This bug occurs in Ubuntu 20.10 when both guile-2.2-dev and 
guile-3.0-dev packages are installed. An autotools project reproducing 
the bug is included. In order to reproduce the bug give commands 
"autoreconf -ivf" and "./configure".

I get the following output from configure:

---

...

configure: checking for guile 2.2
configure: found guile 2.2
checking for guile-2.0.14... no
checking for guile2.0.14... no
checking for guile-2.0... no
checking for guile2.0... no
checking for guile-2... no
checking for guile2... no
checking for guile... /usr/bin/guile
configure: error: found development files for Guile 2.2, but 
/usr/bin/guile has effective version 3.0

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      - Tommi Höynälänmaa