Here a tricky bug, and probably is related #50641 and I never seems this behaviour before fix for #50534. When I have open emacs one another virtual screen, it has openned magit status buffer, and I've make a click and hold on emacs's icon on desk => it shows "Application not responding" (see screenshot). Not always, but ofthen enough. When I switch to actual virtual screen which has emacs => it responses well. 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