So, a while back I mentioned that Guix was present in Debian "experimental": https://lists.gnu.org/archive/html/guix-devel/2020-11/msg00254.html And it was useable for a brief window of time, but was broken due to some issues with guile-gnutls and guile-3.0: https://bugs.debian.org/964284 Somewhat deterred, I back-burnered it for a while while I focused on other things... Just a few days ago, I decided to attempt to get Guix into Debian's next release, and went with the fallback plan of building it against guile-2.2, and a few disabled tests later... https://tracker.debian.org/guix If all goes well, it should migrate to "bullseye" in a few days. Hopefully in a few months "bullseye" will become Debian's stable release shipping with guix! Presumeably Guix will also eventually find itself in Ubuntu and other Debian derivatives... Now on Debian you should be able to: apt install guix guix install dpkg guix environment --ad-hoc dpkg -- dpkg -i ./guix_1.2.0-3_amd64.deb It is almost like symmetry! Thanks for all the help and encouragement along the way, everyone! live well, vagrant