I installed guix on a debian 10 VPS with the following: cd /tmp wget https://git.savannah.gnu.org/cgit/guix.git/plain/etc/guix-install.sh chmod +x guix-install.sh ./guix-install.sh I ran guix install nginx then ran guix pull ~ $ guix pull Migrating profile generations to '/var/guix/profiles/per-user/jackson'... Updating channel 'guix' from Git repository at ' https://git.savannah.gnu.org/git/guix.git'... Building from this channel: guix https://git.savannah.gnu.org/git/guix.git 9f6efa1 substitute: /gnu/store/29jhbbg1hf557x8j53f9sxd9imlmf02a-bash-minimal-5.0.7/bin/bash: warning: setlocale: LC_ALL: cannot change locale (en_US.utf8) substitute: updating substitutes from 'https://ci.guix.gnu.org'... 100.0% /gnu/store/29jhbbg1hf557x8j53f9sxd9imlmf02a-bash-minimal-5.0.7/bin/bash: warning: setlocale: LC_ALL: cannot change locale (en_US.utf8) downloading from https://ci.guix.gnu.org/nar/lzip/x5nhgnwzhcw98f4zbzsrswirbq6bjb0g-libgcrypt-1.8.4. .. libgcrypt-1.8.4 514KiB 1.1MiB/s 00:00 [##################] 100.0% /gnu/store/29jhbbg1hf557x8j53f9sxd9imlmf02a-bash-minimal-5.0.7/bin/bash: warning: setlocale: LC_ALL: cannot change locale (en_US.utf8) downloading from https://ci.guix.gnu.org/nar/lzip/sx3097zhnrpa0y4i9r4zk4dcsgg1zw5n-guile-gcrypt-0.2.1. .. guile-gcrypt-0.2.1 102KiB 479KiB/s 00:00 [##################] 100.0% substitute: updating substitutes from 'https://ci.guix.gnu.org'... 100.0% substitute: updating substitutes from 'https://ci.guix.gnu.org'... 100.0% substitute: updating substitutes from 'https://ci.guix.gnu.org'... 100.0% applying 1 graft for /gnu/store/s1192yml13s13hjalkfmqbyc49wbm78p-guile-gcrypt-0.2.1.drv... building /gnu/store/vb3r3mfsc1vs6bqnb5d1xiylkzw8p7w4-config.scm.drv... building /gnu/store/k8a3waixwyp4av3i39bv0d4dz0iaiziw-git.scm.drv... building /gnu/store/ci9n9sj79rqd39msmcxkf56zdsfi3fp0-hash.scm.drv... building /gnu/store/1gxw16xwzvlsbyd4bfd9q3dc28xqhpzf-module-import.drv... building /gnu/store/j0xyaq7r9f023mvzmf4x4rzf9gcx3187-module-import-compiled.drv... /gnu/store/29jhbbg1hf557x8j53f9sxd9imlmf02a-bash-minimal-5.0.7/bin/bash: warning: setlocale: LC_ALL: cannot change locale (en_US.utf8) building /gnu/store/gychwa5pxm50dyp0m1809r49pg1n99fr-compute-guix-derivation.drv... Computing Guix derivation for 'x86_64-linux'... \ | - -guix pull: error: You found a bug: the program '/gnu/store/yxymqs3dj744jgqba7nsaly313v2rmdr-compute-guix-derivation' failed to compute the derivation for Guix (version: "9f6efa117cd309cb9b467b96dd2d6bb472df7abb"; system: "x86_64-linux"; host version: "1.1.0"; pull-version: 1). Please report it by email to .