Greetings! I've hit the following issue.

1. $ guile --version
guile (GNU Guile) 3.0.9

2.  uname -a
Linux ein 6.2.9-arch1-1 #1 SMP PREEMPT_DYNAMIC Thu, 30 Mar 2023 14:51:14
+0000 x86_64 GNU/Linux

3. $ pacman -Qi guile
Name            : guile
Version         : 3.0.9-1
Description     : Portable, embeddable Scheme implementation written in C
Architecture    : x86_64

4. When loading (i am not sure about the stage) module which contains in
the body system* call Guile hangs on futex operation. The code to reproduce
the behavior.

$ cat a.scm
(add-to-load-path ".")
(import (b))
(display "hello world from SCM!")
(newline)

$ cat b.scm
(define-module (b))
(system* "echo" "hello world from SYS!")

$ guile a.scm
HANGS HERE!

But if system* is changed to open-pipe*, like so:
$ cat b.scm
(define-module (b) #:use-module (ice-9 popen))
(close-pipe (open-pipe* OPEN_WRITE "echo" "hello world from SYS!"))

everything seems ok:
$ guile a.scm
hello world from SYS!
Hello World from SCM!

- MB, with best regards.