Hi, I tried guix build -K linphone-desktop then waited until it told me the build directory (which was /tmp/guix-build-linux-libre-5.5.10.drv-0), then $ which strace $ cd /tmp/guix-build-linux-libre-5.5.10.drv-0 $ source environment-variables $ cd source $ .....strace -f cmake . 2>&1 |grep -i bctoolbox |grep -i cmake It says, among other things, that it can't open /gnu/store/m92m6bg0xcl28djxg8h97sszf3gdl42r-bctoolbox-4.3.1/share/bctoolbox/cmake/BcToolboxConfig.cmake . So I checked that directory and it indeed does not have that file. But it does have /gnu/store/m92m6bg0xcl28djxg8h97sszf3gdl42r-bctoolbox-4.3.1/share/bctoolbox/cmake/bctoolboxConfig.cmake -- note the different case of the name. So I'd say either linphone-desktop or bctoolbox has the case wrong in some cmake file. linphone-desktop has the following line: ./CMakeLists.txt: include("${EP_bctoolbox_CONFIG_DIR}/BcToolboxConfig.cmake") ... and that line is not going to work as-is.