There seems to be some problem installing password-store + pinentry entirely via guix home.  When I have both installed as such, I get the following outputs:

$ pinentry

OK Pleased to meet you

<C-c>

$ gpg --import ...

[prompts normally with pinentry, allows me to import]

$ pass

[my password entries]

$ pass [entry name]

gpg: decryption failed: No secret key

$ guix package -i pinentry

$ pass [entry name]

[prompts with pinentry and works normally]

So pinentry and pass seem to both be available, but don't work together unless I install pinentry via guix package.

My guix install is about two months behind, so sorry if this has already been patched.

-Zacchaeus