(defun make-lines-invisible (regexp &optional arg)
  "Make all lines matching a regexp invisible and intangible.
With a prefix arg, make it visible again.  It is not necessary
that REGEXP matches the whole line; if a hit is found, the
affected line gets automatically selected.

This command affects the whole buffer."
  (interactive "MRegexp: \nP")
  (let (ov
	ovs)
    (cond
     ((equal arg '(4))
      (setq ovs (overlays-in (point-min) (point-max)))
      (mapc (lambda (o)
	      (if (overlay-get o 'make-lines-invisible)
		  (delete-overlay o)))
	    ovs))
     (t
      (save-excursion
	(goto-char (point-min))
	(while (re-search-forward regexp nil t)
	  (setq ov (make-overlay (line-beginning-position)
				 (line-end-position)))
	  (overlay-put ov 'make-lines-invisible t)
	  (overlay-put ov 'invisible t)
	  (overlay-put ov 'intangible t)))))))

(global-set-key "\C-cz" 'make-lines-invisible)