Hi, This is fixed in the following commit: https://git.savannah.gnu.org/cgit/guix.git/commit/?h=wip-ppc64le&id=ffcc950261c829e76f2faf6c8ea03d3fc56a20e1 The problem was in the config.log, but I didn't see it at first: "powerpc64le-guix-linux-gnu-ld: cannot find -lstdc++" Léo mentioned that it was probably a linking problem, and when I checked his commits in his own Git repository, I found this, which solved the problem: https://gitlab.com/lle-bout/guix/-/commit/070e06e8be6090a7682288c24b5686f1b578c001 However, that commit would have changed the way we link gcc-final with libstdc++ on all architectures. I have made a similar change that accomplishes the same thing, but only for powerpc64le-linux (or other Guix system types beginning with "powerpc64"). On existing Guix system types, we will continue to link the same as before. Using commit ffcc950261c829e76f2faf6c8ea03d3fc56a20e1, I was successful in building gcc-final. I'm closing this bug report. -- Chris