Hello! I'm on Windows, using Python3 from Anaconda distrib. I've set option '(python-shell-interpreter "py") When doing M-x run-python I get Warning (python): Your ‘python-shell-interpreter’ doesn’t seem to support readline, yet ‘python-shell-completion-native-enable’ was t and "py" is not part of the ‘python-shell-completion-native-disabled-interpreters’ list. Native completions have been disabled locally. Python 3.6.1 |Anaconda 4.4.0 (64-bit)| (default, May 11 2017, 13:25:24) [MSC v.1900 64 bit (AMD64)] on win32 Type "help", "copyright", "credits" or "license" for more information. >>> python.el: native completion setup failed >>> It is expected that Python completion works out-of-the-box, without warnings. Ready to provide any additional info, Andrey Paramonov In GNU Emacs 25.3.1 (x86_64-w64-mingw32) of 2017-09-17 built on LAPHROAIG Windowing system distributor 'Microsoft Corp.', version 6.3.9600 Configured using: 'configure --without-dbus --without-compress-install 'CFLAGS=-O2 -static -g3'' Configured features: XPM JPEG TIFF GIF PNG RSVG SOUND NOTIFY ACL GNUTLS LIBXML2 ZLIB TOOLKIT_SCROLL_BARS Important settings: value of $LANG: RUS locale-coding-system: cp1252 Major mode: Special Minor modes in effect: shell-dirtrack-mode: t tooltip-mode: t global-eldoc-mode: t electric-indent-mode: t mouse-wheel-mode: t tool-bar-mode: t menu-bar-mode: t file-name-shadow-mode: t global-font-lock-mode: t font-lock-mode: t auto-composition-mode: t auto-encryption-mode: t auto-compression-mode: t buffer-read-only: t line-number-mode: t transient-mark-mode: t Recent messages: For information about GNU Emacs and the GNU system, type C-h C-a. Making completion list... You can run the command run-python with C-c C-p Shell native completion is disabled, using fallback Load-path shadows: None found. Features: (shadow sort mail-extr thingatpt emacsbug message dired rfc822 mml mml-sec epg mm-decode mm-bodies mm-encode mail-parse rfc2231 mailabbrev gmm-utils mailheader sendmail rfc2047 rfc2045 ietf-drums mail-utils warnings compile tramp-cache python tramp-sh tramp tramp-compat auth-source cl-seq eieio eieio-core cl-macs gnus-util mm-util help-fns mail-prsvr password-cache tramp-loaddefs trampver ucs-normalize shell pcomplete format-spec advice json map comint ring ansi-color finder-inf info tex-site package epg-config seq byte-opt gv bytecomp byte-compile cl-extra help-mode easymenu cconv cl-loaddefs pcase cl-lib time-date mule-util tooltip eldoc electric uniquify ediff-hook vc-hooks lisp-float-type mwheel dos-w32 ls-lisp disp-table w32-win w32-vars term/common-win tool-bar dnd fontset image regexp-opt fringe tabulated-list newcomment elisp-mode lisp-mode prog-mode register page menu-bar rfn-eshadow timer select scroll-bar mouse jit-lock font-lock syntax facemenu font-core frame cl-generic cham georgian utf-8-lang misc-lang vietnamese tibetan thai tai-viet lao korean japanese eucjp-ms cp51932 hebrew greek romanian slovak czech european ethiopic indian cyrillic chinese charscript case-table epa-hook jka-cmpr-hook help simple abbrev minibuffer cl-preloaded nadvice loaddefs button faces cus-face macroexp files text-properties overlay sha1 md5 base64 format env code-pages mule custom widget hashtable-print-readable backquote w32notify w32 multi-tty make-network-process emacs) Memory information: ((conses 16 238322 10475) (symbols 56 24227 0) (miscs 48 129 150) (strings 32 31786 7274) (string-bytes 1 989742) (vectors 16 40361) (vector-slots 8 734537 6096) (floats 8 256 140) (intervals 56 426 0) (buffers 976 24))