In gnus-sum.el, gnus attempts to add a tool-bar item for (gnus-summary-tick-article-forward "flag-followup" nil :visible nil) pointing to an image file "flag-followup" which is not supplied. This does not have any ill effects as far as I can see, but perhaps it is not what's intended. There is an image file called "followup" - is that the right file? Also, I noticed that the icon in mail/save shows up differently from the rest - it has black bars on top and bottom and shows up differently when selected. (See attached screenshot. I tested this in a 22 branch build as well.) I have no idea what causes this behavior.