, and other extensions
beyond traditional structural equation models.  It also contains a function to
perform @dfn{exploratory mediation} (XMed).")
    (license license:gpl2+)))

(define-public r-stanheaders
  (package
    (name "r-stanheaders")
    (version "2.19.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "StanHeaders" version))
       (sha256
        (base32
         "0cmk0fzczx7dcywcw1dhm6gfq84qlsx77qrsk4z3bf3dhr4bznam"))))
    (properties `((upstream-name . "StanHeaders")))
    (build-system r-build-system)
    (inputs `(("pandoc" ,ghc-pandoc)))
    (native-inputs
     `(("gfortran" ,gfortran)
       ("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://mc-stan.org/")
    (synopsis "C++ header files for Stan")
    (description
     "The C++ header files of the Stan project are provided by this package.
There is a shared object containing part of the @code{CVODES} library, but it
is not accessible from R.  @code{r-stanheaders} is only useful for developers
who want to utilize the @code{LinkingTo} directive of their package's
DESCRIPTION file to build on the Stan library without incurring unnecessary
dependencies.

The Stan project develops a probabilistic programming language that implements
full or approximate Bayesian statistical inference via Markov Chain Monte
Carlo or variational methods and implements (optionally penalized) maximum
likelihood estimation via optimization.  The Stan library includes an advanced
automatic differentiation scheme, templated statistical and linear algebra
functions that can handle the automatically differentiable scalar types (and
doubles, ints, etc.), and a parser for the Stan language.  The @code{r-rstan}
package provides user-facing R functions to parse, compile, test, estimate,
and analyze Stan models.")
    (license license:bsd-3)))

(define-public r-rpf
  (package
    (name "r-rpf")
    (version "1.0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rpf" version))
       (sha256
        (base32
         "1i2kqd7nx55nn35qnw89xmnqk23x9c8xhkh736c2xg7k2ai84ybl"))))
    (properties `((upstream-name . "rpf")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lifecycle" ,r-lifecycle)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "https://github.com/jpritikin/rpf")
    (synopsis "Response probability functions")
    (description
     "The purpose of this package is to factor out logic and math common to
Item Factor Analysis fitting, diagnostics, and analysis.  It is envisioned as
core support code suitable for more specialized IRT packages to build upon.
Complete access to optimized C functions is made available with
@code{R_RegisterCCallable()}.")
    (license license:gpl3+)))

(define-public r-openmx
  (package
    (name "r-openmx")
    (version "2.17.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "OpenMx" version))
       (sha256
        (base32
         "1s2pcg281ag3qz2wz8yi826f2d3kj3qg916js7zz0nsrljcyv5bc"))))
    (properties `((upstream-name . "OpenMx")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-digest" ,r-digest)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-rpf" ,r-rpf)
       ("r-stanheaders" ,r-stanheaders)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "http://openmx.ssri.psu.edu")
    (synopsis "Extended structural equation modelling")
    (description
     "This package allows for the estimation of a wide variety of advanced
multivariate statistical models.  It consists of a library of functions and
optimizers that allow you to quickly and flexibly define an SEM model and
estimate parameters given observed data.")
    (license license:asl2.0)))

(define-public r-kutils
  (package
    (name "r-kutils")
    (version "1.69")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kutils" version))
       (sha256
        (base32
         "12pg26a85h0jxlfcyai68dbh4bq1gnq8v1ngi8k9qvafbrpc6gx8"))))
    (properties `((upstream-name . "kutils")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-foreign" ,r-foreign)
       ("r-lavaan" ,r-lavaan)
       ("r-openxlsx" ,r-openxlsx)
       ("r-plyr" ,r-plyr)
       ("r-runit" ,r-runit)
       ("r-xtable" ,r-xtable)))
    (home-page "https://cran.r-project.org/package=kutils")
    (synopsis "Project management tools")
    (description
     "This package provides tools for data importation, recoding, and
inspection.  There are functions to create new project folders, R code
templates, create uniquely named output directories, and to quickly obtain a
visual summary for each variable in a data frame.  The main feature here is
the systematic implementation of the \"variable key\" framework for data
importation and recoding.")
    (license license:gpl2)))

(define-public r-rockchalk
  (package
    (name "r-rockchalk")
    (version "1.8.144")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rockchalk" version))
       (sha256
        (base32
         "07dp1n155b9gfvk8l30h6bhjbhbylsjxfzns08mryn4mxj3nqpnb"))))
    (properties `((upstream-name . "rockchalk")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cardata" ,r-cardata)
       ("r-kutils" ,r-kutils)
       ("r-lme4" ,r-lme4)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/package=rockchalk")
    (synopsis "Regression estimation and presentation")
    (description
     "This package provides a collection of functions for interpretation and
presentation of regression analysis.  These functions are used to produce the
statistics lectures in @url{http://pj.freefaculty.org/guides}.  The package
includes regression diagnostics, regression tables, and plots of interactions
and \"moderator\" variables.  The emphasis is on \"mean-centered\" and
\"residual-centered\" predictors.  The vignette @code{rockchalk} offers a
fairly comprehensive overview.")
    (license license:gpl3+)))

(define-public r-lisreltor
  (package
    (name "r-lisreltor")
    (version "0.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lisrelToR" version))
       (sha256
        (base32
         "0zicq0z3hhixan1p1apybnf3v5s6v6ysll4pcz8ivygwr2swv3p5"))))
    (properties `((upstream-name . "lisrelToR")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/package=lisrelToR")
    (synopsis "Import output from LISREL into R")
    (description
     "This is an unofficial package aimed at automating the import of LISREL
output in R.")
    (license license:gpl2)))

(define-public r-bdgraph
  (package
    (name "r-bdgraph")
    (version "2.62")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "BDgraph" version))
       (sha256
        (base32
         "1b1vfar940swvn3pcil848qsp8ji50fjjll8jjzp6y2adx0f8pby"))))
    (properties `((upstream-name . "BDgraph")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)))
    (home-page "https://www.uva.nl/profile/a.mohammadi")
    (synopsis "Bayesian structure learning in graphical models")
    (description
     "This package provides statistical tools for Bayesian structure learning
in undirected graphical models for continuous, discrete, and mixed data.  It
uses a trans-dimensional @dfn{Markov Chain Monte Carlo} (MCMC) approach based
on a continuous-time birth-death process.")
    (license license:gpl2+)))

(define-public r-d3network
  (package
    (name "r-d3network")
    (version "0.5.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "d3Network" version))
       (sha256
        (base32
         "1gh979z9wksyxxxdzlfzibn0ysvf6h1ij7vwpd55fvbwr308syaw"))))
    (properties `((upstream-name . "d3Network")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-plyr" ,r-plyr)
       ("r-rjson" ,r-rjson)
       ("r-whisker" ,r-whisker)))
    (home-page "http://christophergandrud.github.io/d3Network/")
    (synopsis "Create D3 JavaScript network, tree, dendrogram, and Sankey graphs")
    (description
     "This package is intended to make it easy to create D3 JavaScript
network, tree, dendrogram, and Sankey graphs from R using data frames.")
    (license license:gpl3+)))

(define-public r-qgraph
  (package
    (name "r-qgraph")
    (version "1.6.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "qgraph" version))
       (sha256
        (base32
         "0pwys9irxvp0ap158drplyypkplbmwqinv0fmlsblk7q875cr592"))))
    (properties `((upstream-name . "qgraph")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)
       ("r-bdgraph" ,r-bdgraph)
       ("r-colorspace" ,r-colorspace)
       ("r-corpcor" ,r-corpcor)
       ("r-d3network" ,r-d3network)
       ("r-dplyr" ,r-dplyr)
       ("r-fdrtool" ,r-fdrtool)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggraph" ,r-ggraph)
       ("r-glasso" ,r-glasso)
       ("r-gtools" ,r-gtools)
       ("r-hmisc" ,r-hmisc)
       ("r-huge" ,r-huge)
       ("r-igraph" ,r-igraph)
       ("r-jpeg" ,r-jpeg)
       ("r-lavaan" ,r-lavaan)
       ("r-matrix" ,r-matrix)
       ("r-pbapply" ,r-pbapply)
       ("r-plyr" ,r-plyr)
       ("r-png" ,r-png)
       ("r-psych" ,r-psych)
       ("r-rcpp" ,r-rcpp)
       ("r-reshape2" ,r-reshape2)
       ("r-tidygraph" ,r-tidygraph)))
    (home-page "http://sachaepskamp.com/qgraph/")
    (synopsis "Weighted network visualization and analysis")
    (description
     "This package implements tools for weighted network visualization and
analysis, as well as Gaussian graphical model computation.  It contains graph
plotting methods, and tools for psychometric data visualization and graphical
model estimation.  See Epskamp et al. (2012)
@url{doi:10.18637/jss.v048.i04}.")
    (license license:gpl2)))

(define-public r-semplot
  (package
    (name "r-semplot")
    (version "1.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "semPlot" version))
       (sha256
        (base32
         "0l1v9yi1pv59iwfknw4dh9qskk5y8r347jq1vq13gnfd3bmd71xr"))))
    (properties `((upstream-name . "semPlot")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colorspace" ,r-colorspace)
       ("r-corpcor" ,r-corpcor)
       ("r-igraph" ,r-igraph)
       ("r-lavaan" ,r-lavaan)
       ("r-lisreltor" ,r-lisreltor)
       ("r-openmx" ,r-openmx)
       ("r-plyr" ,r-plyr)
       ("r-qgraph" ,r-qgraph)
       ("r-regsem" ,r-regsem)
       ("r-rockchalk" ,r-rockchalk)
       ("r-sem" ,r-sem)
       ("r-xml" ,r-xml)))
    (home-page "https://github.com/SachaEpskamp/semPlot")
    (synopsis "Unified visualizations of structural equation models")
    (description
     "Structural equation modeling (SEM) has a long history of representing
models graphically as path diagrams.  The semPlot package for R fills the gap
between advanced, but time-consuming, graphical software and the limited
graphics produced automatically by SEM software.  In addition, semPlot offers
more functionality than drawing path diagrams: it can act as a common ground
for importing SEM results into R.  Any result usable as input to semPlot can
also be represented in any of the three popular SEM frame-works, as well as
translated to input syntax for the R packages @code{sem} and @code{lavaan}.")
    (license license:gpl2)))

(define-public r-cdm
  (package
    (name "r-cdm")
    (version "7.5-15")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "CDM" version))
       (sha256
        (base32
         "159ny2dz0rf1r3k1mqlfwambffc8rx425sggf5bn51nybpzanq3l"))))
    (properties `((upstream-name . "CDM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mvtnorm" ,r-mvtnorm)
       ("r-polycor" ,r-polycor)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page
     "https://github.com/alexanderrobitzsch/CDM")
    (synopsis "Cognitive diagnosis modeling")
    (description
     "This package provides functions for cognitive diagnosis modeling and
multidimensional item response modeling for dichotomous and polytomous item
responses.  It enables the estimation of the DINA and DINO model, the multiple
group (polytomous) GDINA model, the multiple choice DINA model, the general
diagnostic model (GDM), the structured latent class model (SLCA), and
regularized latent class analysis.  See George, Robitzsch, Kiefer, Gross, and
Uenlue (2017) @url{doi:10.18637/jss.v074.i02} for further details on
estimation and the package structure.  For tutorials on how to use the CDM
package see George and Robitzsch (2015, @url{doi:10.20982/tqmp.11.3.p189}) as
well as Ravand and Robitzsch (2015).")
    (license license:gpl2+)))

(define-public r-tam
  (package
    (name "r-tam")
    (version "3.4-26")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TAM" version))
       (sha256
        (base32
         "111d7qkxhwh1lfvldyh9d61pdb5vb6x8lr8n9h95ssvw07vjqvk9"))))
    (properties `((upstream-name . "TAM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cdm" ,r-cdm)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "http://www.edmeasurementsurveys.com/TAM/Tutorials/")
    (synopsis "Test analysis modules")
    (description
     "This package includes tools for marginal maximum likelihood estimation
and joint maximum likelihood estimation for unidimensional and
multidimensional item response models.  The package functionality covers the
Rasch model, 2PL model, 3PL model, generalized partial credit model,
multi-faceted Rasch model, nominal item response model, structured latent
class model, mixture distribution IRT models, and located latent class models.
Latent regression models and plausible value imputation are also supported.")
    (license license:gpl2+)))

(define-public r-erm
  (package
    (name "r-erm")
    (version "1.0-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "eRm" version))
       (sha256
        (base32
         "0njqzznnhnkvalmhiq5yq1w7gwp2myki5cv61w42ydvd27hdyyg9"))))
    (properties `((upstream-name . "eRm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colorspace" ,r-colorspace)
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-psych" ,r-psych)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/package=eRm")
    (synopsis "Extended Rasch modeling")
    (description
     "This package provides tools to fit @dfn{Rasch models} (RM), @dfn{linear
logistic test models} (LLTM), @dfn{rating scale model} (RSM), @dfn{linear
rating scale models} (LRSM), @dfn{partial credit models} (PCM), and
@dfn{linear partial credit models} (LPCM).  Missing values are allowed in the
data matrix.  Additional features are the ML estimation of the person
parameters, Andersen's LR-test, item-specific Wald test, Martin-Loef-Test,
nonparametric Monte-Carlo Tests, itemfit and personfit statistics including
infit and outfit measures, ICC and other plots, automated stepwise item
elimination, and a simulation module for various binary data matrices.")
    (license license:gpl3)))

(define-public r-irtoys
  (package
    (name "r-irtoys")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "irtoys" version))
       (sha256
        (base32
         "0h6iiaxikhbxhbyksbjnb09qdxinlkwr2v9yzs5wslbni14paq5q"))))
    (properties `((upstream-name . "irtoys")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ltm" ,r-ltm)
       ("r-sm" ,r-sm)))
    (home-page "https://cran.r-project.org/package=irtoys")
    (synopsis "Collection of functions related to Item Response Theory (IRT)")
    (description
     "This package provides a collection of functions useful in learning and
practicing @dfn{Item Response Theory} (IRT), which can be combined into larger
programs.  It provides basic CTT analysis, a simple common interface to the
estimation of item parameters in IRT models for binary responses with three
different programs (ICL, BILOG-MG, and ltm), ability estimation (MLE, BME,
EAP, WLE, plausible values), item and person fit statistics, scaling
methods (MM, MS, Stocking-Lord, and the complete Hebaera method), and a rich
array of parametric and non-parametric (kernel) plots.  It estimates and plots
Haberman's interaction model when all items are dichotomously scored.")
    (license license:gpl2+)))

(define-public r-iheatmapr
  (package
    (name "r-iheatmapr")
    (version "0.4.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "iheatmapr" version))
       (sha256
        (base32
         "0s479j9l35xiss599vablxgvg6i2j9zq9sxphsq4vdk3bafg84bw"))))
    (properties `((upstream-name . "iheatmapr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fastcluster" ,r-fastcluster)
       ("r-ggdendro" ,r-ggdendro)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-magrittr" ,r-magrittr)
       ("r-plyr" ,r-plyr)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-s4vectors" ,r-s4vectors)
       ("r-scales" ,r-scales)))
    (home-page "https://docs.ropensci.org/iheatmapr")
    (synopsis "Interactive, Complex Heatmaps")
    (description
     "iheatmapr is an R package for building complex, interactive heatmaps
using modular building blocks.  \"Complex\" heatmaps are heatmaps in which
subplots along the rows or columns of the main heatmap add more information
about each row or column.  For example, a one column additional heatmap may
indicate what group a particular row or column belongs to.  Complex heatmaps
may also include multiple side by side heatmaps which show different types of
data for the same conditions.  Interactivity can improve complex heatmaps by
providing tooltips with information about each cell and enabling zooming into
interesting features. iheatmapr uses the plotly library for interactivity.")
    (license license:expat)))

(define-public r-packrat
  (package
    (name "r-packrat")
    (version "0.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "packrat" version))
       (sha256
        (base32
         "1xy5dd2hrpqa07jfl4s7dsrya05mf36ms74j833scdz0zf89586n"))))
    (properties `((upstream-name . "packrat")))
    (build-system r-build-system)
    (home-page "https://github.com/rstudio/packrat/")
    (synopsis "Dependency management R projects")
    (description
     "This package provides a dependency manager for R projects that allows
you to manage the R packages your project depends on in an isolated, portable,
and reproducible way.")
    (license license:gpl2)))

(define-public r-rsconnect
  (package
    (name "r-rsconnect")
    (version "0.8.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rsconnect" version))
       (sha256
        (base32
         "05ii0p0p7xpf8z0c1594s5q7wpwcs7lmlddrd67s5p2ka5m8qwiz"))))
    (properties `((upstream-name . "rsconnect")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-digest" ,r-digest)
       ("r-jsonlite" ,r-jsonlite)
       ("r-openssl" ,r-openssl)
       ("r-packrat" ,r-packrat)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-yaml" ,r-yaml)))
    (home-page "https://github.com/rstudio/rsconnect")
    (synopsis "Deployment interface for R Markdown documents and Shiny applications")
    (description
     "This package provides a programmatic deployment interface for RPubs,
shinyapps.io, and RStudio Connect.  Supported content types include R Markdown
documents, Shiny applications, Plumber APIs, plots, and static web content.")
    (license license:gpl2)))

;; This package includes minified JavaScript files.  When upgrading please
;; check that there are no new minified JavaScript files.
(define-public r-dygraphs
  (package
    (name "r-dygraphs")
    (version "1.1.1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dygraphs" version))
       (sha256
        (base32
         "022j007mzfa9k2n31yg4aizcsf571vv3jip092h23rqj03rk3ly3"))))
    (properties `((upstream-name . "dygraphs")))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst/htmlwidgets/lib/"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `(("dygraphs/dygraph-combined-dev.js"
                         "dygraph-combined.js")
                        (,(assoc-ref inputs "js-jquery")
                         "jquery/jquery.min.js")
                        (,(assoc-ref inputs "js-fquarter")
                         "fquarter/moment-fquarter.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ;; They actually use version 1.11.1, but this more recent version
       ;; should be just fine.
       ("js-jquery"
        ,(origin
           (method url-fetch)
           (uri "https://code.jquery.com/jquery-1.12.4.js")
           (sha256
            (base32
             "0x9mrc1668icvhpwzvgafm8xm11x9lfai9nwr66aw6pjnpwkc3s3"))))
       ("js-fquarter"
        ,(origin
           (method url-fetch)
           (uri (string-append "https://raw.githubusercontent.com/robgallen/"
                               "moment-fquarter/1.0.1/moment-fquarter.js"))
           (sha256
            (base32
             "01mdnsaibm9jy2f1qpbn692hpv309lhj5si9nagib4dawmrkffij"))))))
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-magrittr" ,r-magrittr)
       ("r-xts" ,r-xts)
       ("r-zoo" ,r-zoo)))
    (home-page "https://github.com/rstudio/dygraphs")
    (synopsis "Interface to Dygraphs interactive time series charting library")
    (description
     "This package provides an R interface to the dygraphs JavaScript charting
library (a copy of which is included in the package).  It provides rich
facilities for charting time-series data in R, including highly configurable
series- and axis-display and interactive features like zoom/pan and
series/point highlighting.")
    (license license:expat)))

(define-public r-shinystan
  (package
    (name "r-shinystan")
    (version "2.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinystan" version))
       (sha256
        (base32
         "18alf5kiqw7y2l6m5nxxizwc2znsf9frxfsqhvgcad8hld9cbya5"))))
    (properties `((upstream-name . "shinystan")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayesplot" ,r-bayesplot)
       ("r-colourpicker" ,r-colourpicker)
       ("r-dt" ,r-dt)
       ("r-dygraphs" ,r-dygraphs)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-gtools" ,r-gtools)
       ("r-markdown" ,r-markdown)
       ("r-reshape2" ,r-reshape2)
       ("r-rsconnect" ,r-rsconnect)
       ("r-rstan" ,r-rstan)
       ("r-shiny" ,r-shiny)
       ("r-shinyjs" ,r-shinyjs)
       ("r-shinythemes" ,r-shinythemes)
       ("r-threejs" ,r-threejs)
       ("r-xtable" ,r-xtable)
       ("r-xts" ,r-xts)))
    (home-page "https://mc-stan.org/")
    (synopsis "Interactive visual and numerical analysis for Bayesian models")
    (description
     "This package provides a graphical user interface for interactive
@dfn{Markov chain Monte Carlo} (MCMC) diagnostics and plots and tables helpful
for analyzing a posterior sample.  The interface is powered by the Shiny web
application framework and works with the output of MCMC programs written in
any programming language (and has extended functionality for Stan models fit
using the @code{rstan} and @code{rstanarm} packages).")
    (license license:gpl3+)))

(define-public r-rstantools
  (package
    (name "r-rstantools")
    (version "2.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rstantools" version))
       (sha256
        (base32
         "1il0pn4ksbdkska5fmhvgaicvwnnc6cs08g6ags9fj1xkjiqmrsa"))))
    (properties `((upstream-name . "rstantools")))
    (build-system r-build-system)
    (inputs `(("pandoc" ,ghc-pandoc)))
    (propagated-inputs
     `(("r-desc" ,r-desc)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://mc-stan.org/rstantools/")
    (synopsis "Tools for developing R packages interfacing with Stan")
    (description
     "This package provides various tools for developers of R packages
interfacing with @url{https://mc-stan.org, Stan}, including functions to set
up the required package structure, S3 generics and default methods to unify
function naming across Stan-based R packages, and vignettes with
recommendations for developers.")
    (license license:gpl3+)))

(define-public r-loo
  (package
    (name "r-loo")
    (version "2.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "loo" version))
       (sha256
        (base32
         "1hq1zcj76x55z9kic6cwf7mfq9pzqfbr341jbc9wp7x8ac4zcva6"))))
    (properties `((upstream-name . "loo")))
    (build-system r-build-system)
    (inputs
     `(("pandoc" ,ghc-pandoc)
       ("pandoc-citeproc" ,ghc-pandoc-citeproc)))
    (propagated-inputs
     `(("r-checkmate" ,r-checkmate)
       ("r-matrixstats" ,r-matrixstats)))
    (home-page "https://mc-stan.org/loo/")
    (synopsis "Leave-One-Out cross-validation and WAIC for Bayesian models")
    (description
     "This package provides an implementation of efficient approximate
@dfn{leave-one-out} (LOO) cross-validation for Bayesian models fit using
Markov chain Monte Carlo, as described in @url{doi:10.1007/s11222-016-9696-4}.
The approximation uses @dfn{Pareto smoothed importance sampling} (PSIS), a new
procedure for regularizing importance weights.  As a byproduct of the
calculations, we also obtain approximate standard errors for estimated
predictive errors and for the comparison of predictive errors between models.
The package also provides methods for using stacking and other model weighting
techniques to average Bayesian predictive distributions.")
    (license license:gpl3+)))

(define-public r-rstan
  (package
    (name "r-rstan")
    (version "2.19.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rstan" version))
       (sha256
        (base32
         "128ndwjrhf8b1qvvqz4bl13qlm8718z9qs5ryc6gsdr3vk65s0np"))))
    (properties `((upstream-name . "rstan")))
    (build-system r-build-system)
    (arguments
     `(#:phases
       (modify-phases %standard-phases
         (add-before 'install 'set-timezone
           ;; This package is picky about timezones.
           (lambda* (#:key inputs #:allow-other-keys)
             (setenv "TZ" "UTC+1")
             (setenv "TZDIR"
                     (string-append (assoc-ref inputs "tzdata")
                                    "/share/zoneinfo"))
             #t)))))
    (native-inputs
     `(("tzdata" ,tzdata)
       ("pandoc" ,ghc-pandoc)))
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-inline" ,r-inline)
       ("r-loo" ,r-loo)
       ("r-pkgbuild" ,r-pkgbuild)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-stanheaders" ,r-stanheaders)))
    (home-page "https://discourse.mc-stan.org/")
    (synopsis "R interface to Stan")
    (description
     "User-facing R functions are provided to parse, compile, test, estimate,
and analyze Stan models by accessing the header-only Stan library provided by
the StanHeaders package.  The Stan project develops a probabilistic
programming language that implements full Bayesian statistical inference via
Markov Chain Monte Carlo, rough Bayesian inference via 'variational'
approximation, and (optionally penalized) maximum likelihood estimation via
optimization.  In all three cases, automatic differentiation is used to
quickly and accurately evaluate gradients without burdening the user with the
need to derive the partial derivatives.")
    (license license:gpl3+)))

(define-public r-rstanarm
  (package
    (name "r-rstanarm")
    (version "2.19.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rstanarm" version))
       (sha256
        (base32
         "0gxjq8bdlvdd8kn3dhp12xlymdab036r7n12lzmd3xlkl4cnxq3s"))))
    (properties `((upstream-name . "rstanarm")))
    (build-system r-build-system)
    (inputs
     `(("pandoc" ,ghc-pandoc)
       ("pandoc-citeproc" ,ghc-pandoc-citeproc)))
    (propagated-inputs
     `(("r-bayesplot" ,r-bayesplot)
       ("r-bh" ,r-bh)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lme4" ,r-lme4)
       ("r-loo" ,r-loo)
       ("r-matrix" ,r-matrix)
       ("r-nlme" ,r-nlme)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-rcppparallel" ,r-rcppparallel)
       ("r-rstan" ,r-rstan)
       ("r-rstantools" ,r-rstantools)
       ("r-shinystan" ,r-shinystan)
       ("r-stanheaders" ,r-stanheaders)
       ("r-survival" ,r-survival)))
    (home-page "https://mc-stan.org/rstanarm/")
    (synopsis "Bayesian applied regression modeling via Stan")
    (description
     "This package estimates previously compiled regression models using the
@code{rstan} package, which provides the R interface to the Stan C++ library
for Bayesian estimation.  Users specify models via the customary R syntax with
a formula and @code{data.frame} plus some additional arguments for priors.")
    (license license:gpl3+)))

(define-public r-kendall
  (package
    (name "r-kendall")
    (version "2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Kendall" version))
       (sha256
        (base32
         "0z2yr3x2nvdm81w2imb61hxwcbmg14kfb2bxgh3wmkmv3wfjwkwn"))))
    (properties `((upstream-name . "Kendall")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/Kendall/")
    (synopsis "Kendall rank correlation and Mann-Kendall trend test")
    (description
     "This package computes the Kendall rank correlation and Mann-Kendall
trend test.")
    (license license:gpl2+)))

(define-public r-zyp
  (package
    (name "r-zyp")
    (version "0.10-1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "zyp" version))
       (sha256
        (base32
         "03cxpkfbhrx1fy8l0dl9a13ghz93cqq6877wa8rig09ksdiivaw9"))))
    (properties `((upstream-name . "zyp")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-kendall" ,r-kendall)))
    (home-page "https://cran.r-project.org/web/packages/zyp/")
    (synopsis "Zhang + Yue-Pilon Trends Package")
    (description
     "This package contains an efficient implementation of Sen's slope
method (Sen, 1968) plus implementation of Xuebin Zhang's (Zhang, 1999) and
Yue-Pilon's (Yue, 2002) pre-whitening approaches to determining trends in
climate data.")
    (license license:lgpl2.1)))

(define-public r-zvcv
  (package
    (name "r-zvcv")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ZVCV" version))
       (sha256
        (base32
         "1npw836q2skx54843lgxvb0rfwafckjc8k8dljykm60ad3z7zak8"))))
    (properties `((upstream-name . "ZVCV")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)
       ("r-glmnet" ,r-glmnet)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-partitions" ,r-partitions)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "https://cran.r-project.org/web/packages/ZVCV/")
    (synopsis "Zero-Variance Control Variates")
    (description
     "@dfn{Zero-variance control variates} (ZV-CV) is a post-processing method
to reduce the variance of Monte Carlo estimators of expectations using the
derivatives of the log target.  Once the derivatives are available, the only
additional computational effort is in solving a linear regression problem.
This method has been extended to higher dimensions using regularisation.  This
package can be used to easily perform ZV-CV or regularised ZV-CV when a set of
samples, derivatives and function evaluations are available.  Additional
functions for applying ZV-CV to two estimators for the normalising constant of
the posterior distribution in Bayesian statistics are also supplied.")
    (license license:gpl2+)))

(define-public r-ztype
  (package
    (name "r-ztype")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ztype" version))
       (sha256
        (base32
         "0brbq2rgkl4mhjbb70kkfv47lzs66k9ppfs2klavcbripirxn5fx"))))
    (properties `((upstream-name . "ztype")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-rvest" ,r-rvest)
       ("r-stringr" ,r-stringr)))
    (home-page "https://cran.r-project.org/web/packages/ztype/")
    (synopsis "Run a Ztype game loaded with R functions")
    (description
     "How fast can you type R functions on your keyboard?  Find out by running
a @code{zty.pe} game: export R functions as instructions to type to destroy
opponents' vessels.")
    (license license:gpl3)))

(define-public r-zseq
  (package
    (name "r-zseq")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Zseq" version))
       (sha256
        (base32
         "06dndi2b1q79bmxax11bv0l5ifcz1mhpvbn90y6a6xymrgcq0ivi"))))
    (properties `((upstream-name . "Zseq")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gmp" ,r-gmp)))
    (home-page "https://cran.r-project.org/web/packages/Zseq/")
    (synopsis "Integer sequence generator")
    (description
     "This package generates well-known integer sequences.  The @code{gmp}
package is adopted for computing with arbitrarily large numbers.  Every
function has a hyperlink to its corresponding item in the @dfn{On-Line
Encyclopedia of Integer Sequences} (OEIS) in the function help page.")
    (license license:gpl3+)))

(define-public r-isoband
  (package
    (name "r-isoband")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "isoband" version))
       (sha256
        (base32
         "1r023s73qypnvpx18znr9ymylr022m90v65mz2jasn0a1kjrfcbq"))))
    (properties `((upstream-name . "isoband")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-testthat" ,r-testthat)))
    (home-page "https://github.com/wilkelab/isoband")
    (synopsis "Generate isolines and isobands from regularly spaced elevation grids")
    (description
     "This package provides a fast C++ implementation to generate contour
lines (isolines) and contour polygons (isobands) from regularly spaced grids
containing elevation data.")
    (license license:expat)))

(define-public r-ppcor
  (package
    (name "r-ppcor")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ppcor" version))
       (sha256
        (base32
         "1x9b2kb8s0bp92b17gby0jwzzr3i4cf3ap9c4nq7m8fav72g0y3a"))))
    (properties `((upstream-name . "ppcor")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ppcor/")
    (synopsis "Partial and semi-partial correlation")
    (description
     "This package provides users not only with a function to readily
calculate the higher-order partial and semi-partial correlations but also with
statistics and p-values of the correlation coefficients.")
    (license license:gpl2)))

(define-public r-hrbrthemes
  (package
    (name "r-hrbrthemes")
    (version "0.8.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hrbrthemes" version))
       (sha256
        (base32 "057h60b5p53dcyjyfwlgjc1ry968s9s64dw78p443w8717zk7zpc"))))
    (properties `((upstream-name . "hrbrthemes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-extrafont" ,r-extrafont)
       ("r-gdtools" ,r-gdtools)
       ("r-ggplot2" ,r-ggplot2)
       ("r-htmltools" ,r-htmltools)
       ("r-knitr" ,r-knitr)
       ("r-magrittr" ,r-magrittr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-scales" ,r-scales)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/hrbrmstr/hrbrthemes/")
    (synopsis "Additional themes, theme components and utilities for @code{ggplot2}")
    (description
     "This package provides a compilation of extra @code{ggplot2} themes,
scales and utilities, including a spell check function for plot label fields
and an overall emphasis on typography.")
    (license license:expat)))

(define-public r-crochet
  (package
    (name "r-crochet")
    (version "2.2.0")
    (source
     (origin
      (method url-fetch)
      (uri (cran-uri "crochet" version))
      (sha256
       (base32
        "1cbv79nyycxk6f8ldcsnn2pvgxqlnrj0qs19nhafnq2clxy863k6"))))
    (build-system r-build-system)
    (home-page "https://github.com/agrueneberg/crochet")
    (synopsis "Implementation Helper for Matrix-Like Types")
    (description
     "Functions to help implement the extraction / subsetting / indexing
function @code{[} and replacement function @code{[<-} of custom matrix-like
types (based on S3, S4, etc.), modeled as closely to the base matrix class
as possible (with tests to prove it).")
    (license license:expat)))

(define-public r-boa
  (package
    (name "r-boa")
    (version "1.1.8-2")
    (source
     (origin
      (method url-fetch)
      (uri (cran-uri "boa" version))
      (sha256
       (base32
        "04lhqk5qfvaz1jk90glr2yi5vq7cdy0w8m6g2lnzk359l9y41zhp"))))
    (properties `((upstream-name . "boa")))
    (build-system r-build-system)
    (home-page "http://www.jstatsoft.org/v21/i11")
    (synopsis "Library for @dfn{Bayesian Output Analysis Program} (BOA) for MCMC")
    (description
     "This package provides a menu-driven program and library of functions for
carrying out convergence diagnostics and statistical and graphical analysis of
@dfn{Markov chain Monte Carlo} (MCMC) sampling output.")
    (license license:gpl2+)))

(define-public r-httpcode
  (package
    (name "r-httpcode")
    (version "0.2.0")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "httpcode" version))
              (sha256
               (base32
                "06k853ihwzkcx4z3jzazpb03p91frqkwz18jy4fwr8j2nwyqbhgv"))))
    (build-system r-build-system)
    (home-page "https://github.com/sckott/httpcode")
    (synopsis "HTTP status code helper")
    (description "@code{httpcode} provides functionality for finding and
explaining the meaning of @code{HTTP} status codes.  Functions are included for
searching for codes by full or partial number, by message, and to get
appropriate dog and cat images for many status codes.")
    (license license:expat)))

(define-public r-latex2exp
  (package
    (name "r-latex2exp")
    (version "0.4.0")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "latex2exp" version))
              (sha256
               (base32
                "12nbcgfmv13k6sc6m326ras9bcvy380b7rxcxphn06r3cfkby0zw"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-stringr" ,r-stringr)
       ("r-magrittr", r-magrittr)))
    (home-page "https://github.com/stefano-meschiari/latex2exp/")
    (synopsis "Use LaTeX expressions in plots")
    (description "@code{latex2exp} parses and converts LaTeX math formulas to
R's plotmath expressions, used to enter mathematical formulas and symbols to be
rendered as text, axis labels, etc. throughout R's plotting system.")
    (license license:expat)))

(define-public r-oai
  (package
    (name "r-oai")
    (version "0.3.0")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "oai" version))
              (sha256
               (base32
                "1ipw9bq3ra66d1ddj1rylyyd20mlcb2i7phzhywra53s1fdifq1g"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-xml2" ,r-xml2)
       ("r-httr" ,r-httr)
       ("r-plyr" ,r-plyr)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/ropensci/oai/")
    (synopsis "General purpose OAI-PMH services client")
    (description "@code{oai} provides a general purpose client to work with
any @dfn{Open Archives Initiative Protocol for 'Metadata' Harvesting} (OAI-PMH)
service.  Functions are provided to work with the OAI-PMH verbs:
@code{GetRecord}, @code{Identify}, @code{ListIdentifiers},
@code{ListMetadataFormats}, @code{ListRecords}, and @code{ListSets}.")
    (license license:expat)))

(define-public r-argon2
  (package
    (name "r-argon2")
    (version "0.2-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "argon2" version))
       (sha256
        (base32
         "0kqn06rpb39jlzizjlnc5c44mfic8llrshxn7ljgmyj35lbqwxqh"))))
    (properties `((upstream-name . "argon2")))
    (build-system r-build-system)
    (home-page "https://github.com/wrathematics/argon2")
    (synopsis "Secure password hashing based on the argon2 algorithm")
    (description
     "This package provides utilities for secure password hashing via the
argon2 algorithm.")
    (license license:bsd-2)))

(define-public r-getpass
  (package
    (name "r-getpass")
    (version "0.2-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "getPass" version))
       (sha256
        (base32
         "03ydafhh0sk3rcnpr3paajyji64x2ddp6p814p9mvbmyrblcgzcc"))))
    (properties `((upstream-name . "getPass")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rstudioapi" ,r-rstudioapi)))
    (home-page "https://github.com/wrathematics/getPass")
    (synopsis "Masked user input")
    (description
     "This package provides a micro-package for reading \"passwords\", i.e.
reading user input with masking, so that the input is not displayed as it is
typed.  Currently, RStudio, the command line (every OS), and any platform
where tcltk is present are supported.")
    (license license:bsd-2)))

(define-public r-remoter
  (package
    (name "r-remoter")
    (version "0.4-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "remoter" version))
       (sha256
        (base32
         "1a7m63l8phv5jnazvdqdrqkaqjwqzaac5y4jm2jn0ypy4n8jvkfl"))))
    (properties `((upstream-name . "remoter")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-argon2" ,r-argon2)
       ("r-getpass" ,r-getpass)
       ("r-pbdzmq" ,r-pbdzmq)
       ("r-png" ,r-png)))
    (home-page "https://github.com/RBigData/remoter")
    (synopsis "Control a remote R session from a local one")
    (description
     "This package provides a set of utilities for client/server computing
with R, controlling a remote R session (the server) from a local one (the
client).")
    (license license:bsd-2)))

debug log:

solving 9dd24d164d ...
found 9dd24d164d in https://yhetil.org/guix-patches/20200328101321.9769-1-danielaluraa@gmail.com/
found 759b9263f3 in https://git.savannah.gnu.org/cgit/guix.git
preparing index
index prepared:
100644 759b9263f3ecb46aef98e31996ecffd825a5a9e8	gnu/packages/cran.scm

applying [1/1] https://yhetil.org/guix-patches/20200328101321.9769-1-danielaluraa@gmail.com/
diff --git a/gnu/packages/cran.scm b/gnu/packages/cran.scm
index 759b9263f3..9dd24d164d 100644

Checking patch gnu/packages/cran.scm...
Applied patch gnu/packages/cran.scm cleanly.

index at:
100644 9dd24d164d3a0cb233900648c37edda88fe080a4	gnu/packages/cran.scm

(*) Git path names are given by the tree(s) the blob belongs to.
    Blobs themselves have no identifier aside from the hash of its contents.^
Code repositories for project(s) associated with this public inbox

	https://git.savannah.gnu.org/cgit/guix.git

This is a public inbox, see mirroring instructions
for how to clone and mirror all data and code used for this inbox;
as well as URLs for read-only IMAP folder(s) and NNTP newsgroup(s).