It seems that in NS (on OS X), font names have become case-sensitive since Emacs 22 (Carbon at least). Setting a face to use family "lucida grande" or "monaco" doesn't work - it results in frames full of empty boxes (because the font can't be loaded, I presume). I also found that the face, if you do (customize-face 'default), have their :family attributes set to "Monotype_Sorts". This font doesn't seem to exist on my system. Given that people have faces configured in their custom-file, I don't think a sudden case-sensitivity is going to make our users happy, whatever good reasons for this design choice there might exist. (I can try to write a bug report if the above isn't sufficiently detailed.)