my apologies for the insistence, but please take a look a this, it’s a very simple change and although wrt python.el it just removes an annoying message ("Your ‘python-shell-interpreter’ doesn’t seem to support readline") and avoids disabling native completion altogether (which, anyway, as I’ve discussed elsewhere, I believe doesn’t add much in terms of features as it adds in terms of problems), wrt org-babel the problem is actually serious since trying to evaluate a python code block without first blacklisting python from native completion freezes emacs to death and seemingly a restart is needed. Of course, org-babel should be more robust in this regard but some help from python.el won’t hurt.