Hi Guix,

On Guix System

  guix ecab53c
    repository URL: https://git.savannah.gnu.org/git/guix.git
    branch: master
    commit: ecab53c320b1584a08f811b17a92bd9a50a50ff3

it's impossible to install jupyter in a new profile because it tries to propagate two different versions of python-ipython, you should be able to reproduce with:

$ guix package -p /tmp/tmp-profile -i jupyter
The following package will be installed:
   jupyter 1.0.0

guix package: error: profile contains conflicting entries for python-ipython
guix package: error:   first entry: python-ipython@7.9.0 /gnu/store/z0yarar134q6sziqncjdlfg2h2w5b2yh-python-ipython-7.9.0
guix package: error:    ... propagated from python-ipywidgets@7.5.1
guix package: error:    ... propagated from jupyter@1.0.0
guix package: error:   second entry: python-ipython@7.9.0 /gnu/store/avmg5jd7kccchxadsd9c7zq0p3shlk3w-python-ipython-7.9.0
guix package: error:    ... propagated from python-qtconsole@4.4.3
guix package: error:    ... propagated from jupyter@1.0.0
hint: You cannot have two different versions or variants of `jupyter' in the same profile.

The conflict seems to be caused because:

- /gnu/store/avmg5jd7kccchxadsd9c7zq0p3shlk3w-python-ipython-7.9.0 depends on python-prompt-toolkit@3.0.5

- /gnu/store/z0yarar134q6sziqncjdlfg2h2w5b2yh-python-ipython-7.9.0 depends on python-prompt-toolkit@2.0.7

This change seems to be introduced with 32ba87c14fd5e5b54d95211cd9a159d568ce7c67 , which updates python-prompt-toolkit to 3.0.5 and to prevent python-ipywidgets, python-jupyter-console and python-widgetsnbextension tests from crashing builds them with python-prompt-toolkit@2.0.7.

Giacomo