This problem was resolved for me with the trick from the thread at
help-guix "OBS Studio memory leak":

Robby Zambito <…> writes:

> Guillaume Le Vaillant <…> writes:
>
>> It looks like an issue with the shader cache of mesa.
>> After clearing it, I don't see the memory leak anymore.
>>
>> Could you try doing a "rm -r $HOME/.cache/mesa_shader_cache/*" and see
>> if it also solves the issue for you?
>
> This worked for me! Thank you!

It also works for me.

Can we somehow automate this solution?

Best wishes,
Arne
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