> > is there a way to disable a region every time a command has been run
> > on it? For example, I mark a region, M-x eval-region and I would like
> > that the region selection disappear.
> 
> What' you're asking is the normal behavior, usually.

That was going to be my answer: this is the normal
behavior of the command loop.  Generally, if you 
_don't_ want the region deactivated after each
command you need to do something, such as call
`deactivate-mark' or reset var `deactivate-mark'
to nil.