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aspmx1.migadu.com; dkim=fail ("headers rsa verify failed") header.d=mdc-berlin.de header.s=mdc header.b="QECzIY/p"; dmarc=fail reason="SPF not aligned (relaxed)" header.from=mdc-berlin.de (policy=none); spf=pass (aspmx1.migadu.com: domain of "guix-patches-bounces+larch=yhetil.org@gnu.org" designates 209.51.188.17 as permitted sender) smtp.mailfrom="guix-patches-bounces+larch=yhetil.org@gnu.org" X-Migadu-Spam-Score: 7.17 Authentication-Results: aspmx1.migadu.com; dkim=fail ("headers rsa verify failed") header.d=mdc-berlin.de header.s=mdc header.b="QECzIY/p"; dmarc=fail reason="SPF not aligned (relaxed)" header.from=mdc-berlin.de (policy=none); spf=pass (aspmx1.migadu.com: domain of "guix-patches-bounces+larch=yhetil.org@gnu.org" designates 209.51.188.17 as permitted sender) smtp.mailfrom="guix-patches-bounces+larch=yhetil.org@gnu.org" X-Migadu-Queue-Id: 10A7C3DA4F X-Spam-Score: 7.17 X-Migadu-Scanner: scn1.migadu.com X-TUID: 7sC5l5xHRLs7 * gnu/packages/bioconductor.scm (r-decomplexdisease): New variable. --- gnu/packages/bioconductor.scm | 33 +++++++++++++++++++++++++++++++++ 1 file changed, 33 insertions(+) diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm index 2f2268e5e6..809ba69bc3 100644 --- a/gnu/packages/bioconductor.scm +++ b/gnu/packages/bioconductor.scm @@ -3117,6 +3117,39 @@ (define-public r-deco related to higher deregulation levels.") (license (license:fsdg-compatible "GPL (>=3)")))) +(define-public r-decomplexdisease + (package + (name "r-decomplexdisease") + (version "1.16.0") + (source (origin + (method url-fetch) + (uri (bioconductor-uri "DEComplexDisease" version)) + (sha256 + (base32 + "09a967x1rnv7byjwh29ngjhs67rgg27zblmlzx6pyqlwy5jsp89d")))) + (properties `((upstream-name . "DEComplexDisease"))) + (build-system r-build-system) + (propagated-inputs + (list r-biocparallel + r-complexheatmap + r-deseq2 + r-edger + r-rcpp + r-summarizedexperiment)) + (native-inputs (list r-knitr)) + (home-page "https://bioconductor.org/packages/DEComplexDisease") + (synopsis "Investigations of complex diseases by bi-clustering analysis") + (description + "@code{DEComplexDisease} is designed to find the @acronym{DEGs, Differential +Expressed Genes} for complex disease, which is characterized by the heterogeneous +genomic expression profiles. Different from the established DEG analysis tools, +it does not assume the patients of complex diseases to share the common DEGs. +By applying a bi-clustering algorithm, @code{DEComplexDisease} finds the DEGs +shared by as many patients. Applying the @code{DEComplexDisease} analysis +results, users are possible to find the patients affected by the same mechanism +based on the shared signatures.") + (license license:gpl3))) + (define-public r-deconvr (package (name "r-deconvr") -- 2.38.0