Is it as simple as rm'ing system-N-link from /var/guix/profiles && 'guix
gc'...?

Recreating grub.cfg with 'system reconfigure', at least, would be needed in
order to prevent fubar on trying to boot into non-existent menu
definitions. Still, that will create yet another system profile...

Fun,
Drp
-- 
(or ((,\ (x) `(,x x)) '(,\ (x) `(,x x))) (smth (that 'like)))