I've seen this a few times, and it seems like guix pull remembers old substitutes. I tried disabling one of the substitutes that guix-daemon is configured to use since it wasn't online at the time, but it tries to use it anyways: guix pull --substitute-urls='http://10.0.0.15:8081 http://10.0.0.15:8082' --branch=elfutils-0.172 --url=/home/vagrant/src/guix-bare guile: warning: failed to install locale warning: failed to install locale: Invalid argument Updating from Git repository at '/home/vagrant/src/guix-bare'... Building from Git commit b606d8625660ed035e98db7035f487e8b90b4d65... guile: warning: failed to install locale Computing Guix derivation for 'aarch64-linux'... -fetching path `/gnu/store/d1im1cqpajfyl6w205vpmw7pqv2j1y1b-libpthread-stubs-0.4'... - |Downloading http://10.0.0.157:8080/nar/gzip/d1im1cqpajfyl6w205vpmw7pqv2j1y1b-libpthread-stubs-0.4... guix substitute: error: connect: No route to host fetching path `/gnu/store/d1im1cqpajfyl6w205vpmw7pqv2j1y1b-libpthread-stubs-0.4' failed with exit code 1 fetching path `/gnu/store/yalicl04jvm63lwsnck336w96g88bi80-bash-4.4.19'... killing process 860 Backtrace: 17 (primitive-load "/gnu/store/xv6vjm9rz14c6y7ysr8rlqd6qaj?") In ice-9/boot-9.scm: 142:2 16 (dynamic-wind _ _ #) In ice-9/eval.scm: 155:9 15 (_ _) 159:9 14 (_ #(#(# "aarch64-?" ?))) In ./guix/store.scm: 1414:24 13 (run-with-store _ _ #:guile-for-build _ #:system _ # _) In ./guix/gexp.scm: / 666:2 12 (_ _) In ./guix/monads.scm: 485:9 11 (_ _) In ./guix/gexp.scm: 538:22 10 (_ _) 666:2 9 (_ _) In ./guix/monads.scm: 485:9 8 (_ _) In ./guix/gexp.scm: 538:22 7 (_ _) In ./guix/store.scm: 1333:38 6 (_ #) In ./guix/packages.scm: 878:14 5 (cache! # # ?) In unknown file: 4 (_ # # #) In ./guix/grafts.scm: 310:4 3 (graft-derivation # # ?) 188:4 2 (references-oracle # #) 197:20 1 (_ _ _) In ./guix/store.scm: 934:15 0 (_ # _ _) ./guix/store.scm:934:15: Throw to key `srfi-34' with args `(#)'. Backtrace: 9 (primitive-load "/gnu/store/xl7cb97kpmpwc49yd9s6hhk21d8?") In guix/ui.scm: 1557:12 8 (run-guix-command _ . _) In ice-9/boot-9.scm: 837:9 7 (catch _ _ # ?) 837:9 6 (catch _ _ # ?) 837:9 5 (catch _ _ # ?) In guix/scripts/pull.scm: 391:22 4 (_) In guix/store.scm: 1414:24 3 (run-with-store _ _ #:guile-for-build _ #:system _ # _) In guix/scripts/pull.scm: 239:2 2 (_ _) In ice-9/eval.scm: 191:27 1 (_ #(#(# #) ?)) In unknown file: 0 (scm-error misc-error #f "~A ~S" ("invalid build re?" ?) ?) ERROR: In procedure scm-error: ERROR: invalid build result (# /gnu/store/xv6vjm9rz14c6y7ysr8rlqd6qaj3w8v3-compute-guix-derivation bdb4230> "") live well, vagrant