Thank you, the problem was solved... ~$ guix package -u lollypop The following package will be upgraded:    lollypop (dependencies or package changed) guix package: error: profile contains conflicting entries for gstreamer guix package: error:   first entry: gstreamer@1.16.2 /gnu/store/mpp1havy3dk9r1y9wmim21nxk99zfzn0-gstreamer-1.16.2 guix package: error:    ... propagated from gst-plugins-good@1.16.2 guix package: error:    ... propagated from lollypop@1.4.2 guix package: error:   second entry: gstreamer@1.16.2 /gnu/store/par5fhvqx8hssx7dh61i6cagfgppwyh0-gstreamer-1.16.2 guix package: error:    ... propagated from gst-plugins-base@1.16.2 guix package: error:    ... propagated from gst-libav@1.16.2 hint: Try upgrading both `lollypop' and `gst-libav', or remove one of them from the profile. ~$ guix package -u gst-libav The following package will be upgraded:    gst-libav (dependencies or package changed) guix package: error: profile contains conflicting entries for gstreamer guix package: error:   first entry: gstreamer@1.16.2 /gnu/store/mpp1havy3dk9r1y9wmim21nxk99zfzn0-gstreamer-1.16.2 guix package: error:    ... propagated from gst-libav@1.16.2 guix package: error:   second entry: gstreamer@1.16.2 /gnu/store/par5fhvqx8hssx7dh61i6cagfgppwyh0-gstreamer-1.16.2 guix package: error:    ... propagated from gst-plugins-base@1.16.2 guix package: error:    ... propagated from gst-plugins-ugly@1.16.2 guix package: error:    ... propagated from lollypop@1.4.2 hint: Try upgrading both `gst-libav' and `lollypop', or remove one of them from the profile. ~$ guix package -u lollypop -u gst-libav -u gtranslator The following packages will be upgraded:    gtranslator (dependencies or package changed)    lollypop    (dependencies or package changed) The following derivation will be built:    /gnu/store/2957nz5jih3rd9z9lhg00y8rba40rfwn-profile.drv applying 1 graft for /gnu/store/wf2cgbcfzgf05zg4zsx5rssf3q8w6m82-gmime-3.2.7.drv ... applying 13 grafts for /gnu/store/0q2alnyq4qfhphis5nprivwfhka7zbi9-glade-3.36.0.drv ... applying 14 grafts for /gnu/store/2whvnv5sdv957kajh5pi9f2hl4dw8vsa-libgda-5.2.10.drv ... applying 7 grafts for /gnu/store/6q2piffhp8fxazqigjsqxii9bwmkvdgf-libhandy-1.0.2.drv ... applying 12 grafts for /gnu/store/gq8ypjnnvmjvyd849wgf3q7xn4ikk21n-gtranslator-3.36.0.drv ... applying 3 grafts for /gnu/store/nrpyw5d4r48lw7lg1na4x14x963mdfdl-python-gst-1.16.2.drv ... applying 7 grafts for /gnu/store/l1s5cspy071by56h0nlrihi0py41y9rl-python-pillow-8.0.1.drv ... applying 10 grafts for /gnu/store/i4h6pg5cfh61fqgmc9czai0q6zl16m7x-sdl-1.2.15.drv ... applying 25 grafts for /gnu/store/baywnyr15jf0kmr8gi4gxkx46b1x9ldv-lollypop-1.4.2.drv ... applying 4 grafts for /gnu/store/4avb54p5x47vkbzm2kcciqhiscx317rr-libmpeg2-0.5.1.drv ... applying 4 grafts for /gnu/store/5q0vf93n91sqzs6wninxnan9ix4iql5v-gst-plugins-ugly-1.16.2.drv ... building CA certificate bundle... building fonts directory... generating GLib schema cache... creating GTK+ icon theme cache... building cache files for GTK+ input methods... building directory of Info manuals... building database for manual pages... building XDG desktop file cache... building XDG MIME database... building profile with 16 packages...