Hi Ludovic, Not really answering your question, but would user namespaces be an option for you? If so, might be a simpler option. Thank you for the suggestion, this does look interesting. However, the original use-case of using guix in a non-root scenario is no longer relevant to me: I was convincing enough to get guix root-installed on all relevant machines on which I do not have root access. So I can enjoy guix properly, now. However, I could very well imagine guix to be used on a per-user basis, acting on some sub-directory of $HOME. Afterall, many (most?) desktop-systems are used by a single user - or so I would argue… On the original topic - I recently learned that the mechanisms proot employs might just not work on all systems. So the issue may not per-se have been with guix, but with proot. I’m no expert on the subject though, and didn’t dig deeper yet. Best regards, Florian ​