diff --git a/lisp/progmodes/gdb-mi.el b/lisp/progmodes/gdb-mi.el
index 66fc4b1..037f64a 100644
--- a/lisp/progmodes/gdb-mi.el
+++ b/lisp/progmodes/gdb-mi.el
@@ -3998,7 +3998,7 @@ gdb-invalidate-disassembly
          (file (gdb-mi--field frame 'fullname))
          (line (gdb-mi--field frame 'line)))
     (if file
-      (format "-data-disassemble -f %s -l %s -n -1 -- 0" file line)
+      (format "-data-disassemble -f %s -l %s -n -1 -- 0" (file-local-name file) line)
     ;; If we're unable to get a file name / line for $PC, simply
     ;; follow $PC, disassembling the next 10 (x ~15 (on IA) ==
     ;; 150 bytes) instructions.