The recent move of agetty-service into #base-services caused serial login to stop working here. Previously this worked ... (agetty-service (agetty-configuration (tty "ttyS1") (baud-rate "115200"))) First I tried removing the lines above. Then I tried ... (define %my-services (modify-services %base-services (agetty-service-type config => (agetty-configuration (tty "ttyS1") (baud-rate "115200"))))) I can confirm that ... root@g1 /home/g1# sudo echo 123 > /dev/ttyS1 ... produces "123" on the serial line. guix (GNU Guix) 0.14.0.2487-58246 config attached (my G54) TIA - George