Noticed this when testing guix system build with core-updates. Here's a small example which reproduces the issue: (use-modules (guix channels) (guix inferior)) (define channels (list (channel (name 'guix) (url "https://git.savannah.gnu.org/git/guix.git") (commit "e02c2f85b36ce1c733bd908a210ce1182bdd2560")))) (define inferior (inferior-for-channels channels)) (first (lookup-inferior-packages inferior "linux-libre" "5.2.21")) If you save that as a file then attempt to build it: → guix build -f test.scm Updating channel 'guix' from Git repository at 'https://git.savannah.gnu.org/git/guix.git'... Backtrace: 4 (primitive-load "/gnu/store/8mv5bpjgxg9c369xnbb5rf1kv9r?") In ice-9/eval.scm: 619:8 3 (_ #(#(#(#(#(#(#(#(#(#(#(?) ?) ?) ?) ?) ?) ?) ?) ?) ?) ?)) 182:19 2 (proc #(#(#(#(#(#(#(#(#(#(# ?) ?) ?) ?) ?) ?) ?) ?) ?) ?)) 142:16 1 (compile-top-call # ?) In unknown file: 0 (%resolve-variable (7 . call-with-new-thread) #) ERROR: In procedure %resolve-variable: Unbound variable: call-with-new-thread guix build: error: You found a bug: the program '/gnu/store/8mv5bpjgxg9c369xnbb5rf1kv9r6z5hw-compute-guix-derivation' failed to compute the derivation for Guix (version: "e02c2f85b36ce1c733bd908a210ce1182bdd2560"; system: "x86_64-linux"; host version: "a8cb1e72ef351330d1521833c1b270dcc0da593f"; pull-version: 1). Please report it by email to .