diff --git a/lisp/progmodes/python.el b/lisp/progmodes/python.el
index ddedbdb..d6bb724 100644
--- a/lisp/progmodes/python.el
+++ b/lisp/progmodes/python.el
@@ -1609,7 +1609,8 @@ the output."
                       (setq output-buffer (concat output-buffer string))
                       "")))))
     (python-shell-send-string string process msg)
-    (accept-process-output process)
+    (with-local-quit
+      (accept-process-output process))
     (replace-regexp-in-string
      (if (> (length python-shell-prompt-output-regexp) 0)
          (format "\n*%s$\\|^%s\\|\n$"