Hi,

The fact that Valgrind doesn't work out of the box seems to already be
known[1] but I didn't find any bugreports on it.

The workaround[1] mentioned is extremely useful but it's far from ideal.

For instance if you have a software that uses Valgrind in its tests
(for instance in 'make check') you end up having to add something like
that in the native-inputs to refer to the right glibc debug symbols
directory:
> ("libc:debug", (@@ (gnu packages commencement) glibc-final) "debug")

In my case I'm using guix and a guix.scm for testing the build of a
library I maintain and I also wanted to automatically check for memory
safety.

I was helped a lot on #guix to solve the issue I had, and during that
mjw suggested to fix the root issue by keeping "the .symtab in ld.so"
without the full debug info (to save space) and if I understood right
mjw is a valgrind contributor.

According to mjw that could be done with strip -g or strip -d or -strip
-S.

Reference:
----------
[1]https://lists.gnu.org/archive/html/help-guix/2022-03/msg00036.html

Denis.