> Could you paste the excerpt from that log that shows the command that
> produced libdevmapper-event-lvm2mirror.so?
>
> It may be a matter of adding -ldevmapper to that command (which in turn
> will lead ld-wrapper to add the right -Wl,-rpath flag.)

Done, here is the result:

--8<---------------cut here---------------start------------->8---
> env GUIX_LD_WRAPPER_DEBUG=yes make
make -C conf device-mapper
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/conf'
make[1]: Nothing to be done for 'device-mapper'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/conf'
make -C include device-mapper
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/include'
make[1]: Nothing to be done for 'device-mapper'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/include'
make -C libdm device-mapper
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdm'
make[1]: Nothing to be done for 'device-mapper'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdm'
make -C daemons device-mapper
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons'
make -C dmeventd device-mapper
make[2]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd'
make[2]: Nothing to be done for 'device-mapper'.
make[2]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd'
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons'
make -C lib device-mapper
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/lib'
make[1]: Nothing to be done for 'device-mapper'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/lib'
make -C libdaemon device-mapper
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdaemon'
make[1]: Nothing to be done for 'device-mapper'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdaemon'
make -C man device-mapper
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/man'
make[1]: Nothing to be done for 'device-mapper'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/man'
make -C scripts device-mapper
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/scripts'
make[1]: Nothing to be done for 'device-mapper'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/scripts'
make -C tools device-mapper
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/tools'
make[1]: Nothing to be done for 'device-mapper'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/tools'
make -C udev device-mapper
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/udev'
make[1]: Nothing to be done for 'device-mapper'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/udev'
make -C conf
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/conf'
make[1]: Nothing to be done for 'all'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/conf'
make -C include
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/include'
make[1]: Nothing to be done for 'all'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/include'
make -C libdm
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdm'
make[1]: Nothing to be done for 'all'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdm'
make -C libdaemon
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdaemon'
make -C client device-mapper
make[2]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdaemon/client'
make[2]: Nothing to be done for 'device-mapper'.
make[2]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdaemon/client'
make -C client
make[2]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdaemon/client'
make[2]: Nothing to be done for 'all'.
make[2]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdaemon/client'
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/libdaemon'
make -C lib
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/lib'
make[1]: Nothing to be done for 'all'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/lib'
make -C tools
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/tools'
make[1]: Nothing to be done for 'all'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/tools'
make -C daemons
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons'
make -C dmeventd device-mapper
make[2]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd'
make[2]: Nothing to be done for 'device-mapper'.
make[2]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd'
make -C dmeventd
make[2]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd'
make -C plugins device-mapper
make[3]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins'
make[3]: Nothing to be done for 'device-mapper'.
make[3]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins'
make -C plugins
make[3]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins'
make -C lvm2 device-mapper
make[4]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/lvm2'
make[4]: Nothing to be done for 'device-mapper'.
make[4]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/lvm2'
make -C mirror device-mapper
make[4]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/mirror'
make[4]: Nothing to be done for 'device-mapper'.
make[4]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/mirror'
make -C snapshot device-mapper
make[4]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/snapshot'
make[4]: Nothing to be done for 'device-mapper'.
make[4]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/snapshot'
make -C raid device-mapper
make[4]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/raid'
make[4]: Nothing to be done for 'device-mapper'.
make[4]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/raid'
make -C thin device-mapper
make[4]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/thin'
make[4]: Nothing to be done for 'device-mapper'.
make[4]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/thin'
make -C lvm2
make[4]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/lvm2'
make[4]: Nothing to be done for 'all'.
make[4]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/lvm2'
make -C mirror
make[4]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/mirror'
gcc -shared -Wl,-soname,libdevmapper-event-lvm2mirror.so.2.02 \
	-O2  -fPIC -L../../../../daemons/dmeventd/plugins/lvm2 -Wl,--version-script,.export.sym -Wl,-z,relro -L../../../../libdm -L../../../../lib -L../../../../libdaemon/client -L../../../../daemons/dmeventd dmeventd_mirror.o   -ldevmapper-event-lvm2 -ldevmapper -o libdevmapper-event-lvm2mirror.so.2.02
guile: warning: failed to install locale
ld-wrapper: library search path: ("../../../../daemons/dmeventd/plugins/lvm2" "../../../../libdm" "../../../../lib" "../../../../libdaemon/client" "../../../../daemons/dmeventd" "/home/ambrevar/.guix-profile/lib" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../.." "/gnu/store/l4lr0f5cjd0nbsaaf8b5dmcw1a1yypr3-glibc-2.27/lib" "/gnu/store/l4lr0f5cjd0nbsaaf8b5dmcw1a1yypr3-glibc-2.27/lib")
ld-wrapper: libraries linked: ("../../../../daemons/dmeventd/plugins/lvm2/libdevmapper-event-lvm2.so" "../../../../libdm/libdevmapper.so" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../../libgcc_s.so" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../../libgcc_s.so" "/home/ambrevar/.guix-profile/lib/libc.so" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../../libgcc_s.so")
ld-wrapper: invoking `/gnu/store/srmqh29dpm50j8kj1pbqg2rgh053wgyp-binutils-2.30/bin/ld' with ("-plugin" "/gnu/store/p9swcxz49cvqfj0qj4fk7jcmad2445if-gcc-7.3.0/libexec/gcc/x86_64-unknown-linux-gnu/7.3.0/liblto_plugin.so" "-plugin-opt=/gnu/store/p9swcxz49cvqfj0qj4fk7jcmad2445if-gcc-7.3.0/libexec/gcc/x86_64-unknown-linux-gnu/7.3.0/lto-wrapper" "-plugin-opt=-fresolution=/tmp/ccStV40k.res" "-plugin-opt=-pass-through=-lgcc" "-plugin-opt=-pass-through=-lgcc_s" "-plugin-opt=-pass-through=-lgcc_s" "-plugin-opt=-pass-through=-lc" "-plugin-opt=-pass-through=-lgcc" "-plugin-opt=-pass-through=-lgcc_s" "--eh-frame-hdr" "-m" "elf_x86_64" "-shared" "-o" "libdevmapper-event-lvm2mirror.so.2.02" "/home/ambrevar/.guix-profile/lib/crti.o" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/crtbeginS.o" "-L../../../../daemons/dmeventd/plugins/lvm2" "-L../../../../libdm" "-L../../../../lib" "-L../../../../libdaemon/client" "-L../../../../daemons/dmeventd" "-L/home/ambrevar/.guix-profile/lib" "-L/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0" "-L/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../.." "-L/gnu/store/l4lr0f5cjd0nbsaaf8b5dmcw1a1yypr3-glibc-2.27/lib" "-soname" "libdevmapper-event-lvm2mirror.so.2.02" "--version-script" ".export.sym" "-z" "relro" "dmeventd_mirror.o" "-ldevmapper-event-lvm2" "-ldevmapper" "-lgcc" "--as-needed" "-lgcc_s" "--no-as-needed" "-L/gnu/store/l4lr0f5cjd0nbsaaf8b5dmcw1a1yypr3-glibc-2.27/lib" "-rpath=/gnu/store/l4lr0f5cjd0nbsaaf8b5dmcw1a1yypr3-glibc-2.27/lib" "-rpath=/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib" "-lgcc_s" "-lc" "-lgcc" "--as-needed" "-lgcc_s" "--no-as-needed" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/crtendS.o" "/home/ambrevar/.guix-profile/lib/crtn.o" "-rpath" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../.." "-rpath" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../.." "-rpath" "/home/ambrevar/.guix-profile/lib" "-rpath" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../..")
ln -s -f libdevmapper-event-lvm2mirror.so.2.02 libdevmapper-event-lvm2mirror.so
make[4]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/mirror'
make -C snapshot
make[4]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/snapshot'
make[4]: Nothing to be done for 'all'.
make[4]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/snapshot'
make -C raid
make[4]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/raid'
make[4]: Nothing to be done for 'all'.
make[4]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/raid'
make -C thin
make[4]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/thin'
make[4]: Nothing to be done for 'all'.
make[4]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins/thin'
make[3]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd/plugins'
make[2]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons/dmeventd'
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/daemons'
make -C man
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/man'
make[1]: Nothing to be done for 'all'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/man'
make -C scripts
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/scripts'
make[1]: Nothing to be done for 'all'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/scripts'
make -C udev
make[1]: Entering directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/udev'
make[1]: Nothing to be done for 'all'.
make[1]: Leaving directory '/tmp/guix-build-lvm2-2.02.177.drv-0/LVM2.2.02.177/udev'
--8<---------------cut here---------------end--------------->8---

The interesting part, manually formatted (hopefully it won't be misleading):

--8<---------------cut here---------------start------------->8---
ld-wrapper: invoking `/gnu/store/srmqh29dpm50j8kj1pbqg2rgh053wgyp-binutils-2.30/bin/ld' with (
"-plugin" "/gnu/store/p9swcxz49cvqfj0qj4fk7jcmad2445if-gcc-7.3.0/libexec/gcc/x86_64-unknown-linux-gnu/7.3.0/liblto_plugin.so"
"-plugin-opt=/gnu/store/p9swcxz49cvqfj0qj4fk7jcmad2445if-gcc-7.3.0/libexec/gcc/x86_64-unknown-linux-gnu/7.3.0/lto-wrapper"
"-plugin-opt=-fresolution=/tmp/ccStV40k.res"
"-plugin-opt=-pass-through=-lgcc"
"-plugin-opt=-pass-through=-lgcc_s"
"-plugin-opt=-pass-through=-lgcc_s"
"-plugin-opt=-pass-through=-lc"
"-plugin-opt=-pass-through=-lgcc"
"-plugin-opt=-pass-through=-lgcc_s"
"--eh-frame-hdr"
"-m" "elf_x86_64"
"-shared"
"-o" "libdevmapper-event-lvm2mirror.so.2.02"
"/home/ambrevar/.guix-profile/lib/crti.o"
"/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/crtbeginS.o"
"-L../../../../daemons/dmeventd/plugins/lvm2"
"-L../../../../libdm"
"-L../../../../lib"
"-L../../../../libdaemon/client"
"-L../../../../daemons/dmeventd"
"-L/home/ambrevar/.guix-profile/lib"
"-L/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0"
"-L/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../.."
"-L/gnu/store/l4lr0f5cjd0nbsaaf8b5dmcw1a1yypr3-glibc-2.27/lib"
"-soname" "libdevmapper-event-lvm2mirror.so.2.02"
"--version-script" ".export.sym"
"-z" "relro"
"dmeventd_mirror.o"
"-ldevmapper-event-lvm2"
"-ldevmapper"
"-lgcc"
"--as-needed"
"-lgcc_s"
"--no-as-needed"
"-L/gnu/store/l4lr0f5cjd0nbsaaf8b5dmcw1a1yypr3-glibc-2.27/lib"
"-rpath=/gnu/store/l4lr0f5cjd0nbsaaf8b5dmcw1a1yypr3-glibc-2.27/lib"
"-rpath=/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib"
"-lgcc_s"
"-lc"
"-lgcc"
"--as-needed"
"-lgcc_s"
"--no-as-needed"
"/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/crtendS.o"
"/home/ambrevar/.guix-profile/lib/crtn.o"
"-rpath" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../.."
"-rpath" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../.."
"-rpath" "/home/ambrevar/.guix-profile/lib"
"-rpath" "/gnu/store/6kp89r2i659pm6qwqw1r63pwaxfakmyc-gcc-7.3.0-lib/lib/gcc/x86_64-unknown-linux-gnu/7.3.0/../../.."
)
--8<---------------cut here---------------end--------------->8---

There does not seem to be any "-rpath" towards the output.

-- 
Pierre Neidhardt

Things are not always what they seem.
		-- Phaedrus