Hi all, Conda requires coreutils as a runtime dependency: hugo@alex ~/t $ guix shell -C conda hugo@alex ~/t [env]$ conda init bash # ignore errors hugo@alex ~/t [env]$ source ~/.bashrc sh: dirname: command not found sh: dirname: command not found The "dirname" errors go away when coreutils is added to the "guix shell" command. (Note, several other errors appear, those are reported in different bug reports. These also explain the above set of commands.) Cheers, Hugo