Hello,
I was about to open another issue with the same observation.

I'm seeing issues with the project Metabase: https://github.com/metabase/metabase. When `clojure -M:run`, it fails with:
Execution error (ClassNotFoundException) at java.net.URLClassLoader/findClass (URLClassLoader.java:476).
jakarta.servlet.AsyncContext

The problem seems to be that Clojure CLI (`clojure-tools` guix package) doesn't construct proper class path including all transitive dependencies of the project. I've tried to figure out what might be causing the issue and I suspect `maven-resolver-*` packages. Clojure CLI depends on `tools.deps` clojure lib, which itself depends on `maven-resolver-*`. There is a mention in the `tools.deps` changelog of reverting `maven-resolver-*` libs in version 0.18.1374 with comment "Revert update of Maven resolver libs - seeing resolution differences".
Here is the relevant commit:
https://github.com/clojure/tools.deps/commit/04539cd060d41a528794c04b50a6aa2293b672ce

Up until this date, `tools.deps` lists the older versions of maven-resolver-* libs in its deps.end file. Since Guix uses the latest versions of maven-resolver-* libs, I think this is causing the issue.