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From: John McCabe <john@nospam.assen.demon.co.uk>
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Subject: Re: Reading file in emacs
Date: Wed, 23 Jun 2010 10:05:54 +0100
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On Tue, 22 Jun 2010 22:05:18 -0600, Qiang Guo <mcknight0219@gmail.com>
wrote:

>Here comes my second question, how to process file
>in a byte-by-byte fashion, for instance, instead of editing
>a line of text, I'd like to edit directly their binary
>representations ?

M-x hexl-mode

Does that help?