Steps to reproduce: 1. Use regular C-x C-f /ssh:remote:/path/on/remote. The remote machine is a GNU Linux machine too. 2. Then open eshell using M-x eshell on the remote machine. 3. Type `top` in the eshell prompt. You see the following error in a *top* buffer: ..: 1: exec: /ssh:remote:/bin/top: not found Process /ssh:remote:/bin/top exited abnormally with code 127 Expected behavior: Since /bin/top is present on the remote (which can be verified if you do the same in M-x shell), I'd expect top to work there via eshell. I've verified that top in eshell does work if the eshell is run on the local machine (no ssh and tramp-mode). In GNU Emacs 27.1 (build 1, x86_64-pc-linux-gnu, GTK+ Version 3.22.30, cairo version 1.15.10)  of 2020-08-26 built on lgw01-amd64-030 Repository revision: a2fc5f02361a34ff7322032ce027c8bc4cc3b25a Repository branch: master Windowing system distributor 'The X.Org Foundation', version 11.0.11906000 System Description: Ubuntu 18.04.5 LTS Recent messages: (no useful messages) Configured using:  'configure --prefix= --prefix=/snap/emacs/current/usr --with-xwidgets  --with-x-toolkit=gtk3 --without-xaw3d --with-modules --with-cairo  'CFLAGS= -isystem/build/emacs/parts/emacs/install/usr/include -O2'  'CPPFLAGS= -isystem/build/emacs/parts/emacs/install/usr/include'  'LDFLAGS= -L/build/emacs/parts/emacs/install/lib  -L/build/emacs/parts/emacs/install/usr/lib  -L/build/emacs/parts/emacs/install/lib/x86_64-linux-gnu  -L/build/emacs/parts/emacs/install/usr/lib/x86_64-linux-gnu'' Configured features: XPM JPEG TIFF GIF PNG RSVG CAIRO SOUND GPM DBUS GSETTINGS GLIB NOTIFY INOTIFY ACL LIBSELINUX GNUTLS LIBXML2 FREETYPE HARFBUZZ M17N_FLT LIBOTF ZLIB TOOLKIT_SCROLL_BARS GTK3 X11 XDBE XIM MODULES THREADS XWIDGETS LIBSYSTEMD JSON PDUMPER LCMS2 GMP Important settings:   value of $LANG: en_US.UTF-8   locale-coding-system: utf-8-unix Major mode: Go Minor modes in effect:   subword-mode: t   global-magit-file-mode: t   magit-file-mode: t   magit-auto-revert-mode: t   global-git-commit-mode: t   lsp-diagnostics-mode: t   lsp-modeline-workspace-status-mode: t   lsp-modeline-diagnostics-mode: t   lsp-modeline-code-actions-mode: t   dap-tooltip-mode: t   dap-ui-many-windows-mode: t   dap-ui-controls-mode: t   dap-ui-mode: t   treemacs-filewatch-mode: t   treemacs-follow-mode: t   treemacs-git-mode: deferred   treemacs-fringe-indicator-mode: t   dap-auto-configure-mode: t   dap-mode: t   lsp-completion-mode: t   guru-mode: t   pdf-occur-global-minor-mode: t   lsp-ui-mode: t   lsp-ui-doc-mode: t   lsp-ui-sideline-mode: t   lsp-managed-mode: t   lsp-mode: t   TeX-PDF-mode: t   TeX-source-correlate-mode: t   yas-global-mode: t   yas-minor-mode: t   global-flycheck-mode: t   flycheck-mode: t   global-hl-todo-mode: t   hl-todo-mode: t   which-function-mode: t   global-company-mode: t   company-mode: t   helm-mode: t   helm-descbinds-mode: t   helm-ff-cache-mode: t   helm--remap-mouse-mode: t   async-bytecomp-package-mode: t   ivy-mode: t   erc-truncate-mode: t   erc-track-mode: t   erc-spelling-mode: t   pixel-scroll-mode: t   editorconfig-mode: t   global-diff-hl-mode: t   diff-hl-mode: t   winner-mode: t   global-undo-tree-mode: t   undo-tree-mode: t   whitespace-mode: t   global-anzu-mode: t   anzu-mode: t   projectile-mode: t   flyspell-mode: t   volatile-highlights-mode: t   global-hl-line-mode: t   super-save-mode: t   recentf-mode: t   savehist-mode: t   save-place-mode: t   show-smartparens-global-mode: t   show-smartparens-mode: t   smartparens-mode: t   global-auto-revert-mode: t   delete-selection-mode: t   prelude-mode: t   shell-dirtrack-mode: t   which-key-mode: t   tooltip-mode: t   global-eldoc-mode: t   eldoc-mode: t   electric-indent-mode: t   mouse-wheel-mode: t   file-name-shadow-mode: t   global-font-lock-mode: t   font-lock-mode: t   auto-composition-mode: t   auto-encryption-mode: t   auto-compression-mode: t   size-indication-mode: t   column-number-mode: t   line-number-mode: t   transient-mark-mode: t Load-path shadows: None found. Features: (shadow sort mail-extr emacsbug sendmail eieio-opt speedbar sb-image ezimage dframe help-fns radix-tree go-mode find-file hackernews mm-archive wdired move-text pyimport shut-up url-cache url-http url-gw url-auth dired-aux iso-transl pdf-sync pdf-annot pdf-outline pdf-links pdf-history mule-util cal-move helm-ag conf-mode man dockerfile-mode helm-sys misearch multi-isearch swiper pcmpl-unix pcmpl-gnu finder lisp-mnt helm-x-files helm-for-files helm-bookmark helm-adaptive easy-kill novice em-unix em-term term ehelp em-script em-prompt em-ls em-hist em-pred em-glob em-dirs esh-var em-cmpl em-basic em-banner em-alias esh-mode helm-command vc-mtn vc-hg vc-bzr vc-src vc-sccs vc-svn vc-cvs vc-rcs diff-hl-dired image-file helm-external ffap magit-gitignore virtualenvwrapper subword-mode-expansions cap-words superword subword bug-reference magit-bookmark magit-submodule magit-obsolete magit-popup magit-blame magit-stash magit-reflog magit-bisect magit-push magit-pull magit-fetch 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prelude-yaml prelude-xml nxml-mode-expansions rng-nxml rng-valid nxml-mode nxml-outln nxml-rap html-mode-expansions sgml-mode dom prelude-web web-mode-expansions smartparens-html web-mode disp-table prelude-ts typescript-mode prelude-scss prelude-shell sh-script smie executable prelude-scheme geiser prelude-ruby prelude-python prelude-perl prelude-org ox-odt rng-loc rng-uri rng-parse rng-match rng-dt rng-util rng-pttrn nxml-parse nxml-ns nxml-enc xmltok nxml-util ox-latex ox-icalendar ox-html table ox-ascii ox-publish ox org-element avl-tree ob-python ob-ditaa ob-plantuml prelude-lsp lsp-ui lsp-ui-flycheck lsp-ui-doc xwidget image-mode exif goto-addr lsp-ui-imenu lsp-ui-peek lsp-ui-sideline face-remap lsp-mode spinner network-stream puny nsm rmc smartparens-markdown markdown-mode lv inline dash-functional bindat lsp-protocol ht prelude-latex company-auctex latex-mode-expansions latex latex-flymake flymake-proc flymake warnings tex-ispell tex-style tex dbus ido-completing-read+ memoize minibuf-eldef crm texmathp helm-bibtex bibtex-completion org-capture the-org-mode-expansions smartparens-org org ob ob-tangle ob-ref ob-lob ob-table ob-exp org-macro org-footnote org-src ob-comint org-pcomplete org-list org-faces org-entities noutline outline org-version ob-emacs-lisp ob-core ob-eval org-table ol org-keys org-compat org-macs org-loaddefs cal-menu calendar cal-loaddefs biblio biblio-download biblio-dissemin biblio-ieee biblio-hal biblio-dblp biblio-crossref biblio-arxiv timezone biblio-doi biblio-core let-alist url-queue ido f parsebib bibtex helm-net xml smartparens-latex prelude-js indium indium-list-sources indium-scratch indium-interaction indium-chrome indium-nodejs url url-proxy url-privacy url-expand url-methods url-history url-cookie url-domsuf url-util mailcap indium-repl indium-debugger indium-debugger-litable js2-refactor js2r-paredit js2r-conveniences js2r-conditionals js2r-wrapping js2r-functions yasnippet-snippets yasnippet js2r-vars 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prelude-helm helm-projectile helm-files helm-tags helm-buffers helm-occur helm-grep helm-regexp helm-locate helm-types helm-imenu helm-utils helm-help helm async-bytecomp helm-global-bindings helm-easymenu helm-source helm-multi-match helm-lib async helm-config prelude-ivy two-column ivy flx ivy-faces ivy-overlay colir color prelude-erc erc-truncate erc-track erc-match erc-autoaway erc-spelling erc-notify erc-networks erc-log erc-goodies erc erc-backend erc-compat erc-loaddefs prelude-linux novak-personal-premodules exec-path-from-shell prelude-global-keybindings pixel-scroll prelude-editor editorconfig operate-on-number calc-bin calc-ext calc calc-loaddefs calc-macs diff-hl smartrep vc-dir ewoc vc vc-dispatcher diff-mode winner undo-tree diff eshell esh-cmd esh-ext esh-opt esh-proc esh-io esh-arg esh-module esh-groups esh-util re-builder whitespace tabify browse-kill-ring midnight ediff ediff-merg ediff-mult ediff-wind ediff-diff ediff-help ediff-init ediff-util dired-x dired 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backquote threads dbusbind inotify lcms2 dynamic-setting system-font-setting font-render-setting xwidget-internal cairo move-toolbar gtk x-toolkit x multi-tty make-network-process emacs) Memory information: ((conses 16 4065706 537288)  (symbols 48 111678 3)  (strings 32 596944 94542)  (string-bytes 1 19459691)  (vectors 16 204511)  (vector-slots 8 3321598 557608)  (floats 8 979 1543)  (intervals 56 718451 5959)  (buffers 1000 161))