Since I submitted this bug I have done a `guix pull --no-substitutes`
and tried do reconfigure the system and the build of webkitgtk fails.

Leo Famulari writes:
> Are you using any channels?

There is no `~/.config/guix/channels.scm` file.

There are no extra channel showing in the output of `guix pull
--list-generations`. The output for the current generation is:

```
Generation 8    Apr 22 2021 18:20:30    (current)
  guix c22204c
    repository URL: https://git.savannah.gnu.org/git/guix.git
    branch: master
    commit: c22204cf7bf12056c43e5da2fd99c95866143ddc
  5 new packages: cl-pathname-utils, daemonize,
    ecl-pathname-utils, kraken2, sbcl-pathname-utils
  25 packages upgraded: cpupower@5.11.16,
    exfatprogs@1.1.1, freefall@5.11.16,
    guix-build-coordinator@0-25.c49b1c8, icedove-wayland@78.10.0,
    icedove@78.10.0, libretro-lowresnx@1.2, libupnp@1.14.6,
    libxlsxwriter@1.0.3, linux-libre-bpf@5.11.16,
    linux-libre-headers@5.11.16, linux-libre@5.11.16,
    openconnect-sso@0.7.3, openvpn@2.5.2, perf@5.11.16, retroarch@1.9.1,
    tmon@5.11.16, turbostat@5.11.16, waybar@0.9.7,
    wine-staging-patchset-data@6.6, wine-staging@6.6,
    wine64-staging@6.6, wireshark@3.4.5, wxmaxima@21.04.0,
    x86-energy-perf-policy@5.11.16
```

> Or maybe custom packages via GUIX_PACKAGE_PATH?

`echo $GUIX_PACKAGE_PATH` outputs an empty line.

> Or anything else we should know about?

What else should I look into?

> Can you send the file
> '/gnu/store/b1vs7n6dvmsrk9510q8hqjnq6m9mvrm3-webkitgtk-2.32.0.drv'
> as an attachment?

The derivation is attached.